The Experts below are selected from a list of 1384959 Experts worldwide ranked by ideXlab platform
Adam Raben - One of the best experts on this subject based on the ideXlab platform.
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freedom from local and regional failure of contralateral neck with ipsilateral neck radiotherapy for node positive tonsil cancer updated results of an institutional clinical Management Approach
Oral Oncology, 2015Co-Authors: Tu Dan, David Raben, Charles Schneider, Neil G Hockstein, Robert L Witt, Michael Dzeda, Jennifer F Cormier, Adam RabenAbstract:Summary Purpose To update the outcomes of an institutional clinical Management Approach using ipsilateral neck radiotherapy in the treatment of node-positive squamous cell carcinoma of the tonsil with a well-lateralized primary lesion. Methods and Materials Between August 2003 and April 2014, 61 consecutive patients with ipsilateral node-positive squamous cell carcinoma of the tonsil without involvement of the base of the tongue or midline soft palate were treated at a community hospital-based cancer center with radiotherapy to the primary site and ipsilateral neck. Overall survival, disease-free survival and freedom from contralateral failure were calculated. Results Median follow up was 37.2 months (range 4–121 months). Freedom from contralateral nodal failure at 5 years was 98% with one contralateral nodal failure noted. The patient underwent a salvage neck dissection and was treated with post-operative radiotherapy with no evidence of disease to date. 5-year overall survival (OS) was 92.4% and 5 year disease-free survival (DFS) was 86.7%. Conclusions This represents the single largest series reported from a community hospital-based cancer center in which lateralized tonsil cancers with N+ disease were treated with ipsilateral neck radiotherapy. In this carefully selected cohort of patients with well-lateralized tonsil cancers, the risk of contralateral nodal failure appears to be
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freedom from local and regional failure of contralateral neck with ipsilateral neck radiotherapy for node positive tonsil cancer results of a prospective Management Approach
International Journal of Radiation Oncology Biology Physics, 2009Co-Authors: Kyle E Rusthoven, David Raben, Robert L Witt, Charles J Schneider, Sarah Sammons, Adam RabenAbstract:Purpose To review the outcomes of a prospective Management Approach using ipsilateral neck radiotherapy in the treatment of node-positive squamous cell carcinoma of the tonsil with a well-lateralized primary lesion. Methods and Materials Between August 2003 and June 2007, 20 patients who presented with squamous cell carcinoma of the tonsil, without involvement of the base of the tongue or midline soft palate, and with Stage N1-N2b disease were prospectively treated with radiotherapy to the primary site and ipsilateral neck. In addition, 18 patients received concurrent chemotherapy. The actuarial freedom from contralateral nodal and in-field progression was determined. Acute and late toxicity were prospectively evaluated using the National Cancer Institute Common Terminology Criteria for Adverse Events, version 3, and Radiation Therapy Oncology Group criteria. Results The nodal disease was Stage N1 in 4 patients, N2a in 3 patients, and N2b in 13 patients. At a median follow-up 19 months (range, 12–40), no in-field or contralateral nodal recurrences had been observed. The 2-year freedom from distant metastasis rate was 87.4%. The actuarial 2-year disease-free and overall survival rates were both 79.5%. Late Radiation Therapy Oncology Group grade 2 xerostomia occurred in 1 patient (5%). No late Grade 3 or greater toxicity was observed. No patient was feeding tube dependent at their last follow-up visit. Conclusion In carefully selected patients with node-positive, lateralized tonsillar cancer, treatment of the ipsilateral neck and primary site does not appear to increase the risk of contralateral nodal failure and reduces late morbidity compared with historical controls. Although the outcomes with ipsilateral radiotherapy in the present series were promising, these findings require longer follow-up and validation in a larger patient cohort.
Mohamed Elbeltagy - One of the best experts on this subject based on the ideXlab platform.
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an energy Management Approach for renewable energy integration with power generation and water desalination
Renewable Energy, 2014Co-Authors: Malak T Alnory, Mohamed ElbeltagyAbstract:Abstract The share of the renewable energy sources (RES) in the global electricity market is substantially increasing as a result of the commitment of many countries to increase the contribution of the RES to their energy mix. However, the integration of RES in the electricity grid increases the complexity of the grid Management due to the variability and the intermittent nature of these energy sources. Energy storage solutions such as batteries offer either short-term storage that is not sufficient or longer period storage that is significantly expensive. This paper introduces an energy Management Approach which can be applied in the case of power and desalinated water generation. The Approach is based on mathematical optimization model which accounts for random variations in demands and energy supply. The Approach allows using desalination plants as a deferrable load to mitigate for the variability of the renewable energy supply and water and/or electricity demands. A mathematical linear programming model is developed to show the applicability of this idea and its effectiveness in reducing the impact of the uncertainty in the environment. The model is solved for the real world case of Saudi Arabia. The optimal solution accounts for random variations in the renewable energy supply and water and/or electricity demands while minimizing the total costs for generating water and power.
Malak T Alnory - One of the best experts on this subject based on the ideXlab platform.
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an energy Management Approach for renewable energy integration with power generation and water desalination
Renewable Energy, 2014Co-Authors: Malak T Alnory, Mohamed ElbeltagyAbstract:Abstract The share of the renewable energy sources (RES) in the global electricity market is substantially increasing as a result of the commitment of many countries to increase the contribution of the RES to their energy mix. However, the integration of RES in the electricity grid increases the complexity of the grid Management due to the variability and the intermittent nature of these energy sources. Energy storage solutions such as batteries offer either short-term storage that is not sufficient or longer period storage that is significantly expensive. This paper introduces an energy Management Approach which can be applied in the case of power and desalinated water generation. The Approach is based on mathematical optimization model which accounts for random variations in demands and energy supply. The Approach allows using desalination plants as a deferrable load to mitigate for the variability of the renewable energy supply and water and/or electricity demands. A mathematical linear programming model is developed to show the applicability of this idea and its effectiveness in reducing the impact of the uncertainty in the environment. The model is solved for the real world case of Saudi Arabia. The optimal solution accounts for random variations in the renewable energy supply and water and/or electricity demands while minimizing the total costs for generating water and power.
Grégoire Pau - One of the best experts on this subject based on the ideXlab platform.
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A Novel Energy Management Approach for Smart Homes Using Bluetooth Low Energy
IEEE Journal on Selected Areas in Communications, 2015Co-Authors: Massimo Collotta, Grégoire PauAbstract:Smart grids are an evolution of the existing electric distribution systems due to the growing demand of energy, the expansion in the use of renewable energy sources, and the development of novel and innovative information and communication technologies (ICT). The installation of systems based on wireless networks can play a key role in the extension of the smart grid toward smart homes, that can be deemed as one of the most important components of smart grids. In fact, monitoring and control applications, energy harvesting, and innovative metering methodologies through smart wireless devices are becoming increasingly important. This paper proposes a novel energy Management Approach for smart homes that combines a wireless network, based on bluetooth low energy (BLE), for communication among home appliances, with a home energy Management (HEM) scheme. The proposed Approach addresses the impact of standby appliances and high-power rating loads in peak hours to the energy consumption charges of consumers. Simulation results show that the proposed Approach is efficient in terms of reducing peak load demand and electricity consumption charges with an increase in the comfort level of consumers.
Robert L Witt - One of the best experts on this subject based on the ideXlab platform.
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freedom from local and regional failure of contralateral neck with ipsilateral neck radiotherapy for node positive tonsil cancer updated results of an institutional clinical Management Approach
Oral Oncology, 2015Co-Authors: Tu Dan, David Raben, Charles Schneider, Neil G Hockstein, Robert L Witt, Michael Dzeda, Jennifer F Cormier, Adam RabenAbstract:Summary Purpose To update the outcomes of an institutional clinical Management Approach using ipsilateral neck radiotherapy in the treatment of node-positive squamous cell carcinoma of the tonsil with a well-lateralized primary lesion. Methods and Materials Between August 2003 and April 2014, 61 consecutive patients with ipsilateral node-positive squamous cell carcinoma of the tonsil without involvement of the base of the tongue or midline soft palate were treated at a community hospital-based cancer center with radiotherapy to the primary site and ipsilateral neck. Overall survival, disease-free survival and freedom from contralateral failure were calculated. Results Median follow up was 37.2 months (range 4–121 months). Freedom from contralateral nodal failure at 5 years was 98% with one contralateral nodal failure noted. The patient underwent a salvage neck dissection and was treated with post-operative radiotherapy with no evidence of disease to date. 5-year overall survival (OS) was 92.4% and 5 year disease-free survival (DFS) was 86.7%. Conclusions This represents the single largest series reported from a community hospital-based cancer center in which lateralized tonsil cancers with N+ disease were treated with ipsilateral neck radiotherapy. In this carefully selected cohort of patients with well-lateralized tonsil cancers, the risk of contralateral nodal failure appears to be
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freedom from local and regional failure of contralateral neck with ipsilateral neck radiotherapy for node positive tonsil cancer results of a prospective Management Approach
International Journal of Radiation Oncology Biology Physics, 2009Co-Authors: Kyle E Rusthoven, David Raben, Robert L Witt, Charles J Schneider, Sarah Sammons, Adam RabenAbstract:Purpose To review the outcomes of a prospective Management Approach using ipsilateral neck radiotherapy in the treatment of node-positive squamous cell carcinoma of the tonsil with a well-lateralized primary lesion. Methods and Materials Between August 2003 and June 2007, 20 patients who presented with squamous cell carcinoma of the tonsil, without involvement of the base of the tongue or midline soft palate, and with Stage N1-N2b disease were prospectively treated with radiotherapy to the primary site and ipsilateral neck. In addition, 18 patients received concurrent chemotherapy. The actuarial freedom from contralateral nodal and in-field progression was determined. Acute and late toxicity were prospectively evaluated using the National Cancer Institute Common Terminology Criteria for Adverse Events, version 3, and Radiation Therapy Oncology Group criteria. Results The nodal disease was Stage N1 in 4 patients, N2a in 3 patients, and N2b in 13 patients. At a median follow-up 19 months (range, 12–40), no in-field or contralateral nodal recurrences had been observed. The 2-year freedom from distant metastasis rate was 87.4%. The actuarial 2-year disease-free and overall survival rates were both 79.5%. Late Radiation Therapy Oncology Group grade 2 xerostomia occurred in 1 patient (5%). No late Grade 3 or greater toxicity was observed. No patient was feeding tube dependent at their last follow-up visit. Conclusion In carefully selected patients with node-positive, lateralized tonsillar cancer, treatment of the ipsilateral neck and primary site does not appear to increase the risk of contralateral nodal failure and reduces late morbidity compared with historical controls. Although the outcomes with ipsilateral radiotherapy in the present series were promising, these findings require longer follow-up and validation in a larger patient cohort.
