The Experts below are selected from a list of 855 Experts worldwide ranked by ideXlab platform
Lorraine Ramig - One of the best experts on this subject based on the ideXlab platform.
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neural correlates of efficacy of voice therapy in parkinson s disease identified by performance correlation analysis
Human Brain Mapping, 2009Co-Authors: Shalini Narayana, Wei Zhang, Crystal Franklin, Donald A Robin, Deanie Vogel, Lorraine RamigAbstract:LSVT® LOUD (Lee Silverman Voice Treatment) is efficacious in the treatment of speech disorders in idiopathic Parkinson’s disease (IPD), particularly Hypophonia. Functional imaging in patients with IPD has shown abnormalities in several speech regions and changes in these areas immediately following treatment. This study serves to extend the analysis by correlating changes of regional neural activity with the main behavioral change following treatment, namely, increased vocal intensity. Ten IPD participants with Hypophonia were studied before and after LSVT LOUD. Cerebral blood flow during rest and reading conditions were measured by H215O-positron emission tomography. Z-score images were generated by contrasting reading with rest conditions for pre- and post-LSVT LOUD sessions. Neuronal activity during reading in the pre- versus post-LSVT LOUD contrast was correlated with corresponding change in vocal intensity to generate correlation images. Behaviorally, vocal intensity for speech tasks increased significantly after LSVT LOUD. The contrast and correlation analyses indicate a treatment-dependent shift to the right hemisphere with modification in the speech motor regions as well as in prefrontal and temporal areas. We interpret the modification of activity in these regions to be a top–down effect of LSVT LOUD. The absence of an effect of LSVT LOUD on the basal ganglion supports this argument. Our findings indicate that the therapeutic effect of LSVT LOUD in IPD Hypophonia results from a shift in cortical activity to the right hemisphere. These findings demonstrate that the short-term changes in the speech motor and multimodal integration areas can occur in a top–down manner.
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Neural Correlates of Efficacy of Voice Therapy in Parkinson’s Disease Identified by Performance–Correlation Analysis
Human Brain Mapping, 2009Co-Authors: Shalini Narayana, Wei Zhang, Crystal Franklin, Donald A Robin, Deanie Vogel, Lorraine RamigAbstract:LSVT® LOUD (Lee Silverman Voice Treatment) is efficacious in the treatment of speech disorders in idiopathic Parkinson’s disease (IPD), particularly Hypophonia. Functional imaging in patients with IPD has shown abnormalities in several speech regions and changes in these areas immediately following treatment. This study serves to extend the analysis by correlating changes of regional neural activity with the main behavioral change following treatment, namely, increased vocal intensity. Ten IPD participants with Hypophonia were studied before and after LSVT LOUD. Cerebral blood flow during rest and reading conditions were measured by H215O-positron emission tomography. Z-score images were generated by contrasting reading with rest conditions for pre- and post-LSVT LOUD sessions. Neuronal activity during reading in the pre- versus post-LSVT LOUD contrast was correlated with corresponding change in vocal intensity to generate correlation images. Behaviorally, vocal intensity for speech tasks increased significantly after LSVT LOUD. The contrast and correlation analyses indicate a treatment-dependent shift to the right hemisphere with modification in the speech motor regions as well as in prefrontal and temporal areas. We interpret the modification of activity in these regions to be a top–down effect of LSVT LOUD. The absence of an effect of LSVT LOUD on the basal ganglion supports this argument. Our findings indicate that the therapeutic effect of LSVT LOUD in IPD Hypophonia results from a shift in cortical activity to the right hemisphere. These findings demonstrate that the short-term changes in the speech motor and multimodal integration areas can occur in a top–down manner.
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Hypophonia in parkinson s disease neural correlates of voice treatment revealed by pet
Neurology, 2003Co-Authors: Mario Liotti, Deanie Vogel, Lorraine Ramig, C I Cook, Roger J Ingham, Janis C InghamAbstract:Objective: To investigate the neural correlates of Hypophonia in individuals with idiopathic PD (IPD) before and after voice treatment with the Lee Silverman Voice Treatment method (VT) using 15 O-H 2 O PET. Methods: Regional cerebral blood flow (rCBF) changes associated with overt speech–motor tasks relative to the resting state were measured in the IPD subjects before and after VT, and in a group of healthy control volunteers. Results: Behavioral measures of voice loudness significantly improved following treatment. Before VT, patients had strong speech-related activations in motor and premotor cortex (M1-mouth, supplementary motor cortex [SMA], and inferior lateral premotor cortex [ILPm]), which were significantly reduced post-VT. Similar to the post-treatment session, premotor activations were absent (SMA) or below statistical threshold (M1-mouth) in the healthy control group. In addition, following VT treatment, significant right-sided activations were present in anterior insular cortex, caudate head, putamen, and dorsolateral prefrontal cortex (DLPFC). Finally, the VT-induced neural changes were not present with transient experimenter-cued increases of loudness in VT-untreated patients. Conclusions: Effective improvement of IPD Hypophonia following voice treatment with VT was accompanied by a reduction of cortical motor–premotor activations, resembling the functional pattern observed in healthy volunteers and suggesting normalization, and additional recruitment of right anterior insula, caudate head, putamen, and DLPFC. This treatment-dependent functional reorganization suggests a shift from an abnormally effortful (premotor cortex) to a more automatic (basal ganglia, anterior insula) implementation of speech–motor actions.
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Hypophonia in Parkinson’s disease Neural correlates of voice treatment revealed by PET
Neurology, 2003Co-Authors: Mario Liotti, Deanie Vogel, Lorraine Ramig, C I Cook, Roger J Ingham, Janis C InghamAbstract:Objective: To investigate the neural correlates of Hypophonia in individuals with idiopathic PD (IPD) before and after voice treatment with the Lee Silverman Voice Treatment method (VT) using 15 O-H 2 O PET. Methods: Regional cerebral blood flow (rCBF) changes associated with overt speech–motor tasks relative to the resting state were measured in the IPD subjects before and after VT, and in a group of healthy control volunteers. Results: Behavioral measures of voice loudness significantly improved following treatment. Before VT, patients had strong speech-related activations in motor and premotor cortex (M1-mouth, supplementary motor cortex [SMA], and inferior lateral premotor cortex [ILPm]), which were significantly reduced post-VT. Similar to the post-treatment session, premotor activations were absent (SMA) or below statistical threshold (M1-mouth) in the healthy control group. In addition, following VT treatment, significant right-sided activations were present in anterior insular cortex, caudate head, putamen, and dorsolateral prefrontal cortex (DLPFC). Finally, the VT-induced neural changes were not present with transient experimenter-cued increases of loudness in VT-untreated patients. Conclusions: Effective improvement of IPD Hypophonia following voice treatment with VT was accompanied by a reduction of cortical motor–premotor activations, resembling the functional pattern observed in healthy volunteers and suggesting normalization, and additional recruitment of right anterior insula, caudate head, putamen, and DLPFC. This treatment-dependent functional reorganization suggests a shift from an abnormally effortful (premotor cortex) to a more automatic (basal ganglia, anterior insula) implementation of speech–motor actions.
Scott G. Adams - One of the best experts on this subject based on the ideXlab platform.
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a comparison of speech amplification and personal communication devices for Hypophonia
Journal of Speech Language and Hearing Research, 2020Co-Authors: Thea Knowles, Scott G. Adams, Allyson D Page, Daryn CushniesparrowAbstract:Purpose This study compared the performance of three amplification devices hypothesized to improve speech communication in individuals with Hypophonia (HP), as well as to identify individuals' devi...
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efficacy and acceptance of a lombard response device for Hypophonia in parkinson s disease
Canadian Journal of Neurological Sciences, 2020Co-Authors: Scott G. Adams, Niraj Kumar, Philippe Rizek, Angeline Hong, Jenny Zhang, Anita Senthinathan, Cynthia Mancinelli, Thea KnowlesAbstract:OBJECTIVE The purpose of this study was to examine the effectiveness, satisfaction, and acceptance of a low-cost Lombard-response (LR) device in a group of individuals with Parkinson's disease (IWPD) and their communication partners (CPs). METHOD Sixteen IWPD and Hypophonia and their CPs participated in the study. The IWPD wore a LR device that included a small MP3 player (Sony Walkman) and headphones playing a multi-talker noise audio file at 80 dB during lab-based speech tasks and during their daily conversational speech over a 2-week device trial period. Outcome measures included average conversational speech intensity and scores on a questionnaire related to speech impairment, communication effectiveness, and device satisfaction. RESULTS Conversational speech intensity of the IWPD is increased by 7 to 10 dB with the LR device. Following a 2-week trial period, eight of the IWPD (50%) gave the LR device moderate-to-high satisfaction and effectiveness ratings and decided to purchase the device for long-term daily use. At the 4-month follow-up, none of the IWPDs were still using the LR device. Device rejection was related to discomfort (loudness), headaches, interference with cognition, and difficulty controlling device. CONCLUSION Short-term acceptance and satisfaction with the LR device was moderate, but long-term acceptance, beyond 4 months, was absent. Future studies are required to determine if other types of low-cost LR devices can be developed that improve long-term efficacy and device acceptance in IWPD and Hypophonia.
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EMBC - Objective and Subjective Assessment of Amplified Parkinsonian Speech Quality
Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and, 2018Co-Authors: Amr Gaballah, Monika Andreetta, Vijay Parsa, Scott G. AdamsAbstract:Hypophonia is a common speech impairment associated with Parkinson’s disease (PD). Voice amplifiers are typically used to increase voice loudness, but little is known about their impact on perceived speech quality. In this paper, speech recordings were obtained from 11 PD subjects with and without the use of seven different amplification devices, and in the absence or presence of background noise. The recorded speech samples were rated for their sound quality by 10 naive listeners. The same speech recordings were analyzed objectively, where in linear prediction, mel-frequency cepstral coefficients (MFCCs), and gammatone cepstral coefficients (GFCCs) were extracted and mapped to predicted quality scores using linear regression and Support Vector Regression (SVR). Results showed that amplification devices differentially affect the perceived quality of PD speech, that objective and subjective quality scores correlated well, and that a reduced set of GFCC features mapped with SVR produced the best correlation with the subjective scores.
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Evaluation of Speech Amplification Devices in Parkinson's Disease.
American Journal of Speech-language Pathology, 2016Co-Authors: Monika Andreetta, Scott G. Adams, Allyson D. DykstraAbstract:Purpose The purpose of this study was to evaluate the efficacy of selected speech amplification devices in individuals with Hypophonia and idiopathic Parkinson's disease (PD). Method This study compared the effectiveness of seven devices (ADDvox, BoomVox, ChatterVox, Oticon Amigo, SoniVox, Spokeman, and Voicette) to unamplified speech for 11 participants with PD during conversation in 65-dB SPL multitalker noise, using experience ratings collected from participant questionnaires and speech performance measures (i.e., speech-to-noise ratio [SNR], speech intensity, and intelligibility) obtained from audio recordings. Results Compared with unamplified speech, device use increased SNR by 1.07–4.73 dB SPL and speech intensity by 1.1–5.1 dB SPL, and it significantly increased transcribed intelligibility from 13.8% to 58.9%. In addition, the type of device used significantly affected speech performance measures (e.g., BoomVox was significantly higher than most of the other devices for SNR, speech intensity, and ...
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Effect of concurrent walking and interlocutor distance on conversational speech intensity and rate in Parkinson's disease.
Gait & Posture, 2015Co-Authors: Cassandra M. Mccaig, Scott G. Adams, Allyson D. DykstraAbstract:Abstract Previous studies have demonstrated a negative effect of concurrent walking and talking on gait in Parkinson's disease (PD) but there is limited information about the effect of concurrent walking on speech production. The present study examined the effect of sitting, standing, and three concurrent walking tasks (slow, normal, fast) on conversational speech intensity and speech rate in fifteen individuals with Hypophonia related to idiopathic Parkinson's disease (PD) and fourteen age-equivalent controls. Interlocuter (talker-to-talker) distance effects and walking speed were also examined. Concurrent walking was found to produce a significant increase in speech intensity, relative to standing and sitting, in both the control and PD groups. Faster walking produced significantly greater speech intensity than slower walking. Concurrent walking had no effect on speech rate. Concurrent walking and talking produced significant reductions in walking speed in both the control and PD groups. In general, the results of the present study indicate that concurrent walking tasks and the speed of concurrent walking can have a significant positive effect on conversational speech intensity. These positive, “energizing” effects need to be given consideration in future attempts to develop a comprehensive model of speech intensity regulation and they may have important implications for the development of new evaluation and treatment procedures for individuals with Hypophonia related to PD.
Deanie Vogel - One of the best experts on this subject based on the ideXlab platform.
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neural correlates of efficacy of voice therapy in parkinson s disease identified by performance correlation analysis
Human Brain Mapping, 2009Co-Authors: Shalini Narayana, Wei Zhang, Crystal Franklin, Donald A Robin, Deanie Vogel, Lorraine RamigAbstract:LSVT® LOUD (Lee Silverman Voice Treatment) is efficacious in the treatment of speech disorders in idiopathic Parkinson’s disease (IPD), particularly Hypophonia. Functional imaging in patients with IPD has shown abnormalities in several speech regions and changes in these areas immediately following treatment. This study serves to extend the analysis by correlating changes of regional neural activity with the main behavioral change following treatment, namely, increased vocal intensity. Ten IPD participants with Hypophonia were studied before and after LSVT LOUD. Cerebral blood flow during rest and reading conditions were measured by H215O-positron emission tomography. Z-score images were generated by contrasting reading with rest conditions for pre- and post-LSVT LOUD sessions. Neuronal activity during reading in the pre- versus post-LSVT LOUD contrast was correlated with corresponding change in vocal intensity to generate correlation images. Behaviorally, vocal intensity for speech tasks increased significantly after LSVT LOUD. The contrast and correlation analyses indicate a treatment-dependent shift to the right hemisphere with modification in the speech motor regions as well as in prefrontal and temporal areas. We interpret the modification of activity in these regions to be a top–down effect of LSVT LOUD. The absence of an effect of LSVT LOUD on the basal ganglion supports this argument. Our findings indicate that the therapeutic effect of LSVT LOUD in IPD Hypophonia results from a shift in cortical activity to the right hemisphere. These findings demonstrate that the short-term changes in the speech motor and multimodal integration areas can occur in a top–down manner.
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Neural Correlates of Efficacy of Voice Therapy in Parkinson’s Disease Identified by Performance–Correlation Analysis
Human Brain Mapping, 2009Co-Authors: Shalini Narayana, Wei Zhang, Crystal Franklin, Donald A Robin, Deanie Vogel, Lorraine RamigAbstract:LSVT® LOUD (Lee Silverman Voice Treatment) is efficacious in the treatment of speech disorders in idiopathic Parkinson’s disease (IPD), particularly Hypophonia. Functional imaging in patients with IPD has shown abnormalities in several speech regions and changes in these areas immediately following treatment. This study serves to extend the analysis by correlating changes of regional neural activity with the main behavioral change following treatment, namely, increased vocal intensity. Ten IPD participants with Hypophonia were studied before and after LSVT LOUD. Cerebral blood flow during rest and reading conditions were measured by H215O-positron emission tomography. Z-score images were generated by contrasting reading with rest conditions for pre- and post-LSVT LOUD sessions. Neuronal activity during reading in the pre- versus post-LSVT LOUD contrast was correlated with corresponding change in vocal intensity to generate correlation images. Behaviorally, vocal intensity for speech tasks increased significantly after LSVT LOUD. The contrast and correlation analyses indicate a treatment-dependent shift to the right hemisphere with modification in the speech motor regions as well as in prefrontal and temporal areas. We interpret the modification of activity in these regions to be a top–down effect of LSVT LOUD. The absence of an effect of LSVT LOUD on the basal ganglion supports this argument. Our findings indicate that the therapeutic effect of LSVT LOUD in IPD Hypophonia results from a shift in cortical activity to the right hemisphere. These findings demonstrate that the short-term changes in the speech motor and multimodal integration areas can occur in a top–down manner.
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Hypophonia in parkinson s disease neural correlates of voice treatment revealed by pet
Neurology, 2003Co-Authors: Mario Liotti, Deanie Vogel, Lorraine Ramig, C I Cook, Roger J Ingham, Janis C InghamAbstract:Objective: To investigate the neural correlates of Hypophonia in individuals with idiopathic PD (IPD) before and after voice treatment with the Lee Silverman Voice Treatment method (VT) using 15 O-H 2 O PET. Methods: Regional cerebral blood flow (rCBF) changes associated with overt speech–motor tasks relative to the resting state were measured in the IPD subjects before and after VT, and in a group of healthy control volunteers. Results: Behavioral measures of voice loudness significantly improved following treatment. Before VT, patients had strong speech-related activations in motor and premotor cortex (M1-mouth, supplementary motor cortex [SMA], and inferior lateral premotor cortex [ILPm]), which were significantly reduced post-VT. Similar to the post-treatment session, premotor activations were absent (SMA) or below statistical threshold (M1-mouth) in the healthy control group. In addition, following VT treatment, significant right-sided activations were present in anterior insular cortex, caudate head, putamen, and dorsolateral prefrontal cortex (DLPFC). Finally, the VT-induced neural changes were not present with transient experimenter-cued increases of loudness in VT-untreated patients. Conclusions: Effective improvement of IPD Hypophonia following voice treatment with VT was accompanied by a reduction of cortical motor–premotor activations, resembling the functional pattern observed in healthy volunteers and suggesting normalization, and additional recruitment of right anterior insula, caudate head, putamen, and DLPFC. This treatment-dependent functional reorganization suggests a shift from an abnormally effortful (premotor cortex) to a more automatic (basal ganglia, anterior insula) implementation of speech–motor actions.
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Hypophonia in Parkinson’s disease Neural correlates of voice treatment revealed by PET
Neurology, 2003Co-Authors: Mario Liotti, Deanie Vogel, Lorraine Ramig, C I Cook, Roger J Ingham, Janis C InghamAbstract:Objective: To investigate the neural correlates of Hypophonia in individuals with idiopathic PD (IPD) before and after voice treatment with the Lee Silverman Voice Treatment method (VT) using 15 O-H 2 O PET. Methods: Regional cerebral blood flow (rCBF) changes associated with overt speech–motor tasks relative to the resting state were measured in the IPD subjects before and after VT, and in a group of healthy control volunteers. Results: Behavioral measures of voice loudness significantly improved following treatment. Before VT, patients had strong speech-related activations in motor and premotor cortex (M1-mouth, supplementary motor cortex [SMA], and inferior lateral premotor cortex [ILPm]), which were significantly reduced post-VT. Similar to the post-treatment session, premotor activations were absent (SMA) or below statistical threshold (M1-mouth) in the healthy control group. In addition, following VT treatment, significant right-sided activations were present in anterior insular cortex, caudate head, putamen, and dorsolateral prefrontal cortex (DLPFC). Finally, the VT-induced neural changes were not present with transient experimenter-cued increases of loudness in VT-untreated patients. Conclusions: Effective improvement of IPD Hypophonia following voice treatment with VT was accompanied by a reduction of cortical motor–premotor activations, resembling the functional pattern observed in healthy volunteers and suggesting normalization, and additional recruitment of right anterior insula, caudate head, putamen, and DLPFC. This treatment-dependent functional reorganization suggests a shift from an abnormally effortful (premotor cortex) to a more automatic (basal ganglia, anterior insula) implementation of speech–motor actions.
Janis C Ingham - One of the best experts on this subject based on the ideXlab platform.
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Hypophonia in parkinson s disease neural correlates of voice treatment revealed by pet
Neurology, 2003Co-Authors: Mario Liotti, Deanie Vogel, Lorraine Ramig, C I Cook, Roger J Ingham, Janis C InghamAbstract:Objective: To investigate the neural correlates of Hypophonia in individuals with idiopathic PD (IPD) before and after voice treatment with the Lee Silverman Voice Treatment method (VT) using 15 O-H 2 O PET. Methods: Regional cerebral blood flow (rCBF) changes associated with overt speech–motor tasks relative to the resting state were measured in the IPD subjects before and after VT, and in a group of healthy control volunteers. Results: Behavioral measures of voice loudness significantly improved following treatment. Before VT, patients had strong speech-related activations in motor and premotor cortex (M1-mouth, supplementary motor cortex [SMA], and inferior lateral premotor cortex [ILPm]), which were significantly reduced post-VT. Similar to the post-treatment session, premotor activations were absent (SMA) or below statistical threshold (M1-mouth) in the healthy control group. In addition, following VT treatment, significant right-sided activations were present in anterior insular cortex, caudate head, putamen, and dorsolateral prefrontal cortex (DLPFC). Finally, the VT-induced neural changes were not present with transient experimenter-cued increases of loudness in VT-untreated patients. Conclusions: Effective improvement of IPD Hypophonia following voice treatment with VT was accompanied by a reduction of cortical motor–premotor activations, resembling the functional pattern observed in healthy volunteers and suggesting normalization, and additional recruitment of right anterior insula, caudate head, putamen, and DLPFC. This treatment-dependent functional reorganization suggests a shift from an abnormally effortful (premotor cortex) to a more automatic (basal ganglia, anterior insula) implementation of speech–motor actions.
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Hypophonia in Parkinson’s disease Neural correlates of voice treatment revealed by PET
Neurology, 2003Co-Authors: Mario Liotti, Deanie Vogel, Lorraine Ramig, C I Cook, Roger J Ingham, Janis C InghamAbstract:Objective: To investigate the neural correlates of Hypophonia in individuals with idiopathic PD (IPD) before and after voice treatment with the Lee Silverman Voice Treatment method (VT) using 15 O-H 2 O PET. Methods: Regional cerebral blood flow (rCBF) changes associated with overt speech–motor tasks relative to the resting state were measured in the IPD subjects before and after VT, and in a group of healthy control volunteers. Results: Behavioral measures of voice loudness significantly improved following treatment. Before VT, patients had strong speech-related activations in motor and premotor cortex (M1-mouth, supplementary motor cortex [SMA], and inferior lateral premotor cortex [ILPm]), which were significantly reduced post-VT. Similar to the post-treatment session, premotor activations were absent (SMA) or below statistical threshold (M1-mouth) in the healthy control group. In addition, following VT treatment, significant right-sided activations were present in anterior insular cortex, caudate head, putamen, and dorsolateral prefrontal cortex (DLPFC). Finally, the VT-induced neural changes were not present with transient experimenter-cued increases of loudness in VT-untreated patients. Conclusions: Effective improvement of IPD Hypophonia following voice treatment with VT was accompanied by a reduction of cortical motor–premotor activations, resembling the functional pattern observed in healthy volunteers and suggesting normalization, and additional recruitment of right anterior insula, caudate head, putamen, and DLPFC. This treatment-dependent functional reorganization suggests a shift from an abnormally effortful (premotor cortex) to a more automatic (basal ganglia, anterior insula) implementation of speech–motor actions.
Alvaro Pascualleone - One of the best experts on this subject based on the ideXlab platform.
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cerebral deep venous thrombosis presenting as acute micrographia and Hypophonia
Neurology, 2000Co-Authors: Brian J Murray, Rafael H Llinas, Louis R Caplan, Thomas E Scammell, Alvaro PascualleoneAbstract:Article abstract Deep cerebral venous thrombosis is often a devastating condition associated with hemorrhagic infarction. We describe a patient who presented with acute micrographia and Hypophonia as the sole manifestations of extensive deep venous sinus thrombosis.