The Experts below are selected from a list of 2793 Experts worldwide ranked by ideXlab platform

Kenshi Yao - One of the best experts on this subject based on the ideXlab platform.

Akinori Iwashita - One of the best experts on this subject based on the ideXlab platform.

Mototsugu Kato - One of the best experts on this subject based on the ideXlab platform.

  • Magnifying Endoscopy with narrow band imaging for predicting the invasion depth of superficial esophageal squamous cell carcinoma
    Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus, 2009
    Co-Authors: Kenichi Goda, Mototsugu Kato, Noboru Yoshimura, Kazuki Sumiyama, Masahiro Ikegami, Hisao Tajiri, Yukinaga Yoshida, Hiroo Imazu, Koji Matsuda, Mituru Kaise
    Abstract:

    SUMMARY The invasion depth of superficial esophageal squamous cell carcinoma is important in determining therapeutic strategy. The aim of this study was to prospectively investigate the clinical utility of Magnifying Endoscopy with narrow band imaging compared with that of non-Magnifying high-resolution Endoscopy or high-frequency endoscopic ultrasonography in predicting the depth of superficial esophageal squamous cell carcinoma. The techniques were carried out in 72 patients with 101 superficial esophageal squamous cell carcinomas, which were then resected by either endoscopic mucosal resection or esophagectomy. The histological invasion depth was divided into two: mucosal or submucosal carcinoma. We investigated the relationship between endoscopic staging and histology of tumor depth. Non-Magnifying high-resolution Endoscopy, Magnifying Endoscopy with narrow band imaging, and high-frequency endoscopic ultrasonography had overestimation/underestimation rates of 7/5, 4/4 and 8/3%, respectively. The sensitivity rates for the three techniques were 72, 78, and 83%, respectively, and the specificity rates were 92, 95, and 89%, respectively. There were no statistically significant differences among the three endoscopic techniques. Clinical utility of Magnifying Endoscopy with narrow band imaging does not seem to be significantly different from that of non-Magnifying high-resolution Endoscopy or high-frequency endoscopic ultrasonography in predicting the depth of superficial esophageal squamous cell carcinoma. Magnifying Endoscopy with narrow band imaging may have potential to reduce overestimation risks of non-Magnifying high-resolution Endoscopy or high-frequency endoscopic ultrasonography.

  • USEFULNESS OF Magnifying Endoscopy IN UPPER GASTROINTESTINAL TRACT: HISTORY AND RECENT STUDIES
    Digestive Endoscopy, 2005
    Co-Authors: Mototsugu Kato, Souichi Nakagawa, Yuichi Shimizu, Junji Yamamoto, Masahiro Asaka
    Abstract:

    Summary Although clinical trials using Magnifying optical Endoscopy have been reported, Magnifying endoscopies have been remarkably developed in the period of electronic Endoscopy. Magnifying electronic endoscopies with 80 or 100-fold magnification are used for routine endoscopic examination of upper gastrointestinal tract in Japan. Magnifying Endoscopy is used to visualize the microstructure and microvascular architecture of gastrointestinal surface mucosa. Microsurface structure of the mucosa includes normal structure, changed structure by inflammation and biological response, and tumor-specific structure. Microvascular architecture includes normal vascular system and tumor microvessels. Magnifying Endoscopy is starting to play an important role in diagnosis of any upper gastrointestinal diseases by assessment of magnified observation. Magnifying Endoscopy holds a great deal of promise in the near future because Magnifying endoscopic observation is approaching optical biopsy.

  • Relationship between histopathologic gastritis and mucosal microvascularity: observations with Magnifying Endoscopy.
    Gastrointestinal endoscopy, 2003
    Co-Authors: Souichi Nakagawa, Mototsugu Kato, Yuichi Shimizu, Manabu Nakagawa, Junji Yamamoto, Perez Aldana Luis, Junichi Kodaira, Mitsuru Kawarasaki, Hiroshi Takeda, Toshiro Sugiyama
    Abstract:

    Abstract Background: The purpose of this study was to determine the usefulness of Magnifying Endoscopy for the diagnosis of Helicobacter pylori -induced histopathologic gastritis. Methods: A total of 92 patients scheduled to undergo routine endoscopic examination were enrolled. After routine endoscopic examination, 3 sites in the stomach were studied by magnified observation. Visualized collecting venulae were classified into the following 3 patterns: regular, irregular, and obscured. The sites observed by Magnifying Endoscopy were assessed histopathologically with an Updated Sydney System; 4 morphologic parameters (activity, inflammation, atrophy, metaplasia) were assessed and graded from 0 to 3. Results: The regular pattern cases were negative for H pylori infection at all sites observed by Magnifying Endoscopy (antrum greater curve, 0/11; body greater curve, 0/24; body lesser curve, 0/23). The scores for all 4 morphologic parameters were significantly lower in the regular pattern group than the irregular and obscured groups ( p p Conclusion: Visibility of collecting venulae in the gastric mucosa is influenced by H pylori -induced histopathologic gastritis. Magnifying Endoscopy is useful for the diagnosis of histopathologic gastritis. (Gastrointest Endosc 2003;58:71-5.)

Takashi Hisabe - One of the best experts on this subject based on the ideXlab platform.

Hisao Tajiri - One of the best experts on this subject based on the ideXlab platform.