The Experts below are selected from a list of 2196 Experts worldwide ranked by ideXlab platform

Latief Najar - One of the best experts on this subject based on the ideXlab platform.

  • Multiple Dentigerous Cysts as a Rare Presentation of Maroteaux-Lamy Syndrome.
    Annals of Maxillofacial Surgery, 2017
    Co-Authors: Ajaz Shah, Tajamul Hakim, Shahid Farooq, Mubashir Younis, Shamina Kosar, Altaf H. Malik, Latief Najar
    Abstract:

    Maroteaux-Lamy syndrome is one of the genetic disorders involving disturbances in mucopolysaccaride metabolism, due to deficiency of aryl sulfatase-B which leads to accumulation of dermatan sulfate in tissues and their excretion in urine. The diseases has several oral and dental manifestations, is first diagnosed on the basis of clinical findings. It is characterized by coarse facial features, normal intelligence, organomegaly, enlarged head, short neck, corneal clouding, enlarged tongue, and prominent metachromatic inclusions in leukocytes. Death is usually a result of either respiratory tract infection or cardiac disease, which is caused by the deposition of Mucopolysaccharides. An 18-year-old with Maroteaux-Lamy syndrome is described in this article with multiple dentigerous cysts as the first presentation.

Chaim Lotan - One of the best experts on this subject based on the ideXlab platform.

  • hypothyroidism induced myocardial damage and heart failure an overlooked entity
    Cardiovascular Pathology, 2009
    Co-Authors: Mony Shuvy, Oshrat Tayer E Shifman, Samir Nusair, Orit Pappo, Chaim Lotan
    Abstract:

    Abstract Background Hypothyroid state may induce cardiac muscle impairment such as diastolic dysfunction and abnormal relaxation time. Advanced heart failure in hypothyroid patients has been described only in severe symptomatic cases, mostly during myxedematous coma. Methods and Results We describe an unusual case of asymptomatic patient with hypothyroidism who presented with severely reduced cardiac function with elevated cardiac enzymes reflecting significant myocardial injury. Comprehensive evaluation for heart failure was suggestive only for long-standing untreated hypothyroidism. Endomyocadial biopsy demonstrated unique histological findings of Mucopolysaccharide accumulation attributed to hypothyroid state. Conclusions Asymptomatic hypothyroidism may cause severe reduction in cardiac function accompanied with elevated cardiac enzymes. To our knowledge, this is the first description of human myocardial biopsy revealing Mucopolysaccharide accumulation attributed to hypothyroid state.

  • case report hypothyroidism induced myocardial damage and heart failure an overlooked entity
    2009
    Co-Authors: Mony Shuvy, Oshrat Tayer E Shifman, Samir Nusair, Orit Pappo, Chaim Lotan
    Abstract:

    Background: Hypothyroid state may induce cardiac muscle impairment such as diastolic dysfunction and abnormal relaxation time. Advanced heart failure in hypothyroid patients has been described only in severe symptomatic cases, mostly during myxedematous coma. Methods and Results: We describe an unusual case of asymptomatic patient with hypothyroidism who presented with severely reduced cardiac function with elevated cardiac enzymes reflecting significant myocardial injury. Comprehensive evaluation for heart failure was suggestive only for long-standing untreated hypothyroidism. Endomyocadial biopsy demonstrated unique histological findings of Mucopolysaccharide accumulation attributed to hypothyroid state. Conclusions: Asymptomatic hypothyroidism may cause severe reduction in cardiac function accompanied with elevated cardiac enzymes. To our knowledge, this is the first description of human myocardial biopsy revealing Mucopolysaccharide accumulation attributed to hypothyroid state. © 2009 Elsevier Inc. All rights reserved.

Ajaz Shah - One of the best experts on this subject based on the ideXlab platform.

  • Multiple Dentigerous Cysts as a Rare Presentation of Maroteaux-Lamy Syndrome.
    Annals of Maxillofacial Surgery, 2017
    Co-Authors: Ajaz Shah, Tajamul Hakim, Shahid Farooq, Mubashir Younis, Shamina Kosar, Altaf H. Malik, Latief Najar
    Abstract:

    Maroteaux-Lamy syndrome is one of the genetic disorders involving disturbances in mucopolysaccaride metabolism, due to deficiency of aryl sulfatase-B which leads to accumulation of dermatan sulfate in tissues and their excretion in urine. The diseases has several oral and dental manifestations, is first diagnosed on the basis of clinical findings. It is characterized by coarse facial features, normal intelligence, organomegaly, enlarged head, short neck, corneal clouding, enlarged tongue, and prominent metachromatic inclusions in leukocytes. Death is usually a result of either respiratory tract infection or cardiac disease, which is caused by the deposition of Mucopolysaccharides. An 18-year-old with Maroteaux-Lamy syndrome is described in this article with multiple dentigerous cysts as the first presentation.

Nuray Bayar Muluk - One of the best experts on this subject based on the ideXlab platform.

Mony Shuvy - One of the best experts on this subject based on the ideXlab platform.

  • hypothyroidism induced myocardial damage and heart failure an overlooked entity
    Cardiovascular Pathology, 2009
    Co-Authors: Mony Shuvy, Oshrat Tayer E Shifman, Samir Nusair, Orit Pappo, Chaim Lotan
    Abstract:

    Abstract Background Hypothyroid state may induce cardiac muscle impairment such as diastolic dysfunction and abnormal relaxation time. Advanced heart failure in hypothyroid patients has been described only in severe symptomatic cases, mostly during myxedematous coma. Methods and Results We describe an unusual case of asymptomatic patient with hypothyroidism who presented with severely reduced cardiac function with elevated cardiac enzymes reflecting significant myocardial injury. Comprehensive evaluation for heart failure was suggestive only for long-standing untreated hypothyroidism. Endomyocadial biopsy demonstrated unique histological findings of Mucopolysaccharide accumulation attributed to hypothyroid state. Conclusions Asymptomatic hypothyroidism may cause severe reduction in cardiac function accompanied with elevated cardiac enzymes. To our knowledge, this is the first description of human myocardial biopsy revealing Mucopolysaccharide accumulation attributed to hypothyroid state.

  • case report hypothyroidism induced myocardial damage and heart failure an overlooked entity
    2009
    Co-Authors: Mony Shuvy, Oshrat Tayer E Shifman, Samir Nusair, Orit Pappo, Chaim Lotan
    Abstract:

    Background: Hypothyroid state may induce cardiac muscle impairment such as diastolic dysfunction and abnormal relaxation time. Advanced heart failure in hypothyroid patients has been described only in severe symptomatic cases, mostly during myxedematous coma. Methods and Results: We describe an unusual case of asymptomatic patient with hypothyroidism who presented with severely reduced cardiac function with elevated cardiac enzymes reflecting significant myocardial injury. Comprehensive evaluation for heart failure was suggestive only for long-standing untreated hypothyroidism. Endomyocadial biopsy demonstrated unique histological findings of Mucopolysaccharide accumulation attributed to hypothyroid state. Conclusions: Asymptomatic hypothyroidism may cause severe reduction in cardiac function accompanied with elevated cardiac enzymes. To our knowledge, this is the first description of human myocardial biopsy revealing Mucopolysaccharide accumulation attributed to hypothyroid state. © 2009 Elsevier Inc. All rights reserved.