The Experts below are selected from a list of 1308 Experts worldwide ranked by ideXlab platform
Eul Kgun Yum - One of the best experts on this subject based on the ideXlab platform.
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Copper‐ and Ligand‐Free Heteroannulation of o‐Halohydroxypyridine with Terminal Alkynes Using Pd/C Catalyst: One‐Pot Synthesis of 2‐Substituted Furopyridines and Their Functionalization.
ChemInform, 2015Co-Authors: Hee Jung Park, Eul Kgun Yum, Ji-eun Kim, Younghoon Kim, Chang-woo HanAbstract:The double functionalization can be achieved through Heteroannulation followed by bromination and Suzuki/Heck reactions (X), (XII).
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copper and ligand free Heteroannulation of o halohydroxypyridine with terminal alkynes using pd c catalyst one pot synthesis of 2 substituted furopyridines and their functionalization
ChemInform, 2015Co-Authors: Hee Jung Park, Eul Kgun Yum, Ji-eun Kim, Younghoon Kim, Chang-woo HanAbstract:The double functionalization can be achieved through Heteroannulation followed by bromination and Suzuki/Heck reactions (X), (XII).
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Copper- and Ligand-free Heteroannulation of o-Halohydroxypyridine with Terminal Alkynes Using Pd/C Catalyst: One-Pot Synthesis of 2-Substituted Furopyridines and their Functionalization
Bulletin of the Korean Chemical Society, 2015Co-Authors: Hee Jung Park, Eul Kgun Yum, Ji-eun Kim, Younghoon Kim, Chang-woo HanAbstract:Three types of isomeric 2-substituted furo[3,2-b]pyridine, furo[2,3-b]pyridine and furo[3,2-c]pyridine were prepared using Pd/C-catalyzed Heteroannulation of o-halopyridinols and terminal alkynes under copper- and ligand-free conditions. We also demonstrated that double functionalization yielding 2,3-disubstituted furopyridines could be achieved through Heteroannulation followed by bromination and Suzuki/Heck reactions. In addition, the use of recoverable Pd/C in the absence of a cocatalyst and ligand can aid in the development of greener chemical processes.
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Synthesis of 2-substituted indoles by palladium-catalyzed Heteroannulation with Pd–NaY zeolite catalysts
Tetrahedron Letters, 2004Co-Authors: Ki Bum Hong, Chul Wee Lee, Eul Kgun YumAbstract:Abstract Various 2-substituted indoles were prepared by Heteroannulation of o -iodoanilines and terminal alkynes in a one-pot reaction with a Pd(II)–NaY zeolite catalyst. The product formation largely depended on the solvent, base, and reaction temperature. The recycled catalyst showed good reusability in the Heteroannulation reaction.
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Synthesis of 1,2,3-trisubstituted pyrrolo[3,2-c]quinolines via palladium-catalyzed Heteroannulation with internal alkynes
Tetrahedron Letters, 1999Co-Authors: Seung Kyu Kang, Sang Sun Park, Sungsoo S. Kim, Joong-kwon Choi, Eul Kgun YumAbstract:Abstract Various 1,2,3-trisubstituted pyrrolo[3,2- c ]quinolines were synthesized by palladium-catalyzed Heteroannulation of 4-amino-3-iodoquinoline derivatives and internal alkynes. The 1,2,3-trisubstituted pyrrolo[3,2- c ]quinolines could be further transformed by desilylation, debenzylation, or substitution.
Nicola Collar - One of the best experts on this subject based on the ideXlab platform.
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Synthesis of 6,7-disubstituted-5H-pyrrolo[2,3-b]pyrazines via palladium-catalyzed Heteroannulation
Tetrahedron Letters, 2005Co-Authors: Corey R. Hopkins, Nicola CollarAbstract:A concise and efficient method for the preparation of 6,7-disubstituted-5H-pyrrolo[2,3-b]pyrazines via a palladium-catalyzed Heteroannulation is reported. Both conventional and microwave heating were used to perform the reactions, with the latter showing dramatically improved results.
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An improved method for the synthesis of 6-substituted-5H-pyrrolo[2,3-b] pyrazines via palladium-catalyzed Heteroannulation using microwave heating
Tetrahedron Letters, 2004Co-Authors: Corey R. Hopkins, Nicola CollarAbstract:We herein report an improved synthesis of 6-substituted-5H-pyrrolo[2,3-b]pyrazines utilizing microwave heating. The reaction is a palladium-catalyzed Heteroannulation process followed by deprotection to yield the desired substrates in good yield.
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6-Substituted-5H-pyrrolo[2,3-b]pyrazines via palladium-catalyzed Heteroannulation from N-(3-chloropyrazin-2-yl)-methanesulfonamide and alkynes
Tetrahedron Letters, 2004Co-Authors: Corey R. Hopkins, Nicola CollarAbstract:We herein report the efficient and convenient synthesis of 6-substituted-5H-pyrrolo[2,3-b]pyrazines. The reaction is a palladium-catalyzed Heteroannulation process followed by deprotection to yield the desired pyrrolo[2,3-b]pyrazine substrates. The reaction starts with readily accessible N-(3-chloropyrazin-2-yl)-methanesulfonamide and commercially available terminal alkynes and works with aryl- and alkylalkynes.
Rajagopal Nagarajan - One of the best experts on this subject based on the ideXlab platform.
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Copper-catalyzed Heteroannulation: a simple route to the synthesis of pyrrolo[2,3-b]carbazole and pyrrolo[2,3-b]quinoline derivatives
Tetrahedron Letters, 2015Co-Authors: K. S. Prakash, Rajagopal NagarajanAbstract:Abstract A simple and efficient method for the synthesis of biologically important pyrrolo[2,3-b]carbazoles and pyrrolo[2,3-b]quinolines is described. This involves the reaction of corresponding carbazole or quinoline-1,2-haloaldehyde with isocyanoacetate via copper catalyzed Heteroannulation in good yields.
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Synthesis of solid state fluorescent quino[2,3-b]carbazoles via copper(II) triflate-catalyzed Heteroannulation: application to detection of TNT
Tetrahedron, 2013Co-Authors: K. S. Prakash, Rajagopal NagarajanAbstract:Abstract New analogues of solid state fluorescent quino[2,3-b]carbazoles have been synthesized from Heteroannulation of quinoline alkynylaldehyde and indole. Their preliminary photophysical properties are studied and application as chemosensory material for detection of trinitrotoluene is explored.
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An efficient synthesis of indol-3-yl benzonaphthyridines via copper(II) triflate-catalyzed Heteroannulation
Tetrahedron Letters, 2013Co-Authors: K. S. Prakash, Rajagopal NagarajanAbstract:Abstract An efficient and convenient method for the synthesis of indol-3-yl benzo[b][1,6]- and benzo[c][2,7]naphthyridines via copper(II) triflate-catalyzed Heteroannulation is reported. This method gives new analogues of indole containing benzonaphthyridines from easily accessible starting materials. This reaction proceeds under mild conditions.
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a general method for the synthesis of 5h benzo b carbazolo 2 3 b and indolo 2 3 b carbazole derivatives via copper ii triflate catalyzed Heteroannulation
ChemInform, 2012Co-Authors: K. S. Prakash, Rajagopal NagarajanAbstract:A wide range of title compounds via is constructed Heteroannulation which is best catalyzed by Cu(OTf)2.
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A General Method for the Synthesis of 5H‐Benzo[b]‐, Carbazolo[2,3‐b]‐ and Indolo[2,3‐b]carbazole Derivatives via Copper(II) Triflate‐Catalyzed Heteroannulation.
ChemInform, 2012Co-Authors: K. S. Prakash, Rajagopal NagarajanAbstract:A wide range of title compounds via is constructed Heteroannulation which is best catalyzed by Cu(OTf)2.
Corey R. Hopkins - One of the best experts on this subject based on the ideXlab platform.
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Synthesis of 6,7-disubstituted-5H-pyrrolo[2,3-b]pyrazines via palladium-catalyzed Heteroannulation
Tetrahedron Letters, 2005Co-Authors: Corey R. Hopkins, Nicola CollarAbstract:A concise and efficient method for the preparation of 6,7-disubstituted-5H-pyrrolo[2,3-b]pyrazines via a palladium-catalyzed Heteroannulation is reported. Both conventional and microwave heating were used to perform the reactions, with the latter showing dramatically improved results.
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An improved method for the synthesis of 6-substituted-5H-pyrrolo[2,3-b] pyrazines via palladium-catalyzed Heteroannulation using microwave heating
Tetrahedron Letters, 2004Co-Authors: Corey R. Hopkins, Nicola CollarAbstract:We herein report an improved synthesis of 6-substituted-5H-pyrrolo[2,3-b]pyrazines utilizing microwave heating. The reaction is a palladium-catalyzed Heteroannulation process followed by deprotection to yield the desired substrates in good yield.
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6-Substituted-5H-pyrrolo[2,3-b]pyrazines via palladium-catalyzed Heteroannulation from N-(3-chloropyrazin-2-yl)-methanesulfonamide and alkynes
Tetrahedron Letters, 2004Co-Authors: Corey R. Hopkins, Nicola CollarAbstract:We herein report the efficient and convenient synthesis of 6-substituted-5H-pyrrolo[2,3-b]pyrazines. The reaction is a palladium-catalyzed Heteroannulation process followed by deprotection to yield the desired pyrrolo[2,3-b]pyrazine substrates. The reaction starts with readily accessible N-(3-chloropyrazin-2-yl)-methanesulfonamide and commercially available terminal alkynes and works with aryl- and alkylalkynes.
K. S. Prakash - One of the best experts on this subject based on the ideXlab platform.
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Copper-catalyzed Heteroannulation: a simple route to the synthesis of pyrrolo[2,3-b]carbazole and pyrrolo[2,3-b]quinoline derivatives
Tetrahedron Letters, 2015Co-Authors: K. S. Prakash, Rajagopal NagarajanAbstract:Abstract A simple and efficient method for the synthesis of biologically important pyrrolo[2,3-b]carbazoles and pyrrolo[2,3-b]quinolines is described. This involves the reaction of corresponding carbazole or quinoline-1,2-haloaldehyde with isocyanoacetate via copper catalyzed Heteroannulation in good yields.
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Synthesis of solid state fluorescent quino[2,3-b]carbazoles via copper(II) triflate-catalyzed Heteroannulation: application to detection of TNT
Tetrahedron, 2013Co-Authors: K. S. Prakash, Rajagopal NagarajanAbstract:Abstract New analogues of solid state fluorescent quino[2,3-b]carbazoles have been synthesized from Heteroannulation of quinoline alkynylaldehyde and indole. Their preliminary photophysical properties are studied and application as chemosensory material for detection of trinitrotoluene is explored.
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An efficient synthesis of indol-3-yl benzonaphthyridines via copper(II) triflate-catalyzed Heteroannulation
Tetrahedron Letters, 2013Co-Authors: K. S. Prakash, Rajagopal NagarajanAbstract:Abstract An efficient and convenient method for the synthesis of indol-3-yl benzo[b][1,6]- and benzo[c][2,7]naphthyridines via copper(II) triflate-catalyzed Heteroannulation is reported. This method gives new analogues of indole containing benzonaphthyridines from easily accessible starting materials. This reaction proceeds under mild conditions.
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a general method for the synthesis of 5h benzo b carbazolo 2 3 b and indolo 2 3 b carbazole derivatives via copper ii triflate catalyzed Heteroannulation
ChemInform, 2012Co-Authors: K. S. Prakash, Rajagopal NagarajanAbstract:A wide range of title compounds via is constructed Heteroannulation which is best catalyzed by Cu(OTf)2.
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A General Method for the Synthesis of 5H‐Benzo[b]‐, Carbazolo[2,3‐b]‐ and Indolo[2,3‐b]carbazole Derivatives via Copper(II) Triflate‐Catalyzed Heteroannulation.
ChemInform, 2012Co-Authors: K. S. Prakash, Rajagopal NagarajanAbstract:A wide range of title compounds via is constructed Heteroannulation which is best catalyzed by Cu(OTf)2.