The Experts below are selected from a list of 315 Experts worldwide ranked by ideXlab platform
Syunichirou Oshima - One of the best experts on this subject based on the ideXlab platform.
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effect of total replacement of dietary fish Meal by low fluoride Krill euphausia superba Meal on growth performance of rainbow trout oncorhynchus mykiss in fresh water
Aquaculture, 2007Co-Authors: Bunji Yoshitomi, Masatoshi Aoki, Syunichirou OshimaAbstract:Abstract This study aimed to totally replace fish Meal (FM) in diets by low fluoride Krill ( Euphausia superba ) Meal (LFK). LFK was prepared by removing exoskeletons from dried whole Krill to give a fluoride content of approximately one-fourth of Krill Meal (KM) at 230 ppm for LFK and 870 ppm for KM. Experimental diets replaced FM with LFK at the replacement proportions of 0.0%, 7.7%, 15.4%, 30.8%, 46.2% and 100.0% (control, LFK7, LFK15, LFK30, LFK46 and LFK100) and were fed to groups of rainbow trout ( Oncorhynchus mykiss ) in duplicate for 95 days in fresh water and growth was observed. In all experimental groups, feed intake, feed efficiency, specific growth rate and hepatosomatic index were unchanged compared with fish fed the control diet ( P
Inge Bruheim - One of the best experts on this subject based on the ideXlab platform.
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Prospective, randomized, double-blinded, placebo-controlled study on safety and tolerability of the Krill powder product in overweight subjects with moderately elevated blood pressure
Lipids in Health and Disease, 2018Co-Authors: Essi Sarkkinen, Markku J. Savolainen, Jyrki Taurio, Tuuli Marvola, Inge BruheimAbstract:Background Krill powder is rich in bioactive ingredients such as eicosapentaenoic acid (EPA), docosahexaenoic acid (DHA), phospholipids, protein and astaxanthin. Containing dominantly EPA, it is considered to be effective in lowering lipids, foremost serum triglycerides and LDL cholesterol. Krill-derived protein hydrolysates/peptides may have positive effect on blood pressure and astaxanthin has anti-oxidative and anti-inflammatory properties. Thus, Krill powder has a lot of potential in improving lipid and metabolic profile and reinforcing the activity of the antioxidant system. However, randomized clinical trials on Krill powder are scarce and systematic data of Krill Meal on human safety is limited. Some of the earlier studies have reported several, non-serious adverse events, mostly related to gastrointestinal tract, but systematic sufficiently powered study on safety is lacking. The aim of this study was to collect data on safety and tolerability of Krill powder in humans and simultaneously gain efficacy data by measuring the risk factors for cardiovascular disease.
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Bioavailability of fatty acids from Krill oil, Krill Meal and fish oil in healthy subjects–a randomized, single-dose, cross-over trial
Lipids in Health and Disease, 2015Co-Authors: Anton Kohler, Essi Sarkkinen, Niina Tapola, Tarja Niskanen, Inge BruheimAbstract:Background Krill contains two marine omega-3 polyunsaturated fatty acids, eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), mainly bound in phospholipids. Typical products from Krill are Krill oil and Krill Meal. Fish oils contain EPA and DHA predominantly bound in triglycerides. The difference in the chemical binding of EPA and DHA has been suggested to affect their bioavailability, but little is known on bioavailability of EPA and DHA in Krill Meal. This study was undertaken to compare the acute bioavailability of two Krill products, Krill oil and Krill Meal, with fish oil in healthy subjects.
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bioavailability of fatty acids from Krill oil Krill Meal and fish oil in healthy subjects a randomized single dose cross over trial
Lipids in Health and Disease, 2015Co-Authors: Anton Kohler, Essi Sarkkinen, Niina Tapola, Tarja Niskanen, Inge BruheimAbstract:Background: Krill contains two marine omega-3 polyunsaturated fatty acids, eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), mainly bound in phospholipids. Typical products from Krill are Krill oil and Krill Meal. Fish oils contain EPA and DHA predominantly bound in triglycerides. The difference in the chemical binding of EPA and DHA has been suggested to affect their bioavailability, but little is known on bioavailability of EPA and DHA in Krill Meal. This study was undertaken to compare the acute bioavailability of two Krill products, Krill oil and Krill Meal, with fish oil in healthy subjects. Methods: A randomized, single-dose, single-blind, cross-over, active-reference trial was conducted in 15 subjects, who ingested Krill oil, Krill Meal and fish oil, each containing approx. 1 700 mg EPA and DHA. Fatty acid compositions of plasma triglycerides and phospholipids were measured repeatedly for 72 hours. The primary efficacy analysis was based on the 72 hour incremental area under the curve (iAUC) of EPA and DHA in plasma phospholipid fatty acids. Results: A larger iAUC for EPA and DHA in plasma phospholipid fatty acids was detected after Krill oil (mean 89.08± 33.36% × h) than after Krill Meal (mean 44.97±18.07% x h, p <0.001) or after fish oil (mean 59.15±22.22% × h, p=0.003). Mean iAUC’s after Krill Meal and after fish oil were not different. A large inter-individual variability in response was observed. Conclusion: EPA and DHA in Krill oil had a higher 72-hour bioavailability than in Krill Meal or fish oil. Our finding that bioavailabilities of EPA and DHA in Krill Meal and fish oil were not different argues against the interpretation that phospholipids are better absorbed than triglycerides. Longer-term studies using a parameter reflecting tissue fatty acid composition, like erythrocyte EPA plus DHA are needed. Trial registration: NCT02089165
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bioavailability of fatty acids from Krill oil Krill Meal and fish oil in healthy subjects a randomized single dose cross over trial
Lipids in Health and Disease, 2015Co-Authors: Anton Kohler, Essi Sarkkinen, Niina Tapola, Tarja Niskanen, Inge BruheimAbstract:Background Krill contains two marine omega-3 polyunsaturated fatty acids, eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), mainly bound in phospholipids. Typical products from Krill are Krill oil and Krill Meal. Fish oils contain EPA and DHA predominantly bound in triglycerides. The difference in the chemical binding of EPA and DHA has been suggested to affect their bioavailability, but little is known on bioavailability of EPA and DHA in Krill Meal. This study was undertaken to compare the acute bioavailability of two Krill products, Krill oil and Krill Meal, with fish oil in healthy subjects.
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Bioavailability of fatty acids from Krill oil, Krill Meal and fish oil in healthy subjects–a randomized, single-dose, cross-over trial
Lipids in Health and Disease, 2015Co-Authors: Anton Kohler, Essi Sarkkinen, Niina Tapola, Tarja Niskanen, Inge BruheimAbstract:Background Krill contains two marine omega-3 polyunsaturated fatty acids, eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), mainly bound in phospholipids. Typical products from Krill are Krill oil and Krill Meal. Fish oils contain EPA and DHA predominantly bound in triglycerides. The difference in the chemical binding of EPA and DHA has been suggested to affect their bioavailability, but little is known on bioavailability of EPA and DHA in Krill Meal. This study was undertaken to compare the acute bioavailability of two Krill products, Krill oil and Krill Meal, with fish oil in healthy subjects. Methods A randomized, single-dose, single-blind, cross-over, active-reference trial was conducted in 15 subjects, who ingested Krill oil, Krill Meal and fish oil, each containing approx. 1 700 mg EPA and DHA. Fatty acid compositions of plasma triglycerides and phospholipids were measured repeatedly for 72 hours. The primary efficacy analysis was based on the 72 hour incremental area under the curve (iAUC) of EPA and DHA in plasma phospholipid fatty acids. Results A larger iAUC for EPA and DHA in plasma phospholipid fatty acids was detected after Krill oil (mean 89.08 ± 33.36% × h) than after Krill Meal (mean 44.97 ± 18.07% x h, p
Changlin Liu - One of the best experts on this subject based on the ideXlab platform.
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effect of dietary antarctic Krill Meal on growth performance muscle proximate composition and antioxidative capacity of juvenile spotted halibut verasper variegatus
Journal of The World Aquaculture Society, 2018Co-Authors: Junli Yan, Qing Chang, Siqing Chen, Zhenjie Wang, Changlin LiuAbstract:A 7-wk feeding trial was conducted to evaluate the effects of dietary Antarctic Krill Meal (AKM) on the growth performance, proximate composition of muscles, and antioxidative capacity of juvenile spotted halibut. Six diets were formulated to contain about 50% protein and 8% lipid. A control diet (R0) without AKM and the other five diets with 8.1, 16.2, 24.3, 32.4, and 42.5% AKM supplementation (R10–50) to replace 10, 20, 30, 40, and 50% fishMeal protein were used to feed to juvenile spotted halibut. The juveniles were fed with each diet using three replicates and cultivated in the indoor culture system. Results showed that the specific growth rate, feed intake, and protein efficiency ratio in the R30 and R40 groups were significantly higher than that in other groups (P < 0.05). Survival rate in the R50 group was significantly lower compared with the R0 group and the other four AKM supplementation groups. Moreover, the rising AKM levels in diets had significant effects on the chemical composition of juvenile spotted halibut, showing significantly decreased contents of crude protein, but increased lipid and ash contents (P < 0.05). The total superoxide dismutase activity and catalase activity of serum and liver in AKM groups were significantly higher than those in the control group (P < 0.05). In contrast, the contents of malondialdehyde in serum and liver were significantly lower compared with the control group. These findings illustrate that a moderate AKM level in diets can significantly improve the growth performance, feed utilization, and antioxidative capacity in juvenile spotted halibut, which support the finding that AKM may be used as a good protein source for halibut in the aquafeed industry.
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Effect of Dietary Antarctic Krill Meal on Growth Performance, Muscle Proximate Composition, and Antioxidative Capacity of Juvenile Spotted Halibut, Verasper variegatus
Journal of The World Aquaculture Society, 2017Co-Authors: Junli Yan, Qing Chang, Siqing Chen, Zhenjie Wang, Changlin LiuAbstract:A 7-wk feeding trial was conducted to evaluate the effects of dietary Antarctic Krill Meal (AKM) on the growth performance, proximate composition of muscles, and antioxidative capacity of juvenile spotted halibut. Six diets were formulated to contain about 50% protein and 8% lipid. A control diet (R0) without AKM and the other five diets with 8.1, 16.2, 24.3, 32.4, and 42.5% AKM supplementation (R10–50) to replace 10, 20, 30, 40, and 50% fishMeal protein were used to feed to juvenile spotted halibut. The juveniles were fed with each diet using three replicates and cultivated in the indoor culture system. Results showed that the specific growth rate, feed intake, and protein efficiency ratio in the R30 and R40 groups were significantly higher than that in other groups (P
Junli Yan - One of the best experts on this subject based on the ideXlab platform.
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effect of dietary antarctic Krill Meal on growth performance muscle proximate composition and antioxidative capacity of juvenile spotted halibut verasper variegatus
Journal of The World Aquaculture Society, 2018Co-Authors: Junli Yan, Qing Chang, Siqing Chen, Zhenjie Wang, Changlin LiuAbstract:A 7-wk feeding trial was conducted to evaluate the effects of dietary Antarctic Krill Meal (AKM) on the growth performance, proximate composition of muscles, and antioxidative capacity of juvenile spotted halibut. Six diets were formulated to contain about 50% protein and 8% lipid. A control diet (R0) without AKM and the other five diets with 8.1, 16.2, 24.3, 32.4, and 42.5% AKM supplementation (R10–50) to replace 10, 20, 30, 40, and 50% fishMeal protein were used to feed to juvenile spotted halibut. The juveniles were fed with each diet using three replicates and cultivated in the indoor culture system. Results showed that the specific growth rate, feed intake, and protein efficiency ratio in the R30 and R40 groups were significantly higher than that in other groups (P < 0.05). Survival rate in the R50 group was significantly lower compared with the R0 group and the other four AKM supplementation groups. Moreover, the rising AKM levels in diets had significant effects on the chemical composition of juvenile spotted halibut, showing significantly decreased contents of crude protein, but increased lipid and ash contents (P < 0.05). The total superoxide dismutase activity and catalase activity of serum and liver in AKM groups were significantly higher than those in the control group (P < 0.05). In contrast, the contents of malondialdehyde in serum and liver were significantly lower compared with the control group. These findings illustrate that a moderate AKM level in diets can significantly improve the growth performance, feed utilization, and antioxidative capacity in juvenile spotted halibut, which support the finding that AKM may be used as a good protein source for halibut in the aquafeed industry.
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Effect of Dietary Antarctic Krill Meal on Growth Performance, Muscle Proximate Composition, and Antioxidative Capacity of Juvenile Spotted Halibut, Verasper variegatus
Journal of The World Aquaculture Society, 2017Co-Authors: Junli Yan, Qing Chang, Siqing Chen, Zhenjie Wang, Changlin LiuAbstract:A 7-wk feeding trial was conducted to evaluate the effects of dietary Antarctic Krill Meal (AKM) on the growth performance, proximate composition of muscles, and antioxidative capacity of juvenile spotted halibut. Six diets were formulated to contain about 50% protein and 8% lipid. A control diet (R0) without AKM and the other five diets with 8.1, 16.2, 24.3, 32.4, and 42.5% AKM supplementation (R10–50) to replace 10, 20, 30, 40, and 50% fishMeal protein were used to feed to juvenile spotted halibut. The juveniles were fed with each diet using three replicates and cultivated in the indoor culture system. Results showed that the specific growth rate, feed intake, and protein efficiency ratio in the R30 and R40 groups were significantly higher than that in other groups (P
Bunji Yoshitomi - One of the best experts on this subject based on the ideXlab platform.
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Effect of dietary fluoride derived from Antarctic Krill (Euphausia superba) Meal on growth of yellowtail (Seriola quinqueradiata)
Chemosphere, 2011Co-Authors: Bunji Yoshitomi, Ichiro NaganoAbstract:Abstract Yellowtail ( Seriola quinqueradiata ) is the most important cultured marine fish in Japan. Dietary fish Meal for yellowtail in aquaculture was replaced with 0.0%, 15.4% and 100.0% Antarctic Krill Meal (KM0, KM15, and KM100) and with 0.0%, 15.4%, and 100.0% low-fluoride Krill Meal (LFK0, LFK15 and LFK100). The fish was fed to duplicate fish groups for 92 d (KM trial) or 75 d (LFK trial), and fish growth was monitored. Dietary fluoride (F − ) concentrations (mg kg −1 ) were 110, 160, and 580 (KM0, KM15, and KM100, respectively) and 98, 120, and 190 (LFK0, LFK15, and LFK100, respectively). The growth during the experimental period, weight gain, feed intake, specific growth rate, and feed efficiency in fish fed the KM100 diet were markedly lower than the other experimental groups, which showed no marked differences in growth performance. After the experiment, dorsal muscle fluoride concentrations in each group were below the detectable limit (1 mg kg −1 ), but vertebral bone fluoride concentrations increased with increasing proportion of KM to 655 (KM0), 870 (KM15), and 2150 (KM100) mg kg −1 . With increasing LFK in the feed, vertebral bone fluoride concentrations (mg kg −1 ) increased slightly from 500 (LFK0) to 655 (LFK15), and 695 (LFK100). No histopathological changes were detected in the liver tissue in any experimental group. It has been reported that the fluoride bioavailability was reduced with increasing water hardness, however, the dietary fluoride derived from KM exoskeleton accumulates in vertebral bones of marine fish with growth inhibition, as has already been shown for freshwater fish. Vertebral bone fluoride concentrations in two Krill-eating Antarctic marine fish in the wild were 33 000 mg kg −1 ( Champsocephalus gunnari ) and 15 000 mg kg −1 ( Notothenia rossii ), but they did not show any adverse effect of growth. Therefore, fish bone fluoride accumulation apparently depends on fish species rather than the salinity of the habitat. Consequently, Krill exoskeleton must be removed during the processing of Antarctic Krill if indeed these Krill are to be used as fish feed. However, LFK can completely replace dietary fish Meal without apparent adverse effects.
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effect of total replacement of dietary fish Meal by low fluoride Krill euphausia superba Meal on growth performance of rainbow trout oncorhynchus mykiss in fresh water
Aquaculture, 2007Co-Authors: Bunji Yoshitomi, Masatoshi Aoki, Syunichirou OshimaAbstract:Abstract This study aimed to totally replace fish Meal (FM) in diets by low fluoride Krill ( Euphausia superba ) Meal (LFK). LFK was prepared by removing exoskeletons from dried whole Krill to give a fluoride content of approximately one-fourth of Krill Meal (KM) at 230 ppm for LFK and 870 ppm for KM. Experimental diets replaced FM with LFK at the replacement proportions of 0.0%, 7.7%, 15.4%, 30.8%, 46.2% and 100.0% (control, LFK7, LFK15, LFK30, LFK46 and LFK100) and were fed to groups of rainbow trout ( Oncorhynchus mykiss ) in duplicate for 95 days in fresh water and growth was observed. In all experimental groups, feed intake, feed efficiency, specific growth rate and hepatosomatic index were unchanged compared with fish fed the control diet ( P
