The Experts below are selected from a list of 216 Experts worldwide ranked by ideXlab platform
Gordon R. Stairs - One of the best experts on this subject based on the ideXlab platform.
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Quantitative studies on the infection of Galleria mellonella with a nuclear polyhedrosis virus of Bombyx mori
Journal of Invertebrate Pathology, 1991Co-Authors: Gordon R. StairsAbstract:Abstract The nuclear polyhedrosis virus of Bombyx mori was found to be infectious for Galleria mellonella after a single injection of virions released from polyhedra. After one replication in G. mellonella the resulting free virions were highly infectious for both host species. These results are discussed.
Françoise Botterel - One of the best experts on this subject based on the ideXlab platform.
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Galleria mellonella as a screening tool to study virulence factors of Aspergillus fumigatus.
Virulence, 2021Co-Authors: Marie-fleur Durieux, Élise Melloul, Sana Jemel, Lolita Roisin, Marie-laure Dardé, Jacques Guillot, Éric Dannaoui, Françoise BotterelAbstract:The invertebrate Galleria mellonella has increasingly and widely been used in the last few years to study complex host-microbe interactions. Aspergillus fumigatus is one of the most pathogenic fungi causing life-threatening diseases in humans and animals. Galleria mellonella larvae has been proven as a reliable model for the analysis of pathogenesis and virulence factors, enable to screen a large number of A. fumigatus strains. This review describes the different uses of G. mellonella to study A. fumigatus and provides a comparison of the different protocols to trace fungal pathogenicity. The review also includes a summary of the diverse mutants tested in G. mellonella, and their respective contribution to A. fumigatus virulence. Previous investigations indicated that G. mellonella should be considered as an interesting tool even though a mammalian model may be required to complete and verify initial data.
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Galleria mellonella as a screening tool to study virulence factors of Aspergillus fumigatus
Virulence, 2021Co-Authors: Marie-fleur Durieux, Élise Melloul, Sana Jemel, Lolita Roisin, Marie-laure Dardé, Jacques Guillot, Éric Dannaoui, Françoise BotterelAbstract:The invertebrate Galleria mellonella has increasingly and widely been used in the last few years to study complex host–microbe interactions. Aspergillus fumigatus is one of the most pathogenic fung...
Aare Kuusik - One of the best experts on this subject based on the ideXlab platform.
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Metabolic cost of ventilating movements in pupae of Tenebrio molitor and Galleria mellonella studied by direct calorimetry
Thermochimica Acta, 1996Co-Authors: Margus Harak, Ingolf Lamprecht, Aare KuusikAbstract:Abstract The energetic cost of periodically occurring rhythmic body movements in pupae of the mealworm Tenebrio molitor and the wax moth Galleria mellonella was estimated by the use of direct calorimetry. The motions affect tracheal ventilation and/or accelerate hemolymph circulation. The contribution of muscular activity to the total specific heat production rate in 46 to 52 h old pupae of Tenebrio molitor and Galleria mellonella was 1.24% and 0.9%, respectively. The energetic cost of stereotyped body motions serving diverse functions formed a negligible part (less than 3%) of the total energy consumed during pupal development.
Marie-fleur Durieux - One of the best experts on this subject based on the ideXlab platform.
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Galleria mellonella as a screening tool to study virulence factors of Aspergillus fumigatus.
Virulence, 2021Co-Authors: Marie-fleur Durieux, Élise Melloul, Sana Jemel, Lolita Roisin, Marie-laure Dardé, Jacques Guillot, Éric Dannaoui, Françoise BotterelAbstract:The invertebrate Galleria mellonella has increasingly and widely been used in the last few years to study complex host-microbe interactions. Aspergillus fumigatus is one of the most pathogenic fungi causing life-threatening diseases in humans and animals. Galleria mellonella larvae has been proven as a reliable model for the analysis of pathogenesis and virulence factors, enable to screen a large number of A. fumigatus strains. This review describes the different uses of G. mellonella to study A. fumigatus and provides a comparison of the different protocols to trace fungal pathogenicity. The review also includes a summary of the diverse mutants tested in G. mellonella, and their respective contribution to A. fumigatus virulence. Previous investigations indicated that G. mellonella should be considered as an interesting tool even though a mammalian model may be required to complete and verify initial data.
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Galleria mellonella as a screening tool to study virulence factors of Aspergillus fumigatus
Virulence, 2021Co-Authors: Marie-fleur Durieux, Élise Melloul, Sana Jemel, Lolita Roisin, Marie-laure Dardé, Jacques Guillot, Éric Dannaoui, Françoise BotterelAbstract:The invertebrate Galleria mellonella has increasingly and widely been used in the last few years to study complex host–microbe interactions. Aspergillus fumigatus is one of the most pathogenic fung...
Jean-baptiste Ferdy - One of the best experts on this subject based on the ideXlab platform.
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a high throughput technique to quantify bacterial pathogens virulence on the insect model Galleria mellonella
Journal of Microbiological Methods, 2018Co-Authors: Nathalie Parthuisot, Jacques Rouquette, Jean-baptiste FerdyAbstract:We combined spectrophotometry and an original statistical approach to infer bacteria virulence, using the lepidoptera Galleria mellonella as a host model. With this method, it is possible to use a microplate reader to automatize data collection on host survival on batches of 96 samples. The method also allows measurement of pathogen multiplication if GFP labelled bacterial strains are used.
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A high-throughput technique to quantify pathogens' virulence on the insect model Galleria mellonella
2018Co-Authors: Nathalie Parthuisot, Jacques Rouquette, Jean-baptiste FerdyAbstract:We combined spectrophotometry and an original statistical approach to infer bacteria virulence, using the lepidoptera Galleria mellonella as a host model. With this method, it is possible to use a microplate reader to automatize data collection on both pathogens multiplication and host survival on batches of 96 samples.
