The Experts below are selected from a list of 645543 Experts worldwide ranked by ideXlab platform
Ajay Kumar Chinnam - One of the best experts on this subject based on the ideXlab platform.
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anomalous behaviour of cis bicyclo 3 3 0 octane 3 7 dione and its derivatives during twofold fischer indole cyclization using low melting mixtures
ChemInform, 2014Co-Authors: Sambasivarao Kotha, Ajay Kumar ChinnamAbstract:Fischer indole cyclization in a low melting mixture of L-Tartaric Acid and N,N′-dimethylurea provides the expected isomer (III) together with unexpected high amounts of the unusual isomer (IV).
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anomalous behaviour of cis bicyclo 3 3 0 octane 3 7 dione and its derivatives during twofold fischer indole cyclization using low melting mixtures
Synthesis, 2013Co-Authors: Sambasivarao Kotha, Ajay Kumar ChinnamAbstract:We have developed an efficient method for the synthesis of the pentaleno[2,1- b :5,4- b ′]diindole and pentaleno[2,1- b :5,6- b ′]diindole skeletons via twofold Fischer indole cyclization. In this new procedure, cis -bicyclo[3.3.0]octane-3,7-dione on treatment with 1-methyl-1-phenylhydrazine in the presence of a low-melting mixture of l -(+)-tartaric Acid and N , N ′-dimethylurea at 70 °C undergoes a twofold Fischer indole cyclization to deliver the unusual C s -symmetrical product pentaleno[2,1- b :5,6- b ′]diindole, along with the expected C 2 -symmetrical pentaleno[2,1- b :5,4- b ′]diindole product.
Sangram Gore - One of the best experts on this subject based on the ideXlab platform.
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synthesis of substituted hydantoins in low melting mixtures
Chemical Communications, 2013Co-Authors: Sangram Gore, Kiran Chinthapally, Sundarababu Baskaran, Burkhard KönigAbstract:A novel domino synthesis of 1,3,5-trisubstituted hydantoin derivatives has been developed in low melting L-(+)-tartaric Acid–DMU melt mixtures. The functionalized hydantoins are obtained in good yields from β,γ-unsaturated ketoAcids and urea under environmentally benign and simple reaction conditions.
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synthesis of pyrimidopyrimidinediones in a deep eutectic reaction mixture
ChemInform, 2013Co-Authors: Sangram Gore, Sundarababu Baskaran, Burkhard KoenigAbstract:A novel and general synthesis of title compounds is developed employing a low melting L-(+)-tartaric Acid—N,N-dimethylurea mixture as reaction medium.
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synthesis of pyrimidopyrimidinediones in a deep eutectic reaction mixture
Advanced Synthesis & Catalysis, 2012Co-Authors: Sangram Gore, Sundarababu Baskaran, Burkhard KoenigAbstract:An efficient and general synthesis of hexahydropyrimidopyrimidinediones has been developed employing a low melting L-(+)-tartaric Acid-dimethylurea mixture as reaction medium. The melt acts at the same time as solvent, catalyst and reactant. Functionalized hexahydropyrimidopyrimidinediones are obtained in good to excellent yields after simple work-up.
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efficient synthesis of 3 4 dihydropyrimidin 2 ones in low melting tartaric Acid urea mixtures
Green Chemistry, 2011Co-Authors: Sangram Gore, Sundarababu Baskaran, Burkhard KoenigAbstract:A general, efficient and green method for the synthesis of dihydropyrimidinones is described under mild conditions employing low melting mixtures of L-(+)-tartaric Acid and urea derivatives as a novel reaction medium. The melt plays a triple role: as solvent, as catalyst and as reactant, furnishing highly functionalized dihydropyrimidinones in good to excellent yields.
Burkhard Koenig - One of the best experts on this subject based on the ideXlab platform.
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synthesis of pyrimidopyrimidinediones in a deep eutectic reaction mixture
ChemInform, 2013Co-Authors: Sangram Gore, Sundarababu Baskaran, Burkhard KoenigAbstract:A novel and general synthesis of title compounds is developed employing a low melting L-(+)-tartaric Acid—N,N-dimethylurea mixture as reaction medium.
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synthesis of pyrimidopyrimidinediones in a deep eutectic reaction mixture
Advanced Synthesis & Catalysis, 2012Co-Authors: Sangram Gore, Sundarababu Baskaran, Burkhard KoenigAbstract:An efficient and general synthesis of hexahydropyrimidopyrimidinediones has been developed employing a low melting L-(+)-tartaric Acid-dimethylurea mixture as reaction medium. The melt acts at the same time as solvent, catalyst and reactant. Functionalized hexahydropyrimidopyrimidinediones are obtained in good to excellent yields after simple work-up.
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efficient synthesis of 3 4 dihydropyrimidin 2 ones in low melting tartaric Acid urea mixtures
Green Chemistry, 2011Co-Authors: Sangram Gore, Sundarababu Baskaran, Burkhard KoenigAbstract:A general, efficient and green method for the synthesis of dihydropyrimidinones is described under mild conditions employing low melting mixtures of L-(+)-tartaric Acid and urea derivatives as a novel reaction medium. The melt plays a triple role: as solvent, as catalyst and as reactant, furnishing highly functionalized dihydropyrimidinones in good to excellent yields.
Sambasivarao Kotha - One of the best experts on this subject based on the ideXlab platform.
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anomalous behaviour of cis bicyclo 3 3 0 octane 3 7 dione and its derivatives during twofold fischer indole cyclization using low melting mixtures
ChemInform, 2014Co-Authors: Sambasivarao Kotha, Ajay Kumar ChinnamAbstract:Fischer indole cyclization in a low melting mixture of L-Tartaric Acid and N,N′-dimethylurea provides the expected isomer (III) together with unexpected high amounts of the unusual isomer (IV).
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anomalous behaviour of cis bicyclo 3 3 0 octane 3 7 dione and its derivatives during twofold fischer indole cyclization using low melting mixtures
Synthesis, 2013Co-Authors: Sambasivarao Kotha, Ajay Kumar ChinnamAbstract:We have developed an efficient method for the synthesis of the pentaleno[2,1- b :5,4- b ′]diindole and pentaleno[2,1- b :5,6- b ′]diindole skeletons via twofold Fischer indole cyclization. In this new procedure, cis -bicyclo[3.3.0]octane-3,7-dione on treatment with 1-methyl-1-phenylhydrazine in the presence of a low-melting mixture of l -(+)-tartaric Acid and N , N ′-dimethylurea at 70 °C undergoes a twofold Fischer indole cyclization to deliver the unusual C s -symmetrical product pentaleno[2,1- b :5,6- b ′]diindole, along with the expected C 2 -symmetrical pentaleno[2,1- b :5,4- b ′]diindole product.
Guoxin Song - One of the best experts on this subject based on the ideXlab platform.
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correction a universal strategy for visual chiral recognition of α amino Acids with l tartaric Acid capped gold nanoparticles as colorimetric probes
Analyst, 2016Co-Authors: Guoxin Song, Fulin ZhouAbstract:The ability to recognize and quantify the chirality of alpha-amino Acids constitutes the basis of many critical areas for specific targeting in drug development and metabolite probing. It is still challenging to conveniently distinguish the enantiomer of amino Acids largely due to the lack of a universal and simple strategy. In this work, we report a strategy for the visual recognition of α-amino Acids. It is based on the chirality of L-Tartaric Acid-capped gold nanoparticles (L-TA-capped AuNPs, ca. 13 nm in diameter). All of 19 right-handed α-amino Acids can induce a red-to-blue color change of L-TA-capped AuNP solution, whereas all of the left-handed amino Acids (except cysteine) cannot. The chiral recognition can be achieved by the naked eye and a simple spectrophotometer. This method does not require complicated chiral modification, and excels through its low-cost, good availability of materials and its simplicity. Another notable feature of this method is its high generality, and this method can discriminate almost all native α-amino Acid enantiomers. This versatile method could be potentially used for high-throughput chiral recognition of amino Acids.
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visual chiral recognition of mandelic Acid enantiomers with l tartaric Acid capped gold nanoparticles as colorimetric probes
Sensors and Actuators B-chemical, 2015Co-Authors: Guoxin SongAbstract:Abstract We report a method for visual differentiation between the l - and d -forms of mandelic Acid (MA). It is based on the chirality of l -tartaric Acid-capped gold nanoparticles ( l -TA-capped AuNPs, ca. 13 nm in diameter) that can be used as chiral selector for l - and d -forms of MA. On addition of l -MA to a solution of the l -TA-capped AuNPs, a color change from red to blue can be seen, while no color change is found on addition of d -MA. The chiral assay can be used to determine the enantiomeric excess of l -MA in the range from −100% to 100%. The effect can be detected with bare eyes and quantified by spectrophotometry. Notably, this method does not require the complicated chiral modification. The method excels by its sensitivity, low cost, good availability of materials, and its simplicity.
