The Experts below are selected from a list of 3363 Experts worldwide ranked by ideXlab platform

Jorge Del Torocervera - One of the best experts on this subject based on the ideXlab platform.

Jhijoung Wang - One of the best experts on this subject based on the ideXlab platform.

  • chronic Indwelling Urinary Catheter increase the risk of bladder cancer even in patients without spinal cord injury
    Medicine, 2015
    Co-Authors: Kuanchin Sung, Sherwei Lim, Chienhwa Liao, Fuwen Liang, Jhijoung Wang
    Abstract:

    AbstractChronic Indwelling Urinary Catheters (CIDCs) are known as a risk factor for bladder cancer in patients with spinal cord injury (SCI). This study examined the potential risk of bladder cancer from CIDCs in patients without SCI.The National Health Insurance Research Database in Taiwan was used

  • chronic Indwelling Urinary Catheter increase the risk of bladder cancer even in patients without spinal cord injury
    Medicine, 2015
    Co-Authors: Kuanchin Sung, Sherwei Lim, Chienhwa Liao, Fuwen Liang, Jhijoung Wang
    Abstract:

    Chronic Indwelling Urinary Catheters (CIDCs) are known as a risk factor for bladder cancer in patients with spinal cord injury (SCI). This study examined the potential risk of bladder cancer from CIDCs in patients without SCI.The National Health Insurance Research Database in Taiwan was used to identify SCI patients (N = 1816). This group was compared against a control CIDC cohort without SCI (N = 1816) and a reference cohort with normal individuals without SCI and a record of CIDC (N = 7264). Comparisons were made based on age and gender matching over a maximum of 11 follow-up years. The incidence risk and hazard ratio (HR) of bladder cancer were estimated in all 3 groups.During the follow-up period, the bladder cancer incidence rates were 68.90 and 102.53 per 100,000 person-years in the SCI and CIDC-non-SCI groups, respectively. These values were both higher than that of the reference cohort (12.00 per 100,000 person-years). Patients who had history of SCI (HR: 6.51; 95% CI, 2.56-16.52) or CIDC without SCI (HR: 9.11; 95% CI, 3.9-21.29) had a higher risk of bladder cancer compared with the reference cohort.Patients with CIDCs may have an increased risk of bladder cancer development, especially in older aged and male patients compared with general population.

Hsingying Wu - One of the best experts on this subject based on the ideXlab platform.

  • purple urine bag syndrome
    Canadian Medical Association Journal, 2008
    Co-Authors: Yaping Wu, Hsingying Wu
    Abstract:

    A 58-year-old man with an Indwelling Urinary Catheter began producing urine with a deep purple colour ([Figure 1][1]). The urine was alkaline (pH 7.8), and Proteus mirabilis Urinary tract infection was diagnosed. This so-called purple urine bag syndrome resolved after treatment with ceftazidime. The

David R Andes - One of the best experts on this subject based on the ideXlab platform.

  • Rat Indwelling Urinary Catheter Model of Candida albicans Biofilm Infection 2 3 4
    2020
    Co-Authors: Jeniel E Nett, Hiram Sanchez, Robert Zarnowski, Karen Marchillo, Erin Brooks, Jonathan Cabezas-olcoz, David R Andes
    Abstract:

    ABSTRACT 24 Indwelling Urinary Catheters are commonly used in the management of 25 hospitalized patients. Candida can adhere to the device surface and propagate 26 as a biofilm. These communities differ from free-floating Candida, exhibiting high 27 tolerance to antifungal therapy. The significance of Catheter-associated 28 candiduria is often unclear and treatment may be problematic considering the 29 biofilm drug resistant phenotype. Here we describe a rodent model for study of 30 Urinary Catheter-associated Candida albicans biofilm infection that mimics this 31 common process in patients. In the setting of a functioning, Indwelling Urinary 32 Catheter in a rat, Candida proliferated as a biofilm on the device surface

  • rat Indwelling Urinary Catheter model of candida albicans biofilm infection
    Infection and Immunity, 2014
    Co-Authors: Jeniel E Nett, Erin G Brooks, Jonathan Cabezasolcoz, Hiram Sanchez, Robert Zarnowski, Karen Marchillo, David R Andes
    Abstract:

    Indwelling Urinary Catheters are commonly used in the management of hospitalized patients. Candida can adhere to the device surface and propagate as a biofilm. These Candida biofilm communities differ from free-floating Candida, exhibiting high tolerance to antifungal therapy. The significance of Catheter-associated candiduria is often unclear, and treatment may be problematic considering the biofilm drug-resistant phenotype. Here we describe a rodent model for the study of Urinary Catheter-associated Candida albicans biofilm infection that mimics this common process in patients. In the setting of a functioning, Indwelling Urinary Catheter in a rat, Candida proliferated as a biofilm on the device surface. Characteristic biofilm architecture was observed, including adherent, filamentous cells embedded in an extracellular matrix. Similar to what occurs in human patients, animals with this infection developed candiduria and pyuria. Infection progressed to cystitis, and a biofilmlike covering was observed over the bladder surface. Furthermore, large numbers of C. albicans cells were dispersed into the urine from either the Catheter or bladder wall biofilm over the infection period. We successfully utilized the model to test the efficacy of antifungals, analyze transcriptional patterns, and examine the phenotype of a genetic mutant. The model should be useful for future investigations involving the pathogenesis, diagnosis, therapy, prevention, and drug resistance of Candida biofilms in the Urinary tract.

Pablo Demelorodriguez - One of the best experts on this subject based on the ideXlab platform.