The Experts below are selected from a list of 171 Experts worldwide ranked by ideXlab platform
K D Jo - One of the best experts on this subject based on the ideXlab platform.
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diffuse lesion in the splenium of the corpus callosum in patients with methyl bromide poisoning
Journal of Neurology Neurosurgery and Psychiatry, 2006Co-Authors: K Kang, Y M Song, K D JoAbstract:Imaging abnormalities of the splenium of the corpus callosum (SCC) are uncommon but have been described in various clinical conditions such as Marchiafava-Bignami Disease, trauma, infectious Diseases, acute disseminated encephalomyelitis, epilepsy, altitude sickness, hypoglycaemia, electrolyte abnormalities, leukodystrophy, and infarction, and following radiation therapy and chemotherapy.1,2 We have detected a diffuse lesion in the SCC of two patients with methyl bromide intoxication. The first case involved a previously healthy 31 year old man. He had worked in a fumigating plant spraying strawberries for 1 month prior to admission. Strawberries were fumigated with methyl bromide for 2 h in an enclosed room. After fumigation, the room was ventilated for 10 min with electric fans. Thereafter, the subject transferred the fumigated fruits to a warehouse. He worked for 3 h every other day. The subject reported experiencing intermittent nausea, dizziness, and ambulatory difficulty. On the day of hospital admission, the patient complained of general weakness, developed paraesthesia in the hands and feet, and was unable to recall daily events. He was admitted to the nearest hospital. The patient exhibited urinary incontinence, talked to himself, and was unable to walk unaided. He was transferred to our hospital 2 days later. Upon examination, all of the patient’s vital signs proved normal. However, he attempted to grab phantom objects in the air, sucked his fingers, and had difficulty …
Kenneth M Heilman - One of the best experts on this subject based on the ideXlab platform.
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left hemispatial neglect with a splenial lesion
Neurocase, 2018Co-Authors: Tigran Kesayan, Hamlet Gasoyan, Kenneth M HeilmanAbstract:With injury of the anterior two-thirds of the corpus callosum, each hemisphere's attentional bias to contralateral hemispace becomes manifest with each hand deviating ipsilaterally during line bisection tasks. Patients with infarctions in the right posterior cerebral artery distribution with occipital and splenial damage can also exhibit spatial neglect. The goal of this report is to learn the role of the splenium of the corpus callosum in mediating visuospatial attention. A right-handed woman with Marchiafava-Bignami Disease and damage to the splenium of her corpus callosum without evidence of a mesial frontal, parietal, or occipital injury was assessed for spatial neglect with line bisections. When bisecting lines in her left hemispace with her right hand, she deviated to the right, but revealed no major deviations when the line was place in the midline, in right hemispace, or when bisecting lines with her left hand. This patient provides evidence that damage to the splenium can induce a special form of asymmetrical spatial neglect. This asymmetry might be related to the disconnected right hemisphere's ability to allocate attention to both right and left hemispaces with the disconnected left hemisphere's ability to allocate attention to the right but not left hemispace.
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unilateral apraxic agraphia without ideomotor apraxia from a callosal lesion in a patient with Marchiafava Bignami Disease
Neurocase, 2018Co-Authors: Tigran Kesayan, Kenneth M HeilmanAbstract:ABSTRACTApraxic agraphia can be caused by left hemispheric cerebral lesions in the area that contains the spatial representations of the movements required to write, from a lesion in, or connections to, the frontal premotor cortex that converts these spatial representations to motor programs (Exner’s area). A right-handed woman with Marchiafava Bignami Disease and lesions of the genu and splenium of her corpus callosum had apraxic agraphia without ideomotor apraxia of her left. A disconnection of Exner’s area in the left hemisphere from the right hemisphere’s premotor and motor areas may have led to her inability to write with her left hand.
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unilateral apraxic agraphia without ideomotor apraxia from a callosal lesion in a patient with Marchiafava Bignami Disease
Neurocase, 2018Co-Authors: Tigran Kesayan, Kenneth M HeilmanAbstract:Apraxic agraphia can be caused by left hemispheric cerebral lesions in the area that contains the spatial representations of the movements required to write, from a lesion in, or connections to, th...
K Kang - One of the best experts on this subject based on the ideXlab platform.
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diffuse lesion in the splenium of the corpus callosum in patients with methyl bromide poisoning
Journal of Neurology Neurosurgery and Psychiatry, 2006Co-Authors: K Kang, Y M Song, K D JoAbstract:Imaging abnormalities of the splenium of the corpus callosum (SCC) are uncommon but have been described in various clinical conditions such as Marchiafava-Bignami Disease, trauma, infectious Diseases, acute disseminated encephalomyelitis, epilepsy, altitude sickness, hypoglycaemia, electrolyte abnormalities, leukodystrophy, and infarction, and following radiation therapy and chemotherapy.1,2 We have detected a diffuse lesion in the SCC of two patients with methyl bromide intoxication. The first case involved a previously healthy 31 year old man. He had worked in a fumigating plant spraying strawberries for 1 month prior to admission. Strawberries were fumigated with methyl bromide for 2 h in an enclosed room. After fumigation, the room was ventilated for 10 min with electric fans. Thereafter, the subject transferred the fumigated fruits to a warehouse. He worked for 3 h every other day. The subject reported experiencing intermittent nausea, dizziness, and ambulatory difficulty. On the day of hospital admission, the patient complained of general weakness, developed paraesthesia in the hands and feet, and was unable to recall daily events. He was admitted to the nearest hospital. The patient exhibited urinary incontinence, talked to himself, and was unable to walk unaided. He was transferred to our hospital 2 days later. Upon examination, all of the patient’s vital signs proved normal. However, he attempted to grab phantom objects in the air, sucked his fingers, and had difficulty …
Alexander Heinrich - One of the best experts on this subject based on the ideXlab platform.
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Marchiafava Bignami Disease diffusion weighted mri in corpus callosum and cortical lesions
Neurology, 2005Co-Authors: Alexander V Khaw, Alexander HeinrichAbstract:The clinical diagnosis of Marchiafava–Bignami Disease (MBD) can be difficult. Acute demyelination of the corpus callosum is characteristic of the Disease. The authors report the use of MR diffusion-weighted imaging (DWI) in six cases of acute MBD. They show that apparent diffusion coefficient restriction of the corpus callosum and cortical lesions were associated with a higher mortality rate and more severe cognitive sequelae.
Tigran Kesayan - One of the best experts on this subject based on the ideXlab platform.
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left hemispatial neglect with a splenial lesion
Neurocase, 2018Co-Authors: Tigran Kesayan, Hamlet Gasoyan, Kenneth M HeilmanAbstract:With injury of the anterior two-thirds of the corpus callosum, each hemisphere's attentional bias to contralateral hemispace becomes manifest with each hand deviating ipsilaterally during line bisection tasks. Patients with infarctions in the right posterior cerebral artery distribution with occipital and splenial damage can also exhibit spatial neglect. The goal of this report is to learn the role of the splenium of the corpus callosum in mediating visuospatial attention. A right-handed woman with Marchiafava-Bignami Disease and damage to the splenium of her corpus callosum without evidence of a mesial frontal, parietal, or occipital injury was assessed for spatial neglect with line bisections. When bisecting lines in her left hemispace with her right hand, she deviated to the right, but revealed no major deviations when the line was place in the midline, in right hemispace, or when bisecting lines with her left hand. This patient provides evidence that damage to the splenium can induce a special form of asymmetrical spatial neglect. This asymmetry might be related to the disconnected right hemisphere's ability to allocate attention to both right and left hemispaces with the disconnected left hemisphere's ability to allocate attention to the right but not left hemispace.
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unilateral apraxic agraphia without ideomotor apraxia from a callosal lesion in a patient with Marchiafava Bignami Disease
Neurocase, 2018Co-Authors: Tigran Kesayan, Kenneth M HeilmanAbstract:ABSTRACTApraxic agraphia can be caused by left hemispheric cerebral lesions in the area that contains the spatial representations of the movements required to write, from a lesion in, or connections to, the frontal premotor cortex that converts these spatial representations to motor programs (Exner’s area). A right-handed woman with Marchiafava Bignami Disease and lesions of the genu and splenium of her corpus callosum had apraxic agraphia without ideomotor apraxia of her left. A disconnection of Exner’s area in the left hemisphere from the right hemisphere’s premotor and motor areas may have led to her inability to write with her left hand.
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unilateral apraxic agraphia without ideomotor apraxia from a callosal lesion in a patient with Marchiafava Bignami Disease
Neurocase, 2018Co-Authors: Tigran Kesayan, Kenneth M HeilmanAbstract:Apraxic agraphia can be caused by left hemispheric cerebral lesions in the area that contains the spatial representations of the movements required to write, from a lesion in, or connections to, th...