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J J Verlaan - One of the best experts on this subject based on the ideXlab platform.

  • Extensive thoracolumbosacral vertebral osteomyelitis after Lemierre Syndrome
    European Spine Journal, 2015
    Co-Authors: D H R Kempen, A I M Hoepelman, F C Oner, M. Dijk, J J Verlaan
    Abstract:

    Purpose To present a unique case of multilevel vertebral osteomyelitis after Lemierre Syndrome. Methods A previously healthy 27-year-old man presented in the Emergency Department in septic shock because of Lemierre Syndrome for which he was subsequently treated with intravenous benzylpenicillin for 2 months. Two and a half months later, the patient was readmitted with severe back pain without neurological deficits or fever. Imaging revealed an extensive vertebral osteomyelitis of the complete thoracic, lumbar and sacral spine. Results Although the blood cultures obtained at the initial admission for Lemierre Syndrome revealed Fusobacterium species and Streptococcus milleri , the cultures from the spinal biopsies remained negative. Histology of the spinal biopsies showed a purulent sclerosing osteomyelitis. The patient was successfully treated with intravenous piperacillin and tazobactam. Despite persisting back pain, no recurrence of infection was seen at 3 years of follow-up. Conclusion Lemierre Syndrome and an extensive thoracolumbosacral vertebral osteomyelitis are rare but serious infections. Clinicians must maintain a high index of suspicion for infectious metastases leading to vertebral osteomyelitis when a patient presents with back pain after an episode of life-threatening septicaemia caused by Lemierre Syndrome.

  • extensive thoracolumbosacral vertebral osteomyelitis after Lemierre Syndrome
    European Spine Journal, 2015
    Co-Authors: D H R Kempen, M Van Dijk, A I M Hoepelman, F C Oner, J J Verlaan
    Abstract:

    Purpose To present a unique case of multilevel vertebral osteomyelitis after Lemierre Syndrome.

  • Extensive thoracolumbosacral vertebral osteomyelitis after Lemierre Syndrome.
    European spine journal : official publication of the European Spine Society the European Spinal Deformity Society and the European Section of the Cerv, 2014
    Co-Authors: D H R Kempen, M Van Dijk, A I M Hoepelman, F C Oner, J J Verlaan
    Abstract:

    To present a unique case of multilevel vertebral osteomyelitis after Lemierre Syndrome. A previously healthy 27-year-old man presented in the Emergency Department in septic shock because of Lemierre Syndrome for which he was subsequently treated with intravenous benzylpenicillin for 2 months. Two and a half months later, the patient was readmitted with severe back pain without neurological deficits or fever. Imaging revealed an extensive vertebral osteomyelitis of the complete thoracic, lumbar and sacral spine. Although the blood cultures obtained at the initial admission for Lemierre Syndrome revealed Fusobacterium species and Streptococcus milleri, the cultures from the spinal biopsies remained negative. Histology of the spinal biopsies showed a purulent sclerosing osteomyelitis. The patient was successfully treated with intravenous piperacillin and tazobactam. Despite persisting back pain, no recurrence of infection was seen at 3 years of follow-up. Lemierre Syndrome and an extensive thoracolumbosacral vertebral osteomyelitis are rare but serious infections. Clinicians must maintain a high index of suspicion for infectious metastases leading to vertebral osteomyelitis when a patient presents with back pain after an episode of life-threatening septicaemia caused by Lemierre Syndrome.

D H R Kempen - One of the best experts on this subject based on the ideXlab platform.

  • Extensive thoracolumbosacral vertebral osteomyelitis after Lemierre Syndrome
    European Spine Journal, 2015
    Co-Authors: D H R Kempen, A I M Hoepelman, F C Oner, M. Dijk, J J Verlaan
    Abstract:

    Purpose To present a unique case of multilevel vertebral osteomyelitis after Lemierre Syndrome. Methods A previously healthy 27-year-old man presented in the Emergency Department in septic shock because of Lemierre Syndrome for which he was subsequently treated with intravenous benzylpenicillin for 2 months. Two and a half months later, the patient was readmitted with severe back pain without neurological deficits or fever. Imaging revealed an extensive vertebral osteomyelitis of the complete thoracic, lumbar and sacral spine. Results Although the blood cultures obtained at the initial admission for Lemierre Syndrome revealed Fusobacterium species and Streptococcus milleri , the cultures from the spinal biopsies remained negative. Histology of the spinal biopsies showed a purulent sclerosing osteomyelitis. The patient was successfully treated with intravenous piperacillin and tazobactam. Despite persisting back pain, no recurrence of infection was seen at 3 years of follow-up. Conclusion Lemierre Syndrome and an extensive thoracolumbosacral vertebral osteomyelitis are rare but serious infections. Clinicians must maintain a high index of suspicion for infectious metastases leading to vertebral osteomyelitis when a patient presents with back pain after an episode of life-threatening septicaemia caused by Lemierre Syndrome.

  • extensive thoracolumbosacral vertebral osteomyelitis after Lemierre Syndrome
    European Spine Journal, 2015
    Co-Authors: D H R Kempen, M Van Dijk, A I M Hoepelman, F C Oner, J J Verlaan
    Abstract:

    Purpose To present a unique case of multilevel vertebral osteomyelitis after Lemierre Syndrome.

  • Extensive thoracolumbosacral vertebral osteomyelitis after Lemierre Syndrome.
    European spine journal : official publication of the European Spine Society the European Spinal Deformity Society and the European Section of the Cerv, 2014
    Co-Authors: D H R Kempen, M Van Dijk, A I M Hoepelman, F C Oner, J J Verlaan
    Abstract:

    To present a unique case of multilevel vertebral osteomyelitis after Lemierre Syndrome. A previously healthy 27-year-old man presented in the Emergency Department in septic shock because of Lemierre Syndrome for which he was subsequently treated with intravenous benzylpenicillin for 2 months. Two and a half months later, the patient was readmitted with severe back pain without neurological deficits or fever. Imaging revealed an extensive vertebral osteomyelitis of the complete thoracic, lumbar and sacral spine. Although the blood cultures obtained at the initial admission for Lemierre Syndrome revealed Fusobacterium species and Streptococcus milleri, the cultures from the spinal biopsies remained negative. Histology of the spinal biopsies showed a purulent sclerosing osteomyelitis. The patient was successfully treated with intravenous piperacillin and tazobactam. Despite persisting back pain, no recurrence of infection was seen at 3 years of follow-up. Lemierre Syndrome and an extensive thoracolumbosacral vertebral osteomyelitis are rare but serious infections. Clinicians must maintain a high index of suspicion for infectious metastases leading to vertebral osteomyelitis when a patient presents with back pain after an episode of life-threatening septicaemia caused by Lemierre Syndrome.

Thomas Skov Randrup - One of the best experts on this subject based on the ideXlab platform.

  • Isolated Facial Vein Thrombophlebitis: A Variant of Lemierre Syndrome
    2016
    Co-Authors: Kirstine K S Karnov, Jacob Lilja-fischer, Thomas Skov Randrup
    Abstract:

    Lemierre Syndrome is a rare complication of acute tonsillitis. It is caused by the anaerobic bacterium Fu-sobacterium necrophorum and is characterized by bacteremia and septic thrombosis of the internal jug-ular vein. Dissemination of septic emboli may occur. The diagnosis can be difficult since different organs can be involved. We discuss a case of Lemierre syn-drome in a 35-year-old woman with isolated throm-bophlebitis of the facial vein and fusobacteria growth in blood culture. This case emphasizes the need for awareness of the condition. Keywords. Lemierre Syndrome; facial vein throm-bosis; Fusobacterium necrophorum; anaerobic postangi-nal sepsis. Lemierre Syndrome (LS) is a rare complication of acut

  • isolated facial vein thrombophlebitis a variant of Lemierre Syndrome
    Open Forum Infectious Diseases, 2014
    Co-Authors: Kirstine K S Karnov, J Liljafischer, Thomas Skov Randrup
    Abstract:

    Lemierre Syndrome is a rare complication of acute tonsillitis. It is caused by the anaerobic bacterium Fusobacterium necrophorum and is characterized by bacteremia and septic thrombosis of the internal jugular vein. Dissemination of septic emboli may occur. The diagnosis can be difficult since different organs can be involved. We discuss a case of Lemierre Syndrome in a 35-year-old woman with isolated thrombophlebitis of the facial vein and fusobacteria growth in blood culture. This case emphasizes the need for awareness of the condition.

A I M Hoepelman - One of the best experts on this subject based on the ideXlab platform.

  • Extensive thoracolumbosacral vertebral osteomyelitis after Lemierre Syndrome
    European Spine Journal, 2015
    Co-Authors: D H R Kempen, A I M Hoepelman, F C Oner, M. Dijk, J J Verlaan
    Abstract:

    Purpose To present a unique case of multilevel vertebral osteomyelitis after Lemierre Syndrome. Methods A previously healthy 27-year-old man presented in the Emergency Department in septic shock because of Lemierre Syndrome for which he was subsequently treated with intravenous benzylpenicillin for 2 months. Two and a half months later, the patient was readmitted with severe back pain without neurological deficits or fever. Imaging revealed an extensive vertebral osteomyelitis of the complete thoracic, lumbar and sacral spine. Results Although the blood cultures obtained at the initial admission for Lemierre Syndrome revealed Fusobacterium species and Streptococcus milleri , the cultures from the spinal biopsies remained negative. Histology of the spinal biopsies showed a purulent sclerosing osteomyelitis. The patient was successfully treated with intravenous piperacillin and tazobactam. Despite persisting back pain, no recurrence of infection was seen at 3 years of follow-up. Conclusion Lemierre Syndrome and an extensive thoracolumbosacral vertebral osteomyelitis are rare but serious infections. Clinicians must maintain a high index of suspicion for infectious metastases leading to vertebral osteomyelitis when a patient presents with back pain after an episode of life-threatening septicaemia caused by Lemierre Syndrome.

  • extensive thoracolumbosacral vertebral osteomyelitis after Lemierre Syndrome
    European Spine Journal, 2015
    Co-Authors: D H R Kempen, M Van Dijk, A I M Hoepelman, F C Oner, J J Verlaan
    Abstract:

    Purpose To present a unique case of multilevel vertebral osteomyelitis after Lemierre Syndrome.

  • Extensive thoracolumbosacral vertebral osteomyelitis after Lemierre Syndrome.
    European spine journal : official publication of the European Spine Society the European Spinal Deformity Society and the European Section of the Cerv, 2014
    Co-Authors: D H R Kempen, M Van Dijk, A I M Hoepelman, F C Oner, J J Verlaan
    Abstract:

    To present a unique case of multilevel vertebral osteomyelitis after Lemierre Syndrome. A previously healthy 27-year-old man presented in the Emergency Department in septic shock because of Lemierre Syndrome for which he was subsequently treated with intravenous benzylpenicillin for 2 months. Two and a half months later, the patient was readmitted with severe back pain without neurological deficits or fever. Imaging revealed an extensive vertebral osteomyelitis of the complete thoracic, lumbar and sacral spine. Although the blood cultures obtained at the initial admission for Lemierre Syndrome revealed Fusobacterium species and Streptococcus milleri, the cultures from the spinal biopsies remained negative. Histology of the spinal biopsies showed a purulent sclerosing osteomyelitis. The patient was successfully treated with intravenous piperacillin and tazobactam. Despite persisting back pain, no recurrence of infection was seen at 3 years of follow-up. Lemierre Syndrome and an extensive thoracolumbosacral vertebral osteomyelitis are rare but serious infections. Clinicians must maintain a high index of suspicion for infectious metastases leading to vertebral osteomyelitis when a patient presents with back pain after an episode of life-threatening septicaemia caused by Lemierre Syndrome.

F C Oner - One of the best experts on this subject based on the ideXlab platform.

  • Extensive thoracolumbosacral vertebral osteomyelitis after Lemierre Syndrome
    European Spine Journal, 2015
    Co-Authors: D H R Kempen, A I M Hoepelman, F C Oner, M. Dijk, J J Verlaan
    Abstract:

    Purpose To present a unique case of multilevel vertebral osteomyelitis after Lemierre Syndrome. Methods A previously healthy 27-year-old man presented in the Emergency Department in septic shock because of Lemierre Syndrome for which he was subsequently treated with intravenous benzylpenicillin for 2 months. Two and a half months later, the patient was readmitted with severe back pain without neurological deficits or fever. Imaging revealed an extensive vertebral osteomyelitis of the complete thoracic, lumbar and sacral spine. Results Although the blood cultures obtained at the initial admission for Lemierre Syndrome revealed Fusobacterium species and Streptococcus milleri , the cultures from the spinal biopsies remained negative. Histology of the spinal biopsies showed a purulent sclerosing osteomyelitis. The patient was successfully treated with intravenous piperacillin and tazobactam. Despite persisting back pain, no recurrence of infection was seen at 3 years of follow-up. Conclusion Lemierre Syndrome and an extensive thoracolumbosacral vertebral osteomyelitis are rare but serious infections. Clinicians must maintain a high index of suspicion for infectious metastases leading to vertebral osteomyelitis when a patient presents with back pain after an episode of life-threatening septicaemia caused by Lemierre Syndrome.

  • extensive thoracolumbosacral vertebral osteomyelitis after Lemierre Syndrome
    European Spine Journal, 2015
    Co-Authors: D H R Kempen, M Van Dijk, A I M Hoepelman, F C Oner, J J Verlaan
    Abstract:

    Purpose To present a unique case of multilevel vertebral osteomyelitis after Lemierre Syndrome.

  • Extensive thoracolumbosacral vertebral osteomyelitis after Lemierre Syndrome.
    European spine journal : official publication of the European Spine Society the European Spinal Deformity Society and the European Section of the Cerv, 2014
    Co-Authors: D H R Kempen, M Van Dijk, A I M Hoepelman, F C Oner, J J Verlaan
    Abstract:

    To present a unique case of multilevel vertebral osteomyelitis after Lemierre Syndrome. A previously healthy 27-year-old man presented in the Emergency Department in septic shock because of Lemierre Syndrome for which he was subsequently treated with intravenous benzylpenicillin for 2 months. Two and a half months later, the patient was readmitted with severe back pain without neurological deficits or fever. Imaging revealed an extensive vertebral osteomyelitis of the complete thoracic, lumbar and sacral spine. Although the blood cultures obtained at the initial admission for Lemierre Syndrome revealed Fusobacterium species and Streptococcus milleri, the cultures from the spinal biopsies remained negative. Histology of the spinal biopsies showed a purulent sclerosing osteomyelitis. The patient was successfully treated with intravenous piperacillin and tazobactam. Despite persisting back pain, no recurrence of infection was seen at 3 years of follow-up. Lemierre Syndrome and an extensive thoracolumbosacral vertebral osteomyelitis are rare but serious infections. Clinicians must maintain a high index of suspicion for infectious metastases leading to vertebral osteomyelitis when a patient presents with back pain after an episode of life-threatening septicaemia caused by Lemierre Syndrome.