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Melanie J Charity - One of the best experts on this subject based on the ideXlab platform.
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girls transition from participation in a Modified sport Program to club sport competition a study of longitudinal patterns and correlates
BMC Public Health, 2018Co-Authors: Rochelle Eime, Jack T Harvey, Melanie J CharityAbstract:Participation in sport is very popular for young children. Many children participate in entry-level Modified sports Programs. These Programs are Modified to match the developmental capacity of children and are aimed at development of fundamental motor skills and sport-specific skills, rather than competition. There is limited research on the longitudinal tracking of children in these Programs and into club-based competition. Research suggests that most children drop-out of the sport and do not transition into club-based competition. Furthermore, more females than males drop-out of sport. The aim of this study is to investigate longitudinally, the patterns and demographic predictors of children’s transition from Modified sport Programs to club sport competition for females. This study analysed sport participation for females in a popular Australian, predominantly female, sport. Players of the Modified sports Program were followed over 4 years to determine their pattern of transition: transition to junior player status, withdraw from the sport, or continue in the Modified Program. Pattern of transition was compared across age (4–10), geographical region (metropolitan/non-metropolitan) and socio-economic status (SES). Logistic regression was used to model the effect of the three factors on the likelihood of transition. A total of 13,760 female children (aged 4–10) participated in the Modified sport in the first year. The majority (59%) transitioned from the Modified sport Program and into club competition. However the rate of transition varied with age, residential location and socio-economic status, and there was an interaction between region and SES, with SES having a significant influence on transition in the metropolitan region. The peak sport entry age with the highest rates of transition was 7–9 years. This study demonstrated that whilst the majority of female participants continued participantion and tranisitioned from the Modified sport Program and into club competition, the strongest correlate of transition was age of entry, with transition rate peaking among those who commenced at age 7–9 years. It is recommended that, in order to maximise continued participation, sport policy and strategic developments should consider the possibility that targeting the very young is not the optimum recruitment strategy for fostering continued sport participation.
Rochelle Eime - One of the best experts on this subject based on the ideXlab platform.
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girls transition from participation in a Modified sport Program to club sport competition a study of longitudinal patterns and correlates
BMC Public Health, 2018Co-Authors: Rochelle Eime, Jack T Harvey, Melanie J CharityAbstract:Participation in sport is very popular for young children. Many children participate in entry-level Modified sports Programs. These Programs are Modified to match the developmental capacity of children and are aimed at development of fundamental motor skills and sport-specific skills, rather than competition. There is limited research on the longitudinal tracking of children in these Programs and into club-based competition. Research suggests that most children drop-out of the sport and do not transition into club-based competition. Furthermore, more females than males drop-out of sport. The aim of this study is to investigate longitudinally, the patterns and demographic predictors of children’s transition from Modified sport Programs to club sport competition for females. This study analysed sport participation for females in a popular Australian, predominantly female, sport. Players of the Modified sports Program were followed over 4 years to determine their pattern of transition: transition to junior player status, withdraw from the sport, or continue in the Modified Program. Pattern of transition was compared across age (4–10), geographical region (metropolitan/non-metropolitan) and socio-economic status (SES). Logistic regression was used to model the effect of the three factors on the likelihood of transition. A total of 13,760 female children (aged 4–10) participated in the Modified sport in the first year. The majority (59%) transitioned from the Modified sport Program and into club competition. However the rate of transition varied with age, residential location and socio-economic status, and there was an interaction between region and SES, with SES having a significant influence on transition in the metropolitan region. The peak sport entry age with the highest rates of transition was 7–9 years. This study demonstrated that whilst the majority of female participants continued participantion and tranisitioned from the Modified sport Program and into club competition, the strongest correlate of transition was age of entry, with transition rate peaking among those who commenced at age 7–9 years. It is recommended that, in order to maximise continued participation, sport policy and strategic developments should consider the possibility that targeting the very young is not the optimum recruitment strategy for fostering continued sport participation.
Jack T Harvey - One of the best experts on this subject based on the ideXlab platform.
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girls transition from participation in a Modified sport Program to club sport competition a study of longitudinal patterns and correlates
BMC Public Health, 2018Co-Authors: Rochelle Eime, Jack T Harvey, Melanie J CharityAbstract:Participation in sport is very popular for young children. Many children participate in entry-level Modified sports Programs. These Programs are Modified to match the developmental capacity of children and are aimed at development of fundamental motor skills and sport-specific skills, rather than competition. There is limited research on the longitudinal tracking of children in these Programs and into club-based competition. Research suggests that most children drop-out of the sport and do not transition into club-based competition. Furthermore, more females than males drop-out of sport. The aim of this study is to investigate longitudinally, the patterns and demographic predictors of children’s transition from Modified sport Programs to club sport competition for females. This study analysed sport participation for females in a popular Australian, predominantly female, sport. Players of the Modified sports Program were followed over 4 years to determine their pattern of transition: transition to junior player status, withdraw from the sport, or continue in the Modified Program. Pattern of transition was compared across age (4–10), geographical region (metropolitan/non-metropolitan) and socio-economic status (SES). Logistic regression was used to model the effect of the three factors on the likelihood of transition. A total of 13,760 female children (aged 4–10) participated in the Modified sport in the first year. The majority (59%) transitioned from the Modified sport Program and into club competition. However the rate of transition varied with age, residential location and socio-economic status, and there was an interaction between region and SES, with SES having a significant influence on transition in the metropolitan region. The peak sport entry age with the highest rates of transition was 7–9 years. This study demonstrated that whilst the majority of female participants continued participantion and tranisitioned from the Modified sport Program and into club competition, the strongest correlate of transition was age of entry, with transition rate peaking among those who commenced at age 7–9 years. It is recommended that, in order to maximise continued participation, sport policy and strategic developments should consider the possibility that targeting the very young is not the optimum recruitment strategy for fostering continued sport participation.
Tatyana Obukhova - One of the best experts on this subject based on the ideXlab platform.
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First experience of using Brentuximab vedotin and Modified Program NHL-BFM-90 in the front-line treatment of patient with anaplastic large-cell lymphoma: a case report and a review of literature.
Terapevticheskii arkhiv, 2018Co-Authors: N G Chernova, Tatyana Obukhova, D. S. Badmazhapova, M N Sinitsyna, L A Grebenyuk, Yu. V. Sidorova, I E Kostina, Alla M. Kovrigina, Andrey SudarikovAbstract:Nodal anaplastic ALK-negative large cell lymphoma (nALCL, ALK-) is a Т-cell lymphoma that is characterized by aggressive clinical course and low sensitivity to СНОР (cyclophosphamide, doxorubicin, vincristine, prednisolone) and other chemotherapy regimen. In the article we present a literature review and describe our clinical case of nALCL, ALK-. For the first time a combination of Brentuximab vedotin with Modified Program NHL-BFM-90 was used as a first-line therapy. As a result of immunochemotherapy a complete antineoplastic effect was obtained. For consolidation of this effect high-dose chemotherapy with following autologous blood stem cell transplantation was performed. The chosen treatment tactics allowed to achieve a complete remission in a medium risk group patient.
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Pilot experience in the treatment of poor-prognosis primary diffuse large-B-cell lymphosarcoma of the bones and soft tissues with a Modified Program NHL-BFM-90
Terapevticheskii Arkhiv, 2009Co-Authors: Anna Konstantinovna Morozova, Aminat U. Magomedova, Tatyana Obukhova, Морозова Анна Константиновна, Звонков Евгений Евгеньевич, A M Kremenetskaya, Кременецкая Александра Михайловна, Магомедова Аминат Умурасхабовна, Обухова Татьяна НикифоровнаAbstract:Aim. To evaluate efficacy of intensive Modified Program NHL-BFM-90 (mNHL-BFM-90) in adult poor-prognosis patients with diffuse large B-cell lymphosarcoma (DLBCL) of the bones and soft tissues. Material and methods. The mNHL-BFM-90 Program was used in the treatment of 3 male and 2 female patients aged 17-69 years (median 42 years). Four patients had DLBCL of the bones and one patient - DLBCL of the soft tissues. All the patients had tumors more than 10 cm in size. B-symptoms, a high concentration of lactate dehydrogenase (LDG) were registered in 3 patients. One patient had stage IE by Ann-Arbor, two - stage IIE (involvement of regional lymph nodes), two - stage ME (multiple bone lesions). A total of 4-6 blocks of polychemotherapy according to mNHL-BFM-90 Program were performed. Results. Complete remissions were achieved in all the patients. They had no recurrences after 6 to 20 month (median 13 months) follow-up. Conclusion. Positive results of the Program mNHL-BFM-90 in poor-prognosis patients with DLBCL of the bones and tissues necessitate further studies of this therapy.
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First experience of using Modified Program NHL-BFM-90 for the treatment of primary diffuse large-B-cell lymphosarcoma of the bones and soft tissues with poor-prognosis
Terapevticheskii arkhiv, 2009Co-Authors: Aminat U. Magomedova, Tatyana ObukhovaAbstract:AIM To evaluate efficacy of intensive Modified Program NHL-BFM-90 (mNHL-BFM-90) in adult poor-prognosis patients with diffuse large B-cell lymphosarcoma (DLBCL) of the bones and soft tissues. MATERIAL AND METHODS The mNHL-BFM-90 Program was used in the treatment of 3 male and 2 female patients aged 17-69 years (median 42 years). Four patients had DLBCL of the bones and one patient--DLBCL of the soft tissues. All the patients had tumors more than 10 cm in size. B-symptoms, a high concentration of lactate dehydrogenase (LDG) were registered in 3 patients. One patient had stage IE by Ann-Arbor, two--stage IIE (involvement of regional lymph nodes), two--stage ME (multiple bone lesions). A total of 4-6 blocks of polychemotherapy according to mNHL-BFM-90 Program were performed. RESULTS Complete remissions were achieved in all the patients. They had no recurrences after 6 to 20 month (median 13 months) follow-up. CONCLUSION Positive results of the Program mNHL-BFM-90 in poor-prognosis patients with DLBCL of the bones and tissues necessitate further studies of this therapy.
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The Modified Program NHL-BFM-90 in the treatment of patients with diffuse large B-cell lymphosarcoma
Terapevticheskii arkhiv, 2006Co-Authors: Aminat U. Magomedova, Tatyana ObukhovaAbstract:AIM: To investigate efficacy of the Modified protocol NHL-BFM-90 in patients with diffuse large B-cell lymphosarcoma (DLBCLS). MATERIAL AND METHODS: A total of 13 DLBCLS patients with stage II-IV of the disease with affection of lymph nodes at the disease onset (nodal lesion) and stage II with tumor size more than 10 cm (bulky disease) received first-line treatment according to the Modified Program NHL-BFM-90 from 2002 to 2005. The diagnosis was made by WHO criteria. RESULTS: A complete remission was achieved in 76.9% patients. Resistance to therapy was observed in the patients with bone marrow affection. The 2.5-year overall survival was 74%, 2-year event-free survival was 75% (the events were recurrence and resistance). Follow-up continued from 5 to 47 months. CONCLUSION: The efficacy of the Modified protocol NHL-BFM-90 in DLBCLS patients with stage III-IV of the "nodal" disease and stage II of the "bulky" disease was high.
Marc Witteman - One of the best experts on this subject based on the ideXlab platform.
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Fault Attacks on Secure Embedded Software: Threats, Design, and Evaluation
Journal of Hardware and Systems Security, 2018Co-Authors: Bilgiday Yuce, Patrick Schaumont, Marc WittemanAbstract:Embedded software is developed under the assumption that hardware execution is always correct. Fault attacks break and exploit that assumption. Through the careful introduction of targeted faults, an adversary modifies the control flow or data flow integrity of software. The Modified Program execution is then analyzed and used as a source of information leakage, or as a mechanism for privilege escalation. Due to the increasing complexity of modern embedded systems, and due to the difficulty of guaranteeing correct hardware execution even under a weak adversary, fault attacks are a growing threat. For example, the assumption that an adversary has to be close to the physical execution of software, in order to inject an exploitable fault into hardware, has repeatedly been shown to be incorrect. This article is a review on hardware-based fault attacks on software, with emphasis on the context of embedded systems. We present a detailed discussion of the anatomy of a fault attack, and we make a review of fault attack evaluation techniques. The paper emphasizes the perspective from the attacker, rather than the perspective of countermeasure development. However, we emphasize that improvements to countermeasures often build on insight into the attacks.