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Dinnen P. - One of the best experts on this subject based on the ideXlab platform.
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Triage of patients with venous and Lymphatic Diseases during the COVID-19 pandemic – The Venous and Lymphatic Triage and Acuity Scale (VELTAS):: A consensus document of the International Union of Phlebology (UIP), Australasian College of Phlebology (ACP), American Vein and Lymphatic Society (AVLS), American Venous Forum (AVF), European College of Phlebology (ECoP), European Venous Forum (EVF), Interventional Radiology Society of Australasia (IRSA), Latin American Venous Forum, Pan-American Society of Phlebology and Lymphology and the Venous Association of India (VAI)
'Elsevier BV', 2020Co-Authors: Parsi K., Rij, A.m. Van, Meissner, M.h. H.), Davies A.h., M.g.r. De ,maeseneer, Gloviczki P., Benson S., Bottini O., Manuel Canata, Dinnen P.Abstract:The coronavirus Disease 2019 (COVID-19) global pandemic has resulted in diversion of healthcare resources to the management of patients infected with SARS-CoV-2 virus. Elective interventions and surgical procedures in most countries have been postponed and operating room resources have been diverted to manage the pandemic. The Venous and Lymphatic Triage and Acuity Scale was developed to provide an international standard to rationalise and harmonise the management of patients with venous and Lymphatic disorders or vascular anomalies. Triage urgency was determined based on clinical assessment of urgency with which a patient would require medical treatment or surgical intervention. Clinical conditions were classified into six categories of: (1) venous thromboembolism (VTE), (2) chronic venous Disease, (3) vascular anomalies, (4) venous trauma, (5) venous compression and (6) Lymphatic Disease. Triage urgency was categorised into four groups and individual conditions were allocated to each class of triage. These included (1) medical emergencies (requiring immediate attendance), example massive pulmonary embolism; (2) urgent (to be seen as soon as possible), example deep vein thrombosis; (3) semiurgent (to be attended to within 30-90 days), example highly symptomatic chronic venous Disease, and (4) discretionary/nonurgent- (to be seen within 6-12 months), example chronic lymphoedema. Venous and Lymphatic Triage and Acuity Scale aims to standardise the triage of patients with venous and Lymphatic Disease or vascular anomalies by providing an international consensus-based classification of clinical categories and triage urgency. The scale may be used during pandemics such as the current COVID-19 crisis but may also be used as a general framework to classify urgency of the listed conditions
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Triage of patients with venous and Lymphatic Diseases during the COVID-19 pandemic – The Venous and Lymphatic Triage and Acuity Scale (VELTAS): A consensus document of the International Union of Phlebology (UIP), Australasian College of Phlebology (ACP), American Vein and Lymphatic Society (AVLS), American Venous Forum (AVF), European College of Phlebology (ECoP), European Venous Forum (EVF), Interventional Radiology Society of Australasia (IRSA), Latin American Venous Forum, Pan-American Society of Phlebology and Lymphology and the Venous Association of India (VAI)
'SAGE Publications', 2020Co-Authors: Parsi K., Rij, A.m. Van, Meissner, M.h. H.), Davies A.h., M.g.r. De ,maeseneer, Gloviczki P., Benson S., Bottini O., Canata, V.m. Manuel), Dinnen P.Abstract:The coronavirus Disease 2019 (COVID-19) global pandemic has resulted in diversion of healthcare resources to the management of patients infected with SARS-CoV-2 virus. Elective interventions and surgical procedures in most countries have been postponed and operating room resources have been diverted to manage the pandemic. The Venous and Lymphatic Triage and Acuity Scale was developed to provide an international standard to rationalise and harmonise the management of patients with venous and Lymphatic disorders or vascular anomalies. Triage urgency was determined based on clinical assessment of urgency with which a patient would require medical treatment or surgical intervention. Clinical conditions were classified into six categories of: (1) venous thromboembolism (VTE), (2) chronic venous Disease, (3) vascular anomalies, (4) venous trauma, (5) venous compression and (6) Lymphatic Disease. Triage urgency was categorised into four groups and individual conditions were allocated to each class of triage. These included (1) medical emergencies (requiring immediate attendance), example massive pulmonary embolism; (2) urgent (to be seen as soon as possible), example deep vein thrombosis; (3) semi-urgent (to be attended to within 30–90 days), example highly symptomatic chronic venous Disease, and (4) discretionary/non-urgent- (to be seen within 6–12 months), example chronic lymphoedema. Ven
Caroline Cheng - One of the best experts on this subject based on the ideXlab platform.
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Lymphatic vascular regeneration the next step in tissue engineering
Tissue Engineering Part B-reviews, 2015Co-Authors: Eline Huethorst, Merle M Krebber, Joost O Fledderus, Hendrik Gremmels, Jiayi Pei, Marianne C Verhaar, Caroline ChengAbstract:The Lymphatic system plays a crucial role in interstitial fluid drainage, lipid absorption, and immunological defense. Lymphatic dysfunction results in lymphedema, fluid accumulation, and swelling of soft tissues, as well as a potentially impaired immune response. Lymphedema significantly reduces quality of life of patients on a physical, mental, social, and economic basis. Current therapeutic approaches in treatment of Lymphatic Disease are limited. Over the last decades, great progress has been made in the development of therapeutic strategies to enhance vascular regeneration. These solutions to treat vascular Disease may also be applicable in the treatment of Lymphatic Diseases. Comparison of the organogenic process and biological organization of the vascular and Lymphatic systems and studies in the regulatory mechanisms involved in lymphangiogenesis and angiogenesis show many common features. In this study, we address the similarities between both transport systems, and focus in depth on the biology of Lymphatic development. Based on the current advances in vascular regeneration, we propose different strategies for Lymphatic tissue engineering that may be used for treatment of primary and secondary lymphedema.
Stanley G Rockson - One of the best experts on this subject based on the ideXlab platform.
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establishing standards for centers of excellence for the diagnosis and treatment of Lymphatic Disease
Lymphatic Research and Biology, 2021Co-Authors: David W Chang, Stanley G Rockson, Joseph Dayan, Phyllis Fried, Ketan M Patel, William Repicci, Dhruv Singhal, Melissa B AldrichAbstract:Background: Lymphatic Disease patients make up a significant proportion of the US and world populations. Due to inadequate medical school training and underestimation of the impact of Lymphatic circulation, Lymphatic Disease patients often have difficulty finding competent diagnosis and care. Methods and Results: The Lymphatic Education & Research Network has initiated a Centers of Excellence program to designate institutions that provide services for Lymphatic Disease patients. Committees of experts drafted standards for five types of Centers of Excellence. Conclusions: The Centers of Excellence program is now launched, and the description of the formation process herein could provide other organizations guidance for similar ventures.
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comorbidity and Lymphatic Disease the Lymphatic continuum re examined
Lymphatic Research and Biology, 2021Co-Authors: Stanley G RocksonAbstract:It has now been ∼20 years since the original Lymphatic Continuum conference was convened, and this continuum has transitioned from a compelling concept to a reality. The explosive growth in our com...
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new developments in clinical aspects of Lymphatic Disease
Journal of Clinical Investigation, 2014Co-Authors: P S Mortimer, Stanley G RocksonAbstract:The Lymphatic system is fundamentally important to cardiovascular Disease, infection and immunity, cancer, and probably obesity--the four major challenges in healthcare in the 21st century. This Review will consider the manner in which new knowledge of Lymphatic genes and molecular mechanisms has demonstrated that Lymphatic dysfunction should no longer be considered a passive bystander in Disease but rather an active player in many pathological processes and, therefore, a genuine target for future therapeutic developments. The specific roles of the Lymphatic system in edema, genetic aspects of primary lymphedema, infection (cellulitis/erysipelas), Crohn's Disease, obesity, cancer, and cancer-related lymphedema are highlighted.
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causes and consequences of Lymphatic Disease
Annals of the New York Academy of Sciences, 2010Co-Authors: Stanley G RocksonAbstract:The visceral manifestations of Lymphatic disorders (lymphangiomatosis and lymphangiectasia) are particularly severe. Any pathology of the Lymphatic vasculature, whether superficial or internal, regional, or systemic, is predominated by the appearance of lymphedema, the characteristic form of tissue edema that occurs when Lymphatic dysfunction supervenes. Disease manifestations may include dysregulation of body fluid homeostasis, immune traffic impairment, and disturbances of lipid and protein reabsorption from the gut lumen. The appearance of Lymphatic edema invokes complex biological alterations. Many of these changes seem to relate uniquely to chronic Lymphatic edema, including a profound stimulus to collagen and adipose deposition. Despite the recent advances in our understanding of these disorders, substantial knowledge gaps remain; these gaps inhibit our ability to accurately identify, categorize, treat, and prevent these Diseases. Future diagnostic, therapeutic, and reproductive decisions for affected individuals require an accurate knowledge of the clinical and laboratory presentation, mode of inheritance, treatment response, outcomes, and prognosis.
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the clinical spectrum of Lymphatic Disease
Annals of the New York Academy of Sciences, 2008Co-Authors: Kavita Radhakrishnan, Stanley G RocksonAbstract:Lymphatic Disease is quite prevalent, and often not well clinically characterized. Beyond lymphedema, there is a broad array of human Disease that directly or indirectly alters Lymphatic structure and function. The symptomatic and objective presentation of these patients can be quite diverse. In this review, we have attempted to provide a systematic overview of the subjective and objective spectrum of Lymphatic Disease, with consideration of all of the categories of Disease that primarily or secondarily impair the functional integrity of the Lymphatic system. Lymphedema is discussed, along with chromosomal disorders, lymphangioma, infectious Diseases, lymphangioleiomyomatosis, lipedema, heritable genetic disorders, complex vascular malformations, protein-losing enteropathy, and intestinal lymphangiectasia.
Kevin L Winthrop - One of the best experts on this subject based on the ideXlab platform.
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the clinical management and outcome of nail salon acquired mycobacterium fortuitum skin infection
Clinical Infectious Diseases, 2004Co-Authors: Kevin L Winthrop, Kim Albridge, David South, Peggy Albrecht, Marcy Abrams, Michael C Samuel, Wendy Leonard, Joanna Wagner, Duc J VugiaAbstract:Nontuberculous mycobacterial infections are becoming more common. Recently, Mycobacterium fortuitum and other rapidly growing mycobacteria have been found to cause severe skin and soft-tissue infections in association with nail salon whirlpool footbaths. We recently investigated a large outbreak of M. fortuitum furunculosis among women who received pedicures at a single nail salon. To better define the clinical course of such infections, we collected clinical details from physicians who were treating outbreak patients. We constructed multivariable linear models to evaluate the effect of antibiotic treatment on Disease duration. Sixty-one patients were included in the investigation. The mean Disease duration was 170 days (range, 41-336 days). Forty-eight persons received antibiotic therapy for a median period of 4 months (range, 1-6 months), and 13 persons were untreated. Isolates were most susceptible to ciprofloxacin and minocycline. Early administration of therapy was associated with shorter duration of Disease only in persons with multiple boils (P<.01). One untreated, healthy patient had Lymphatic Disease dissemination.
Parsi K. - One of the best experts on this subject based on the ideXlab platform.
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Triage of patients with venous and Lymphatic Diseases during the COVID-19 pandemic – The Venous and Lymphatic Triage and Acuity Scale (VELTAS):: A consensus document of the International Union of Phlebology (UIP), Australasian College of Phlebology (ACP), American Vein and Lymphatic Society (AVLS), American Venous Forum (AVF), European College of Phlebology (ECoP), European Venous Forum (EVF), Interventional Radiology Society of Australasia (IRSA), Latin American Venous Forum, Pan-American Society of Phlebology and Lymphology and the Venous Association of India (VAI)
'Elsevier BV', 2020Co-Authors: Parsi K., Rij, A.m. Van, Meissner, M.h. H.), Davies A.h., M.g.r. De ,maeseneer, Gloviczki P., Benson S., Bottini O., Manuel Canata, Dinnen P.Abstract:The coronavirus Disease 2019 (COVID-19) global pandemic has resulted in diversion of healthcare resources to the management of patients infected with SARS-CoV-2 virus. Elective interventions and surgical procedures in most countries have been postponed and operating room resources have been diverted to manage the pandemic. The Venous and Lymphatic Triage and Acuity Scale was developed to provide an international standard to rationalise and harmonise the management of patients with venous and Lymphatic disorders or vascular anomalies. Triage urgency was determined based on clinical assessment of urgency with which a patient would require medical treatment or surgical intervention. Clinical conditions were classified into six categories of: (1) venous thromboembolism (VTE), (2) chronic venous Disease, (3) vascular anomalies, (4) venous trauma, (5) venous compression and (6) Lymphatic Disease. Triage urgency was categorised into four groups and individual conditions were allocated to each class of triage. These included (1) medical emergencies (requiring immediate attendance), example massive pulmonary embolism; (2) urgent (to be seen as soon as possible), example deep vein thrombosis; (3) semiurgent (to be attended to within 30-90 days), example highly symptomatic chronic venous Disease, and (4) discretionary/nonurgent- (to be seen within 6-12 months), example chronic lymphoedema. Venous and Lymphatic Triage and Acuity Scale aims to standardise the triage of patients with venous and Lymphatic Disease or vascular anomalies by providing an international consensus-based classification of clinical categories and triage urgency. The scale may be used during pandemics such as the current COVID-19 crisis but may also be used as a general framework to classify urgency of the listed conditions
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Triage of patients with venous and Lymphatic Diseases during the COVID-19 pandemic – The Venous and Lymphatic Triage and Acuity Scale (VELTAS): A consensus document of the International Union of Phlebology (UIP), Australasian College of Phlebology (ACP), American Vein and Lymphatic Society (AVLS), American Venous Forum (AVF), European College of Phlebology (ECoP), European Venous Forum (EVF), Interventional Radiology Society of Australasia (IRSA), Latin American Venous Forum, Pan-American Society of Phlebology and Lymphology and the Venous Association of India (VAI)
'SAGE Publications', 2020Co-Authors: Parsi K., Rij, A.m. Van, Meissner, M.h. H.), Davies A.h., M.g.r. De ,maeseneer, Gloviczki P., Benson S., Bottini O., Canata, V.m. Manuel), Dinnen P.Abstract:The coronavirus Disease 2019 (COVID-19) global pandemic has resulted in diversion of healthcare resources to the management of patients infected with SARS-CoV-2 virus. Elective interventions and surgical procedures in most countries have been postponed and operating room resources have been diverted to manage the pandemic. The Venous and Lymphatic Triage and Acuity Scale was developed to provide an international standard to rationalise and harmonise the management of patients with venous and Lymphatic disorders or vascular anomalies. Triage urgency was determined based on clinical assessment of urgency with which a patient would require medical treatment or surgical intervention. Clinical conditions were classified into six categories of: (1) venous thromboembolism (VTE), (2) chronic venous Disease, (3) vascular anomalies, (4) venous trauma, (5) venous compression and (6) Lymphatic Disease. Triage urgency was categorised into four groups and individual conditions were allocated to each class of triage. These included (1) medical emergencies (requiring immediate attendance), example massive pulmonary embolism; (2) urgent (to be seen as soon as possible), example deep vein thrombosis; (3) semi-urgent (to be attended to within 30–90 days), example highly symptomatic chronic venous Disease, and (4) discretionary/non-urgent- (to be seen within 6–12 months), example chronic lymphoedema. Ven