The Experts below are selected from a list of 315 Experts worldwide ranked by ideXlab platform
R.s. Mcclelland - One of the best experts on this subject based on the ideXlab platform.
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P03.19 Screening for sexually transmitted infections in adolescent girls and young women in mombasa, kenya
Sexually Transmitted Infections, 2015Co-Authors: Linnet Masese, George Wanje, Ethel Avuvika, Emmanuel Kabare, V Budambula, Francis M. Mutuku, Grace Omoni, A Baghazal, Barbra A. Richardson, R.s. McclellandAbstract:Introduction As adolescents and young women become sexually active, they are at risk of adverse reproductive health outcomes including sexually transmitted infections (STIs). We assessed feasibility and acceptability of STI screening among 15–24 year-old women in Mombasa County, Kenya. Methods Participants were recruited from three high schools and one university. Study staff conducted informational sessions. Students interested in participating were given Informed Assent/consent forms to take home, and asked to visit our clinic for STI screening. During clinic visits, participants completed a self-administered questionnaire and provided a urine specimen to test for Neisseria gonorrhoeae , Chlamydia trachomatis , and Trichomonas vaginalis using the Hologic Aptima Detection System. Results Between August 2014 and March 2015, 463 high school and 165 university students collected Assent/consent forms. Of these, 293 (63%) from high schools versus 158 (95%) from university attended clinic for STI screening (p N. gonorrhoeae , 16 [3.6%] with C. trachomatis and 3 [0.7%] with T. vaginalis ). Older age (OR 1.28; 95% CI 1.07–1.53), reporting vaginal sex (OR 5.89; 95% CI 2.42–14.36), non-penetrative sex (OR 3.47; 95% CI 1.56–7.75), alcohol use (OR 3.34; 95% CI 1.26–8.87), smoking (OR 5.82; 95% CI 1.12–30.37), chewing khat (OR 3.19; 95% CI 1.27–8.01), and being at university rather than high school (OR 4.58; 95% CI 1.94–10.79) were associated with increased likelihood of STI (p ≤ 0.05). Condom use was protective (OR 0.32; 95% CI 0.11–0.94). Conclusion There was considerable demand for STI screening, and a substantial burden of STIs was observed. These findings support the need for reproductive health interventions to reduce adolescent risk for STIs, pregnancy, and their complications. Disclosure of interest statement This research was funded by a 2011 developmental grant from the University of Washington Global Centre for Integrated Health of Women, Adolescents, and Children (Global WACh).
Linnet Masese - One of the best experts on this subject based on the ideXlab platform.
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P03.19 Screening for sexually transmitted infections in adolescent girls and young women in mombasa, kenya
Sexually Transmitted Infections, 2015Co-Authors: Linnet Masese, George Wanje, Ethel Avuvika, Emmanuel Kabare, V Budambula, Francis M. Mutuku, Grace Omoni, A Baghazal, Barbra A. Richardson, R.s. McclellandAbstract:Introduction As adolescents and young women become sexually active, they are at risk of adverse reproductive health outcomes including sexually transmitted infections (STIs). We assessed feasibility and acceptability of STI screening among 15–24 year-old women in Mombasa County, Kenya. Methods Participants were recruited from three high schools and one university. Study staff conducted informational sessions. Students interested in participating were given Informed Assent/consent forms to take home, and asked to visit our clinic for STI screening. During clinic visits, participants completed a self-administered questionnaire and provided a urine specimen to test for Neisseria gonorrhoeae , Chlamydia trachomatis , and Trichomonas vaginalis using the Hologic Aptima Detection System. Results Between August 2014 and March 2015, 463 high school and 165 university students collected Assent/consent forms. Of these, 293 (63%) from high schools versus 158 (95%) from university attended clinic for STI screening (p N. gonorrhoeae , 16 [3.6%] with C. trachomatis and 3 [0.7%] with T. vaginalis ). Older age (OR 1.28; 95% CI 1.07–1.53), reporting vaginal sex (OR 5.89; 95% CI 2.42–14.36), non-penetrative sex (OR 3.47; 95% CI 1.56–7.75), alcohol use (OR 3.34; 95% CI 1.26–8.87), smoking (OR 5.82; 95% CI 1.12–30.37), chewing khat (OR 3.19; 95% CI 1.27–8.01), and being at university rather than high school (OR 4.58; 95% CI 1.94–10.79) were associated with increased likelihood of STI (p ≤ 0.05). Condom use was protective (OR 0.32; 95% CI 0.11–0.94). Conclusion There was considerable demand for STI screening, and a substantial burden of STIs was observed. These findings support the need for reproductive health interventions to reduce adolescent risk for STIs, pregnancy, and their complications. Disclosure of interest statement This research was funded by a 2011 developmental grant from the University of Washington Global Centre for Integrated Health of Women, Adolescents, and Children (Global WACh).
Emma Kearney - One of the best experts on this subject based on the ideXlab platform.
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promoting children s Informed Assent in research participation
International Journal of Qualitative Studies in Education, 2013Co-Authors: Sue Dockett, Bob Perry, Emma KearneyAbstract:Informed agreement to participate in research is a critical element of ethical practice. When researching with children, opportunities to provide Informed agreement are often afforded to adult gatekeepers, yet not necessarily extended to the children involved. This paper reports an approach to engaging with children in research, emphasising strategies to facilitate their Informed, and ongoing, Assent. As part of a research project seeking children’s perspectives of their local community, researchers developed Assent and information forms for children and young people. The aim of these forms was to promote discussion of children’s research rights, including the right to choose whether or not they engaged in the research. Within the broader research project, 130 children aged 4–12 years provided feedback about the forms and discussed how the forms influenced their participation in the research project.
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Promoting children’s Informed Assent in research participation
International Journal of Qualitative Studies in Education, 2013Co-Authors: Sue Dockett, Bob Perry, Emma KearneyAbstract:Informed agreement to participate in research is a critical element of ethical practice. When researching with children, opportunities to provide Informed agreement are often afforded to adult gatekeepers, yet not necessarily extended to the children involved. This paper reports an approach to engaging with children in research, emphasising strategies to facilitate their Informed, and ongoing, Assent. As part of a research project seeking children’s perspectives of their local community, researchers developed Assent and information forms for children and young people. The aim of these forms was to promote discussion of children’s research rights, including the right to choose whether or not they engaged in the research. Within the broader research project, 130 children aged 4–12 years provided feedback about the forms and discussed how the forms influenced their participation in the research project.
Kathleen M. Mazor - One of the best experts on this subject based on the ideXlab platform.
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Development and evaluation of a web-based Assent for adolescents considering an HIV vaccine trial
AIDS care, 2015Co-Authors: Diane R. Blake, Celeste A. Lemay, Margaret H. Kearney, Louise Maranda, J. Dennis Fortenberry, Kathleen M. MazorAbstract:HIV vaccine trials with minors will likely require parental permission and Informed Assent from adolescents. For this to be a valid process, the information needs to be presented in a manner that promotes adolescent comprehension. Previous studies suggest that adolescent comprehension of Assent is often insufficient. We developed an interactive web-based Assent that included interspersed quiz questions for a hypothetical HIV vaccine trial. Efficacy of the web-based Assent was compared to a standard paper Assent with and without interspersed questions. One hundred twenty teen participants, ages 15-17 years, from five community organizations were randomized to self-administered web-based Assent (n=60) or investigator-administered paper Assent with (n=29) or without (n=31) interspersed quiz questions. After reviewing the Assent, participants completed a 27-item comprehension test. Comprehension scores were compared between groups. The mean number of correctly answered questions were 21.2 for the full paper group and 21.1 for the web-based group (t118=-0.08, p=0.94). Scores were 20.2 for the paper without interspersed questions sub-group and 22.1 for the paper with interspersed questions sub-group (t58=1.96, p=0.055). Participants in the web-based group performed as well on the comprehension test as those in the paper group, and those in the paper with questions sub-group performed better than those in the paper without questions sub-group, suggesting that interspersed quiz questions may improve understanding of a traditional paper Assent. The minimal investigator time and standardized administration of the web-based Assent as well as ability to tailor the Assent discussion to topics identified by incorrect comprehension test responses are advantages worthy of further investigation.
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Adolescents' understanding of research concepts: a focus group study.
Archives of pediatrics & adolescent medicine, 2011Co-Authors: Diane R. Blake, Celeste A. Lemay, Margaret H. Kearney, Kathleen M. MazorAbstract:Objective To identify ways to improve adolescents' understanding of Informed Assent by exploring adolescent comprehension of concepts common to all clinical trials as well as those specific to a human immunodeficiency virus vaccine trial. Design Qualitative descriptive study. Setting Community-based organizations. Participants Healthy adolescents aged 15 to 17 years in 8 focus groups. Intervention Focus groups were conducted using a semistructured interview guide. Digital recordings of the groups were transcribed verbatim. Outcome Measure Textual data were categorized by 2 investigators using directed qualitative content analysis techniques. Major themes and subthemes were identified, and representative quotes were selected. Results The general research concepts that were most difficult for teens to understand were placebo and randomization. The most difficult vaccine trial concepts were how a vaccine works and that a vaccine is used for prevention rather than treatment. The most difficult human immunodeficiency virus vaccine–specific trial concept was that standard human immunodeficiency virus antibody tests might provide a false-positive result for participants receiving the test vaccine. Focus group participants wanted to be Informed about adverse effects, trial procedures, and whether previous research had been performed before making a decision about trial participation. Conclusions Many clinical trial concepts were difficult for teens to understand. Attention needs to be directed toward developing effective ways to explain these concepts to adolescents participating in future human immunodeficiency virus vaccine and other clinical trials.
Celine Murrin - One of the best experts on this subject based on the ideXlab platform.
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Development and validity testing of the Adolescent Health Literacy Questionnaire (AHLQ): Protocol for a mixed methods study within the Irish school setting.
BMJ open, 2020Co-Authors: Ailbhe Spillane, Sarahjane Belton, Clare M. Mcdermott, Johann Issartel, Richard H. Osborne, Shandell Elmer, Celine MurrinAbstract:Introduction Health literacy research has focused predominantly on the adult population, and much less is understood about this concept from an adolescent perspective. The tools currently available to measure adolescent health literacy have been adapted from adult versions. This limits their applicability to young people because of the developmental characteristics that impact on adolescents’ behaviour, including impulse control and judgement skills. This protocol describes the intended development and validity testing of a questionnaire to measure health literacy in adolescents. Methods and analysis This protocol describes this mixed methods study that has three phases: the first phase will involve grounded research with adolescents using qualitative group interviews, co-design and concept mapping workshops to understand what health and healthy behaviours mean to adolescents and to explore their health literacy needs and the potential domains for the questionnaire. The draft health literacy domains identified will be presented to the youth advisory panel, and the questionnaire will be altered based on their feedback. Cognitive pretesting of the questionnaire items will also be conducted. Phase 2 will involve piloting the questionnaire to a two-stage random sample of young people in five urban and rural schools in Ireland. Test–retest reliability will be conducted using Pearson correlation coefficient. Confirmatory factor analysis will also be conducted to analyse the psychometric properties of the questionnaire. Phase 3 will involve the questionnaire being rolled out to a nationally representative sample of adolescents (n=6052) in Ireland to assess their levels of health literacy. Ethics and dissemination Ethical approval to conduct this study has been granted from the University College Dublin Human Research Ethics Committee – Sciences (LS-20–08). Informed Assent from adolescents and Informed consent from parents/guardians will be sought. The findings of this research will be disseminated at national and international conferences, as well as through publication in peer-reviewed journals.