The Experts below are selected from a list of 309 Experts worldwide ranked by ideXlab platform
Gianluca Giannarini - One of the best experts on this subject based on the ideXlab platform.
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robot assisted removal of a large seminal vesicle cyst with ipsilateral renal agenesis associated with an ectopic ureter and a mullerian cyst of the vas deferens
Urology, 2008Co-Authors: Cesare Selli, Stefano Cavalleri, Maurizio De Maria, Massimo Iafrate, Gianluca GiannariniAbstract:We present the first report of robot-assisted removal of a large seminal vesicle cyst with ipsilateral renal agenesis, associated with ectopic ureter and a Mullerian cyst of the vas deferens in a 39-year-old man. With the use of the same transperitoneal approach as robot-assisted laparoscopic radical prostatectomy and 5 ports, it was possible to remove this rare and complex malformation of the Mesonephric Duct that was causing pelvic pain and urogenital infection. The advantages over conventional laparoscopy consist of easier instrument manipulation, greater movement precision resulting in calibrated use of thermal energy, ease of suturing, and better visualization because of higher magnification and 3-dimensional imaging.
Robert D Oates - One of the best experts on this subject based on the ideXlab platform.
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unilateral renal agenesis associated with congenital bilateral absence of the vas deferens phenotypic findings and genetic considerations
Human Reproduction, 2001Co-Authors: Theresa J Mccallum, Jeff M Milunsky, R Munarriz, Richard E Carson, Hossein Sadeghinejad, Robert D OatesAbstract:An association between congenital bilateral absence of the vas deferens (CBAVD), normal renal anatomy and cystic fibrosis (CF) gene mutations is well established (CF/CBAVD). We postulate that unilateral renal agenesis (URA) and CBAVD (URA/CBAVD) may have a non-CF mutation-mediated genetic basis that leads to abnormal development of the entire Mesonephric Duct at a very early stage in embryo development (< or =7 weeks). The physical, laboratory and radiographic findings of men with URA/CBAVD (n = 17) and CF/CBAVD (n = 97) were compared; the fertilization and pregnancy rates in the URA/CBAVD population calculated, and the incidence of renal agenesis in immediate family members and offspring of men with URA/CBAVD analysed. No statistical differences could be identified within any of the above comparisons. The fertilization rate for the URA/CBAVD group was 58.2 +/- 26.3%. Eight infants and two fetuses had normal renal anatomy, while one terminated male fetus had bilateral renal and vasal agenesis. Thirty first-order relatives had normal renal units. Anatomical expression of the reproDuctive Ductal derivatives in men with URA/CBAVD and CF/CBAVD was similar, but the phenotypic outcome of the renal portion of the Mesonephric Duct was different. The potential for transmission of this fatal anomaly reinforces the need for prenatal ultrasounds with all pregnancies involving URA/CBAVD men.
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unilateral absence of the scrotal vas deferens associated with contralateral Mesonephric Duct anomalies resulting in infertility laboratory physical and radiographic findings and therapeutic alternatives
The Journal of Urology, 1993Co-Authors: Simon J Hall, Robert D OatesAbstract:Ten patients who presented for infertility had unilateral absence of the scrotal vas deferens and a contralateral Mesonephric Duct anomaly, including contralateral ejaculatory Duct or epididymal/vasal obstruction. The details of the physical examination, semen analysis and transrectal ultrasound led to an accurate preoperative diagnosis in each case. Therapeutic manipulations appropriate in this group included transurethral resection of the ejaculatory Duct, microscopic vasoepididymostomy and microsurgical sperm aspiration coupled with in vitro fertilization. Only 3 patients had ipsilateral renal agenesis or ectopia (30%), which is well below the stated percentage for patients with unilateral vasal agenesis (90%). An aberration in the proper sequence of Mesonephric embryological development may partly explain this bilateral constellation of abnormalities.
Cesare Selli - One of the best experts on this subject based on the ideXlab platform.
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robot assisted removal of a large seminal vesicle cyst with ipsilateral renal agenesis associated with an ectopic ureter and a mullerian cyst of the vas deferens
Urology, 2008Co-Authors: Cesare Selli, Stefano Cavalleri, Maurizio De Maria, Massimo Iafrate, Gianluca GiannariniAbstract:We present the first report of robot-assisted removal of a large seminal vesicle cyst with ipsilateral renal agenesis, associated with ectopic ureter and a Mullerian cyst of the vas deferens in a 39-year-old man. With the use of the same transperitoneal approach as robot-assisted laparoscopic radical prostatectomy and 5 ports, it was possible to remove this rare and complex malformation of the Mesonephric Duct that was causing pelvic pain and urogenital infection. The advantages over conventional laparoscopy consist of easier instrument manipulation, greater movement precision resulting in calibrated use of thermal energy, ease of suturing, and better visualization because of higher magnification and 3-dimensional imaging.
William C Torreggiani - One of the best experts on this subject based on the ideXlab platform.
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a unique radiological pentad of Mesonephric Duct abnormalities in a young man presenting with testicular swelling
British Journal of Radiology, 2008Co-Authors: Rowan G Casey, H Stunell, O Buckley, Robert Flynn, William C TorreggianiAbstract:Cystic dysplasia of the rete testis with associated ipsilateral renal agenesis is a very rare congenital abnormality, mainly described in the paediatric literature. In addition, the presence of a seminal vesicle cyst with ipsilateral renal agenesis is a rare but well-described entity. We present an adult who was found to have a unique pentad of Mesonephric Duct abnormalities on radiological imaging, including cystic dysplasia of the rete testis, seminal vesicle cyst, ipsilateral renal agenesis, partial hemitrigonal development and epididymal dilatation. We review and discuss the relevant literature of this case and discuss in detail the embryological basis for this unusual combination of findings.
Gerald G Long - One of the best experts on this subject based on the ideXlab platform.
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GG: Apparent Mesonephric Duct (rete anlage) origin for cysts and proliferative epithelial lesions in the mouse ovary. Toxicol Pathol 2002
2016Co-Authors: Gerald G LongAbstract:Ovaries and adjacent parovarian (mesovarial) tissues of CD-1 mice of various ages were examined to characterize cystic and proliferative epithelial lesions of the ovary and parovarian tissues. Ovaries and adjacent tissues from 6 mice each at approximately 3 and 8 months of age were processed for light microscopy and step-sections (50- l intervals) of the entire tissue were examined. Tissues were collected from 40 mice each at 16 through 24 months of age and 3 step sections per mouse were examined. Mesonephric Duct remnants were found in all mice at 3 and 8 months. Ducts were usually in the mesovarial adipose tissue and near or within the ovarian hilus and were often loosely associated with smooth muscle of the mesovarial ligament. The epithelium of the Ducts varied from low cuboidal to columnar, occasional individual cells were ciliated, and small papillary con gurations of epithelium were occasionally present. Ducts were dilated (>1 mm) more often in mice at 8 months compared to 3 months, and some were continuous with cystic spaces within the ovaries. As mice aged (16–24 months), dilation and cystic change in Ducts and associated compression of ovarian tissue away from the ovarian hilus became common. The epithelium of dilated Ducts was generally attened, but foci of cuboidal to columnar epithelium and/or occasional ciliated cells were present. Many Ducts contained foci of hyperplastic and/or hypertrophic epithelium, and papillary projections of epithelium were occasionally found. Some of the latter lesions were consistent with a diagnosis of papillary cystadenoma. Hyperplasia of associated bromuscular stroma was limited to a few apparently extraovarian Ducts. The results of this study indicate that remnant Mesonephric Ductular structures are common in and adjacent to the ovaries of CD-1 mice. As mice age, these Ducts become dilated and, in some, the epithelium becomes hyperplastic and/or hyperptrophic. These mesonephri c Duct remnants appear to be a common source of ovarian and parovarian cyts cyst
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apparent Mesonephric Duct rete anlage origin for cysts and proliferative epithelial lesions in the mouse ovary
Toxicologic Pathology, 2002Co-Authors: Gerald G LongAbstract:Ovaries and adjacent parovarian (mesovarial) tissues of CD-1 mice of various ages were examined to characterize cystic and proliferative epithelial lesions of the ovary and parovarian tissues. Ovaries and adjacent tissues from 6 mice each at approximately 3 and 8 months of age were processed for light microscopy and step-sections (50-micron intervals) of the entire tissue were examined. Tissues were collected from 40 mice each at 16 through 24 months of age and 3 step sections per mouse were examined. Mesonephric Duct remnants were found in all mice at 3 and 8 months. Ducts were usually in the mesovarial adipose tissue and near or within the ovarian hilus and were often loosely associated with smooth muscle of the mesovarial ligament. The epithelium of the Ducts varied from low cuboidal to columnar, occasional individual cells were ciliated, and small papillary configurations of epithelium were occasionally present. Ducts were dilated (> 1 mm) more often in mice at 8 months compared to 3 months, and some were continuous with cystic spaces within the ovaries. As mice aged (16-24 months), dilation and cystic change in Ducts and associated compression of ovarian tissue away from the ovarian hilus became common. The epithelium of dilated Ducts was generally flattened, but foci of cuboidal to columnar epithelium and/or occasional ciliated cells were present. Many Ducts contained foci of hyperplastic and/or hypertrophic epithelium, and papillary projections of epithelium were occasionally found. Some of the latter lesions were consistent with a diagnosis of papillary cystadenoma. Hyperplasia of associated fibromuscular stroma was limited to a few apparently extraovarian Ducts. The results of this study indicate that remnant Mesonephric Ductular structures are common in and adjacent to the ovaries of CD-1 mice. As mice age, these Ducts become dilated and, in some, the epithelium becomes hyperplastic and/or hyperptrophic. These Mesonephric Duct remnants appear to be a common source of ovarian and parovarian cyts cysts and epithelial neoplasms of the ovary in mice.