The Experts below are selected from a list of 3786 Experts worldwide ranked by ideXlab platform
Shane Darke - One of the best experts on this subject based on the ideXlab platform.
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The long-term impact of post traumatic stress disorder on recovery from Heroin Dependence.
Journal of substance abuse treatment, 2018Co-Authors: Katherine L. Mills, Shane Darke, Joanne Ross, Christina Marel, Tim Slade, Maree TeessonAbstract:Abstract The high prevalence of post traumatic stress disorder (PTSD) among people with Heroin Dependence and its impact on short term outcomes has been well established. The impact of PTSD on long-term recovery is, however, unknown. This paper examines the impact of current and lifetime PTSD on long-term recovery from Heroin Dependence among participants who took part in the 11-year follow-up of the Australian Treatment Outcome Study (ATOS), a prospective naturalistic longitudinal study of 615 people with Heroin Dependence recruited from Sydney, Australia, in 2001–2002. Seventy-one percent of the cohort (n = 431) were re-interviewed 11-years post study entry. Outcomes examined included Heroin and other drug use, Dependence, general physical and mental health, depression, PTSD, employment, and the incidence of trauma exposure, overdose, imprisonment, and attempted suicide over the 11- year follow-up. Despite having a poorer profile at baseline, individuals with current PTSD or a history of PTSD at baseline demonstrated similar levels of improvement to those without a history of PTSD in all outcome domains across the 11-year follow-up, PTSD was associated with consistently higher levels of major depression, and attempted suicide, subsequent trauma exposure, and poorer occupational functioning across the 11-year follow-up. These findings highlight the importance of interventions aimed at occupational rehabilitation, reducing the likelihood of retraumatisation, and addressing PTSD and associated comorbidities among people with Heroin Dependence.
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Developmental trajectories to Heroin Dependence: Theoretical and clinical issues
Journal of Applied Social Psychology, 2017Co-Authors: Shane Darke, Michelle Torok, Joanne RossAbstract:We have built up a great deal of insight into the early developmental trajectories that lead to Heroin use. These cluster under five domains: social disadvantage, parental drug use/psychopathology, childhood abuse and neglect, early onset psychopathology and antisocial behaviors, and a developmental sequence of drug onsets. While not all Heroin users have these risk factors, the broad clinical picture shows these early correlates to be the predominant presentation. We discuss each of the early psychosocial correlates of Heroin Dependence, as well as possible early interventions. Given the chronicity of Heroin Dependence, interventions to prevent Heroin use emerging would reduce the considerable burden of disease associated with the disorder.
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the impact of post traumatic stress disorder on treatment outcomes for Heroin Dependence
Addiction, 2007Co-Authors: Katherine L. Mills, Joanne Ross, Maree Teesson, Shane DarkeAbstract:Aims To examine the impact of post-traumatic stress disorder (PTSD) on 2-year treatment outcomes for Heroin Dependence. Design Prospective longitudinal study. Participants Data were obtained from a predominantly treatment seeking sample of 615 dependent Heroin users who were followed-up at 3, 12 and 24 months (follow-up rates: 89%, 81% and 76%, respectively). Measurements Outcomes examined include treatment retention and exposure, substance use, general physical and mental health and employment. Findings Despite improvements in substance use, PTSD was associated with continued physical (β− 1.69, SE 0.61, P < 0.01) and mental disability (β− 2.07, SE 0.66, P < 0.01), and reduced occupational functioning (OR 0.67, 95% CI: 0.48–0.93) throughout the 2-year follow-up. Conclusions Although conventional treatment services are successful in producing improvements in substance use and associated disability, the disability associated with PTSD remains. An intervention targeting both Heroin Dependence and PTSD may help to improve the outcomes of those with PTSD.
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post traumatic stress disorder among people with Heroin Dependence in the australian treatment outcome study atos prevalence and correlates
Drug and Alcohol Dependence, 2005Co-Authors: Katherine L. Mills, Joanne Ross, Maree Teesson, Michael T Lynskey, Shane DarkeAbstract:This study documents the prevalence and correlates of post-traumatic stress disorder (PTSD) among Australian individuals with Heroin Dependence. Data was obtained from a cohort of 615 people dependent on Heroin, 535 entering treatment for their Heroin Dependence and 80 individuals not in treatment. Trauma exposure (92%) and lifetime PTSD (41%) were highly prevalent. PTSD was prevalent across all treatment modalities, most commonly residential rehabilitation (52%) followed by maintenance therapies (42%), and detoxification (37%). The lowest prevalence was reported among those not in treatment (30%). Although men and women were equally likely to have experienced trauma (93% vs. 89%), women were more likely to develop lifetime PTSD (61% vs. 37%). For the large majority of those with PTSD, the condition was chronic (84%), with symptoms continuing for an average of 9.5 years. Those with PTSD had more extensive polydrug use histories, poorer general physical and mental health, and more extensive health service utilisation. It is concluded that PTSD is highly prevalent among individuals with Heroin Dependence, presenting a significant challenge to treatment providers.
Katherine L. Mills - One of the best experts on this subject based on the ideXlab platform.
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The long-term impact of post traumatic stress disorder on recovery from Heroin Dependence.
Journal of substance abuse treatment, 2018Co-Authors: Katherine L. Mills, Shane Darke, Joanne Ross, Christina Marel, Tim Slade, Maree TeessonAbstract:Abstract The high prevalence of post traumatic stress disorder (PTSD) among people with Heroin Dependence and its impact on short term outcomes has been well established. The impact of PTSD on long-term recovery is, however, unknown. This paper examines the impact of current and lifetime PTSD on long-term recovery from Heroin Dependence among participants who took part in the 11-year follow-up of the Australian Treatment Outcome Study (ATOS), a prospective naturalistic longitudinal study of 615 people with Heroin Dependence recruited from Sydney, Australia, in 2001–2002. Seventy-one percent of the cohort (n = 431) were re-interviewed 11-years post study entry. Outcomes examined included Heroin and other drug use, Dependence, general physical and mental health, depression, PTSD, employment, and the incidence of trauma exposure, overdose, imprisonment, and attempted suicide over the 11- year follow-up. Despite having a poorer profile at baseline, individuals with current PTSD or a history of PTSD at baseline demonstrated similar levels of improvement to those without a history of PTSD in all outcome domains across the 11-year follow-up, PTSD was associated with consistently higher levels of major depression, and attempted suicide, subsequent trauma exposure, and poorer occupational functioning across the 11-year follow-up. These findings highlight the importance of interventions aimed at occupational rehabilitation, reducing the likelihood of retraumatisation, and addressing PTSD and associated comorbidities among people with Heroin Dependence.
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the impact of post traumatic stress disorder on treatment outcomes for Heroin Dependence
Addiction, 2007Co-Authors: Katherine L. Mills, Joanne Ross, Maree Teesson, Shane DarkeAbstract:Aims To examine the impact of post-traumatic stress disorder (PTSD) on 2-year treatment outcomes for Heroin Dependence. Design Prospective longitudinal study. Participants Data were obtained from a predominantly treatment seeking sample of 615 dependent Heroin users who were followed-up at 3, 12 and 24 months (follow-up rates: 89%, 81% and 76%, respectively). Measurements Outcomes examined include treatment retention and exposure, substance use, general physical and mental health and employment. Findings Despite improvements in substance use, PTSD was associated with continued physical (β− 1.69, SE 0.61, P < 0.01) and mental disability (β− 2.07, SE 0.66, P < 0.01), and reduced occupational functioning (OR 0.67, 95% CI: 0.48–0.93) throughout the 2-year follow-up. Conclusions Although conventional treatment services are successful in producing improvements in substance use and associated disability, the disability associated with PTSD remains. An intervention targeting both Heroin Dependence and PTSD may help to improve the outcomes of those with PTSD.
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post traumatic stress disorder among people with Heroin Dependence in the australian treatment outcome study atos prevalence and correlates
Drug and Alcohol Dependence, 2005Co-Authors: Katherine L. Mills, Joanne Ross, Maree Teesson, Michael T Lynskey, Shane DarkeAbstract:This study documents the prevalence and correlates of post-traumatic stress disorder (PTSD) among Australian individuals with Heroin Dependence. Data was obtained from a cohort of 615 people dependent on Heroin, 535 entering treatment for their Heroin Dependence and 80 individuals not in treatment. Trauma exposure (92%) and lifetime PTSD (41%) were highly prevalent. PTSD was prevalent across all treatment modalities, most commonly residential rehabilitation (52%) followed by maintenance therapies (42%), and detoxification (37%). The lowest prevalence was reported among those not in treatment (30%). Although men and women were equally likely to have experienced trauma (93% vs. 89%), women were more likely to develop lifetime PTSD (61% vs. 37%). For the large majority of those with PTSD, the condition was chronic (84%), with symptoms continuing for an average of 9.5 years. Those with PTSD had more extensive polydrug use histories, poorer general physical and mental health, and more extensive health service utilisation. It is concluded that PTSD is highly prevalent among individuals with Heroin Dependence, presenting a significant challenge to treatment providers.
Maree Teesson - One of the best experts on this subject based on the ideXlab platform.
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The long-term impact of post traumatic stress disorder on recovery from Heroin Dependence.
Journal of substance abuse treatment, 2018Co-Authors: Katherine L. Mills, Shane Darke, Joanne Ross, Christina Marel, Tim Slade, Maree TeessonAbstract:Abstract The high prevalence of post traumatic stress disorder (PTSD) among people with Heroin Dependence and its impact on short term outcomes has been well established. The impact of PTSD on long-term recovery is, however, unknown. This paper examines the impact of current and lifetime PTSD on long-term recovery from Heroin Dependence among participants who took part in the 11-year follow-up of the Australian Treatment Outcome Study (ATOS), a prospective naturalistic longitudinal study of 615 people with Heroin Dependence recruited from Sydney, Australia, in 2001–2002. Seventy-one percent of the cohort (n = 431) were re-interviewed 11-years post study entry. Outcomes examined included Heroin and other drug use, Dependence, general physical and mental health, depression, PTSD, employment, and the incidence of trauma exposure, overdose, imprisonment, and attempted suicide over the 11- year follow-up. Despite having a poorer profile at baseline, individuals with current PTSD or a history of PTSD at baseline demonstrated similar levels of improvement to those without a history of PTSD in all outcome domains across the 11-year follow-up, PTSD was associated with consistently higher levels of major depression, and attempted suicide, subsequent trauma exposure, and poorer occupational functioning across the 11-year follow-up. These findings highlight the importance of interventions aimed at occupational rehabilitation, reducing the likelihood of retraumatisation, and addressing PTSD and associated comorbidities among people with Heroin Dependence.
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the impact of post traumatic stress disorder on treatment outcomes for Heroin Dependence
Addiction, 2007Co-Authors: Katherine L. Mills, Joanne Ross, Maree Teesson, Shane DarkeAbstract:Aims To examine the impact of post-traumatic stress disorder (PTSD) on 2-year treatment outcomes for Heroin Dependence. Design Prospective longitudinal study. Participants Data were obtained from a predominantly treatment seeking sample of 615 dependent Heroin users who were followed-up at 3, 12 and 24 months (follow-up rates: 89%, 81% and 76%, respectively). Measurements Outcomes examined include treatment retention and exposure, substance use, general physical and mental health and employment. Findings Despite improvements in substance use, PTSD was associated with continued physical (β− 1.69, SE 0.61, P < 0.01) and mental disability (β− 2.07, SE 0.66, P < 0.01), and reduced occupational functioning (OR 0.67, 95% CI: 0.48–0.93) throughout the 2-year follow-up. Conclusions Although conventional treatment services are successful in producing improvements in substance use and associated disability, the disability associated with PTSD remains. An intervention targeting both Heroin Dependence and PTSD may help to improve the outcomes of those with PTSD.
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post traumatic stress disorder among people with Heroin Dependence in the australian treatment outcome study atos prevalence and correlates
Drug and Alcohol Dependence, 2005Co-Authors: Katherine L. Mills, Joanne Ross, Maree Teesson, Michael T Lynskey, Shane DarkeAbstract:This study documents the prevalence and correlates of post-traumatic stress disorder (PTSD) among Australian individuals with Heroin Dependence. Data was obtained from a cohort of 615 people dependent on Heroin, 535 entering treatment for their Heroin Dependence and 80 individuals not in treatment. Trauma exposure (92%) and lifetime PTSD (41%) were highly prevalent. PTSD was prevalent across all treatment modalities, most commonly residential rehabilitation (52%) followed by maintenance therapies (42%), and detoxification (37%). The lowest prevalence was reported among those not in treatment (30%). Although men and women were equally likely to have experienced trauma (93% vs. 89%), women were more likely to develop lifetime PTSD (61% vs. 37%). For the large majority of those with PTSD, the condition was chronic (84%), with symptoms continuing for an average of 9.5 years. Those with PTSD had more extensive polydrug use histories, poorer general physical and mental health, and more extensive health service utilisation. It is concluded that PTSD is highly prevalent among individuals with Heroin Dependence, presenting a significant challenge to treatment providers.
Alison Ritter - One of the best experts on this subject based on the ideXlab platform.
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A randomised trial of the cost effectiveness of Buprenorphine as an alternative to methadone maintenance treatment for Heroin Dependence in a primary care setting
PharmacoEconomics, 2005Co-Authors: Anthony Harris, Elena Gospodarevskaya, Alison RitterAbstract:Background and aim: Buprenorphine offers an alternative to methadone in the treatment of Heroin Dependence, and has the advantage of allowing alternate-day dosing. This study is the first to examine the cost effectiveness of buprenorphine as maintenance treatment for Heroin Dependence in a primary care setting using economic and clinical data collected within a randomised trial.
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laam maintenance vs methadone maintenance for Heroin Dependence
Cochrane Database of Systematic Reviews, 2002Co-Authors: Nicolas Clark, Nicholas Lintzeris, Alan Gijsbers, Greg Whelan, Adrian Dunlop, Alison Ritter, Walter LingAbstract:Objective: To compare the efficacy and acceptability of LAAM maintenance with methadone maintenance in the treatment of Heroin Dependence. Opiate drugs are used to help people reduce their Dependence on Heroin (an opiate drug). Methadone needs daily doses, but the effects do not last 24 hours for many people. A dose of LAAM (levomethadyl acetate hydrochloride) works for two or three days. LAAM is not as widely available internationally as methadone, and may be withdrawn from the market because of concerns about life-threatening effects on the heart. The review found that LAAM is more effective than methadone at reducing Heroin Dependence, but there was not enough evidence from trials to draw conclusions about safety.
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The Cochrane Library - LAAM maintenance vs methadone maintenance for Heroin Dependence.
The Cochrane database of systematic reviews, 2002Co-Authors: Nicolas Clark, Nicholas Lintzeris, Alan Gijsbers, Greg Whelan, Adrian Dunlop, Alison Ritter, Walter LingAbstract:Objective: To compare the efficacy and acceptability of LAAM maintenance with methadone maintenance in the treatment of Heroin Dependence. Opiate drugs are used to help people reduce their Dependence on Heroin (an opiate drug). Methadone needs daily doses, but the effects do not last 24 hours for many people. A dose of LAAM (levomethadyl acetate hydrochloride) works for two or three days. LAAM is not as widely available internationally as methadone, and may be withdrawn from the market because of concerns about life-threatening effects on the heart. The review found that LAAM is more effective than methadone at reducing Heroin Dependence, but there was not enough evidence from trials to draw conclusions about safety.
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Naltrexone in the Treatment of Heroin Dependence: Relationship with Depression and Risk of Overdose:
The Australian and New Zealand journal of psychiatry, 2002Co-Authors: Alison RitterAbstract:Objective: This article examines the use of naltrexone in the treatment of Heroin Dependence. The relationship between naltrexone and depression as well as risk of overdose is examined.Method: The existing literature is reviewed along with recent interim data from clinical trials underway in Victoria.Results: Naltrexone is a recent addition to treatment for Heroin Dependence in Australia. The relationship between depression and naltrexone has been examined in previous literature. Underlying rates of depression in Heroin users are high and treatment may resolve or exacerbate depression. Research to date demonstrates that the addition of naltrexone does not necessarily increase depression in patients. The risk of non-fatal Heroin overdose is significantly elevated after naltrexone treatment as a result of reduced tolerance. Data from clinical trials underway in Victoria demonstrate a significantly elevated rate of non-fatal overdose in naltrexone patients compared to those in substitution maintenance treatm...
Joanne Ross - One of the best experts on this subject based on the ideXlab platform.
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The long-term impact of post traumatic stress disorder on recovery from Heroin Dependence.
Journal of substance abuse treatment, 2018Co-Authors: Katherine L. Mills, Shane Darke, Joanne Ross, Christina Marel, Tim Slade, Maree TeessonAbstract:Abstract The high prevalence of post traumatic stress disorder (PTSD) among people with Heroin Dependence and its impact on short term outcomes has been well established. The impact of PTSD on long-term recovery is, however, unknown. This paper examines the impact of current and lifetime PTSD on long-term recovery from Heroin Dependence among participants who took part in the 11-year follow-up of the Australian Treatment Outcome Study (ATOS), a prospective naturalistic longitudinal study of 615 people with Heroin Dependence recruited from Sydney, Australia, in 2001–2002. Seventy-one percent of the cohort (n = 431) were re-interviewed 11-years post study entry. Outcomes examined included Heroin and other drug use, Dependence, general physical and mental health, depression, PTSD, employment, and the incidence of trauma exposure, overdose, imprisonment, and attempted suicide over the 11- year follow-up. Despite having a poorer profile at baseline, individuals with current PTSD or a history of PTSD at baseline demonstrated similar levels of improvement to those without a history of PTSD in all outcome domains across the 11-year follow-up, PTSD was associated with consistently higher levels of major depression, and attempted suicide, subsequent trauma exposure, and poorer occupational functioning across the 11-year follow-up. These findings highlight the importance of interventions aimed at occupational rehabilitation, reducing the likelihood of retraumatisation, and addressing PTSD and associated comorbidities among people with Heroin Dependence.
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Developmental trajectories to Heroin Dependence: Theoretical and clinical issues
Journal of Applied Social Psychology, 2017Co-Authors: Shane Darke, Michelle Torok, Joanne RossAbstract:We have built up a great deal of insight into the early developmental trajectories that lead to Heroin use. These cluster under five domains: social disadvantage, parental drug use/psychopathology, childhood abuse and neglect, early onset psychopathology and antisocial behaviors, and a developmental sequence of drug onsets. While not all Heroin users have these risk factors, the broad clinical picture shows these early correlates to be the predominant presentation. We discuss each of the early psychosocial correlates of Heroin Dependence, as well as possible early interventions. Given the chronicity of Heroin Dependence, interventions to prevent Heroin use emerging would reduce the considerable burden of disease associated with the disorder.
-
the impact of post traumatic stress disorder on treatment outcomes for Heroin Dependence
Addiction, 2007Co-Authors: Katherine L. Mills, Joanne Ross, Maree Teesson, Shane DarkeAbstract:Aims To examine the impact of post-traumatic stress disorder (PTSD) on 2-year treatment outcomes for Heroin Dependence. Design Prospective longitudinal study. Participants Data were obtained from a predominantly treatment seeking sample of 615 dependent Heroin users who were followed-up at 3, 12 and 24 months (follow-up rates: 89%, 81% and 76%, respectively). Measurements Outcomes examined include treatment retention and exposure, substance use, general physical and mental health and employment. Findings Despite improvements in substance use, PTSD was associated with continued physical (β− 1.69, SE 0.61, P < 0.01) and mental disability (β− 2.07, SE 0.66, P < 0.01), and reduced occupational functioning (OR 0.67, 95% CI: 0.48–0.93) throughout the 2-year follow-up. Conclusions Although conventional treatment services are successful in producing improvements in substance use and associated disability, the disability associated with PTSD remains. An intervention targeting both Heroin Dependence and PTSD may help to improve the outcomes of those with PTSD.
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post traumatic stress disorder among people with Heroin Dependence in the australian treatment outcome study atos prevalence and correlates
Drug and Alcohol Dependence, 2005Co-Authors: Katherine L. Mills, Joanne Ross, Maree Teesson, Michael T Lynskey, Shane DarkeAbstract:This study documents the prevalence and correlates of post-traumatic stress disorder (PTSD) among Australian individuals with Heroin Dependence. Data was obtained from a cohort of 615 people dependent on Heroin, 535 entering treatment for their Heroin Dependence and 80 individuals not in treatment. Trauma exposure (92%) and lifetime PTSD (41%) were highly prevalent. PTSD was prevalent across all treatment modalities, most commonly residential rehabilitation (52%) followed by maintenance therapies (42%), and detoxification (37%). The lowest prevalence was reported among those not in treatment (30%). Although men and women were equally likely to have experienced trauma (93% vs. 89%), women were more likely to develop lifetime PTSD (61% vs. 37%). For the large majority of those with PTSD, the condition was chronic (84%), with symptoms continuing for an average of 9.5 years. Those with PTSD had more extensive polydrug use histories, poorer general physical and mental health, and more extensive health service utilisation. It is concluded that PTSD is highly prevalent among individuals with Heroin Dependence, presenting a significant challenge to treatment providers.