The Experts below are selected from a list of 20454 Experts worldwide ranked by ideXlab platform
Rodney Jacobs - One of the best experts on this subject based on the ideXlab platform.
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Successful treatment of Mucosa-Associated Lymphoid Tissue lymphoma of the rectum with radiation therapy: report of a case.
Diseases of the colon and rectum, 2008Co-Authors: Marcus Foo, M. Chao, Peter Gibbs, Michael Guiney, Rodney JacobsAbstract:We report a case of Stage IE Mucosa-Associated Lymphoid Tissue lymphoma arising in the rectum, which was successfully treated with radiotherapy. A 60-year-old man had several months of altered bowel habit with rectal bleeding and was found to have a large rectal tumor with no evidence of distant spread. Histologic studies showed this to be a Mucosa-Associated Lymphoid Tissue lymphoma. The patient received 45 Gy in 25 fractions with external beam radiotherapy during 5 weeks. The treatment was well tolerated and review at 41 months revealed no evidence of recurrence.
Christiane Copie-bergman - One of the best experts on this subject based on the ideXlab platform.
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Colonic Mucosa-Associated Lymphoid Tissue lymphoma: a case series.
Leukemia & lymphoma, 2019Co-Authors: Jenny Tannoury, Aurelien Amiot, François Lemonnier, Jehan Dupuis, Charlotte Gagniere, Karim Belhadj, Fabien Le Bras, Iradj Sobhani, Corinne Haioun, Christiane Copie-bergmanAbstract:Primary colonic Mucosa-Associated Lymphoid Tissue (MALT) lymphoma accounts for less than 0.5% of all colon cancers. We report 9 cases of colonic MALT lymphomas (median follow up: 9 [IQR 1–26] years...
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Pulmonary Mucosa-Associated Lymphoid Tissue lymphoma revisited
European Respiratory Journal, 2016Co-Authors: Raphael Borie, Catherine Thieblemont, Christiane Copie-bergman, Marie Wislez, Martine Antoine, Jacques CadranelAbstract:This general review sought to clarify the pathophysiological, diagnostic, prognostic, and therapeutic features of pulmonary Mucosa-Associated Lymphoid Tissue (MALT) lymphoma. MALT lymphoma is the most common pulmonary B-cell lymphoma, which usually occurs in the context of acquired MALT. The disease is slow-growing with an asymptomatic chronic alveolar opacity visible on radiography. Diagnosis requires Tissue samples that should be retrieved using minimally invasive techniques, such as bronchoscopy or computed tomography-guided biopsies. The pathophysiology includes cytogenetic abnormalities and autoimmune diseases, whereas an association with a chronic pulmonary infection is still suspected but not yet demonstrated. Disease prognosis is typically excellent and the current available treatments are discussed in this review, including the decision not to treat, surgery, and single- or double-agent chemotherapy.
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Primary Mucosa-Associated Lymphoid Tissue lymphoma of the gallbladder: report of a case harboring API2/MALT1 gene fusion
Human pathology, 2009Co-Authors: Bettina Bisig, Christiane Copie-bergman, Philippe Gaulard, Maryse Baia, Katty Delbecque, Marie-france Fassotte, Jacques Boniver, Laurence De LevalAbstract:Summary The genetic alterations underlying extranodal marginal zone B-cell lymphomas of Mucosa-Associated Lymphoid Tissue type are heterogeneous and show variation according to the tumor site. Here, we report a case of Mucosa-Associated Lymphoid Tissue lymphoma of the gallbladder with genetic characterization. This lymphoma, diagnosed in a 75-year-old woman who underwent cholecystectomy for suspected acute cholecystitis, presented as diffuse thickening of the gallbladder wall. The morphology was typical of Mucosa-Associated Lymphoid Tissue lymphoma, and by immunophenotype, the tumor cells were CD20+ CD5− CD10− CD23− CD43− BCL6− BCL2+ IgM+ IgD− λ +, with moderate nuclear expression of BCL10. Interphase fluorescence in situ hybridization analysis on paraffin sections, using a fusion probe for API2 / MALT1 , demonstrated 2 fusion signals in most nuclei, bringing the first documentation of a t(11;18)(q21;q21) in this exceptional primary disease location.
Jacques Cadranel - One of the best experts on this subject based on the ideXlab platform.
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Pulmonary Mucosa-Associated Lymphoid Tissue lymphoma revisited
European Respiratory Journal, 2016Co-Authors: Raphael Borie, Catherine Thieblemont, Christiane Copie-bergman, Marie Wislez, Martine Antoine, Jacques CadranelAbstract:This general review sought to clarify the pathophysiological, diagnostic, prognostic, and therapeutic features of pulmonary Mucosa-Associated Lymphoid Tissue (MALT) lymphoma. MALT lymphoma is the most common pulmonary B-cell lymphoma, which usually occurs in the context of acquired MALT. The disease is slow-growing with an asymptomatic chronic alveolar opacity visible on radiography. Diagnosis requires Tissue samples that should be retrieved using minimally invasive techniques, such as bronchoscopy or computed tomography-guided biopsies. The pathophysiology includes cytogenetic abnormalities and autoimmune diseases, whereas an association with a chronic pulmonary infection is still suspected but not yet demonstrated. Disease prognosis is typically excellent and the current available treatments are discussed in this review, including the decision not to treat, surgery, and single- or double-agent chemotherapy.
Gideon Steinbach - One of the best experts on this subject based on the ideXlab platform.
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Antibiotic treatment of gastric lymphoma of Mucosa-Associated Lymphoid Tissue: An uncontrolled trial
Annals of internal medicine, 1999Co-Authors: Gideon Steinbach, Richard J. Ford, Gary Glober, Dory Sample, Frederick B. Hagemeister, Patrick M. Lynch, Peter Mclaughlin, Maria A. Rodriguez, Jorge E. Romaguera, Andreas H. SarrisAbstract:A subset of Helicobacter pylori–positive gastric Mucosa-Associated Lymphoid Tissue lymphomas, including infiltrative tumors, may respond to antibiotic treatment. The likelihood of early complete re...
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Regression of gastric lymphoma of Mucosa-Associated Lymphoid Tissue with antibiotic therapy for Helicobacter pylori
Gastroenterology, 1994Co-Authors: Donna M. Weber, Meletios A. Dimopoulos, Darshan P. Anandu, William C. Pugh, Gideon SteinbachAbstract:Regression of low-grade B cell gastric lymphoma of Mucosa-Associated Lymphoid Tissue after eradication of Helicobacter pylori with antibiotic therapy was recently shown in a small number of patients with low-volume tumors. A patient with a > 10 cm nodular gastric Mucosa-Associated Lymphoid Tissue lymphoma that caused hematemesis and weight loss is described. Antibiotic therapy of H. pylori resulted in full clinical recovery and resolution of the mass lesion and morphological features of lymphoma on routine histological examination. However, monotypic immunostaining of plasma cells persisted in a separate and grossly normal-appearing region of the stomach. Antibiotic therapy may be of benefit in patients with Mucosa-Associated Lymphoid Tissue lymphoma with mass lesions and significant signs and symptoms, but periodic search for residual lymphoma is needed.
Motomi Shiono - One of the best experts on this subject based on the ideXlab platform.
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Thymic and Pulmonary Mucosa-Associated Lymphoid Tissue Lymphomas
The Annals of thoracic surgery, 2013Co-Authors: Takashi Muramatsu, Yoko Tanaka, Ryota Higure, Misato Iizuka, Hiroaki Hata, Motomi ShionoAbstract:A 52-year-old woman with no history of autoimmune disease was found to have a mediastinal tumor and focal airspace opacity in the right lung. Tissue diagnosis was obtained by resection of the mediastinal tumor and open fine needle aspiration of the right pulmonary Tissue through a median sternotomy. Histopathologic examination and immunohistochemistry of the thymus tumor and cytologic analysis of the pulmonary Tissue were both consistent with Mucosa-Associated Lymphoid Tissue (MALT) lymphoma. This case suggests that multiorgan MALT lymphoma can also develop in the absence of an autoimmune disease such as Sjogren's syndrome.