The Experts below are selected from a list of 708 Experts worldwide ranked by ideXlab platform

Charles D. Spielberger - One of the best experts on this subject based on the ideXlab platform.

  • Errors in Shooting Judgment and Performance by Law Enforcement Personnel During a Stressful Training Scenario
    2004
    Co-Authors: James L. Meyerhoff, William P. Norris, George A. Saviolakis, Terry Wollert, Bob Burge, Valerie Atkins, Charles D. Spielberger
    Abstract:

    Abstract : Police trainees who were ready to graduate from the Federal Law Enforcement Training, Center (FLETC) volunteered to participated in an exercise designed to evaluate their survivability. In a highly stressful interactive scenario, which included a Hostage Situation during a staged domestic dispute, performance was evaluated for a range of responses, including: weapon malfunction, shooting judgement and accuracy, communications, and emotional reactions. Nineteen percent of subjects shot the Hostage, a failure rate that falls in the reported range of friendly fire casualties in military combat. The Spielberger Trait Anger Scale showed an association with shot placement and performance during the gunfight, as well as with overall performance scores.

  • Evaluating Performance of Law Enforcement Personnel during a Stressful Training Scenario
    Annals of the New York Academy of Sciences, 2004
    Co-Authors: James L. Meyerhoff, William P. Norris, George A. Saviolakis, Terry Wollert, Bob Burge, Valerie Atkins, Charles D. Spielberger
    Abstract:

    Police trainees who were ready to graduate from the Federal Law Enforcement Training Center (FLETC) volunteered to participate in an exercise designed to evaluate their survivability. In a highly stressful interactive scenario, which included a Hostage Situation, performance was evaluated for a range of responses, including: shooting judgment and accuracy, communications, and coping with a weapon malfunction. Nineteen percent of subjects shot the Hostage, a failure rate that falls in the reported range of friendly fire casualties in military combat. The Spielberger Trait Anger Scale showed an association with shot placement and performance during the gunfight as well as with overall performance scores.

James L. Meyerhoff - One of the best experts on this subject based on the ideXlab platform.

  • Errors in Shooting Judgment and Performance by Law Enforcement Personnel During a Stressful Training Scenario
    2004
    Co-Authors: James L. Meyerhoff, William P. Norris, George A. Saviolakis, Terry Wollert, Bob Burge, Valerie Atkins, Charles D. Spielberger
    Abstract:

    Abstract : Police trainees who were ready to graduate from the Federal Law Enforcement Training, Center (FLETC) volunteered to participated in an exercise designed to evaluate their survivability. In a highly stressful interactive scenario, which included a Hostage Situation during a staged domestic dispute, performance was evaluated for a range of responses, including: weapon malfunction, shooting judgement and accuracy, communications, and emotional reactions. Nineteen percent of subjects shot the Hostage, a failure rate that falls in the reported range of friendly fire casualties in military combat. The Spielberger Trait Anger Scale showed an association with shot placement and performance during the gunfight, as well as with overall performance scores.

  • Evaluating Performance of Law Enforcement Personnel during a Stressful Training Scenario
    Annals of the New York Academy of Sciences, 2004
    Co-Authors: James L. Meyerhoff, William P. Norris, George A. Saviolakis, Terry Wollert, Bob Burge, Valerie Atkins, Charles D. Spielberger
    Abstract:

    Police trainees who were ready to graduate from the Federal Law Enforcement Training Center (FLETC) volunteered to participate in an exercise designed to evaluate their survivability. In a highly stressful interactive scenario, which included a Hostage Situation, performance was evaluated for a range of responses, including: shooting judgment and accuracy, communications, and coping with a weapon malfunction. Nineteen percent of subjects shot the Hostage, a failure rate that falls in the reported range of friendly fire casualties in military combat. The Spielberger Trait Anger Scale showed an association with shot placement and performance during the gunfight as well as with overall performance scores.

Saul Smilansky - One of the best experts on this subject based on the ideXlab platform.

  • A Hostage Situation
    The Journal of Philosophy, 2019
    Co-Authors: Saul Smilansky
    Abstract:

    Moral life sometimes involves life-and-death decisions, and philosophers often consider them by examining intuitions about ideal cases. Contemporary philosophical discourse on such matters has been dominated by Trolley-type cases, which typically present us with the need to make decisions on whether to sacrifice one person in order to save a larger number of similar others. Such cases lead to a distinct view of moral dilemmas and of moral life generally. The case I present here, “Hostage Situation,” is quite unlike them and should generate intuitions that differ greatly from those brought forth by standard Trolley-type cases. The implications are surprising and suggest that familiar and widely prevalent perceptions of the normative field are inadequate.

Marilyn A Huestis - One of the best experts on this subject based on the ideXlab platform.

  • metabolism of carfentanil an ultra potent opioid in human liver microsomes and human hepatocytes by high resolution mass spectrometry
    Aaps Journal, 2016
    Co-Authors: Michael G Feasel, Ariane Wohlfarth, John Michael Nilles, Shaokun Pang, Robert L Kristovich, Marilyn A Huestis
    Abstract:

    Carfentanil is an ultra-potent synthetic opioid. No human carfentanil metabolism data are available. Reportedly, Russian police forces used carfentanil and remifentanil to resolve a Hostage Situation in Moscow in 2002. This alleged use prompted interest in the pharmacology and toxicology of carfentanil in humans. Our study was conducted to identify human carfentanil metabolites and to assess carfentanil’s metabolic clearance, which could contribute to its acute toxicity in humans. We used Simulations Plus’s ADMET Predictor™ and Molecular Discovery’s MetaSite™ to predict possible metabolite formation. Both programs gave similar results that were generally good but did not capture all metabolites seen in vitro. We incubated carfentanil with human hepatocytes for up to 1 h and analyzed samples on a Sciex 3200 QTRAP mass spectrometer to measure parent compound depletion and extrapolated that to represent intrinsic clearance. Pooled primary human hepatocytes were then incubated with carfentanil up to 6 h and analyzed for metabolite identification on a Sciex 5600+ TripleTOF (QTOF) high-resolution mass spectrometer. MS and MS/MS analyses elucidated the structures of the most abundant metabolites. Twelve metabolites were identified in total. N-Dealkylation and monohydroxylation of the piperidine ring were the dominant metabolic pathways. Two N-oxide metabolites and one glucuronide metabolite were observed. Surprisingly, ester hydrolysis was not a major metabolic pathway for carfentanil. While the human liver microsomal system demonstrated rapid clearance by CYP enzymes, the hepatocyte incubations showed much slower clearance, possibly providing some insight into the long duration of carfentanil’s effects.

William P. Norris - One of the best experts on this subject based on the ideXlab platform.

  • Errors in Shooting Judgment and Performance by Law Enforcement Personnel During a Stressful Training Scenario
    2004
    Co-Authors: James L. Meyerhoff, William P. Norris, George A. Saviolakis, Terry Wollert, Bob Burge, Valerie Atkins, Charles D. Spielberger
    Abstract:

    Abstract : Police trainees who were ready to graduate from the Federal Law Enforcement Training, Center (FLETC) volunteered to participated in an exercise designed to evaluate their survivability. In a highly stressful interactive scenario, which included a Hostage Situation during a staged domestic dispute, performance was evaluated for a range of responses, including: weapon malfunction, shooting judgement and accuracy, communications, and emotional reactions. Nineteen percent of subjects shot the Hostage, a failure rate that falls in the reported range of friendly fire casualties in military combat. The Spielberger Trait Anger Scale showed an association with shot placement and performance during the gunfight, as well as with overall performance scores.

  • Evaluating Performance of Law Enforcement Personnel during a Stressful Training Scenario
    Annals of the New York Academy of Sciences, 2004
    Co-Authors: James L. Meyerhoff, William P. Norris, George A. Saviolakis, Terry Wollert, Bob Burge, Valerie Atkins, Charles D. Spielberger
    Abstract:

    Police trainees who were ready to graduate from the Federal Law Enforcement Training Center (FLETC) volunteered to participate in an exercise designed to evaluate their survivability. In a highly stressful interactive scenario, which included a Hostage Situation, performance was evaluated for a range of responses, including: shooting judgment and accuracy, communications, and coping with a weapon malfunction. Nineteen percent of subjects shot the Hostage, a failure rate that falls in the reported range of friendly fire casualties in military combat. The Spielberger Trait Anger Scale showed an association with shot placement and performance during the gunfight as well as with overall performance scores.