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Barbara Anne Croy - One of the best experts on this subject based on the ideXlab platform.

  • corrigendum to impact of placental growth factor deficiency on early mouse Implant Site angiogenesis placenta 35 2014 772 775
    Placenta, 2015
    Co-Authors: Matthew T. Rätsep, Michael A. Adams, Peter Carmeliet, Barbara Anne Croy
    Abstract:

    Corrigendum to “Impact of placental growth factor deficiency on early mouse Implant Site angiogenesis” [Placenta 35 (2014) 772e775] M.T. R€ atsep a, , P. Carmeliet , M.A. Adams , B.A. Croy a a Department of Biomedical and Molecular Sciences, Queen's University, Kingston, ON, Canada b Laboratory of Angiogenesis and Neurovascular Link, Vesalius Research Center, Department of Oncology, University of Leuven, Leuven, Belgium

  • Impact of placental growth factor deficiency on early mouse Implant Site angiogenesis.
    Placenta, 2014
    Co-Authors: Matthew T. Rätsep, Michael A. Adams, Peter Carmeliet, Barbara Anne Croy
    Abstract:

    Abstract Effects of placental growth factor (PGF), an angiokine product of fetal trophoblasts and maternal decidual cells, on early decidual angiogenesis are undefined. We used whole-mount immunofluorescence analyses to compare uterus and gestation day 4.5–9.5 mouse Implantation Sites that differed genetically in fetal or maternal PGF deficiency. Implant Site number and embryonic development were similar in Pgf −/− and Pgf +/+ females although Pgf −/− lymphatic vessels were anomalous. Correct, fine branching angiogenesis of anti-mesometrial vessels required both conceptus and maternal PGF; correct mesometrial branching angiogenesis depended solely upon conceptus PGF. Thus, PGF is non-redundant for optimizing branching angiogenesis in early decidua.

Matthew T. Rätsep - One of the best experts on this subject based on the ideXlab platform.

  • corrigendum to impact of placental growth factor deficiency on early mouse Implant Site angiogenesis placenta 35 2014 772 775
    Placenta, 2015
    Co-Authors: Matthew T. Rätsep, Michael A. Adams, Peter Carmeliet, Barbara Anne Croy
    Abstract:

    Corrigendum to “Impact of placental growth factor deficiency on early mouse Implant Site angiogenesis” [Placenta 35 (2014) 772e775] M.T. R€ atsep a, , P. Carmeliet , M.A. Adams , B.A. Croy a a Department of Biomedical and Molecular Sciences, Queen's University, Kingston, ON, Canada b Laboratory of Angiogenesis and Neurovascular Link, Vesalius Research Center, Department of Oncology, University of Leuven, Leuven, Belgium

  • Impact of placental growth factor deficiency on early mouse Implant Site angiogenesis.
    Placenta, 2014
    Co-Authors: Matthew T. Rätsep, Michael A. Adams, Peter Carmeliet, Barbara Anne Croy
    Abstract:

    Abstract Effects of placental growth factor (PGF), an angiokine product of fetal trophoblasts and maternal decidual cells, on early decidual angiogenesis are undefined. We used whole-mount immunofluorescence analyses to compare uterus and gestation day 4.5–9.5 mouse Implantation Sites that differed genetically in fetal or maternal PGF deficiency. Implant Site number and embryonic development were similar in Pgf −/− and Pgf +/+ females although Pgf −/− lymphatic vessels were anomalous. Correct, fine branching angiogenesis of anti-mesometrial vessels required both conceptus and maternal PGF; correct mesometrial branching angiogenesis depended solely upon conceptus PGF. Thus, PGF is non-redundant for optimizing branching angiogenesis in early decidua.

Peter Carmeliet - One of the best experts on this subject based on the ideXlab platform.

  • corrigendum to impact of placental growth factor deficiency on early mouse Implant Site angiogenesis placenta 35 2014 772 775
    Placenta, 2015
    Co-Authors: Matthew T. Rätsep, Michael A. Adams, Peter Carmeliet, Barbara Anne Croy
    Abstract:

    Corrigendum to “Impact of placental growth factor deficiency on early mouse Implant Site angiogenesis” [Placenta 35 (2014) 772e775] M.T. R€ atsep a, , P. Carmeliet , M.A. Adams , B.A. Croy a a Department of Biomedical and Molecular Sciences, Queen's University, Kingston, ON, Canada b Laboratory of Angiogenesis and Neurovascular Link, Vesalius Research Center, Department of Oncology, University of Leuven, Leuven, Belgium

  • Impact of placental growth factor deficiency on early mouse Implant Site angiogenesis.
    Placenta, 2014
    Co-Authors: Matthew T. Rätsep, Michael A. Adams, Peter Carmeliet, Barbara Anne Croy
    Abstract:

    Abstract Effects of placental growth factor (PGF), an angiokine product of fetal trophoblasts and maternal decidual cells, on early decidual angiogenesis are undefined. We used whole-mount immunofluorescence analyses to compare uterus and gestation day 4.5–9.5 mouse Implantation Sites that differed genetically in fetal or maternal PGF deficiency. Implant Site number and embryonic development were similar in Pgf −/− and Pgf +/+ females although Pgf −/− lymphatic vessels were anomalous. Correct, fine branching angiogenesis of anti-mesometrial vessels required both conceptus and maternal PGF; correct mesometrial branching angiogenesis depended solely upon conceptus PGF. Thus, PGF is non-redundant for optimizing branching angiogenesis in early decidua.

Michael A. Adams - One of the best experts on this subject based on the ideXlab platform.

  • corrigendum to impact of placental growth factor deficiency on early mouse Implant Site angiogenesis placenta 35 2014 772 775
    Placenta, 2015
    Co-Authors: Matthew T. Rätsep, Michael A. Adams, Peter Carmeliet, Barbara Anne Croy
    Abstract:

    Corrigendum to “Impact of placental growth factor deficiency on early mouse Implant Site angiogenesis” [Placenta 35 (2014) 772e775] M.T. R€ atsep a, , P. Carmeliet , M.A. Adams , B.A. Croy a a Department of Biomedical and Molecular Sciences, Queen's University, Kingston, ON, Canada b Laboratory of Angiogenesis and Neurovascular Link, Vesalius Research Center, Department of Oncology, University of Leuven, Leuven, Belgium

  • Impact of placental growth factor deficiency on early mouse Implant Site angiogenesis.
    Placenta, 2014
    Co-Authors: Matthew T. Rätsep, Michael A. Adams, Peter Carmeliet, Barbara Anne Croy
    Abstract:

    Abstract Effects of placental growth factor (PGF), an angiokine product of fetal trophoblasts and maternal decidual cells, on early decidual angiogenesis are undefined. We used whole-mount immunofluorescence analyses to compare uterus and gestation day 4.5–9.5 mouse Implantation Sites that differed genetically in fetal or maternal PGF deficiency. Implant Site number and embryonic development were similar in Pgf −/− and Pgf +/+ females although Pgf −/− lymphatic vessels were anomalous. Correct, fine branching angiogenesis of anti-mesometrial vessels required both conceptus and maternal PGF; correct mesometrial branching angiogenesis depended solely upon conceptus PGF. Thus, PGF is non-redundant for optimizing branching angiogenesis in early decidua.

Antonio Scarano - One of the best experts on this subject based on the ideXlab platform.

  • infrared thermographic evaluation of temperature modifications induced during Implant Site preparation with steel vs zirconia Implant drill
    Journal of Clinical Medicine, 2020
    Co-Authors: Antonio Scarano, Felice Lorusso, Sammy Noumbissi
    Abstract:

    Background: The heat produced during Implant Site osteotomy can potentially interfere with and influence the osseointegration process of a dental Implant. The objective of this in vitro investigation was to measure the temperature changes during simulated osteotomies in bovine rib bone. The measurements were made at the apical area of the osteotomies with steel Implant drills compared to zirconia Implant drills. Methods: Steel cylindrical drills (2 mm) and zirconia cylindrical drills (2 mm) were evaluated in vitro using bovine rib bone for a total of five groups based on the number of osteotomies performed with each drill: 10, 20, 40, 90, or 120 osteotomies. Bone and apical drill temperatures were measured by means of infrared thermography. The drilling time for each osteotomy was measured for each preparation. Results: Statistically significant differences were found in the temperature measurements in the bone and apical portion of the drills between the study groups (p < 0.05). A statistically significant difference was observed for drilling time preparation between steel cylindrical drill (2 mm) and zirconia cylindrical drills (2 mm) (p < 0.01). Conclusions: The drill material has an impact on the temperature changes that occur at its apical portion during bone preparation for Implant placement.

  • observational study on the preparation of the Implant Site with piezosurgery vs drill comparison between the two methods in terms of postoperative pain surgical times and operational advantages
    BioMed Research International, 2019
    Co-Authors: Michele Maglione, Felice Lorusso, Lorenzo Bevilacqua, Federica Dotto, Fulvia Costantinides, Antonio Scarano
    Abstract:

    Purpose. Recent advances show that ultrasonic Implant Site osteotomy is related to a decreased trauma and a better postoperative healing of the surgical Site when compared to traditional drilling techniques. The micrometric bone cutting control and the operative advantages related to the piezoelectric approach are also characterized by a learning curve for the clinician in surgical practice and an increased operative duration of the procedure. The aim of this investigation is to compare the operative time, the postoperative pain, and the amount of painkillers taken by the patient during the healing period. Methods. A total of 65 patients were treated at the Unit of Oral Surgery (Department of Medical Sciences, Surgery and Health, University of Trieste, Italy) using a split mouth model: 75 drill-inserted Implants (G1) and 75 piezoelectric device-inserted Implants (G2) were placed. The Visual Analogue Scale (VAS) was performed to evaluate the postoperative pain at 15 days from surgery. The operative time and frequency of intake of painkillers were measured. Results. The G1 and G2 groups showed a significant difference with a higher use of painkillers observed for G1. The G2 patients showed a lower level of pain (VAS) at all experimental times between 8 hours to 7 days ( ) postsurgery. At 15 days, the pain levels were similar for both groups. No differences were found in Site preparation duration between the study groups. Conclusions. The evidence supports the application of the piezoelectric approach compared to the drill’s osteotomy as a useful technique for Implant Site preparation. This trial is registered with NCT03978923 .

  • ultrasonic vs drill Implant Site preparation post operative pain measurement through vas swelling and crestal bone remodeling a randomized clinical study
    Materials, 2018
    Co-Authors: Antonio Scarano, Felice Lorusso, Francesco Carinci, Felice Festa, Lorenzo Evilacqua, Pablo Santos De Oliveira, Michele Maglione
    Abstract:

    Background: Piezosurgery is a surgical procedure that is able to perform osteotomies by a micrometric and selective cut of the bone tissue. The objective of this investigation was to evaluate two different techniques; an ultrasonic device, and a drill approach for Implant Site preparation. Methods: A total of fifty patients were recruited for the randomized clinical trial to receive dental Implants for fixed prosthetic restoration in the posterior mandible and were allotted to two groups. In Group A the Implant Site was prepared following a drilling technique, while in Group B the Implant Site was prepared using an ultrasonic device; moreover, the operative duration was recorded. Postoperative pain and swelling were evaluated at 1, 2, 4, and 6 days. The crestal bone resorption was measured at 3 months from Implant placement by a three-dimensional tomography evaluation. Results: The findings suggest that osteotomies performed by an ultrasonic device cause less pain and swelling. On the other hand, the piezoelectric preparation was characterized by a significative increase in the operative time. No statistical differences in crestal bone resorption were evident in the two different approaches. Conclusions: According to the outcome of the study, ultrasonic Implant bed preparation can be used with success in Implantology and could be considered a suitable alternative to traditional drilling techniques for dental fixture placement.

  • infrared thermographic evaluation of temperature modifications induced during Implant Site preparation with cylindrical versus conical drills
    Clinical Implant Dentistry and Related Research, 2011
    Co-Authors: Antonio Scarano, Francesco Carinci, Adriano Piattelli, Bartolomeo Assenza, Luigi Di Donato, Gian Luca Romani, Arcangelo Merla
    Abstract:

    Background: A few studies have investigated the influence of drilling on bone healing. Many factors have been reported to influence temperature rise during surgical preparation for Implant placement: drill geometry, drilling depth, sharpness of the cutting tool, drilling speed, pressure applied to the drill, use of graduated versus one-step drilling, intermittent versus continuous drilling, and use or not of irrigation. Purpose: The objective of this study was to quantify the temperature changes in cortical bone and at the apical portion of the drills during Implant Site preparation with a cylindrical Implant drill versus a conical Implant drill. Materials and Methods: Two Implant drill systems were evaluated in vitro using bovine femoral cortical bone. The two Implant drill systems evaluated in this study were system A (a cylindrical drill with triple twist drills) (Bone System, Milano, Italy) and system B (a conical drill with quadruple twist drills) (Bone System). Site preparation began, and the temperature of the cortical bone and at the apical portion of the drill was measured by the infrared thermography. Results: The mean temperature produced in the cortical bone during Implant preparation was 31.2 ± 0.5°C for the cylindrical drills and 29.1 ± 0.6°C for the conical drill. The mean temperature produced in the apical portion of the drill during Implant Site preparation was 32.1 ± 0.7°C for the cylindrical drill system and 29.6 ± 0.6°C for the conical drill. Statistically significant differences were found in the temperature measurements in the cortical bone in the two groups (p < .05). A statistically significant difference was observed for the temperature measurements in the apical portion of the drill in the two groups (p < .005). Discussion: The model system used in this work was able to evaluate the temperature in the cortical bone and in the apical portion of the drills; the temperature modifications in the apical portion of the drill seemed to be correlated to the drill geometry. The results of the present study showed that drill geometry seems to be an important factor in heat generation during Implant Site preparation. Conclusion: The drill geometry could explain the increased temperature in the apical portion of the drill.