The Experts below are selected from a list of 21 Experts worldwide ranked by ideXlab platform

Oh Sook Kwon - One of the best experts on this subject based on the ideXlab platform.

  • Mesotherapy for Treatment of Male-Type Alopecia
    Simplified Facial Rejuvenation, 1
    Co-Authors: Oh Sook Kwon
    Abstract:

    Male-Type Alopecia is called androgenic Alopecia or bald hair and this Type usually begins to show in the late 20s or 30s. The patients have thin and soft hair from the frontal to the vertex area of the head instead of thick and healthy hair. This happens from the effects of Male hormones and only thin, soft and short hair shows because of the short period of the anagen stage (Fig. 55.1). Male-Type Alopecia usually starts with an M shape that starts from the frontal area of the head or starts from the vertex of the head. But the posterior hair and temporal hair remain because of the effects of Male hormones.

W. C. Song - One of the best experts on this subject based on the ideXlab platform.

  • Morphological and morphometric study of the androgenetic alopecic scalp using two‐ and three‐dimensional analysis comparing regional differences
    The British journal of dermatology, 2014
    Co-Authors: J.n. Kim, J.y. Lee, K.j. Shin, Young-chun Gil, Ki-seok Koh, W. C. Song
    Abstract:

    Summary Background Androgenetic (Male-Type) Alopecia (AGA) is caused by genetic and androgenetic effects. The progression of baldness results in smaller hair papillae, thinner hair and a shortened hair cycle. Alopecia occurs mainly in the frontal region and, to a lesser extent, in the occipital region. Objectives The morphological differences in the hair follicular units between the alopecic frontal scalp and the vertex and occipital regions were compared using cross-sectional histology and three-dimensional reconstruction. Methods Skin specimens were obtained from the frontal, vertex and occipital regions of 24 Male human cadavers with fully progressed AGA, and from the frontal region of 32 normal cadaveric scalps. These specimens were fixed, processed using routine histological methods, serially sectioned at a thickness of 10 μm and then stained with Masson's trichrome. The serial sections were reconstructed three-dimensionally using ‘Reconstruct’ software. Results The ratios between the numbers of terminal and vellus hairs in the frontal and occipital regions in the AGA scalps were 0·2 : 1 and 3·5 : 1, respectively. Almost all of the hair follicles in the frontal region were vellus hair follicles. The sebaceous gland and arrector pili muscle were larger in the frontal region than in the occipital region. Conclusions The morphology of the AGA scalp has been characterized. The terminal-to-vellus hair ratio in the occipital (normal) region was different from that in the frontal (alopecic) region. Moreover, sebaceous glands were larger in the frontal alopecic region than in the occipital region. These larger glands may be associated with other dermatological pathologies, such as seborrhoeic dermatitis.

Ryuichiro Kuwana - One of the best experts on this subject based on the ideXlab platform.

  • experience of fj30 lotion for Male Type Alopecia
    Nishi Nihon Hifuka, 1996
    Co-Authors: Ryuichiro Kuwana
    Abstract:

    男性型脱毛症に対してFJ30ローション(桑白皮エキスと柿葉エキスを混合したもの)およびフロジン®液を使用し, その臨床効果, 安全性および有用性を比較検討した。総症例数は111例であった。その結果, 本ローション外用群の方がフロジン®液外用群よりも優れた育毛効果を示し多くの症例で軟毛あるいは硬毛の新生がみられた。両群とも副作用は特に認められなかった。以上よりFJ30ローションは男性型脱毛に有用な外用剤と思われた。

J.n. Kim - One of the best experts on this subject based on the ideXlab platform.

  • Morphological and morphometric study of the androgenetic alopecic scalp using two‐ and three‐dimensional analysis comparing regional differences
    The British journal of dermatology, 2014
    Co-Authors: J.n. Kim, J.y. Lee, K.j. Shin, Young-chun Gil, Ki-seok Koh, W. C. Song
    Abstract:

    Summary Background Androgenetic (Male-Type) Alopecia (AGA) is caused by genetic and androgenetic effects. The progression of baldness results in smaller hair papillae, thinner hair and a shortened hair cycle. Alopecia occurs mainly in the frontal region and, to a lesser extent, in the occipital region. Objectives The morphological differences in the hair follicular units between the alopecic frontal scalp and the vertex and occipital regions were compared using cross-sectional histology and three-dimensional reconstruction. Methods Skin specimens were obtained from the frontal, vertex and occipital regions of 24 Male human cadavers with fully progressed AGA, and from the frontal region of 32 normal cadaveric scalps. These specimens were fixed, processed using routine histological methods, serially sectioned at a thickness of 10 μm and then stained with Masson's trichrome. The serial sections were reconstructed three-dimensionally using ‘Reconstruct’ software. Results The ratios between the numbers of terminal and vellus hairs in the frontal and occipital regions in the AGA scalps were 0·2 : 1 and 3·5 : 1, respectively. Almost all of the hair follicles in the frontal region were vellus hair follicles. The sebaceous gland and arrector pili muscle were larger in the frontal region than in the occipital region. Conclusions The morphology of the AGA scalp has been characterized. The terminal-to-vellus hair ratio in the occipital (normal) region was different from that in the frontal (alopecic) region. Moreover, sebaceous glands were larger in the frontal alopecic region than in the occipital region. These larger glands may be associated with other dermatological pathologies, such as seborrhoeic dermatitis.

De Castro J Jácome - One of the best experts on this subject based on the ideXlab platform.

  • Um caso raro de hiperandrogenismo tumor ovárico bilateral de células de Leydig.
    Ordem dos Médicos, 2010
    Co-Authors: Marcelino M, Nobre Ema, Conceição J, Lopes L, Vilar H, França Martins M, Carvalho A, André S, Horta A, De Castro J Jácome
    Abstract:

    The androgen-secreting tumors constitute fewer than 1% of ovarian tumors. Leydig cell tumor is one of the most common of this Type of lesion and it is usually benign, small and unilateral.A 67 year old woman was referred to the Endocrine clinic due to hirsutism (score 22 Ferriman-Gallwey) and Male Type Alopecia with 3 years of evolution and progressive worsening. Biochemically she had high levels of serum testosterone - 662 ng/dl (N < 62 ng/dl). Transvaginal ultrasonography and abdomen-pelvic CT scan didn't show any signs of adrenal or ovarian tumors. Bilateral oophorectomy was performed and histopathologic exam revealed bilateral Leydig cell tumors, measuring 1cm each. Four months after surgery, the patient had a marked improvement of the signs (score 3 Ferriman-Gallwey) and normalized testosterone levels (35.9 ng/dl).Androgen-secreting tumors are rare, but they should be excluded in cases of rapid onset of virilization and elevated androgen levels. Tumors are frequently undetectable by imaging techniques because of their small dimensions, exploratory surgery by a skilled team is frequently necessary and is often the best treatment for the majority of these cases. In this case report we present a rare case of bilateral Leydig cell tumor. Only five cases have been reported in the literature.The clinical history and the elevated levels of testosterone had suggested the presence of an androgen-producing tumor, despite the difficulty of the diagnosis on imaging techniques. Due to the fact that our patient was in a post-menopausal stage, we decided that the appropriate treatment would be bilateral oophorectomy. The histopathologic disclosed the diagnosis and allowed the patient's cure.The androgen-secreting tumors constitute fewer than 1% of ovarian tumors. Leydig cell tumor is one of the most common of this Type of lesion and it is usually benign, small and unilateral.A 67 year old woman was referred to the Endocrine clinic due to hirsutism (score 22 Ferriman-Gallwey) and Male Type Alopecia with 3 years of evolution and progressive worsening. Biochemically she had high levels of serum testosterone - 662 ng/dl (N < 62 ng/dl). Transvaginal ultrasonography and abdomen-pelvic CT scan didn't show any signs of adrenal or ovarian tumors. Bilateral oophorectomy was performed and histopathologic exam revealed bilateral Leydig cell tumors, measuring 1cm each. Four months after surgery, the patient had a marked improvement of the signs (score 3 Ferriman-Gallwey) and normalized testosterone levels (35.9 ng/dl).Androgen-secreting tumors are rare, but they should be excluded in cases of rapid onset of virilization and elevated androgen levels. Tumors are frequently undetectable by imaging techniques because of their small dimensions, exploratory surgery by a skilled team is frequently necessary and is often the best treatment for the majority of these cases. In this case report we present a rare case of bilateral Leydig cell tumor. Only five cases have been reported in the literature.The clinical history and the elevated levels of testosterone had suggested the presence of an androgen-producing tumor, despite the difficulty of the diagnosis on imaging techniques. Due to the fact that our patient was in a post-menopausal stage, we decided that the appropriate treatment would be bilateral oophorectomy. The histopathologic disclosed the diagnosis and allowed the patient's cure