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Dushyant V. Sahani - One of the best experts on this subject based on the ideXlab platform.
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success of Image Guided Biopsy for small 3 cm focal liver lesions in cirrhotic and noncirrhotic individuals
Journal of Vascular and Interventional Radiology, 2010Co-Authors: Ronald S. Arellano, Debra A. Gervais, Peter F. Hahn, Peter R. Mueller, Dushyant V. SahaniAbstract:Purpose Imaging techniques can detect small liver lesions, although these are a challenge to Biopsy, particularly in cirrhotic liver. The authors assessed the diagnostic success of Image-Guided biopsies collected from small (≤ 3 cm) focal liver lesions. Materials and Methods This single-center, retrospective study included 374 patients (199 men; mean age, 62 ± 15). Eighteen-gauge core Biopsy and 22-gauge fine needle aspiration (FNA) samples were collected from small focal liver lesions. Samples were compared by histology versus cytology, malignant versus benign, from lesions smaller versus larger than 1.5 cm, from livers with versus without cirrhosis, collected by computed tomography (CT) guidance versus ultrasound, and from different locations in the liver. Results The combined accuracy of core Biopsy plus FNA analysis was 95.5%; core Biopsy alone characterized 93.3% of samples, and FNA alone characterized 72.5% ( P P > .05). Biopsy characterized 95.3% (102 of 107) lesions ≤ 1.5 cm. The success in cirrhotic livers was 94.8%, for CT-Guided biopsies was 95%, and for ultrasound-Guided biopsies was 95.8% ( P > .05). The success rate was lower in liver caudate lobe than in other locations ( P Conclusions Image-Guided Biopsy of small (≤ 3 cm) focal liver lesions is highly reliable with the use of core Biopsy alone. Neither size ≤ 1.5 cm nor presence of cirrhosis is an impediment to Biopsy. CT and ultrasound guidance produce similar rates of success.
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Success of Image-Guided Biopsy for small (≤ 3 cm) focal liver lesions in cirrhotic and noncirrhotic individuals.
Journal of vascular and interventional radiology : JVIR, 2010Co-Authors: Ronald S. Arellano, Debra A. Gervais, Peter F. Hahn, Peter R. Mueller, Dushyant V. SahaniAbstract:Purpose Imaging techniques can detect small liver lesions, although these are a challenge to Biopsy, particularly in cirrhotic liver. The authors assessed the diagnostic success of Image-Guided biopsies collected from small (≤ 3 cm) focal liver lesions. Materials and Methods This single-center, retrospective study included 374 patients (199 men; mean age, 62 ± 15). Eighteen-gauge core Biopsy and 22-gauge fine needle aspiration (FNA) samples were collected from small focal liver lesions. Samples were compared by histology versus cytology, malignant versus benign, from lesions smaller versus larger than 1.5 cm, from livers with versus without cirrhosis, collected by computed tomography (CT) guidance versus ultrasound, and from different locations in the liver. Results The combined accuracy of core Biopsy plus FNA analysis was 95.5%; core Biopsy alone characterized 93.3% of samples, and FNA alone characterized 72.5% ( P P > .05). Biopsy characterized 95.3% (102 of 107) lesions ≤ 1.5 cm. The success in cirrhotic livers was 94.8%, for CT-Guided biopsies was 95%, and for ultrasound-Guided biopsies was 95.8% ( P > .05). The success rate was lower in liver caudate lobe than in other locations ( P Conclusions Image-Guided Biopsy of small (≤ 3 cm) focal liver lesions is highly reliable with the use of core Biopsy alone. Neither size ≤ 1.5 cm nor presence of cirrhosis is an impediment to Biopsy. CT and ultrasound guidance produce similar rates of success.
Peter R. Mueller - One of the best experts on this subject based on the ideXlab platform.
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Image Guided Biopsy of suspicious lymph nodes in patients with known primary malignancies
Journal of Vascular and Interventional Radiology, 2012Co-Authors: Shaunagh Mcdermott, Peter F. Hahn, Peter R. Mueller, Sandeep Hedgire, Mukesh G HarisinghaniAbstract:Abstract Purpose To determine how often abdominal, pelvic, and inguinal lymphadenopathy in patients with a known malignancy arises from a second primary cancer or from benign causes, rather than from the cancer already known. Materials and Methods A total of 196 patients with a history of a single Biopsy-proven malignancy underwent Image-Guided abdominal or pelvic lymph node (LN) biopsies between January 2000 and January 2005. Three patients were excluded. The medical records and imaging of the remaining 193 patients were reviewed. Pathologic results were assigned to one of three outcomes: LN involvement by known malignancy, newly diagnosed malignancy, or no malignancy identified. Patients in whom malignancy was not identified required repeat Biopsy or stability or reduction in size of LN on follow-up imaging for confirmation while not receiving treatment. Results Of the 193 included biopsies, there was LN involvement by the known malignancy in 148 (76.7%; 95% CI, 70.1%–82.5%), a newly diagnosed malignancy in 19 (9.8%; 95% CI, 6.0%–14.9%), and no malignancy identified in 26 (13.5%; 95% CI, 9.0%–19.1%). Conclusions Biopsy of a suspicious abdominal or pelvic LN in patients with known malignancy reveals a newly diagnosed malignancy or no evidence of malignancy in 23% of cases, emphasizing the importance of Biopsy.
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success of Image Guided Biopsy for small 3 cm focal liver lesions in cirrhotic and noncirrhotic individuals
Journal of Vascular and Interventional Radiology, 2010Co-Authors: Ronald S. Arellano, Debra A. Gervais, Peter F. Hahn, Peter R. Mueller, Dushyant V. SahaniAbstract:Purpose Imaging techniques can detect small liver lesions, although these are a challenge to Biopsy, particularly in cirrhotic liver. The authors assessed the diagnostic success of Image-Guided biopsies collected from small (≤ 3 cm) focal liver lesions. Materials and Methods This single-center, retrospective study included 374 patients (199 men; mean age, 62 ± 15). Eighteen-gauge core Biopsy and 22-gauge fine needle aspiration (FNA) samples were collected from small focal liver lesions. Samples were compared by histology versus cytology, malignant versus benign, from lesions smaller versus larger than 1.5 cm, from livers with versus without cirrhosis, collected by computed tomography (CT) guidance versus ultrasound, and from different locations in the liver. Results The combined accuracy of core Biopsy plus FNA analysis was 95.5%; core Biopsy alone characterized 93.3% of samples, and FNA alone characterized 72.5% ( P P > .05). Biopsy characterized 95.3% (102 of 107) lesions ≤ 1.5 cm. The success in cirrhotic livers was 94.8%, for CT-Guided biopsies was 95%, and for ultrasound-Guided biopsies was 95.8% ( P > .05). The success rate was lower in liver caudate lobe than in other locations ( P Conclusions Image-Guided Biopsy of small (≤ 3 cm) focal liver lesions is highly reliable with the use of core Biopsy alone. Neither size ≤ 1.5 cm nor presence of cirrhosis is an impediment to Biopsy. CT and ultrasound guidance produce similar rates of success.
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Success of Image-Guided Biopsy for small (≤ 3 cm) focal liver lesions in cirrhotic and noncirrhotic individuals.
Journal of vascular and interventional radiology : JVIR, 2010Co-Authors: Ronald S. Arellano, Debra A. Gervais, Peter F. Hahn, Peter R. Mueller, Dushyant V. SahaniAbstract:Purpose Imaging techniques can detect small liver lesions, although these are a challenge to Biopsy, particularly in cirrhotic liver. The authors assessed the diagnostic success of Image-Guided biopsies collected from small (≤ 3 cm) focal liver lesions. Materials and Methods This single-center, retrospective study included 374 patients (199 men; mean age, 62 ± 15). Eighteen-gauge core Biopsy and 22-gauge fine needle aspiration (FNA) samples were collected from small focal liver lesions. Samples were compared by histology versus cytology, malignant versus benign, from lesions smaller versus larger than 1.5 cm, from livers with versus without cirrhosis, collected by computed tomography (CT) guidance versus ultrasound, and from different locations in the liver. Results The combined accuracy of core Biopsy plus FNA analysis was 95.5%; core Biopsy alone characterized 93.3% of samples, and FNA alone characterized 72.5% ( P P > .05). Biopsy characterized 95.3% (102 of 107) lesions ≤ 1.5 cm. The success in cirrhotic livers was 94.8%, for CT-Guided biopsies was 95%, and for ultrasound-Guided biopsies was 95.8% ( P > .05). The success rate was lower in liver caudate lobe than in other locations ( P Conclusions Image-Guided Biopsy of small (≤ 3 cm) focal liver lesions is highly reliable with the use of core Biopsy alone. Neither size ≤ 1.5 cm nor presence of cirrhosis is an impediment to Biopsy. CT and ultrasound guidance produce similar rates of success.
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Impact of positive findings at Image-Guided Biopsy of lymphoma on patient care: evaluation of clinical history, needle size, and pathologic findings on Biopsy performance.
Radiology, 1994Co-Authors: Stuart G. Silverman, Peter R. Mueller, B. Y. Lee, Edmund S. Cibas, Steven E. SeltzerAbstract:PURPOSE: To analyze the effect of findings at Image-Guided Biopsy of abdominal lymphoma (IGBL) on patient care and define the key determinants of clinical success. MATERIALS AND METHODS: A retrospective, bi-institutional study was performed in 102 patients with positive or suspicious IGBL findings (93 patients with non-Hodgkin and nine patients with Hodgkin lymphoma). The proportion of patients treated on the basis of IGBL findings only was calculated and correlated with 10 determinants, including history of lymphoma, Biopsy technique, needle size, immunocytochemical findings, and tumor grade. RESULTS: Overall, 73 patients (72%) were treated on the basis of Biopsy findings only, including 41 (91%) of 45 patients with a history of lymphoma and 32 (56%) of 57 patients with no such history (P .50). CONCLUSION: Whenever findings were positive, IGBL provided enough tissue to enable treatment in most patients. Fine needle...
Ronald S. Arellano - One of the best experts on this subject based on the ideXlab platform.
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success of Image Guided Biopsy for small 3 cm focal liver lesions in cirrhotic and noncirrhotic individuals
Journal of Vascular and Interventional Radiology, 2010Co-Authors: Ronald S. Arellano, Debra A. Gervais, Peter F. Hahn, Peter R. Mueller, Dushyant V. SahaniAbstract:Purpose Imaging techniques can detect small liver lesions, although these are a challenge to Biopsy, particularly in cirrhotic liver. The authors assessed the diagnostic success of Image-Guided biopsies collected from small (≤ 3 cm) focal liver lesions. Materials and Methods This single-center, retrospective study included 374 patients (199 men; mean age, 62 ± 15). Eighteen-gauge core Biopsy and 22-gauge fine needle aspiration (FNA) samples were collected from small focal liver lesions. Samples were compared by histology versus cytology, malignant versus benign, from lesions smaller versus larger than 1.5 cm, from livers with versus without cirrhosis, collected by computed tomography (CT) guidance versus ultrasound, and from different locations in the liver. Results The combined accuracy of core Biopsy plus FNA analysis was 95.5%; core Biopsy alone characterized 93.3% of samples, and FNA alone characterized 72.5% ( P P > .05). Biopsy characterized 95.3% (102 of 107) lesions ≤ 1.5 cm. The success in cirrhotic livers was 94.8%, for CT-Guided biopsies was 95%, and for ultrasound-Guided biopsies was 95.8% ( P > .05). The success rate was lower in liver caudate lobe than in other locations ( P Conclusions Image-Guided Biopsy of small (≤ 3 cm) focal liver lesions is highly reliable with the use of core Biopsy alone. Neither size ≤ 1.5 cm nor presence of cirrhosis is an impediment to Biopsy. CT and ultrasound guidance produce similar rates of success.
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Success of Image-Guided Biopsy for small (≤ 3 cm) focal liver lesions in cirrhotic and noncirrhotic individuals.
Journal of vascular and interventional radiology : JVIR, 2010Co-Authors: Ronald S. Arellano, Debra A. Gervais, Peter F. Hahn, Peter R. Mueller, Dushyant V. SahaniAbstract:Purpose Imaging techniques can detect small liver lesions, although these are a challenge to Biopsy, particularly in cirrhotic liver. The authors assessed the diagnostic success of Image-Guided biopsies collected from small (≤ 3 cm) focal liver lesions. Materials and Methods This single-center, retrospective study included 374 patients (199 men; mean age, 62 ± 15). Eighteen-gauge core Biopsy and 22-gauge fine needle aspiration (FNA) samples were collected from small focal liver lesions. Samples were compared by histology versus cytology, malignant versus benign, from lesions smaller versus larger than 1.5 cm, from livers with versus without cirrhosis, collected by computed tomography (CT) guidance versus ultrasound, and from different locations in the liver. Results The combined accuracy of core Biopsy plus FNA analysis was 95.5%; core Biopsy alone characterized 93.3% of samples, and FNA alone characterized 72.5% ( P P > .05). Biopsy characterized 95.3% (102 of 107) lesions ≤ 1.5 cm. The success in cirrhotic livers was 94.8%, for CT-Guided biopsies was 95%, and for ultrasound-Guided biopsies was 95.8% ( P > .05). The success rate was lower in liver caudate lobe than in other locations ( P Conclusions Image-Guided Biopsy of small (≤ 3 cm) focal liver lesions is highly reliable with the use of core Biopsy alone. Neither size ≤ 1.5 cm nor presence of cirrhosis is an impediment to Biopsy. CT and ultrasound guidance produce similar rates of success.
Peter F. Hahn - One of the best experts on this subject based on the ideXlab platform.
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Image Guided Biopsy of suspicious lymph nodes in patients with known primary malignancies
Journal of Vascular and Interventional Radiology, 2012Co-Authors: Shaunagh Mcdermott, Peter F. Hahn, Peter R. Mueller, Sandeep Hedgire, Mukesh G HarisinghaniAbstract:Abstract Purpose To determine how often abdominal, pelvic, and inguinal lymphadenopathy in patients with a known malignancy arises from a second primary cancer or from benign causes, rather than from the cancer already known. Materials and Methods A total of 196 patients with a history of a single Biopsy-proven malignancy underwent Image-Guided abdominal or pelvic lymph node (LN) biopsies between January 2000 and January 2005. Three patients were excluded. The medical records and imaging of the remaining 193 patients were reviewed. Pathologic results were assigned to one of three outcomes: LN involvement by known malignancy, newly diagnosed malignancy, or no malignancy identified. Patients in whom malignancy was not identified required repeat Biopsy or stability or reduction in size of LN on follow-up imaging for confirmation while not receiving treatment. Results Of the 193 included biopsies, there was LN involvement by the known malignancy in 148 (76.7%; 95% CI, 70.1%–82.5%), a newly diagnosed malignancy in 19 (9.8%; 95% CI, 6.0%–14.9%), and no malignancy identified in 26 (13.5%; 95% CI, 9.0%–19.1%). Conclusions Biopsy of a suspicious abdominal or pelvic LN in patients with known malignancy reveals a newly diagnosed malignancy or no evidence of malignancy in 23% of cases, emphasizing the importance of Biopsy.
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success of Image Guided Biopsy for small 3 cm focal liver lesions in cirrhotic and noncirrhotic individuals
Journal of Vascular and Interventional Radiology, 2010Co-Authors: Ronald S. Arellano, Debra A. Gervais, Peter F. Hahn, Peter R. Mueller, Dushyant V. SahaniAbstract:Purpose Imaging techniques can detect small liver lesions, although these are a challenge to Biopsy, particularly in cirrhotic liver. The authors assessed the diagnostic success of Image-Guided biopsies collected from small (≤ 3 cm) focal liver lesions. Materials and Methods This single-center, retrospective study included 374 patients (199 men; mean age, 62 ± 15). Eighteen-gauge core Biopsy and 22-gauge fine needle aspiration (FNA) samples were collected from small focal liver lesions. Samples were compared by histology versus cytology, malignant versus benign, from lesions smaller versus larger than 1.5 cm, from livers with versus without cirrhosis, collected by computed tomography (CT) guidance versus ultrasound, and from different locations in the liver. Results The combined accuracy of core Biopsy plus FNA analysis was 95.5%; core Biopsy alone characterized 93.3% of samples, and FNA alone characterized 72.5% ( P P > .05). Biopsy characterized 95.3% (102 of 107) lesions ≤ 1.5 cm. The success in cirrhotic livers was 94.8%, for CT-Guided biopsies was 95%, and for ultrasound-Guided biopsies was 95.8% ( P > .05). The success rate was lower in liver caudate lobe than in other locations ( P Conclusions Image-Guided Biopsy of small (≤ 3 cm) focal liver lesions is highly reliable with the use of core Biopsy alone. Neither size ≤ 1.5 cm nor presence of cirrhosis is an impediment to Biopsy. CT and ultrasound guidance produce similar rates of success.
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Success of Image-Guided Biopsy for small (≤ 3 cm) focal liver lesions in cirrhotic and noncirrhotic individuals.
Journal of vascular and interventional radiology : JVIR, 2010Co-Authors: Ronald S. Arellano, Debra A. Gervais, Peter F. Hahn, Peter R. Mueller, Dushyant V. SahaniAbstract:Purpose Imaging techniques can detect small liver lesions, although these are a challenge to Biopsy, particularly in cirrhotic liver. The authors assessed the diagnostic success of Image-Guided biopsies collected from small (≤ 3 cm) focal liver lesions. Materials and Methods This single-center, retrospective study included 374 patients (199 men; mean age, 62 ± 15). Eighteen-gauge core Biopsy and 22-gauge fine needle aspiration (FNA) samples were collected from small focal liver lesions. Samples were compared by histology versus cytology, malignant versus benign, from lesions smaller versus larger than 1.5 cm, from livers with versus without cirrhosis, collected by computed tomography (CT) guidance versus ultrasound, and from different locations in the liver. Results The combined accuracy of core Biopsy plus FNA analysis was 95.5%; core Biopsy alone characterized 93.3% of samples, and FNA alone characterized 72.5% ( P P > .05). Biopsy characterized 95.3% (102 of 107) lesions ≤ 1.5 cm. The success in cirrhotic livers was 94.8%, for CT-Guided biopsies was 95%, and for ultrasound-Guided biopsies was 95.8% ( P > .05). The success rate was lower in liver caudate lobe than in other locations ( P Conclusions Image-Guided Biopsy of small (≤ 3 cm) focal liver lesions is highly reliable with the use of core Biopsy alone. Neither size ≤ 1.5 cm nor presence of cirrhosis is an impediment to Biopsy. CT and ultrasound guidance produce similar rates of success.
Debra A. Gervais - One of the best experts on this subject based on the ideXlab platform.
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success of Image Guided Biopsy for small 3 cm focal liver lesions in cirrhotic and noncirrhotic individuals
Journal of Vascular and Interventional Radiology, 2010Co-Authors: Ronald S. Arellano, Debra A. Gervais, Peter F. Hahn, Peter R. Mueller, Dushyant V. SahaniAbstract:Purpose Imaging techniques can detect small liver lesions, although these are a challenge to Biopsy, particularly in cirrhotic liver. The authors assessed the diagnostic success of Image-Guided biopsies collected from small (≤ 3 cm) focal liver lesions. Materials and Methods This single-center, retrospective study included 374 patients (199 men; mean age, 62 ± 15). Eighteen-gauge core Biopsy and 22-gauge fine needle aspiration (FNA) samples were collected from small focal liver lesions. Samples were compared by histology versus cytology, malignant versus benign, from lesions smaller versus larger than 1.5 cm, from livers with versus without cirrhosis, collected by computed tomography (CT) guidance versus ultrasound, and from different locations in the liver. Results The combined accuracy of core Biopsy plus FNA analysis was 95.5%; core Biopsy alone characterized 93.3% of samples, and FNA alone characterized 72.5% ( P P > .05). Biopsy characterized 95.3% (102 of 107) lesions ≤ 1.5 cm. The success in cirrhotic livers was 94.8%, for CT-Guided biopsies was 95%, and for ultrasound-Guided biopsies was 95.8% ( P > .05). The success rate was lower in liver caudate lobe than in other locations ( P Conclusions Image-Guided Biopsy of small (≤ 3 cm) focal liver lesions is highly reliable with the use of core Biopsy alone. Neither size ≤ 1.5 cm nor presence of cirrhosis is an impediment to Biopsy. CT and ultrasound guidance produce similar rates of success.
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Success of Image-Guided Biopsy for small (≤ 3 cm) focal liver lesions in cirrhotic and noncirrhotic individuals.
Journal of vascular and interventional radiology : JVIR, 2010Co-Authors: Ronald S. Arellano, Debra A. Gervais, Peter F. Hahn, Peter R. Mueller, Dushyant V. SahaniAbstract:Purpose Imaging techniques can detect small liver lesions, although these are a challenge to Biopsy, particularly in cirrhotic liver. The authors assessed the diagnostic success of Image-Guided biopsies collected from small (≤ 3 cm) focal liver lesions. Materials and Methods This single-center, retrospective study included 374 patients (199 men; mean age, 62 ± 15). Eighteen-gauge core Biopsy and 22-gauge fine needle aspiration (FNA) samples were collected from small focal liver lesions. Samples were compared by histology versus cytology, malignant versus benign, from lesions smaller versus larger than 1.5 cm, from livers with versus without cirrhosis, collected by computed tomography (CT) guidance versus ultrasound, and from different locations in the liver. Results The combined accuracy of core Biopsy plus FNA analysis was 95.5%; core Biopsy alone characterized 93.3% of samples, and FNA alone characterized 72.5% ( P P > .05). Biopsy characterized 95.3% (102 of 107) lesions ≤ 1.5 cm. The success in cirrhotic livers was 94.8%, for CT-Guided biopsies was 95%, and for ultrasound-Guided biopsies was 95.8% ( P > .05). The success rate was lower in liver caudate lobe than in other locations ( P Conclusions Image-Guided Biopsy of small (≤ 3 cm) focal liver lesions is highly reliable with the use of core Biopsy alone. Neither size ≤ 1.5 cm nor presence of cirrhosis is an impediment to Biopsy. CT and ultrasound guidance produce similar rates of success.