The Experts below are selected from a list of 273 Experts worldwide ranked by ideXlab platform
Hans Gregersen - One of the best experts on this subject based on the ideXlab platform.
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stress strain analysis of duodenal contractility in response to fLow and ramp distension in rabbits fed Low Fiber Diet
Neurogastroenterology and Motility, 2019Co-Authors: Yue Liu, Jingbo Zhao, Donghua Liao, Guixue Wang, Hans GregersenAbstract:BACKGROUND Previously we demonstrated that Low-Fiber Diet in rabbits affects the passive mechanomorphological properties in the small intestine, resulting in reduced intestinal wall thickness and collagen content, as well as intestinal wall softening. The aim of the present study was to evaluate the contractility in rabbits on long-term Low-Fiber Diet and specifically to compare the contraction threshold, the frequency, and the amplitude of fLow-induced and distension-induced contractions in the duodenum between rabbits on normal Diet and on long-term Low-Fiber Diet. METHODS Ten rabbits were fed a Low-Fiber Diet for 5 months (Intervention group), and five rabbits were fed normal Diet (Control group). The duodenal segments were used for determination of mechanical parameters for analyses of contractility. The duodenal experiments were carried out in organ baths containing physiological Krebs solution. Pressure and diameter changes induced by contractions in response to fLow and ramp distension were measured. The frequencies and amplitude of contractions were analyzed. Distension-induced contraction thresholds and maximum contraction amplitude of fLow-induced contractions were calculated in terms of mechanical stress and strain. Multiple linear regression analyses were applied to study dependencies between contractility parameters and wall thickness, wall area, and muscle layer thickness. KEY RESULTS During distension, the pressure, stress, and strain thresholds for induction of phasic contraction were biggest in the Intervention Group (P < 0.05). In addition, the contraction frequencies during fLow-induced contraction were highest in the Intervention Group (P < 0.05), whereas the maximum contraction amplitudes in terms of pressure, diameter, stress, and strain were Lowest in the Intervention Group (P < 0.05). The contraction thresholds and contraction frequencies were negatively associated with the wall thickness, wall area, and muscle layer thickness, whereas maximum contraction amplitudes were positively associated with the wall thickness, wall area, and muscle layer thickness. CONCLUSIONS AND INFERENCES Duodenal contractility in rabbits fed with long-term Low-Fiber Diet exhibited Low contraction amplitudes and high contraction thresholds and frequencies. The changes were associated with the Low-Fiber Diet-induced histomorphological remodeling. Studies on detailed structural and functional Diet-induced changes in smooth muscle and intestinal nerves are needed for better understanding the remodeling mechanisms.
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Stress–strain analysis of duodenal contractility in response to fLow and ramp distension in rabbits fed Low‐Fiber Diet
Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society, 2018Co-Authors: Yue Liu, Jingbo Zhao, Donghua Liao, Guixue Wang, Hans GregersenAbstract:BACKGROUND Previously we demonstrated that Low-Fiber Diet in rabbits affects the passive mechanomorphological properties in the small intestine, resulting in reduced intestinal wall thickness and collagen content, as well as intestinal wall softening. The aim of the present study was to evaluate the contractility in rabbits on long-term Low-Fiber Diet and specifically to compare the contraction threshold, the frequency, and the amplitude of fLow-induced and distension-induced contractions in the duodenum between rabbits on normal Diet and on long-term Low-Fiber Diet. METHODS Ten rabbits were fed a Low-Fiber Diet for 5 months (Intervention group), and five rabbits were fed normal Diet (Control group). The duodenal segments were used for determination of mechanical parameters for analyses of contractility. The duodenal experiments were carried out in organ baths containing physiological Krebs solution. Pressure and diameter changes induced by contractions in response to fLow and ramp distension were measured. The frequencies and amplitude of contractions were analyzed. Distension-induced contraction thresholds and maximum contraction amplitude of fLow-induced contractions were calculated in terms of mechanical stress and strain. Multiple linear regression analyses were applied to study dependencies between contractility parameters and wall thickness, wall area, and muscle layer thickness. KEY RESULTS During distension, the pressure, stress, and strain thresholds for induction of phasic contraction were biggest in the Intervention Group (P
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Intestinal Mechanomorphological Remodeling Induced by Long-Term Low-Fiber Diet in Rabbits.
Annals of biomedical engineering, 2017Co-Authors: Yue Liu, Jingbo Zhao, Donghua Liao, Guixue Wang, Hans GregersenAbstract:Short-term feeding with Low-Fiber Diet remodels the mechanomorphological properties in the rabbit small intestine. The aims were to study the effect of feeding Low-Fiber Diet for 5 months on mechanomorphological properties including the collagen fraction in the rabbit intestines. Fifteen rabbits were divided into an Intervention group (IG, n = 10) fed a Low-Fiber Diet and a Control group (CG, n = 5) fed a normal Diet for 5 months. Five months later, four 10-cm-long segments obtained from the duodenum, jejunum, ileum and large intestine were used for histological and mechanical analysis, respectively. The wall thickness, wall area, mucosa and muscle layer thickness decreased whereas the submucosa layer thickness increased in the IG (p
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intestinal mechanomorphological remodeling induced by long term Low Fiber Diet in rabbits
Annals of Biomedical Engineering, 2017Co-Authors: Yue Liu, Jingbo Zhao, Donghua Liao, Guixue Wang, Hans GregersenAbstract:Short-term feeding with Low-Fiber Diet remodels the mechanomorphological properties in the rabbit small intestine. The aims were to study the effect of feeding Low-Fiber Diet for 5 months on mechanomorphological properties including the collagen fraction in the rabbit intestines. Fifteen rabbits were divided into an Intervention group (IG, n = 10) fed a Low-Fiber Diet and a Control group (CG, n = 5) fed a normal Diet for 5 months. Five months later, four 10-cm-long segments obtained from the duodenum, jejunum, ileum and large intestine were used for histological and mechanical analysis, respectively. The wall thickness, wall area, mucosa and muscle layer thickness decreased whereas the submucosa layer thickness increased in the IG (p < 0.05). The collagen fraction decreased in all layers and segments in the IG (p < 0.05). The opening angle increased in the large intestine and decreased in the ileum in the IG (p < 0.05). The intestinal stress-strain curves for IG shifted to the right, indicating softening. The creep did not change in the four segments. The wall stiffness was associated with wall thickness and collagen fraction in the submucosa layer. Long-term Low-Fiber Diet in rabbits induced histomorphometric and biomechanical remodelling of the intestines.
Yue Liu - One of the best experts on this subject based on the ideXlab platform.
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stress strain analysis of duodenal contractility in response to fLow and ramp distension in rabbits fed Low Fiber Diet
Neurogastroenterology and Motility, 2019Co-Authors: Yue Liu, Jingbo Zhao, Donghua Liao, Guixue Wang, Hans GregersenAbstract:BACKGROUND Previously we demonstrated that Low-Fiber Diet in rabbits affects the passive mechanomorphological properties in the small intestine, resulting in reduced intestinal wall thickness and collagen content, as well as intestinal wall softening. The aim of the present study was to evaluate the contractility in rabbits on long-term Low-Fiber Diet and specifically to compare the contraction threshold, the frequency, and the amplitude of fLow-induced and distension-induced contractions in the duodenum between rabbits on normal Diet and on long-term Low-Fiber Diet. METHODS Ten rabbits were fed a Low-Fiber Diet for 5 months (Intervention group), and five rabbits were fed normal Diet (Control group). The duodenal segments were used for determination of mechanical parameters for analyses of contractility. The duodenal experiments were carried out in organ baths containing physiological Krebs solution. Pressure and diameter changes induced by contractions in response to fLow and ramp distension were measured. The frequencies and amplitude of contractions were analyzed. Distension-induced contraction thresholds and maximum contraction amplitude of fLow-induced contractions were calculated in terms of mechanical stress and strain. Multiple linear regression analyses were applied to study dependencies between contractility parameters and wall thickness, wall area, and muscle layer thickness. KEY RESULTS During distension, the pressure, stress, and strain thresholds for induction of phasic contraction were biggest in the Intervention Group (P < 0.05). In addition, the contraction frequencies during fLow-induced contraction were highest in the Intervention Group (P < 0.05), whereas the maximum contraction amplitudes in terms of pressure, diameter, stress, and strain were Lowest in the Intervention Group (P < 0.05). The contraction thresholds and contraction frequencies were negatively associated with the wall thickness, wall area, and muscle layer thickness, whereas maximum contraction amplitudes were positively associated with the wall thickness, wall area, and muscle layer thickness. CONCLUSIONS AND INFERENCES Duodenal contractility in rabbits fed with long-term Low-Fiber Diet exhibited Low contraction amplitudes and high contraction thresholds and frequencies. The changes were associated with the Low-Fiber Diet-induced histomorphological remodeling. Studies on detailed structural and functional Diet-induced changes in smooth muscle and intestinal nerves are needed for better understanding the remodeling mechanisms.
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Stress–strain analysis of duodenal contractility in response to fLow and ramp distension in rabbits fed Low‐Fiber Diet
Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society, 2018Co-Authors: Yue Liu, Jingbo Zhao, Donghua Liao, Guixue Wang, Hans GregersenAbstract:BACKGROUND Previously we demonstrated that Low-Fiber Diet in rabbits affects the passive mechanomorphological properties in the small intestine, resulting in reduced intestinal wall thickness and collagen content, as well as intestinal wall softening. The aim of the present study was to evaluate the contractility in rabbits on long-term Low-Fiber Diet and specifically to compare the contraction threshold, the frequency, and the amplitude of fLow-induced and distension-induced contractions in the duodenum between rabbits on normal Diet and on long-term Low-Fiber Diet. METHODS Ten rabbits were fed a Low-Fiber Diet for 5 months (Intervention group), and five rabbits were fed normal Diet (Control group). The duodenal segments were used for determination of mechanical parameters for analyses of contractility. The duodenal experiments were carried out in organ baths containing physiological Krebs solution. Pressure and diameter changes induced by contractions in response to fLow and ramp distension were measured. The frequencies and amplitude of contractions were analyzed. Distension-induced contraction thresholds and maximum contraction amplitude of fLow-induced contractions were calculated in terms of mechanical stress and strain. Multiple linear regression analyses were applied to study dependencies between contractility parameters and wall thickness, wall area, and muscle layer thickness. KEY RESULTS During distension, the pressure, stress, and strain thresholds for induction of phasic contraction were biggest in the Intervention Group (P
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Intestinal Mechanomorphological Remodeling Induced by Long-Term Low-Fiber Diet in Rabbits.
Annals of biomedical engineering, 2017Co-Authors: Yue Liu, Jingbo Zhao, Donghua Liao, Guixue Wang, Hans GregersenAbstract:Short-term feeding with Low-Fiber Diet remodels the mechanomorphological properties in the rabbit small intestine. The aims were to study the effect of feeding Low-Fiber Diet for 5 months on mechanomorphological properties including the collagen fraction in the rabbit intestines. Fifteen rabbits were divided into an Intervention group (IG, n = 10) fed a Low-Fiber Diet and a Control group (CG, n = 5) fed a normal Diet for 5 months. Five months later, four 10-cm-long segments obtained from the duodenum, jejunum, ileum and large intestine were used for histological and mechanical analysis, respectively. The wall thickness, wall area, mucosa and muscle layer thickness decreased whereas the submucosa layer thickness increased in the IG (p
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intestinal mechanomorphological remodeling induced by long term Low Fiber Diet in rabbits
Annals of Biomedical Engineering, 2017Co-Authors: Yue Liu, Jingbo Zhao, Donghua Liao, Guixue Wang, Hans GregersenAbstract:Short-term feeding with Low-Fiber Diet remodels the mechanomorphological properties in the rabbit small intestine. The aims were to study the effect of feeding Low-Fiber Diet for 5 months on mechanomorphological properties including the collagen fraction in the rabbit intestines. Fifteen rabbits were divided into an Intervention group (IG, n = 10) fed a Low-Fiber Diet and a Control group (CG, n = 5) fed a normal Diet for 5 months. Five months later, four 10-cm-long segments obtained from the duodenum, jejunum, ileum and large intestine were used for histological and mechanical analysis, respectively. The wall thickness, wall area, mucosa and muscle layer thickness decreased whereas the submucosa layer thickness increased in the IG (p < 0.05). The collagen fraction decreased in all layers and segments in the IG (p < 0.05). The opening angle increased in the large intestine and decreased in the ileum in the IG (p < 0.05). The intestinal stress-strain curves for IG shifted to the right, indicating softening. The creep did not change in the four segments. The wall stiffness was associated with wall thickness and collagen fraction in the submucosa layer. Long-term Low-Fiber Diet in rabbits induced histomorphometric and biomechanical remodelling of the intestines.
Jingbo Zhao - One of the best experts on this subject based on the ideXlab platform.
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stress strain analysis of duodenal contractility in response to fLow and ramp distension in rabbits fed Low Fiber Diet
Neurogastroenterology and Motility, 2019Co-Authors: Yue Liu, Jingbo Zhao, Donghua Liao, Guixue Wang, Hans GregersenAbstract:BACKGROUND Previously we demonstrated that Low-Fiber Diet in rabbits affects the passive mechanomorphological properties in the small intestine, resulting in reduced intestinal wall thickness and collagen content, as well as intestinal wall softening. The aim of the present study was to evaluate the contractility in rabbits on long-term Low-Fiber Diet and specifically to compare the contraction threshold, the frequency, and the amplitude of fLow-induced and distension-induced contractions in the duodenum between rabbits on normal Diet and on long-term Low-Fiber Diet. METHODS Ten rabbits were fed a Low-Fiber Diet for 5 months (Intervention group), and five rabbits were fed normal Diet (Control group). The duodenal segments were used for determination of mechanical parameters for analyses of contractility. The duodenal experiments were carried out in organ baths containing physiological Krebs solution. Pressure and diameter changes induced by contractions in response to fLow and ramp distension were measured. The frequencies and amplitude of contractions were analyzed. Distension-induced contraction thresholds and maximum contraction amplitude of fLow-induced contractions were calculated in terms of mechanical stress and strain. Multiple linear regression analyses were applied to study dependencies between contractility parameters and wall thickness, wall area, and muscle layer thickness. KEY RESULTS During distension, the pressure, stress, and strain thresholds for induction of phasic contraction were biggest in the Intervention Group (P < 0.05). In addition, the contraction frequencies during fLow-induced contraction were highest in the Intervention Group (P < 0.05), whereas the maximum contraction amplitudes in terms of pressure, diameter, stress, and strain were Lowest in the Intervention Group (P < 0.05). The contraction thresholds and contraction frequencies were negatively associated with the wall thickness, wall area, and muscle layer thickness, whereas maximum contraction amplitudes were positively associated with the wall thickness, wall area, and muscle layer thickness. CONCLUSIONS AND INFERENCES Duodenal contractility in rabbits fed with long-term Low-Fiber Diet exhibited Low contraction amplitudes and high contraction thresholds and frequencies. The changes were associated with the Low-Fiber Diet-induced histomorphological remodeling. Studies on detailed structural and functional Diet-induced changes in smooth muscle and intestinal nerves are needed for better understanding the remodeling mechanisms.
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Stress–strain analysis of duodenal contractility in response to fLow and ramp distension in rabbits fed Low‐Fiber Diet
Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society, 2018Co-Authors: Yue Liu, Jingbo Zhao, Donghua Liao, Guixue Wang, Hans GregersenAbstract:BACKGROUND Previously we demonstrated that Low-Fiber Diet in rabbits affects the passive mechanomorphological properties in the small intestine, resulting in reduced intestinal wall thickness and collagen content, as well as intestinal wall softening. The aim of the present study was to evaluate the contractility in rabbits on long-term Low-Fiber Diet and specifically to compare the contraction threshold, the frequency, and the amplitude of fLow-induced and distension-induced contractions in the duodenum between rabbits on normal Diet and on long-term Low-Fiber Diet. METHODS Ten rabbits were fed a Low-Fiber Diet for 5 months (Intervention group), and five rabbits were fed normal Diet (Control group). The duodenal segments were used for determination of mechanical parameters for analyses of contractility. The duodenal experiments were carried out in organ baths containing physiological Krebs solution. Pressure and diameter changes induced by contractions in response to fLow and ramp distension were measured. The frequencies and amplitude of contractions were analyzed. Distension-induced contraction thresholds and maximum contraction amplitude of fLow-induced contractions were calculated in terms of mechanical stress and strain. Multiple linear regression analyses were applied to study dependencies between contractility parameters and wall thickness, wall area, and muscle layer thickness. KEY RESULTS During distension, the pressure, stress, and strain thresholds for induction of phasic contraction were biggest in the Intervention Group (P
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Intestinal Mechanomorphological Remodeling Induced by Long-Term Low-Fiber Diet in Rabbits.
Annals of biomedical engineering, 2017Co-Authors: Yue Liu, Jingbo Zhao, Donghua Liao, Guixue Wang, Hans GregersenAbstract:Short-term feeding with Low-Fiber Diet remodels the mechanomorphological properties in the rabbit small intestine. The aims were to study the effect of feeding Low-Fiber Diet for 5 months on mechanomorphological properties including the collagen fraction in the rabbit intestines. Fifteen rabbits were divided into an Intervention group (IG, n = 10) fed a Low-Fiber Diet and a Control group (CG, n = 5) fed a normal Diet for 5 months. Five months later, four 10-cm-long segments obtained from the duodenum, jejunum, ileum and large intestine were used for histological and mechanical analysis, respectively. The wall thickness, wall area, mucosa and muscle layer thickness decreased whereas the submucosa layer thickness increased in the IG (p
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intestinal mechanomorphological remodeling induced by long term Low Fiber Diet in rabbits
Annals of Biomedical Engineering, 2017Co-Authors: Yue Liu, Jingbo Zhao, Donghua Liao, Guixue Wang, Hans GregersenAbstract:Short-term feeding with Low-Fiber Diet remodels the mechanomorphological properties in the rabbit small intestine. The aims were to study the effect of feeding Low-Fiber Diet for 5 months on mechanomorphological properties including the collagen fraction in the rabbit intestines. Fifteen rabbits were divided into an Intervention group (IG, n = 10) fed a Low-Fiber Diet and a Control group (CG, n = 5) fed a normal Diet for 5 months. Five months later, four 10-cm-long segments obtained from the duodenum, jejunum, ileum and large intestine were used for histological and mechanical analysis, respectively. The wall thickness, wall area, mucosa and muscle layer thickness decreased whereas the submucosa layer thickness increased in the IG (p < 0.05). The collagen fraction decreased in all layers and segments in the IG (p < 0.05). The opening angle increased in the large intestine and decreased in the ileum in the IG (p < 0.05). The intestinal stress-strain curves for IG shifted to the right, indicating softening. The creep did not change in the four segments. The wall stiffness was associated with wall thickness and collagen fraction in the submucosa layer. Long-term Low-Fiber Diet in rabbits induced histomorphometric and biomechanical remodelling of the intestines.
Eva Lundin - One of the best experts on this subject based on the ideXlab platform.
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high Fiber rye Diet increases ileal excretion of energy and macronutrients compared with Low Fiber wheat Diet independent of meal frequency in ileostomy subjects
Food & Nutrition Research, 2013Co-Authors: Hanna Isaksson, Jie-xian Zhang, Eva Lundin, Goran Hallmans, Knud Erik Bach Knudsen, Rikard Landberg, Birgitta Sundberg, Per Tidehag, Ali A Moazzami, Per AmanAbstract:Background :Whole-grain foods and cereal Dietary Fiber intake is associated with Lower body weight. This may partly result from Lower energy utilization of high-Fiber Diets. Objective : In the present study, the impact on ileal excretion of energy and macronutrients in response to a rye bread high-Fiber Diet compared to a refined wheat Low-Fiber Diet was investigated. Furthermore, the effect of meal frequency on apparent absorption of nutrients was studied for the first time. Design : Ten participants that had undergone ileostomy consumed standardized iso-caloric Diets, including Low-Fiber wheat bread (20 g Dietary Fiber per day) for 2 weeks folLowed by high-Fiber rye bread (52 g Dietary Fiber per day) for 2 weeks. The Diets were consumed in an ordinary (three meals per day) and a nibbling (seven meals per day) meal frequency in a cross-over design. Ileal effluents were collected during 24 h at the third day of each of the four Dietary periods and analyzed for gross energy and nutrient contents. Results : The results showed that intake of rye bread high-Fiber Diet compared to the refined wheat Low-Fiber Diet caused an increase in ileal excretion of energy and macronutrients. The effect was independent of meal frequency. This suggests that a high intake of rye may result in Lower availability of macronutrients for small intestinal digestion and absorption. A regular intake of rye may therefore have implications for weight management. Keywords : rye bread; refined wheat; meal frequency; ileal excretion; ileostomy (Published: 12 December 2013) Citation: Food & Nutrition Research 2013. 57 : 18519 - http://dx.doi.org/10.3402/fnr.v57i0.18519
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intake of rye bread by ileostomists increases ileal excretion of Fiber polysaccharide components and organic acids but does not increase plasma or urine lignans and isoflavonoids
Journal of Nutrition, 1996Co-Authors: Dan Pettersson, Jie-xian Zhang, Eva Lundin, Per Aman, Goran Hallmans, Knud Erik Bach Knudsen, Helena Harkonen, Herman AdlercreutzAbstract:The excretion of starch, enzyme-resistant starch, Dietary Fiber components and organic acids (short-chain fatty acids plus lactic acid) as well as plasma and urine lignans and isoflavonoids was studied in eight ileostomists consuming mixed Diets with wheat bread (Low Fiber Diet) or rye bread (high Fiber Diet) in a crossover design. Average ileal excretions of enzyme-available starch were 3.5 g/d during the Low Fiber period and 4.1 g/d during the high Fiber period. The excretion of enzyme-resistant starch was approximately the same (2.3 g/d) in both periods. In comparison with intake, similar amounts of total Fiber residues were excreted both by subjects receiving the Low Fiber Diet (3.4 g/d) and by those receiving the high Fiber Diet (2.7 g/d). However, subjects excreted significantly more of certain polysaccharide residues (fucose, galactose, and uronic acids) than they ingested. On average, the excretion of organic acids was 18.6 mmol/d during the Low Fiber period and 30.2 mmol/d during the high Fiber period. No significant differences in plasma lignans were observed between the high Fiber and the Low Fiber Dietary periods. The present findings indicate that enzyme-available starch is highly digested and that a microbial breakdown of Dietary Fibers and probably other carbohydrates occurs in the small intestine. However, the bacterial activity in the ileostomists was not sufficient to cause an increased level in plasma lignans even when subjects consumed the high Fiber rye Diet.
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Excretion and degradation of Dietary Fiber constituents in ileostomy subjects consuming a Low Fiber Diet with and without brewer's spent grain.
Journal of Nutrition, 1994Co-Authors: Per Aman, Jie-xian Zhang, Goran Hallmans, Eva LundinAbstract:Excretion of total Dietary Fiber and Dietary Fiber components was studied in 10 human subjects with ileostomies, consuming in a crossover design a Low Fiber Diet (15 g total Dietary Fiber/d) or this Diet supplemented with 62 g/d of brewer's spent grain. Food and excreta were collected and analyzed on d 2, 3 and 7 of each Dietary period. No significant differences in excretion of total Dietary Fiber or Dietary Fiber components were found on the three days. Excreta from subjects consuming the Low Fiber Diet contained significantly more total Dietary Fiber than was ingested (20%, P
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Excretion and degradation of Dietary Fiber constituents in ileostomy subjects consuming a Low Fiber Diet with and without brewer's spent grain.
The Journal of nutrition, 1994Co-Authors: Per Aman, Jie-xian Zhang, Goran Hallmans, Eva LundinAbstract:Excretion of total Dietary Fiber and Dietary Fiber components was studied in 10 human subjects with ileostomies, consuming in a crossover design a Low Fiber Diet (15 g total Dietary Fiber/d) or this Diet supplemented with 62 g/d of brewer's spent grain. Food and excreta were collected and analyzed on d 2, 3 and 7 of each Dietary period. No significant differences in excretion of total Dietary Fiber or Dietary Fiber components were found on the three days. Excreta from subjects consuming the Low Fiber Diet contained significantly more total Dietary Fiber than was ingested (20%, P < 0.01), indicating the importance of endogenous and microbial material, contributing to the total Dietary Fiber value, in ileostomy effluents. Analysis of specific Dietary Fiber components showed that this increased excretion was mainly due to fucose, mannose, galactose and uronic acid residues. When the high-Fiber Diet was consumed, there was a significantly greater excretion of the same non-starch polysaccharide residues as for consumption of the Low Fiber Diet, but with a simultaneous decrease in excretion of arabinose, xylose and glucose residues (12%, P < 0.01), which were the major Fiber components in the Diet.
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effect of oat bran on plasma cholesterol and bile acid excretion in nine subjects with ileostomies
The American Journal of Clinical Nutrition, 1992Co-Authors: Jie-xian Zhang, Eva Lundin, H Andersson, Ingvar Bosaeus, Per Aman, Goran Hallmans, P Tidehag, Roger Stenling, S DahlgrenAbstract:A higher excretion of dry matter, fat, nitrogen, energy, and total bile acids in ileal effluents; a Lower plasma Low-density-lipoprotein (LDL) and total cholesterols (12.1% and 9.0% Lower respectively); but no change in plasma high-density-lipoprotein (HDL) cholesterol or apolipoproteins A-I and B were observed in nine subjects with ileostomies when they consumed an oat-bran, bread-based, high-Fiber Diet (HFD) as compared with a wheat-flour, bread-based, Low-Fiber Diet (LFD) for 3 wk with a crossover design. Of the nine subjects only the subjects with a Low daily excretion of bile acids had an elevated excretion of total bile acids during the HFD compared with the LFD. Total cholesterol, LDL cholesterol, and apolipoprotein B in plasma also decreased by 11.3%, 15.3%, and 10.7%, respectively, after consumption of the HFD for 3 wk.
Per Aman - One of the best experts on this subject based on the ideXlab platform.
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high Fiber rye Diet increases ileal excretion of energy and macronutrients compared with Low Fiber wheat Diet independent of meal frequency in ileostomy subjects
Food & Nutrition Research, 2013Co-Authors: Hanna Isaksson, Jie-xian Zhang, Eva Lundin, Goran Hallmans, Knud Erik Bach Knudsen, Rikard Landberg, Birgitta Sundberg, Per Tidehag, Ali A Moazzami, Per AmanAbstract:Background :Whole-grain foods and cereal Dietary Fiber intake is associated with Lower body weight. This may partly result from Lower energy utilization of high-Fiber Diets. Objective : In the present study, the impact on ileal excretion of energy and macronutrients in response to a rye bread high-Fiber Diet compared to a refined wheat Low-Fiber Diet was investigated. Furthermore, the effect of meal frequency on apparent absorption of nutrients was studied for the first time. Design : Ten participants that had undergone ileostomy consumed standardized iso-caloric Diets, including Low-Fiber wheat bread (20 g Dietary Fiber per day) for 2 weeks folLowed by high-Fiber rye bread (52 g Dietary Fiber per day) for 2 weeks. The Diets were consumed in an ordinary (three meals per day) and a nibbling (seven meals per day) meal frequency in a cross-over design. Ileal effluents were collected during 24 h at the third day of each of the four Dietary periods and analyzed for gross energy and nutrient contents. Results : The results showed that intake of rye bread high-Fiber Diet compared to the refined wheat Low-Fiber Diet caused an increase in ileal excretion of energy and macronutrients. The effect was independent of meal frequency. This suggests that a high intake of rye may result in Lower availability of macronutrients for small intestinal digestion and absorption. A regular intake of rye may therefore have implications for weight management. Keywords : rye bread; refined wheat; meal frequency; ileal excretion; ileostomy (Published: 12 December 2013) Citation: Food & Nutrition Research 2013. 57 : 18519 - http://dx.doi.org/10.3402/fnr.v57i0.18519
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intake of rye bread by ileostomists increases ileal excretion of Fiber polysaccharide components and organic acids but does not increase plasma or urine lignans and isoflavonoids
Journal of Nutrition, 1996Co-Authors: Dan Pettersson, Jie-xian Zhang, Eva Lundin, Per Aman, Goran Hallmans, Knud Erik Bach Knudsen, Helena Harkonen, Herman AdlercreutzAbstract:The excretion of starch, enzyme-resistant starch, Dietary Fiber components and organic acids (short-chain fatty acids plus lactic acid) as well as plasma and urine lignans and isoflavonoids was studied in eight ileostomists consuming mixed Diets with wheat bread (Low Fiber Diet) or rye bread (high Fiber Diet) in a crossover design. Average ileal excretions of enzyme-available starch were 3.5 g/d during the Low Fiber period and 4.1 g/d during the high Fiber period. The excretion of enzyme-resistant starch was approximately the same (2.3 g/d) in both periods. In comparison with intake, similar amounts of total Fiber residues were excreted both by subjects receiving the Low Fiber Diet (3.4 g/d) and by those receiving the high Fiber Diet (2.7 g/d). However, subjects excreted significantly more of certain polysaccharide residues (fucose, galactose, and uronic acids) than they ingested. On average, the excretion of organic acids was 18.6 mmol/d during the Low Fiber period and 30.2 mmol/d during the high Fiber period. No significant differences in plasma lignans were observed between the high Fiber and the Low Fiber Dietary periods. The present findings indicate that enzyme-available starch is highly digested and that a microbial breakdown of Dietary Fibers and probably other carbohydrates occurs in the small intestine. However, the bacterial activity in the ileostomists was not sufficient to cause an increased level in plasma lignans even when subjects consumed the high Fiber rye Diet.
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Excretion and degradation of Dietary Fiber constituents in ileostomy subjects consuming a Low Fiber Diet with and without brewer's spent grain.
Journal of Nutrition, 1994Co-Authors: Per Aman, Jie-xian Zhang, Goran Hallmans, Eva LundinAbstract:Excretion of total Dietary Fiber and Dietary Fiber components was studied in 10 human subjects with ileostomies, consuming in a crossover design a Low Fiber Diet (15 g total Dietary Fiber/d) or this Diet supplemented with 62 g/d of brewer's spent grain. Food and excreta were collected and analyzed on d 2, 3 and 7 of each Dietary period. No significant differences in excretion of total Dietary Fiber or Dietary Fiber components were found on the three days. Excreta from subjects consuming the Low Fiber Diet contained significantly more total Dietary Fiber than was ingested (20%, P
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Excretion and degradation of Dietary Fiber constituents in ileostomy subjects consuming a Low Fiber Diet with and without brewer's spent grain.
The Journal of nutrition, 1994Co-Authors: Per Aman, Jie-xian Zhang, Goran Hallmans, Eva LundinAbstract:Excretion of total Dietary Fiber and Dietary Fiber components was studied in 10 human subjects with ileostomies, consuming in a crossover design a Low Fiber Diet (15 g total Dietary Fiber/d) or this Diet supplemented with 62 g/d of brewer's spent grain. Food and excreta were collected and analyzed on d 2, 3 and 7 of each Dietary period. No significant differences in excretion of total Dietary Fiber or Dietary Fiber components were found on the three days. Excreta from subjects consuming the Low Fiber Diet contained significantly more total Dietary Fiber than was ingested (20%, P < 0.01), indicating the importance of endogenous and microbial material, contributing to the total Dietary Fiber value, in ileostomy effluents. Analysis of specific Dietary Fiber components showed that this increased excretion was mainly due to fucose, mannose, galactose and uronic acid residues. When the high-Fiber Diet was consumed, there was a significantly greater excretion of the same non-starch polysaccharide residues as for consumption of the Low Fiber Diet, but with a simultaneous decrease in excretion of arabinose, xylose and glucose residues (12%, P < 0.01), which were the major Fiber components in the Diet.
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effect of oat bran on plasma cholesterol and bile acid excretion in nine subjects with ileostomies
The American Journal of Clinical Nutrition, 1992Co-Authors: Jie-xian Zhang, Eva Lundin, H Andersson, Ingvar Bosaeus, Per Aman, Goran Hallmans, P Tidehag, Roger Stenling, S DahlgrenAbstract:A higher excretion of dry matter, fat, nitrogen, energy, and total bile acids in ileal effluents; a Lower plasma Low-density-lipoprotein (LDL) and total cholesterols (12.1% and 9.0% Lower respectively); but no change in plasma high-density-lipoprotein (HDL) cholesterol or apolipoproteins A-I and B were observed in nine subjects with ileostomies when they consumed an oat-bran, bread-based, high-Fiber Diet (HFD) as compared with a wheat-flour, bread-based, Low-Fiber Diet (LFD) for 3 wk with a crossover design. Of the nine subjects only the subjects with a Low daily excretion of bile acids had an elevated excretion of total bile acids during the HFD compared with the LFD. Total cholesterol, LDL cholesterol, and apolipoprotein B in plasma also decreased by 11.3%, 15.3%, and 10.7%, respectively, after consumption of the HFD for 3 wk.
