The Experts below are selected from a list of 138 Experts worldwide ranked by ideXlab platform
Romana Ceovic - One of the best experts on this subject based on the ideXlab platform.
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chancroid lymphoGranuloma venereum Granuloma Inguinale genital herpes simplex infection and molluscum contagiosum
Clinics in Dermatology, 2014Co-Authors: Aleksandra Bastajuzbasic, Romana CeovicAbstract:Chancroid, lymphoGranuloma venereum, and Granuloma Inguinale may be considered as tropical venereal diseases. These diseases were a major diagnostic and therapeutic challenge in past centuries. Currently, patients with these bacterial infections that are endemic to the tropics occasionally consult with dermatologists in temperate climates. Due to the increasing frequency of travel to the tropics for tourism and work, as well as the increasing number of immigrants from these areas, it is important for dermatologists practicing in temperate climates to be familiar with the dermatologic manifestations of such infections, to be prepared to diagnose these diseases, and to treat these patients. All three "tropical" infections respond well to prompt and appropriate antimicrobial treatment, although herpes progenitalis still cannot be cured, and the number of people infected keeps growing; moreover, genital herpes can be transmitted by viral shedding before and after the visual signs or symptoms. Acyclovir, valacyclovir, and famciclovir can shorten outbreaks and make them less severe or even stop them from happening. There is currently no etiologic treatment for molluscum contagiosum, and the majority of treatment options are mechanical, causing a certain degree of discomfort. The molluscum contagiosum virus, unlike the other infectious agents mentioned, does not invade the skin.
K De Wolf - One of the best experts on this subject based on the ideXlab platform.
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mucocutaneous manifestations of chancroid lymphoGranuloma venereum and Granuloma Inguinale
American Family Physician, 1994Co-Authors: Jean Goens, Robert A Schwartz, K De WolfAbstract:The sexually transmitted diseases chancroid, lymphoGranuloma venereum and Granuloma Inguinale should be familiar to physicians who care for patients at risk. The mucocutaneous manifestations of these three diseases must be distinguished from the lesions of other venereal diseases, such as primary syphilis and genital herpes simplex. Human immunodeficiency virus (HIV) infection should always be considered in patients with any venereal disease, since sexually transmitted diseases often occur together. Furthermore, the genital erosions that occur in patients with these three disorders may predispose them to HIV infection.
J P Figueroa - One of the best experts on this subject based on the ideXlab platform.
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genital ulcers etiology clinical diagnosis and associated human immunodeficiency virus infection in kingston jamaica
Clinical Infectious Diseases, 1999Co-Authors: Frieda Behets, Stephen A Morse, A R Brathwaite, T Hyltonkong, Chengyen Chen, Irving F Hoffman, J B Weiss, G Dallabetta, Myron S Cohen, J P FigueroaAbstract:Individuals presenting consecutively with genital ulcers in Kingston, Jamaica, underwent serological testing for human immunodeficiency virus (HIV) infection, chlamydial infection, and syphilis. Ulcer material was analyzed by multiplex polymerase chain reaction (M-PCR) analysis. DNA from herpes simplex virus (HSV), Haemophilus ducreyi, and Treponema pallidum was detected in 158 (52.0%), 72 (23.7%), and 31 (10.2%) of 304 ulcer specimens. Of the 304 subjects, 67 (22%) were HIV-seropositive and 64 (21%) were T. pallidum ‐ seroreactive. Granuloma Inguinale was clinically diagnosed in nine (13.4%) of 67 ulcers negative by M-PCR analysis and in 12 (5.1%) of 237 ulcers positive by M-PCR analysis (P A .03). LymphoGranuloma venereum was clinically diagnosed in eight patients. Compared with M-PCR analysis, the sensitivity and specificity of a clinical diagnosis of syphilis, herpes, and chancroid were 67.7%, 53.8%, and 75% and 91.2%, 83.6%, and 75.4%, respectively. Reactive syphilis serology was 74% sensitive and 85% specific compared with M-PCR analysis. Reported contact with a prostitute in the preceding 3 months was associated with chancroid (P A .009), reactive syphilis serology (P A .011), and HIV infection (P A .007). The relatively poor accuracy of clinical and locally available laboratory diagnoses pleads for syndromic management of genital ulcers in Jamaica. Prevention efforts should be intensified.
Rob E Dorrington - One of the best experts on this subject based on the ideXlab platform.
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sentinel surveillance of sexually transmitted infections in south africa a review
Sexually Transmitted Infections, 2005Co-Authors: Leigh F Johnson, David Coetzee, Rob E DorringtonAbstract:Objectives: To review studies of sexually transmitted infection (STI) prevalence in South Africa between 1985 and 2003 in selected sentinel populations. To examine how STI prevalence varies between populations and to identify the limitations of the existing data. Methods: Studies of the prevalence of syphilis, chancroid, Granuloma Inguinale, lymphoGranuloma venereum, gonorrhoea, chlamydia, trichomoniasis, bacterial vaginosis, candidiasis, and herpes simplex virus type 2 (HSV-2) were considered. Results were included if they related to women attending antenatal clinics or family planning clinics, commercial sex workers, individuals in the general population (household surveys), patients with STIs, patients with genital ulcer disease (GUD), or men with urethritis. Results: High STI prevalence rates have been measured, particularly in the case of HSV-2, trichomoniasis, bacterial vaginosis and candidiasis. The aetiological profile of GUD appears to be changing, with more GUD caused by HSV-2 and less caused by chancroid. The prevalence of gonorrhoea and syphilis is highest in “high risk” groups such as sex workers and attenders of STI clinics, but chlamydia and trichomoniasis prevalence levels are not significantly higher in these groups than in women attending antenatal clinics. Conclusions: The prevalence of STIs in South Africa is high, although there is extensive variability between regions. There is a need for STI prevalence data that are more nationally representative and that can be used to monitor prevalence trends more reliably.
Aleksandra Bastajuzbasic - One of the best experts on this subject based on the ideXlab platform.
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chancroid lymphoGranuloma venereum Granuloma Inguinale genital herpes simplex infection and molluscum contagiosum
Clinics in Dermatology, 2014Co-Authors: Aleksandra Bastajuzbasic, Romana CeovicAbstract:Chancroid, lymphoGranuloma venereum, and Granuloma Inguinale may be considered as tropical venereal diseases. These diseases were a major diagnostic and therapeutic challenge in past centuries. Currently, patients with these bacterial infections that are endemic to the tropics occasionally consult with dermatologists in temperate climates. Due to the increasing frequency of travel to the tropics for tourism and work, as well as the increasing number of immigrants from these areas, it is important for dermatologists practicing in temperate climates to be familiar with the dermatologic manifestations of such infections, to be prepared to diagnose these diseases, and to treat these patients. All three "tropical" infections respond well to prompt and appropriate antimicrobial treatment, although herpes progenitalis still cannot be cured, and the number of people infected keeps growing; moreover, genital herpes can be transmitted by viral shedding before and after the visual signs or symptoms. Acyclovir, valacyclovir, and famciclovir can shorten outbreaks and make them less severe or even stop them from happening. There is currently no etiologic treatment for molluscum contagiosum, and the majority of treatment options are mechanical, causing a certain degree of discomfort. The molluscum contagiosum virus, unlike the other infectious agents mentioned, does not invade the skin.
