The Experts below are selected from a list of 41412 Experts worldwide ranked by ideXlab platform
M Coutinho A Da Silva - One of the best experts on this subject based on the ideXlab platform.
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retrospective study on equine uterine Fungal Isolates and antiFungal susceptibility patterns 1999 2011
Equine Veterinary Journal, 2012Co-Authors: Katherine A. Beltaire, S. H. Cheong, M Coutinho A Da SilvaAbstract:Summary Reasons for performing study: Knowledge of commonly encountered fungi infecting the mare's reproductive tract and their respective drug susceptibilities should improve treatment efficacy in mares with Fungal endometritis. This is particularly important when practitioners need to start empiric treatment before culture results are complete. Objective: To report the spectrum of Fungal Isolates from uterine samples from mares with reproductive problems and their respective antiFungal susceptibilities. Methods: Equine uterine samples submitted to the Cornell University Animal Health Diagnostic Centre for Fungal culture between July 1999 and June 2011 were reviewed. Each mare's reproductive history, Fungal culture results, antiFungal susceptibilities and concurrent aerobic culture results were evaluated. Patterns of antiFungal susceptibility and resistance were assessed over time. Results: One hundred and two Fungal Isolates were cultured from 92 uterine samples from mares with reproductive problems. Yeast (69%) and mould with septated hyphae (26%) were the most common Isolates. Ninety-five to 100% of all Fungal Isolates were susceptible to the polyenes, while response to the azoles varied with 47–81% of Fungal Isolates displaying susceptibility. Yeast Isolates were 100% susceptible to the polyenes and least susceptible to miconazole (48%) while Isolates of mould with septated hyphae were most susceptible to natamycin (100%) and least susceptible to fluconazole (0%). From July 1999 to June 2005 and July 2005 to June 2011, yeast demonstrated increasing resistance to miconazole, while mould with septated hyphae demonstrated increasing resistance to ketoconazole. Conclusions and clinical relevance: Results from this study suggest that polyenes are effective against uterine Fungal Isolates in vitro and may be the empiric treatment of choice for Fungal endometritis. Isolate resistance to specific azoles increased over time.
Katherine A. Beltaire - One of the best experts on this subject based on the ideXlab platform.
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Retrospective study on equine uterine Fungal Isolates and antiFungal susceptibility patterns (1999–2011)
Equine veterinary journal. Supplement, 2012Co-Authors: Katherine A. Beltaire, S. H. Cheong, M.a. Coutinho Da SilvaAbstract:Summary Reasons for performing study: Knowledge of commonly encountered fungi infecting the mare's reproductive tract and their respective drug susceptibilities should improve treatment efficacy in mares with Fungal endometritis. This is particularly important when practitioners need to start empiric treatment before culture results are complete. Objective: To report the spectrum of Fungal Isolates from uterine samples from mares with reproductive problems and their respective antiFungal susceptibilities. Methods: Equine uterine samples submitted to the Cornell University Animal Health Diagnostic Centre for Fungal culture between July 1999 and June 2011 were reviewed. Each mare's reproductive history, Fungal culture results, antiFungal susceptibilities and concurrent aerobic culture results were evaluated. Patterns of antiFungal susceptibility and resistance were assessed over time. Results: One hundred and two Fungal Isolates were cultured from 92 uterine samples from mares with reproductive problems. Yeast (69%) and mould with septated hyphae (26%) were the most common Isolates. Ninety-five to 100% of all Fungal Isolates were susceptible to the polyenes, while response to the azoles varied with 47–81% of Fungal Isolates displaying susceptibility. Yeast Isolates were 100% susceptible to the polyenes and least susceptible to miconazole (48%) while Isolates of mould with septated hyphae were most susceptible to natamycin (100%) and least susceptible to fluconazole (0%). From July 1999 to June 2005 and July 2005 to June 2011, yeast demonstrated increasing resistance to miconazole, while mould with septated hyphae demonstrated increasing resistance to ketoconazole. Conclusions and clinical relevance: Results from this study suggest that polyenes are effective against uterine Fungal Isolates in vitro and may be the empiric treatment of choice for Fungal endometritis. Isolate resistance to specific azoles increased over time.
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retrospective study on equine uterine Fungal Isolates and antiFungal susceptibility patterns 1999 2011
Equine Veterinary Journal, 2012Co-Authors: Katherine A. Beltaire, S. H. Cheong, M Coutinho A Da SilvaAbstract:Summary Reasons for performing study: Knowledge of commonly encountered fungi infecting the mare's reproductive tract and their respective drug susceptibilities should improve treatment efficacy in mares with Fungal endometritis. This is particularly important when practitioners need to start empiric treatment before culture results are complete. Objective: To report the spectrum of Fungal Isolates from uterine samples from mares with reproductive problems and their respective antiFungal susceptibilities. Methods: Equine uterine samples submitted to the Cornell University Animal Health Diagnostic Centre for Fungal culture between July 1999 and June 2011 were reviewed. Each mare's reproductive history, Fungal culture results, antiFungal susceptibilities and concurrent aerobic culture results were evaluated. Patterns of antiFungal susceptibility and resistance were assessed over time. Results: One hundred and two Fungal Isolates were cultured from 92 uterine samples from mares with reproductive problems. Yeast (69%) and mould with septated hyphae (26%) were the most common Isolates. Ninety-five to 100% of all Fungal Isolates were susceptible to the polyenes, while response to the azoles varied with 47–81% of Fungal Isolates displaying susceptibility. Yeast Isolates were 100% susceptible to the polyenes and least susceptible to miconazole (48%) while Isolates of mould with septated hyphae were most susceptible to natamycin (100%) and least susceptible to fluconazole (0%). From July 1999 to June 2005 and July 2005 to June 2011, yeast demonstrated increasing resistance to miconazole, while mould with septated hyphae demonstrated increasing resistance to ketoconazole. Conclusions and clinical relevance: Results from this study suggest that polyenes are effective against uterine Fungal Isolates in vitro and may be the empiric treatment of choice for Fungal endometritis. Isolate resistance to specific azoles increased over time.
S. H. Cheong - One of the best experts on this subject based on the ideXlab platform.
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Retrospective study on equine uterine Fungal Isolates and antiFungal susceptibility patterns (1999–2011)
Equine veterinary journal. Supplement, 2012Co-Authors: Katherine A. Beltaire, S. H. Cheong, M.a. Coutinho Da SilvaAbstract:Summary Reasons for performing study: Knowledge of commonly encountered fungi infecting the mare's reproductive tract and their respective drug susceptibilities should improve treatment efficacy in mares with Fungal endometritis. This is particularly important when practitioners need to start empiric treatment before culture results are complete. Objective: To report the spectrum of Fungal Isolates from uterine samples from mares with reproductive problems and their respective antiFungal susceptibilities. Methods: Equine uterine samples submitted to the Cornell University Animal Health Diagnostic Centre for Fungal culture between July 1999 and June 2011 were reviewed. Each mare's reproductive history, Fungal culture results, antiFungal susceptibilities and concurrent aerobic culture results were evaluated. Patterns of antiFungal susceptibility and resistance were assessed over time. Results: One hundred and two Fungal Isolates were cultured from 92 uterine samples from mares with reproductive problems. Yeast (69%) and mould with septated hyphae (26%) were the most common Isolates. Ninety-five to 100% of all Fungal Isolates were susceptible to the polyenes, while response to the azoles varied with 47–81% of Fungal Isolates displaying susceptibility. Yeast Isolates were 100% susceptible to the polyenes and least susceptible to miconazole (48%) while Isolates of mould with septated hyphae were most susceptible to natamycin (100%) and least susceptible to fluconazole (0%). From July 1999 to June 2005 and July 2005 to June 2011, yeast demonstrated increasing resistance to miconazole, while mould with septated hyphae demonstrated increasing resistance to ketoconazole. Conclusions and clinical relevance: Results from this study suggest that polyenes are effective against uterine Fungal Isolates in vitro and may be the empiric treatment of choice for Fungal endometritis. Isolate resistance to specific azoles increased over time.
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retrospective study on equine uterine Fungal Isolates and antiFungal susceptibility patterns 1999 2011
Equine Veterinary Journal, 2012Co-Authors: Katherine A. Beltaire, S. H. Cheong, M Coutinho A Da SilvaAbstract:Summary Reasons for performing study: Knowledge of commonly encountered fungi infecting the mare's reproductive tract and their respective drug susceptibilities should improve treatment efficacy in mares with Fungal endometritis. This is particularly important when practitioners need to start empiric treatment before culture results are complete. Objective: To report the spectrum of Fungal Isolates from uterine samples from mares with reproductive problems and their respective antiFungal susceptibilities. Methods: Equine uterine samples submitted to the Cornell University Animal Health Diagnostic Centre for Fungal culture between July 1999 and June 2011 were reviewed. Each mare's reproductive history, Fungal culture results, antiFungal susceptibilities and concurrent aerobic culture results were evaluated. Patterns of antiFungal susceptibility and resistance were assessed over time. Results: One hundred and two Fungal Isolates were cultured from 92 uterine samples from mares with reproductive problems. Yeast (69%) and mould with septated hyphae (26%) were the most common Isolates. Ninety-five to 100% of all Fungal Isolates were susceptible to the polyenes, while response to the azoles varied with 47–81% of Fungal Isolates displaying susceptibility. Yeast Isolates were 100% susceptible to the polyenes and least susceptible to miconazole (48%) while Isolates of mould with septated hyphae were most susceptible to natamycin (100%) and least susceptible to fluconazole (0%). From July 1999 to June 2005 and July 2005 to June 2011, yeast demonstrated increasing resistance to miconazole, while mould with septated hyphae demonstrated increasing resistance to ketoconazole. Conclusions and clinical relevance: Results from this study suggest that polyenes are effective against uterine Fungal Isolates in vitro and may be the empiric treatment of choice for Fungal endometritis. Isolate resistance to specific azoles increased over time.
Jiang Tao - One of the best experts on this subject based on the ideXlab platform.
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Biosorption and bioaccumulation of thallium by thallium-tolerant Fungal Isolates.
Environmental science and pollution research international, 2015Co-Authors: Jialong Sun, Xiao Zou, Tangfu Xiao, Yanlong Jia, Zengping Ning, Min Sun, Yizhang Liu, Jiang TaoAbstract:Little is known about the biosorption and bioaccumulation capacity of thallium (Tl) by microorganisms that occur in Tl-polluted soil. The present study focused on characterizing the biosorption and bioaccumulation of Tl by Tl-tolerant fungi isolated from Tl-polluted soils. Preliminary data showed a positive correlation between the biomass and the biosorbed Tl content. The Tl-tolerant strains were capable of bioaccumulating Tl, up to 7189 mg kg−1 dry weight. The subcellular distribution of Tl showed obvious compartmentalization: cytoplasm ≫ cell wall > organelle. The majority of Tl (up to 79 %) was found in the cytoplasm, suggesting that intracellular compartmentalization appeared to be responsible for detoxification. These findings further suggest the applicability of the Fungal Isolates for cleanup of Tl in Tl-polluted water and soil.
Yubhisha Dabas - One of the best experts on this subject based on the ideXlab platform.
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MALDI-TOF mass spectrometry for rapid identification of clinical Fungal Isolates based on ribosomal protein biomarkers.
Journal of microbiological methods, 2014Co-Authors: Ashutosh Panda, Anup Ghosh, Bijay Ranjan Mirdha, Immaculata Xess, Saikat Paul, Jyotish Chandra Samantaray, Alagiri Srinivasan, Shehla Khalil, Neha Rastogi, Yubhisha DabasAbstract:This study aimed to evaluate the identification of clinical Fungal Isolates (yeast and molds) by protein profiling using Matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF/MS). A total of 125 clinical Fungal culture Isolates (yeast and filamentous fungi) were collected. The test set included 88 yeast Isolates (Candida albicans, Candida glabrata, Candida guilliermondii, Candida kefyr, Candida krusei, Candida parapsilosis, Candida rugosa, Candida tropicalis and Cryptococcus neoformans) and 37 Isolates of molds (Alternaria spp., Aspergillus flavus, Aspergillus fumigatus, Aspergillus niger, Cunninghamella spp., Histoplasma capsulatum, Microsporum gypseum, Microsporum nanum, Rhizomucor spp. and Trichophyton spp.). The correlation between MALDI TOF MS and conventional identification for all these 125 Fungal Isolates included in the study was 87.2% at the species level and 90.4% at the genus level. MALDI TOF MS results revealed that the correlation in yeast (n=88) identification was 100% both at the genus and species levels whereas, the correlation in mold (n=37) identification was more heterogeneous i.e. 10.81% Isolates had correct identification up to the genus level, 56.7% Isolates had correct identification both at the genus and species levels, whereas 32.42% Isolates were deemed Not Reliable Identification (NRI). But, with the modification in sample preparation protocol for molds, there was a significant improvement in identification. 86.4% Isolates had correct identification till the genus and species levels whereas, only 2.7% Isolates had Not Reliable Identification. In conclusion, this study demonstrates that MALDI-TOF MS could be a possible alternative to conventional techniques both for the identification and differentiation of clinical Fungal Isolates. However, the main limitation of this technique is that MS identification could be more precise only if the reference spectrum of the Fungal species is available in the database.
