The Experts below are selected from a list of 106890 Experts worldwide ranked by ideXlab platform

Ana Varela - One of the best experts on this subject based on the ideXlab platform.

M U Eteng - One of the best experts on this subject based on the ideXlab platform.

  • vitamin c improves basal metabolic rate and Lipid Profile in alloxan induced diabetes mellitus in rats
    Journal of Biosciences, 2006
    Co-Authors: D U Owu, A B Antai, K H Udofia, A O Obembe, K O Obasi, M U Eteng
    Abstract:

    Diabetes mellitus (DM) is a multi-factorial disease which is characterized by hyperglycaemia, lipoprotein abnormalities and oxidative stress. This study evaluated effect of oral vitamin C administration on basal metabolic rate and Lipid Profile of alloxan-induced diabetic rats. Vitamin C was administered at 200 mg/kg body wt. by gavage for four weeks to diabetic rats after which the resting metabolic rate and plasma Lipid Profile was determined. The results showed that vitamin C administration significantly (P<0.01) reduced the resting metabolic rate in diabetic rats; and also lowered plasma triglyceride, total cholesterol and low-density lipoprotein cholesterol. These results suggest that the administration of vitamin C in this model of established diabetes mellitus might be beneficial for the restoration of basal metabolic rate and improvement of Lipid Profile. This may at least in part reduce the risk of cardiovascular events seen in diabetes mellitus.

Filipe Cunha - One of the best experts on this subject based on the ideXlab platform.

D U Owu - One of the best experts on this subject based on the ideXlab platform.

  • vitamin c improves basal metabolic rate and Lipid Profile in alloxan induced diabetes mellitus in rats
    Journal of Biosciences, 2006
    Co-Authors: D U Owu, A B Antai, K H Udofia, A O Obembe, K O Obasi, M U Eteng
    Abstract:

    Diabetes mellitus (DM) is a multi-factorial disease which is characterized by hyperglycaemia, lipoprotein abnormalities and oxidative stress. This study evaluated effect of oral vitamin C administration on basal metabolic rate and Lipid Profile of alloxan-induced diabetic rats. Vitamin C was administered at 200 mg/kg body wt. by gavage for four weeks to diabetic rats after which the resting metabolic rate and plasma Lipid Profile was determined. The results showed that vitamin C administration significantly (P<0.01) reduced the resting metabolic rate in diabetic rats; and also lowered plasma triglyceride, total cholesterol and low-density lipoprotein cholesterol. These results suggest that the administration of vitamin C in this model of established diabetes mellitus might be beneficial for the restoration of basal metabolic rate and improvement of Lipid Profile. This may at least in part reduce the risk of cardiovascular events seen in diabetes mellitus.

Masoud Khorshidi - One of the best experts on this subject based on the ideXlab platform.

  • effect of evening primrose oil supplementation on Lipid Profile a systematic review and meta analysis of randomized clinical trials
    Phytotherapy Research, 2020
    Co-Authors: Masoud Khorshidi, Meysam Zarezadeh, Omid Moradi Moghaddam, Mohammad Reza Emami, Hamed Kordvarkaneh, Seyed Mohammad Mousavi, Shahab Alizadeh, Javad Heshmati, Beheshteh Olang
    Abstract:

    Background Studies have shown that evening primrose oil (EPO) supplementation might be effective in improving Lipid Profile, however, the results are inconsistent. This study was performed to determine the direction and magnitude of the EPO effect on the Lipid Profile. Methods PubMed, Scopus, Cochrane Library, Embase and Web of Science databases and Google Scholar were searched up to September-2019. Meta-analysis was performed using the random-effects model. Lipid Profile including high-density lipoprotein (HDL), total cholesterol (TC), triglyceride (TG), and low-density lipoprotein (LDL) was considered as the primary outcome. Results A total of 926 articles were identified through database searching, of which, six RCTs were included in the meta-analysis. There were six studies on HDL, TC, and TG and four studies on LDL. EPO supplementation had no significant effect on TC, TG, LDL, and HDL. However, in subgroup analysis, a significant reduction in TG at a dose of ≤4 g/day (weighted mean difference [WMD] = -37.28 mg/dl; 95% CI: -73.53 to -1.03, p = .044) and a significant increase in HDL in hyperLipidemic subjects (WMD = 5.468 mg/dl; 95% CI: 1.323 to 9.614, p = .010) was found. Conclusion Oral intake of EPO at a dose of ≤4 g/day significantly reduces serum TG levels and significantly increases HDL levels in hyperLipidemic subjects.