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Sari, Dini Anggita - One of the best experts on this subject based on the ideXlab platform.
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Gambaran Tingkat Kecemasan Pada Pasien Ginjal Kronik Yang Menjalani Hemodialisa Di Rumah Sakit Umum Universitas Kristen Indonesia 2018
2019Co-Authors: Sari, Dini AnggitaAbstract:Pasien gagal ginjal yang menjalani hemodialisa akan bergantungan pada mesin dialisa seumur hidupnya dan penyesuaian diri terhadap kondisi sakit mengakibatkan terjadinya perubahan kehidupan pasien. Perubahan dalam kehidupan merupakan suatu pemicu terjadinya stress. Terjadinya stress dikarenakan oleh stressor, yang dirasakan dan dipersepsikan individu, merupakan suatu ancaman yang dapat menimbulkan kecemasan. Tujuan dari penelitian ini adalah untuk mengetahui gambaran tingkat kecemasan pada pasien penyakit ginjal kronik yang menjalani hemodialisis di Rumah Sakit Umum Universitas Kristen Indonesia. Penelitian ini menggunakan metode descriptif analitik dengan besar sampel 38 orang. Hasil penelitian ini didapatkan: 5 orang (13,2%) tidak cemas, 29 orang (76,3%) dengan kecemasan ringan hingga sedang, 4 orang (10,5%) dengan kecemasan berat dan tidak ada yang mengalami kecemasan sangat berat. Berdasarkan hasil penelitian dapat disimpulkan bahwa pasien ginjal kronik yang menjalani hemodialisa di Rumah Sakit Umum Universitas Kristen Indonesia mayoritas memiliki kecemasan derajat ringan hingga sedang. Kata kunci : kecemasan, penyakit ginjal kronik, hemodialisa. Renal failure patients who go through Hemodialysis will depend on the dialysis machine for the remainder of the patient’s life and adapting to the condition will trigger changes in the patient’s life. Sudden changes in life is a stress trigger. Stress is caused by stressors, which are felt and perceived by an individual, is a threat that can cause anxiety. This research aims to know the anxiety levels in chronic renal failure patients who go through Hemodialysis in Christian University of Indonesia Hospital. This research uses descriptive analysis method with 38 samples. Results include: 5 people (13,2%) is not anxious, 29 people (76,3%) suffer mild to moderate anxiety, 4 people (10,5%) suffer severe anxiety, and no one suffers from extreme anxiety. According to research results, it can be concluded that chronic renal failure patients who go through Hemodialysis in Christian University of Indonesia Hospital has a majority of people who suffer mild to moderate anxiety. Keywords: Anxiety, Chronic Renal Failure, Hemodialysis
Michael Walsh - One of the best experts on this subject based on the ideXlab platform.
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effect of frequent nocturnal Hemodialysis vs conventional Hemodialysis on left ventricular mass and quality of life a randomized controlled trial
JAMA, 2007Co-Authors: Bruce F Culleton, Michael Walsh, Marcello Tonelli, Scott Klarenbach, Garth Mortis, Narine Scottdouglas, Robert R Quinn, Sarah Donnelly, Matthias G Friedrich, Andreas KumarAbstract:ContextMorbidity and mortality rates in Hemodialysis patients remain excessive. Alterations in the delivery of dialysis may lead to improved patient outcomes.ObjectiveTo compare the effects of frequent nocturnal Hemodialysis vs conventional Hemodialysis on change in left ventricular mass and health-related quality of life over 6 months.Design, Setting, and ParticipantsA 2-group, parallel, randomized controlled trial conducted at 2 Canadian university centers between August 2004 and December 2006. A total of 52 patients undergoing Hemodialysis were recruited.InterventionParticipants were randomly assigned in a 1:1 ratio to receive nocturnal Hemodialysis 6 times weekly or conventional Hemodialysis 3 times weekly.Main Outcome MeasuresThe primary outcome was change in left ventricular mass, as measured by cardiovascular magnetic resonance imaging. The secondary outcomes were patient-reported quality of life, blood pressure, mineral metabolism, and use of medications.ResultsFrequent nocturnal Hemodialysis significantly improved the primary outcome (mean left ventricular mass difference between groups, 15.3 g, 95% confidence interval [CI], 1.0 to 29.6 g; P = .04). Frequent nocturnal Hemodialysis did not significantly improve quality of life (difference of change in EuroQol 5-D index from baseline, 0.05; 95% CI, −0.07 to 0.17; P = .43). However, frequent nocturnal Hemodialysis was associated with clinically and statistically significant improvements in selected kidney-specific domains of quality of life (P = .01 for effects of kidney disease and P = .02 for burden of kidney disease). Frequent nocturnal Hemodialysis was also associated with improvements in systolic blood pressure (P = .01 after adjustment) and mineral metabolism, including a reduction in or discontinuation of antihypertensive medications (16/26 patients in the nocturnal Hemodialysis group vs 3/25 patients in the conventional Hemodialysis group; P < .001) and oral phosphate binders (19/26 patients in the nocturnal Hemodialysis group vs 3/25 patients in the conventional dialysis group; P < .001). No benefit in anemia management was seen with nocturnal Hemodialysis.ConclusionThis preliminary study revealed that, compared with conventional Hemodialysis (3 times weekly), frequent nocturnal Hemodialysis improved left ventricular mass, reduced the need for blood pressure medications, improved some measures of mineral metabolism, and improved selected measures of quality of life.Trial Registrationisrctn.org Identifier: ISRCTN25858715
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effect of frequent nocturnal Hemodialysis vs conventional Hemodialysis on left ventricular mass and quality of life a randomized controlled trial
JAMA, 2007Co-Authors: Bruce F Culleton, Michael Walsh, Marcello Tonelli, Scott Klarenbach, Garth Mortis, Narine Scottdouglas, Robert R Quinn, Sarah Donnelly, Matthias G Friedrich, Andreas KumarAbstract:ContextMorbidity and mortality rates in Hemodialysis patients remain excessive. Alterations in the delivery of dialysis may lead to improved patient outcomes.ObjectiveTo compare the effects of frequent nocturnal Hemodialysis vs conventional Hemodialysis on change in left ventricular mass and health-related quality of life over 6 months.Design, Setting, and ParticipantsA 2-group, parallel, randomized controlled trial conducted at 2 Canadian university centers between August 2004 and December 2006. A total of 52 patients undergoing Hemodialysis were recruited.InterventionParticipants were randomly assigned in a 1:1 ratio to receive nocturnal Hemodialysis 6 times weekly or conventional Hemodialysis 3 times weekly.Main Outcome MeasuresThe primary outcome was change in left ventricular mass, as measured by cardiovascular magnetic resonance imaging. The secondary outcomes were patient-reported quality of life, blood pressure, mineral metabolism, and use of medications.ResultsFrequent nocturnal Hemodialysis significantly improved the primary outcome (mean left ventricular mass difference between groups, 15.3 g, 95% confidence interval [CI], 1.0 to 29.6 g; P = .04). Frequent nocturnal Hemodialysis did not significantly improve quality of life (difference of change in EuroQol 5-D index from baseline, 0.05; 95% CI, −0.07 to 0.17; P = .43). However, frequent nocturnal Hemodialysis was associated with clinically and statistically significant improvements in selected kidney-specific domains of quality of life (P = .01 for effects of kidney disease and P = .02 for burden of kidney disease). Frequent nocturnal Hemodialysis was also associated with improvements in systolic blood pressure (P = .01 after adjustment) and mineral metabolism, including a reduction in or discontinuation of antihypertensive medications (16/26 patients in the nocturnal Hemodialysis group vs 3/25 patients in the conventional Hemodialysis group; P < .001) and oral phosphate binders (19/26 patients in the nocturnal Hemodialysis group vs 3/25 patients in the conventional dialysis group; P < .001). No benefit in anemia management was seen with nocturnal Hemodialysis.ConclusionThis preliminary study revealed that, compared with conventional Hemodialysis (3 times weekly), frequent nocturnal Hemodialysis improved left ventricular mass, reduced the need for blood pressure medications, improved some measures of mineral metabolism, and improved selected measures of quality of life.Trial Registrationisrctn.org Identifier: ISRCTN25858715
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a systematic review of the effect of nocturnal Hemodialysis on blood pressure left ventricular hypertrophy anemia mineral metabolism and health related quality of life
Kidney International, 2005Co-Authors: Michael Walsh, Marcello Tonelli, Bruce F Culleton, Braden J MannsAbstract:A systematic review of the effect of nocturnal Hemodialysis on blood pressure, left ventricular hypertrophy, anemia, mineral metabolism, and health-related quality of life. Background Nocturnal Hemodialysis is a novel form of dialysis where patients perform dialysis 6 nights per week while they sleep. Multiple publications report significant improvements in selected clinical outcomes, although the strength of these results is limited by shortcomings in study design. A systematic review of the current available literature was undertaken to examine the effect of nocturnal Hemodialysis on key health outcomes. Methods An inclusive search of medical databases was undertaken to identify all nocturnal Hemodialysis studies. These results were manually reviewed for relevance to nocturnal Hemodialysis and its impact on the following predefined health outcomes: blood pressure control, left ventricular hypertrophy, anemia, mineral metabolism, and health related quality of life. Case reports, short-term studies ( Results Of the initial 270 studies identified, only 14 met inclusion/exclusion criteria. No studies examining the impact of nocturnal Hemodialysis on mortality were identified. All studies reported improved blood pressure control after conversion to nocturnal Hemodialysis. Data regarding the other health outcomes of interest revealed mixed results. Conclusion Nocturnal Hemodialysis is a potential alternative to conventional intermittent Hemodialysis. Before significant resources are invested in initiating nocturnal Hemodialysis programs, further data on mortality and cardiovascular morbidity, preferably from randomized clinical trials, are required.
-, Arina Maliya, S.kep., Ns. M.si.med - One of the best experts on this subject based on the ideXlab platform.
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Gambaran Tingkat Depresi Berdasarkan Karakteristik Personal pada Pasien Gagal Ginjal Kronik yang Menjalani Hemodialisa di RS PKU Aisyiyah Boyolali
2020Co-Authors: Fathonah, Evisiana Oktafiani, -, Arina Maliya, S.kep., Ns. M.si.medAbstract:Chronic renal failure (CRF) is a failure of kidney function to maintain metabolism and fluid and electrolyte balance due to the progressive destruction of kidney structure with the accumulation of metabolic waste (uremic toxic) in the blood. Data from Indonesia Renal Registry (IRR) in 2015, the number of CKD patients who enrolled in Hemodialysis units continues to increase by 10% each year. In 2018 the prevalence of chronic kidney failure in Indonesia reaches 3.8%. Hemodialysis is one of the dialysis therapies used to remove fluids and waste products from the body when the kidneys are unable and accurately able to carry out the process. The goal of Hemodialysis is to help extend the life of patients by reducing symptoms caused by impairment due to decreased kidney function. Although Hemodialysis is able to extend the life of the patient, patients who do Hemodialysis must be able to make considerable adjustments to Hemodialysis. Previous studies reported that the majority of patients with chronic kidney failure were poor sleepers as a result of increased plasma toxicity, anemia, and hypoxia. Besides other psychological factors are anxiety, anxiety, fear and depression are very significant factors associated with disturbed sleep patterns in patients with chronic kidney failureThe existence of changes in patients with chronic kidney failure undergoing Hemodialysis will cause psychological disorders, one of which is depression. Depression itself is a feeling of loss of energy and interest, feelings of guilt, difficulty concentrating, loss of appetite, and thoughts about death or suicide. The purpose of the research itself is to find out how the level of depression in CKD patients undergoing Hemodialysis therapy based on personal characteristics. The population in this study 38 respondents with a sample of 30 respondents. Research using quantitative descriptive design, sampling using total sampling techniques, the instrument used is Beck Depression Scale-II. Data analysis uses univariate. The results of the study of some of the characteristics of patients, mostly adults aged above 45 years (63.3%), the sex of most women (53.3%), education mostly elementary school (50%), the work of most farmers (90%), marital status most were married (90%), mostly 9-12 months old Hemodialysis (46.7%). Chronic failure disease patients Hemodialysis mostly experienced minimal depression (43.3%). Keywords: Depression, Chronic Kidney Failure, Hemodialysi
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GAMBARAN KECEMASAN PASIEN YANG TERPASANG CIMINO DAN FEMORAL PADA PASIEN HEMODIALISA DI RSUD IR. SOEKARNO SUKOHARJO
2020Co-Authors: Lisnawati Fina, -, Arina Maliya, S.kep., Ns. M.si.medAbstract:Hemodialysis is a process of filtering blood through a dializer machine to remove metabolic waste in the body of patients with chronic kidney failure. The Hemodialysis process requires installing a cannulation device in the form of a keteter that can be passed through the blood at high speed through one lumen and returned to a different lumen. The cannulation device in Hemodialysis is classified as either a temporary entry point (short term) or an intermediate entry point (long term). Long-term Hemodialysis entry point is the arteriovenous fistula (AVF) which is connected directly to the original artery with the superficial vein. AVF is formed from a radial arterial fistula to the cephalic vein (Brescia-Cimino fistula). Whereas the short-term entry pathway for critical patients, femoral venous cannulation to begin dialysis is quick and safe. Installation of cannulation instruments in the Hemodialysis procedure can cause anxiety effects on patients. This study aims to identify the level of anxiety and characteristics in Hemodialysis patients with cimino and femoral cannulation devices. This research is a descriptive study with a survey method. The study population was Hemodialysis patients ≤1 years. The sample technique used was total sampling with the acquisition of a sample of 30 respondents installed cimino and 20 respondents installed femoral. Anxiety is measured by the Hamilton Anxiety Rating Scale (HARS) instrument. The conclusion of this study is that the majority of Hemodialysis patients both cimino and femoral paired are both in severe anxiety with each cimino of 11 respondents (36.7%) and femoral of 8 respondents (40%). Factors that influence anxiety in Hemodialysis patients are social demographic factors, namely age, sex, length of Hemodialysis, level of education and employment status. This study suggests that motivation and family support counseling be given to minimize anxiety in Hemodialysis patients, especially Hemodialysis patients for less than one year
Elaine Rutherford - One of the best experts on this subject based on the ideXlab platform.
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defining myocardial tissue abnormalities in end stage renal failure with cardiac magnetic resonance imaging using native t1 mapping
Kidney International, 2016Co-Authors: Elaine Rutherford, Mohammed A Talle, Kenneth Mangion, Elizabeth Bell, Samuli M Rauhalammi, Giles Roditi, Christie Mccomb, Aleksandra Radjenovic, Paul WelshAbstract:Noninvasive quantification of myocardial fibrosis in end-stage renal disease is challenging. Gadolinium contrast agents previously used for cardiac magnetic resonance imaging (MRI) are contraindicated because of an association with nephrogenic systemic fibrosis. In other populations, increased myocardial native T1 times on cardiac MRI have been shown to be a surrogate marker of myocardial fibrosis. We applied this method to 33 incident Hemodialysis patients and 28 age- and sex-matched healthy volunteers who underwent MRI at 3.0T. Native T1 relaxation times and feature tracking–derived global longitudinal strain as potential markers of fibrosis were compared and associated with cardiac biomarkers. Left ventricular mass indices were higher in the Hemodialysis than the control group. Global, Septal and midseptal T1 times were all significantly higher in the Hemodialysis group (global T1 Hemodialysis 1171 ± 27 ms vs. 1154 ± 32 ms; septal T1 Hemodialysis 1184 ± 29 ms vs. 1163 ± 30 ms; and midseptal T1 Hemodialysis 1184 ± 34 ms vs. 1161 ± 29 ms). In the Hemodialysis group, T1 times correlated with left ventricular mass indices. Septal T1 times correlated with troponin and electrocardiogram-corrected QT interval. The peak global longitudinal strain was significantly reduced in the Hemodialysis group (Hemodialysis -17.7±5.3% vs. -21.8±6.2%). For Hemodialysis patients, the peak global longitudinal strain significantly correlated with left ventricular mass indices ( R = 0.426), and a trend was seen for correlation with galectin-3, a biomarker of cardiac fibrosis. Thus, cardiac tissue properties of Hemodialysis patients consistent with myocardial fibrosis can be determined noninvasively and associated with multiple structural and functional abnormalities.
Bruce F Culleton - One of the best experts on this subject based on the ideXlab platform.
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effect of frequent nocturnal Hemodialysis vs conventional Hemodialysis on left ventricular mass and quality of life a randomized controlled trial
JAMA, 2007Co-Authors: Bruce F Culleton, Michael Walsh, Marcello Tonelli, Scott Klarenbach, Garth Mortis, Narine Scottdouglas, Robert R Quinn, Sarah Donnelly, Matthias G Friedrich, Andreas KumarAbstract:ContextMorbidity and mortality rates in Hemodialysis patients remain excessive. Alterations in the delivery of dialysis may lead to improved patient outcomes.ObjectiveTo compare the effects of frequent nocturnal Hemodialysis vs conventional Hemodialysis on change in left ventricular mass and health-related quality of life over 6 months.Design, Setting, and ParticipantsA 2-group, parallel, randomized controlled trial conducted at 2 Canadian university centers between August 2004 and December 2006. A total of 52 patients undergoing Hemodialysis were recruited.InterventionParticipants were randomly assigned in a 1:1 ratio to receive nocturnal Hemodialysis 6 times weekly or conventional Hemodialysis 3 times weekly.Main Outcome MeasuresThe primary outcome was change in left ventricular mass, as measured by cardiovascular magnetic resonance imaging. The secondary outcomes were patient-reported quality of life, blood pressure, mineral metabolism, and use of medications.ResultsFrequent nocturnal Hemodialysis significantly improved the primary outcome (mean left ventricular mass difference between groups, 15.3 g, 95% confidence interval [CI], 1.0 to 29.6 g; P = .04). Frequent nocturnal Hemodialysis did not significantly improve quality of life (difference of change in EuroQol 5-D index from baseline, 0.05; 95% CI, −0.07 to 0.17; P = .43). However, frequent nocturnal Hemodialysis was associated with clinically and statistically significant improvements in selected kidney-specific domains of quality of life (P = .01 for effects of kidney disease and P = .02 for burden of kidney disease). Frequent nocturnal Hemodialysis was also associated with improvements in systolic blood pressure (P = .01 after adjustment) and mineral metabolism, including a reduction in or discontinuation of antihypertensive medications (16/26 patients in the nocturnal Hemodialysis group vs 3/25 patients in the conventional Hemodialysis group; P < .001) and oral phosphate binders (19/26 patients in the nocturnal Hemodialysis group vs 3/25 patients in the conventional dialysis group; P < .001). No benefit in anemia management was seen with nocturnal Hemodialysis.ConclusionThis preliminary study revealed that, compared with conventional Hemodialysis (3 times weekly), frequent nocturnal Hemodialysis improved left ventricular mass, reduced the need for blood pressure medications, improved some measures of mineral metabolism, and improved selected measures of quality of life.Trial Registrationisrctn.org Identifier: ISRCTN25858715
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effect of frequent nocturnal Hemodialysis vs conventional Hemodialysis on left ventricular mass and quality of life a randomized controlled trial
JAMA, 2007Co-Authors: Bruce F Culleton, Michael Walsh, Marcello Tonelli, Scott Klarenbach, Garth Mortis, Narine Scottdouglas, Robert R Quinn, Sarah Donnelly, Matthias G Friedrich, Andreas KumarAbstract:ContextMorbidity and mortality rates in Hemodialysis patients remain excessive. Alterations in the delivery of dialysis may lead to improved patient outcomes.ObjectiveTo compare the effects of frequent nocturnal Hemodialysis vs conventional Hemodialysis on change in left ventricular mass and health-related quality of life over 6 months.Design, Setting, and ParticipantsA 2-group, parallel, randomized controlled trial conducted at 2 Canadian university centers between August 2004 and December 2006. A total of 52 patients undergoing Hemodialysis were recruited.InterventionParticipants were randomly assigned in a 1:1 ratio to receive nocturnal Hemodialysis 6 times weekly or conventional Hemodialysis 3 times weekly.Main Outcome MeasuresThe primary outcome was change in left ventricular mass, as measured by cardiovascular magnetic resonance imaging. The secondary outcomes were patient-reported quality of life, blood pressure, mineral metabolism, and use of medications.ResultsFrequent nocturnal Hemodialysis significantly improved the primary outcome (mean left ventricular mass difference between groups, 15.3 g, 95% confidence interval [CI], 1.0 to 29.6 g; P = .04). Frequent nocturnal Hemodialysis did not significantly improve quality of life (difference of change in EuroQol 5-D index from baseline, 0.05; 95% CI, −0.07 to 0.17; P = .43). However, frequent nocturnal Hemodialysis was associated with clinically and statistically significant improvements in selected kidney-specific domains of quality of life (P = .01 for effects of kidney disease and P = .02 for burden of kidney disease). Frequent nocturnal Hemodialysis was also associated with improvements in systolic blood pressure (P = .01 after adjustment) and mineral metabolism, including a reduction in or discontinuation of antihypertensive medications (16/26 patients in the nocturnal Hemodialysis group vs 3/25 patients in the conventional Hemodialysis group; P < .001) and oral phosphate binders (19/26 patients in the nocturnal Hemodialysis group vs 3/25 patients in the conventional dialysis group; P < .001). No benefit in anemia management was seen with nocturnal Hemodialysis.ConclusionThis preliminary study revealed that, compared with conventional Hemodialysis (3 times weekly), frequent nocturnal Hemodialysis improved left ventricular mass, reduced the need for blood pressure medications, improved some measures of mineral metabolism, and improved selected measures of quality of life.Trial Registrationisrctn.org Identifier: ISRCTN25858715
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a systematic review of the effect of nocturnal Hemodialysis on blood pressure left ventricular hypertrophy anemia mineral metabolism and health related quality of life
Kidney International, 2005Co-Authors: Michael Walsh, Marcello Tonelli, Bruce F Culleton, Braden J MannsAbstract:A systematic review of the effect of nocturnal Hemodialysis on blood pressure, left ventricular hypertrophy, anemia, mineral metabolism, and health-related quality of life. Background Nocturnal Hemodialysis is a novel form of dialysis where patients perform dialysis 6 nights per week while they sleep. Multiple publications report significant improvements in selected clinical outcomes, although the strength of these results is limited by shortcomings in study design. A systematic review of the current available literature was undertaken to examine the effect of nocturnal Hemodialysis on key health outcomes. Methods An inclusive search of medical databases was undertaken to identify all nocturnal Hemodialysis studies. These results were manually reviewed for relevance to nocturnal Hemodialysis and its impact on the following predefined health outcomes: blood pressure control, left ventricular hypertrophy, anemia, mineral metabolism, and health related quality of life. Case reports, short-term studies ( Results Of the initial 270 studies identified, only 14 met inclusion/exclusion criteria. No studies examining the impact of nocturnal Hemodialysis on mortality were identified. All studies reported improved blood pressure control after conversion to nocturnal Hemodialysis. Data regarding the other health outcomes of interest revealed mixed results. Conclusion Nocturnal Hemodialysis is a potential alternative to conventional intermittent Hemodialysis. Before significant resources are invested in initiating nocturnal Hemodialysis programs, further data on mortality and cardiovascular morbidity, preferably from randomized clinical trials, are required.
