The Experts below are selected from a list of 213414 Experts worldwide ranked by ideXlab platform
Yoshiyuki Takei - One of the best experts on this subject based on the ideXlab platform.
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Alcohol consumption and Metabolic Syndrome
Hepatology Research, 2011Co-Authors: Naoki Fujita, Yoshiyuki TakeiAbstract:Drinking excessive amounts of alcohol regularly for years is toxic to almost every tissue of the body. On the other hand, epidemiological and clinical evidence shows that light-to-moderate drinking is associated with a reduced risk of coronary heart disease, total and ischemic stroke, and mortality. In the past two decades, Metabolic Syndrome, the combination of obesity, hypertension, dyslipidemia and hyperglycemia, are all also recognized as major cardiovascular risk factors, has given rise to much clinical and research attention, because of its high prevalence in the world. Therefore, it is of interest to evaluate the overall associations of alcohol consumption with the development of Metabolic Syndrome. Recently, the protective, detrimental or J-shaped associations have been reported between alcohol consumption and Metabolic Syndrome. This controversy may be due to the complex mechanistic relation between alcohol consumption and each component of Metabolic Syndrome, and almost all studies have various limitations and problem points. Prospective studies are therefore needed to confirm the association between alcohol consumption and prevalence of Metabolic Syndrome, and to assess the influence of alcohol drinking patterns and other possible factors, such as smoking, physical activity, socioeconomic status, education, occupation, diet and exercise. This article reviews the relation of alcohol consumption and components of Metabolic Syndrome, and discusses the epidemiological evidence for alcohol's putative vascular protective effects and plausible underlying biological mechanisms.
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Alcohol consumption and Metabolic Syndrome
Japanese journal of alcohol studies & drug dependence, 2010Co-Authors: Naoki Fujita, Yoshiyuki TakeiAbstract:Drinking excessive amounts of alcohol regularly for years is toxic to almost every tissue of the body. On the other hand, epidemiological and clinical evidence shows that light-to-moderate drinking is associated with a reduced risk of coronary heart disease, total and ischemic stroke, and mortality. In the past two decades, Metabolic Syndrome, the combination of obesity, hypertension, dyslipidemia and hyperglycemia, all are also recognized as major cardiovascular risk factors, has given rise to much clinical and research attention, because of its high prevalence in the world. Therefore, it is of interest to evaluate the overall associations of alcohol consumption with the development of the Metabolic Syndrome. Recently, the protective, detrimental, or J-shaped associations have been reported between alcohol consumption and the Metabolic Syndrome. This controversy may be due to the complex mechanistic relation between alcohol consumption and each component of Metabolic Syndrome, and almost all studies have various limitations and problem points. Prospective studies are therefore needed to confirm the association between alcohol consumption and prevalence of Metabolic Syndrome, and to assess the influence of alcohol drinking patterns and other possible factors, such as smoking, physical activity, socio-economic status, education, occupation, diet, and exercise. This article reviews the relation of alcohol consumption and components of the Metabolic Syndrome, and discusses the epidemiological evidence for alcohol's putative vascular protective effects and plausible underlying biological mechanisms.
Naoki Fujita - One of the best experts on this subject based on the ideXlab platform.
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Alcohol consumption and Metabolic Syndrome
Hepatology Research, 2011Co-Authors: Naoki Fujita, Yoshiyuki TakeiAbstract:Drinking excessive amounts of alcohol regularly for years is toxic to almost every tissue of the body. On the other hand, epidemiological and clinical evidence shows that light-to-moderate drinking is associated with a reduced risk of coronary heart disease, total and ischemic stroke, and mortality. In the past two decades, Metabolic Syndrome, the combination of obesity, hypertension, dyslipidemia and hyperglycemia, are all also recognized as major cardiovascular risk factors, has given rise to much clinical and research attention, because of its high prevalence in the world. Therefore, it is of interest to evaluate the overall associations of alcohol consumption with the development of Metabolic Syndrome. Recently, the protective, detrimental or J-shaped associations have been reported between alcohol consumption and Metabolic Syndrome. This controversy may be due to the complex mechanistic relation between alcohol consumption and each component of Metabolic Syndrome, and almost all studies have various limitations and problem points. Prospective studies are therefore needed to confirm the association between alcohol consumption and prevalence of Metabolic Syndrome, and to assess the influence of alcohol drinking patterns and other possible factors, such as smoking, physical activity, socioeconomic status, education, occupation, diet and exercise. This article reviews the relation of alcohol consumption and components of Metabolic Syndrome, and discusses the epidemiological evidence for alcohol's putative vascular protective effects and plausible underlying biological mechanisms.
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Alcohol consumption and Metabolic Syndrome
Japanese journal of alcohol studies & drug dependence, 2010Co-Authors: Naoki Fujita, Yoshiyuki TakeiAbstract:Drinking excessive amounts of alcohol regularly for years is toxic to almost every tissue of the body. On the other hand, epidemiological and clinical evidence shows that light-to-moderate drinking is associated with a reduced risk of coronary heart disease, total and ischemic stroke, and mortality. In the past two decades, Metabolic Syndrome, the combination of obesity, hypertension, dyslipidemia and hyperglycemia, all are also recognized as major cardiovascular risk factors, has given rise to much clinical and research attention, because of its high prevalence in the world. Therefore, it is of interest to evaluate the overall associations of alcohol consumption with the development of the Metabolic Syndrome. Recently, the protective, detrimental, or J-shaped associations have been reported between alcohol consumption and the Metabolic Syndrome. This controversy may be due to the complex mechanistic relation between alcohol consumption and each component of Metabolic Syndrome, and almost all studies have various limitations and problem points. Prospective studies are therefore needed to confirm the association between alcohol consumption and prevalence of Metabolic Syndrome, and to assess the influence of alcohol drinking patterns and other possible factors, such as smoking, physical activity, socio-economic status, education, occupation, diet, and exercise. This article reviews the relation of alcohol consumption and components of the Metabolic Syndrome, and discusses the epidemiological evidence for alcohol's putative vascular protective effects and plausible underlying biological mechanisms.
Cao Zhong-chao - One of the best experts on this subject based on the ideXlab platform.
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Metabolic Syndrome and Hypertension
Inner Mongolia Medical Journal, 2007Co-Authors: Cao Zhong-chaoAbstract:Objective:To inquire the relation between hypertension and Metabolic Syndrome,then to evalulate the role of hypertension.Method:Reading the literature about hypertension and Metabolic Syndrome,then summarizing them.Result:The constitutes of Metabolic Syndrome are varied,but hypertension always is the most composition of Metabolic Syndrome.Conclusion:In every constitute hypertension always is in a important condition and is the most dangerous to the system of heart,brain and vascular.
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Renal Dysfunction in the Metabolic Syndrome
Inner Mongolia Medical Journal, 2007Co-Authors: Cao Zhong-chaoAbstract:Metabolic Syndrome iS multi-Metabolic abnormalities,including obesity,hypertension,plasma glucose abnormalities,dyslipidemia leading to atherosclerosis and so on.At present,results of researches indicate that Metabolic Syndrome also causes and aggravates renal dysfunction and thus it can be seen there is closed relation between Metabolic Syndrome and kidney disease.In this review,we discussed the renal dysfunction in the Metabolic Syndrome.
Tracie L. Miller - One of the best experts on this subject based on the ideXlab platform.
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Pediatric Metabolic Syndrome - Pediatric Metabolic Syndrome: Comprehensive clinical review and related health issues
2012Co-Authors: Steven E. Lipshultz, Sarah E. Messiah, Tracie L. MillerAbstract:Why should we write a book on pediatric Metabolic Syndrome? Commentaries from Worldwide Experts.- Epidemiology of the Metabolic Syndrome in Youth: A Population-to-Clinical-Based Perspective.-Perinatal Epidemiology of Metabolic Syndrome Risk Factors.- Metabolic Syndrome in Childhood as a Risk Factor for Type 2 Diabetes.- Effects of Metabolic Syndrome on Atherosclerosis in Childhood.- Metabolic Syndrome and Associated Kidney Disease.- Metabolic Syndrome and Related Liver Diseases.- The Relationship between Asthma, Sleep Apnea and other Respiratory Disorders and Childhood Metabolic Syndrome.- The Relationship between Components of the Metabolic Syndrome and Bone Health.- The Relationship of Childhood Obesity with Cardiomyopathy and Heart Failure.- Childhood Metabolic Syndrome and Cancer Risk.- Neurocognitive and Psychological Correlates of Metabolic Syndrome in Childhood.- Genomics of Pediatric Metabolic Syndrome.- Physical Activity Assessment and Intervention.- Nutritional Evaluation and Intervention.- Pharmacological Therapies of Metabolic Syndrome.- Bariatric Surgery to Reverse Metabolic Syndrome in Adolescents.- Moving Clinic- and Community-based Practice into Policy to Address Child Healthy Weight (and vice versa).
Julia Steinberger - One of the best experts on this subject based on the ideXlab platform.
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The pediatric Metabolic Syndrome.
Minerva medica, 2008Co-Authors: J. A. Morrison, Earl S. Ford, Julia SteinbergerAbstract:The Metabolic Syndrome is a frequent subject of attention, discussion, and debate in medical research, because of its linkages to the growing problem of obesity on the one hand and both diabetes mellitus and cardiovascular disease on the other. It is also the grounds for contention, as respected researchers disagree on its definition and even on its validity as a construct. This clustering of obesity, dyslipidemia, elevated blood pressure, impaired glucose metabolism, and acute phase reactants can be seen in children as well as in adults. There are at least five definitions of adult Metabolic Syndrome promulgated by different societies and organizations, and as many as 40 different definitions of the Syndrome have been used in pediatric studies. In 2007, the International Diabetes Federation published a definition of pediatric Metabolic Syndrome; whether it unifies the field remains to be seen. In addition, long term cohort studies have furnished data showing that clusters of the factors used to identify Metabolic Syndrome do predict the presence of type 2 diabetes and cardiovascular disease defined as myocardial infarction, stroke, coronary artery bypass graft, and/or positive angiogram. In addition, longitudinal studies have demonstrated compromised vascular function in young adults with Metabolic Syndrome, variously defined, as children and adolescents. This review discusses the background and development of the concept of a Metabolic Syndrome, the inter-relationships among its constitutive elements, the debates surrounding the uses of the concept and possible treatment avenues.