The Experts below are selected from a list of 300 Experts worldwide ranked by ideXlab platform
Anca M Avram - One of the best experts on this subject based on the ideXlab platform.
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Lingual Thyroid ectopia diagnostic spect ct imaging and radioactive iodine treatment
Thyroid, 2016Co-Authors: Arpit Gandhi, Ka Kit Wong, Milton D Gross, Anca M AvramAbstract:Background: Lingual Thyroid is a rare abnormality of Thyroid development that is usually treated conservatively with levothyroxine replacement. Rarely, it becomes large enough to cause obstructive symptoms in the oral cavity, requiring definitive treatment. Patient Findings: This study reports on three patients with Lingual Thyroid treated with radioactive iodine-131 (131I) with successful radioablation of their ectopic Thyroid tissues. Measurement of 24-hour radioactive iodine uptake within Thyroidal tissues and hybrid single-photon emission computed tomography/computed tomography imaging using either iodine-123 or technetium-99m pertechnetate scans were performed in all patients demonstrating the location and size of Lingual Thyroid and absence of an orthotopic Thyroid gland. Summary: The aim of this study was to describe nonsurgical management of obstructive Lingual Thyroid tissue with 131I therapy for Lingual Thyroid radioablation. Patients were prepared with a low-iodine diet and levothyroxine withdr...
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Lingual Thyroid Ectopia: Diagnostic SPECT/CT Imaging and Radioactive Iodine Treatment
Thyroid : official journal of the American Thyroid Association, 2016Co-Authors: Arpit Gandhi, Ka Kit Wong, Milton D Gross, Anca M AvramAbstract:Background: Lingual Thyroid is a rare abnormality of Thyroid development that is usually treated conservatively with levothyroxine replacement. Rarely, it becomes large enough to cause obstructive symptoms in the oral cavity, requiring definitive treatment. Patient Findings: This study reports on three patients with Lingual Thyroid treated with radioactive iodine-131 (131I) with successful radioablation of their ectopic Thyroid tissues. Measurement of 24-hour radioactive iodine uptake within Thyroidal tissues and hybrid single-photon emission computed tomography/computed tomography imaging using either iodine-123 or technetium-99m pertechnetate scans were performed in all patients demonstrating the location and size of Lingual Thyroid and absence of an orthotopic Thyroid gland. Summary: The aim of this study was to describe nonsurgical management of obstructive Lingual Thyroid tissue with 131I therapy for Lingual Thyroid radioablation. Patients were prepared with a low-iodine diet and levothyroxine withdr...
Nestor R. Gonzalez - One of the best experts on this subject based on the ideXlab platform.
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Enlarged hemorrhagic Lingual Thyroid managed with transoral robotic surgery
Endocrine, 2021Co-Authors: Carolyn F. Filarski, Brett Levine, Anshu Buttan, Nestor R. GonzalezAbstract:Purpose Lingual Thyroid glands are rare embryologic variants of undescended tissue centered in the base of the tongue. Despite notable size, many Lingual Thyroids can be asymptomatic, though intervention is warranted for progressive or emergent symptoms. We report a rare manifestation of a hemorrhagic Lingual Thyroid addressed with both interventional radiology and robotic techniques. Methods A previously asymptomatic 41-year old female presented to the emergency department with massive hematemesis after significant binge drinking and vomiting. Emergent intubation was performed and gastroenterology workup ruled out Mallory–Weiss tears or ruptured esophageal varices. Fiberoptic laryngoscopy and imaging revealed a bleeding tongue base mass concerning for malignancy. Results Aberrant feeding vessels with identifiable blush were embolized by Neurointerventional Radiology and the patient underwent tracheostomy for airway protection. Lingual Thyroid was confirmed by biopsy and the mass was definitively resected via transoral robotic surgery. The patient had no further bleeding events and was decannulated uneventfully. Conclusions Lingual Thyroid glands can present with life-threatening hematemesis and obstruction that may masquerade as entities of vascular or neoplastic origin. Management encompasses multidisciplinary diagnostic confirmation, airway protection, and minimally invasive resection that minimizes functional morbidity.
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Enlarged hemorrhagic Lingual Thyroid managed with transoral robotic surgery
Endocrine, 2021Co-Authors: Carolyn F. Filarski, Brett Levine, Anshu Buttan, Nestor R. GonzalezAbstract:Lingual Thyroid glands are rare embryologic variants of undescended tissue centered in the base of the tongue. Despite notable size, many Lingual Thyroids can be asymptomatic, though intervention is warranted for progressive or emergent symptoms. We report a rare manifestation of a hemorrhagic Lingual Thyroid addressed with both interventional radiology and robotic techniques. A previously asymptomatic 41-year old female presented to the emergency department with massive hematemesis after significant binge drinking and vomiting. Emergent intubation was performed and gastroenterology workup ruled out Mallory–Weiss tears or ruptured esophageal varices. Fiberoptic laryngoscopy and imaging revealed a bleeding tongue base mass concerning for malignancy. Aberrant feeding vessels with identifiable blush were embolized by Neurointerventional Radiology and the patient underwent tracheostomy for airway protection. Lingual Thyroid was confirmed by biopsy and the mass was definitively resected via transoral robotic surgery. The patient had no further bleeding events and was decannulated uneventfully. Lingual Thyroid glands can present with life-threatening hematemesis and obstruction that may masquerade as entities of vascular or neoplastic origin. Management encompasses multidisciplinary diagnostic confirmation, airway protection, and minimally invasive resection that minimizes functional morbidity.
Mariacarla Moleti - One of the best experts on this subject based on the ideXlab platform.
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Thyroid cancer in Lingual Thyroid and thyroglossal duct cyst
Endocrinología Diabetes y Nutrición, 2017Co-Authors: Giacomo Carlo Sturniolo, Francesco Vermiglio, Mariacarla MoletiAbstract:Ectopy is the most common embryogenetic defect of the Thyroid gland, representing between 48 and 61% of all Thyroid dysgeneses. Persistence of Thyroid tissue in the context of a thyroglossal duct remnant and Lingual Thyroid tissue are the most common defects. Although most cases of ectopic Thyroid are asymptomatic, any disease affecting the Thyroid may potentially involve the ectopic tissue, including malignancies. The prevalence of differentiated Thyroid carcinoma in Lingual Thyroid and thyroglossal duct cyst is around 1% of patients affected with the above Thyroid ectopies. We here review the current literature concerning primary Thyroid carcinomas originating from Thyroid tissue on thyroglossal duct cysts and Lingual Thyroid.
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Differentiated Thyroid carcinoma in Lingual Thyroid
Endocrine, 2016Co-Authors: Giacomo Sturniolo, Maria Antonia Violi, Bruno Galletti, Sergio Baldari, Alfredo Campennì, Francesco Vermiglio, Mariacarla MoletiAbstract:The Lingual Thyroid is the most common form of Thyroid ectopy. The ectopic tissue may display any disease affecting the Thyroid, including malignancies, which have an estimated incidence of less than 1 %. To date only 51 cases of Lingual Thyroid cancer were reported. Analogously to what observed in orthotopic Thyroid, papillary carcinoma is the predominant histotype in Lingual Thyroid carcinoma. The higher frequency of Lingual follicular Thyroid carcinoma previously reported is possibly related to histological misclassification in some early reports, prior to the standardization of histological typing of differentiated Thyroid carcinomas. Nonetheless, the frequency of the follicular histotype is not negligible, accounting for about one-third of the reported cases. Both natural history and prognosis of Lingual Thyroid carcinoma are poorly known, likely because of the rarity of the disease and the heterogeneity in the therapeutic approach. However, among the cases more recently reported, surgical excision of the mass, either alone or followed by radioiodine ablation, is the first-line approach, with only two cases treated by radioiodine alone. The nonsignificant rate of neoplastic transformation in Lingual Thyroid should encourage efforts to obtain a widely accepted consensus for the management of this rare condition, along with standardization of either diagnostic or therapeutic handling of malignancies arising in ectopic Thyroid.
Waldemar L. Riefkohl - One of the best experts on this subject based on the ideXlab platform.
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Lingual Thyroid carcinoma with nodal metastasis.
The Laryngoscope, 2007Co-Authors: Thomas L. Kennedy, Waldemar L. RiefkohlAbstract:Objectives: To discuss treatment options and surgical management of Lingual Thyroid carcinoma with cervical metastasis. Study Design: Lingual Thyroid is relatively uncommon, and carcinoma of the Lingual Thyroid is extremely rare, with only 40 cases reported. We report a new case of a young female who presented with a cervical neck mass found to represent metastatic papillary Thyroid carcinoma. Further workup revealed the patient's only Thyroid tissue was located at the tongue base and was the site of the primary tumor. Management of Lingual Thyroid carcinoma and review of the literature is discussed. Methods: A case report and review of the literature of Lingual Thyroid carcinoma. Results: A young female presented with a left neck mass diagnosed as metastatic papillary Thyroid carcinoma. Review of the computed tomography scan of the neck revealed a tongue base mass, absence of an othotopic Thyroid gland and bilateral cervical lymphandenopathy. Bilateral selective neck dissections with removal of the tongue base lesion confirmed the diagnosis of Lingual Thyroid carcinoma with multiple left cervical nodal metastases. Conclusions: A case of Lingual papillary Thyroid carcinoma with cervical metastasis is reported. Treatment is best managed with surgical excision of all Thyroid tissue followed by radioactive iodine ablation. Surgical approaches to the tongue base need to be considered based on the size of the Lingual primary tumor and the need to address lymph node metastases gland. This is the first reported case in the literature of Lingual papillary Thyroid carcinoma presenting with cervical nodal metastasis in a female with absence of an orthotopic Thyroid gland. This is also the first report to show that papillary and not follicular cell carcinoma is the predominating histopathology in Lingual Thyroid carcinoma.
Arpit Gandhi - One of the best experts on this subject based on the ideXlab platform.
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Lingual Thyroid ectopia diagnostic spect ct imaging and radioactive iodine treatment
Thyroid, 2016Co-Authors: Arpit Gandhi, Ka Kit Wong, Milton D Gross, Anca M AvramAbstract:Background: Lingual Thyroid is a rare abnormality of Thyroid development that is usually treated conservatively with levothyroxine replacement. Rarely, it becomes large enough to cause obstructive symptoms in the oral cavity, requiring definitive treatment. Patient Findings: This study reports on three patients with Lingual Thyroid treated with radioactive iodine-131 (131I) with successful radioablation of their ectopic Thyroid tissues. Measurement of 24-hour radioactive iodine uptake within Thyroidal tissues and hybrid single-photon emission computed tomography/computed tomography imaging using either iodine-123 or technetium-99m pertechnetate scans were performed in all patients demonstrating the location and size of Lingual Thyroid and absence of an orthotopic Thyroid gland. Summary: The aim of this study was to describe nonsurgical management of obstructive Lingual Thyroid tissue with 131I therapy for Lingual Thyroid radioablation. Patients were prepared with a low-iodine diet and levothyroxine withdr...
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Lingual Thyroid Ectopia: Diagnostic SPECT/CT Imaging and Radioactive Iodine Treatment
Thyroid : official journal of the American Thyroid Association, 2016Co-Authors: Arpit Gandhi, Ka Kit Wong, Milton D Gross, Anca M AvramAbstract:Background: Lingual Thyroid is a rare abnormality of Thyroid development that is usually treated conservatively with levothyroxine replacement. Rarely, it becomes large enough to cause obstructive symptoms in the oral cavity, requiring definitive treatment. Patient Findings: This study reports on three patients with Lingual Thyroid treated with radioactive iodine-131 (131I) with successful radioablation of their ectopic Thyroid tissues. Measurement of 24-hour radioactive iodine uptake within Thyroidal tissues and hybrid single-photon emission computed tomography/computed tomography imaging using either iodine-123 or technetium-99m pertechnetate scans were performed in all patients demonstrating the location and size of Lingual Thyroid and absence of an orthotopic Thyroid gland. Summary: The aim of this study was to describe nonsurgical management of obstructive Lingual Thyroid tissue with 131I therapy for Lingual Thyroid radioablation. Patients were prepared with a low-iodine diet and levothyroxine withdr...