The Experts below are selected from a list of 10875 Experts worldwide ranked by ideXlab platform

Guozhong Zhang - One of the best experts on this subject based on the ideXlab platform.

  • Pathogenicity differences between QX-like and Mass-type Infectious Bronchitis viruses
    Veterinary microbiology, 2017
    Co-Authors: Jinlong Cheng, Caiyun Huo, Jing Zhao, Tong Liu, Shihong Yan, Zhujun Wang, Guozhong Zhang
    Abstract:

    Infectious Bronchitis is a highly contagious, acute viral respiratory disease of chickens, caused by Infectious Bronchitis virus (IBV). In recent years, the isolation rate of QX-like IBV has increased in the world. To clarify this phenomenon and better understand the pathogenicity of QX-like IBV, we examined differences in pathogenicity between two IBV strains, SD and M41, which belong to QX-like and Mass-type IBV, respectively. SD strain was more virulent in 3-week-old specific-pathogen-free chickens than M41 strain causing higher mortality with severe renal lesions. The tissue distribution of the two virus strains was tested by real-time RT-PCR. The results showed that the viral genome copy numbers in the tissues of chickens inoculated with SD strain were higher than those in chickens inoculated with M41 strain, with the exception of the trachea and lung. This study indicates that there are tremendous differences in pathogenicity and tissue tropism between the QX-like strain and Mass-type strain. These findings may benefit the prevention of Infectious Bronchitis in the poultry industry in China.

Baoli Sun - One of the best experts on this subject based on the ideXlab platform.

  • complete genome sequence of a recombinant nephropathogenic Infectious Bronchitis virus strain in china
    Journal of Virology, 2012
    Co-Authors: Yu Xue, Qingmei Xie, Zhuanqiang Yan, Feng Chen, Jianping Qin, Baoli Sun
    Abstract:

    Recently, nephropathogenic Infectious Bronchitis virus (IBV) outbreaks have occurred in commercial broiler flocks and have been associated with a high incidence and morbidity in China. The CK/CH/Zhejiang/06/10 strain (IBV-YX10) was isolated from a 12-day-old broiler chicken in a flock of chickens with swollen speckled kidneys and distended ureters filled with uric acid in China in 2010. Here we reported the complete genomic sequence of the IBV-YX10 which was a natural recombinant nephropathogenic Infectious Bronchitis virus strain. These findings will contribute additional insights into the molecular characteristics of evolving IBV genomes and the need for effective control of IBV in China.

Magdy F. El-kady - One of the best experts on this subject based on the ideXlab platform.

Jinlong Cheng - One of the best experts on this subject based on the ideXlab platform.

  • Pathogenicity differences between QX-like and Mass-type Infectious Bronchitis viruses
    Veterinary microbiology, 2017
    Co-Authors: Jinlong Cheng, Caiyun Huo, Jing Zhao, Tong Liu, Shihong Yan, Zhujun Wang, Guozhong Zhang
    Abstract:

    Infectious Bronchitis is a highly contagious, acute viral respiratory disease of chickens, caused by Infectious Bronchitis virus (IBV). In recent years, the isolation rate of QX-like IBV has increased in the world. To clarify this phenomenon and better understand the pathogenicity of QX-like IBV, we examined differences in pathogenicity between two IBV strains, SD and M41, which belong to QX-like and Mass-type IBV, respectively. SD strain was more virulent in 3-week-old specific-pathogen-free chickens than M41 strain causing higher mortality with severe renal lesions. The tissue distribution of the two virus strains was tested by real-time RT-PCR. The results showed that the viral genome copy numbers in the tissues of chickens inoculated with SD strain were higher than those in chickens inoculated with M41 strain, with the exception of the trachea and lung. This study indicates that there are tremendous differences in pathogenicity and tissue tropism between the QX-like strain and Mass-type strain. These findings may benefit the prevention of Infectious Bronchitis in the poultry industry in China.

Yu Xue - One of the best experts on this subject based on the ideXlab platform.

  • complete genome sequence of a recombinant nephropathogenic Infectious Bronchitis virus strain in china
    Journal of Virology, 2012
    Co-Authors: Yu Xue, Qingmei Xie, Zhuanqiang Yan, Feng Chen, Jianping Qin, Baoli Sun
    Abstract:

    Recently, nephropathogenic Infectious Bronchitis virus (IBV) outbreaks have occurred in commercial broiler flocks and have been associated with a high incidence and morbidity in China. The CK/CH/Zhejiang/06/10 strain (IBV-YX10) was isolated from a 12-day-old broiler chicken in a flock of chickens with swollen speckled kidneys and distended ureters filled with uric acid in China in 2010. Here we reported the complete genomic sequence of the IBV-YX10 which was a natural recombinant nephropathogenic Infectious Bronchitis virus strain. These findings will contribute additional insights into the molecular characteristics of evolving IBV genomes and the need for effective control of IBV in China.