The Experts below are selected from a list of 8526 Experts worldwide ranked by ideXlab platform
Yvonne Bordon - One of the best experts on this subject based on the ideXlab platform.
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Mucosal Immunology neuroendocrine cells regulate lung inflammation
Nature Reviews Immunology, 2016Co-Authors: Yvonne BordonAbstract:A rare population of neuroendocrine cells in the lung epithelium can shape immune responses and tissue remodelling in the lungs.
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Mucosal Immunology a smoke induced microrna fires up dcs
Nature Reviews Immunology, 2015Co-Authors: Yvonne BordonAbstract:Smoking promotes pathogenic TH17 cell responses by inducing the expression of miR-22 in myeloid cells.
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Mucosal Immunology microbiota induced t cells block allergic inflammation
Nature Reviews Immunology, 2015Co-Authors: Yvonne BordonAbstract:The intestinal microbiota restrains type 2 immune responses by inducing the development of RORγt-expressing T cells.
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Mucosal Immunology food additives feed the fire
Nature Reviews Immunology, 2015Co-Authors: Yvonne BordonAbstract:Emulsifying agents found in food may contribute to colitis and metabolic syndrome by disrupting the intestinal microbiota.
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Mucosal Immunology killing time in the lungs
Nature Reviews Immunology, 2014Co-Authors: Yvonne BordonAbstract:Pulmonary epithelial cells drive rhythmic neutrophil recruitment by secreting chemokines in a clock-dependent manner.
Kirsty Minton - One of the best experts on this subject based on the ideXlab platform.
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Mucosal Immunology glucose not good for the gut
Nature Reviews Immunology, 2018Co-Authors: Kirsty MintonAbstract:Hyperglycaemia directly mediates dysfunction of the intestinal epithelial barrier in obesity, leading to increased translocation of microbial products.
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Mucosal Immunology rationing ahr ligands
Nature Reviews Immunology, 2017Co-Authors: Kirsty MintonAbstract:CYP1 enzymes expressed by intestinal epithelial cells metabolise AHR ligands in the gut to regulate intestinal immune responses.
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Mucosal Immunology weaning off food allergy
Nature Reviews Immunology, 2016Co-Authors: Kirsty MintonAbstract:Weaning onto solid food induces regulatory T cell populations in the small intestine that help protect against food allergy.
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Mucosal Immunology sick of the flu
Nature Reviews Immunology, 2014Co-Authors: Kirsty MintonAbstract:Respiratory infection with influenza virus causes intestinal symptoms through the specific recruitment of lung-induced CD4+ T cells to the intestinal mucosa.
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Mucosal Immunology a safety catch to prevent intestinal inflammation
Nature Reviews Immunology, 2012Co-Authors: Kirsty MintonAbstract:Intestinal dendritic cells make the requirements for TH17 cell induction in the gut more stringent than in systemic tissues.
J M Bernstein - One of the best experts on this subject based on the ideXlab platform.
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Mucosal Immunology of the upper respiratory tract.
Respiration; international review of thoracic diseases, 1992Co-Authors: J M BernsteinAbstract:The palatine tonsils and nasopharyngeal adenoids represent the predominant immunocompetent tissue of the upper respiratory tract. Its major function is as a first line of defense against viral, bacterial, and food antigens that enter the upper aerodigestive system. Another major function of the tonsils and adenoids is to supply the local Mucosal immune system of the upper respiratory tract with dimeric IgA-producing B cells. Secretory IgA has particular hydrophilic properties and is capable of preventing adsorption and penetration of bacteria and/or viruses into the upper respiratory tract mucosa. In addition, the role of the indigenous flora of the upper respiratory tract, particularly the viridans streptococci has been emphasized as providing a valuable source of bacterial interference to the colonization of potential pathogens.
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Mucosal Immunology of the upper respiratory tract
Respiration, 1992Co-Authors: J M BernsteinAbstract:The palatine tonsils and nasopharyngeal adenoids represent the predominant immunocompetent tissue of the upper respiratory tract. Its major function is as a first line of defense against viral, bacter
Guido Ferlazzo - One of the best experts on this subject based on the ideXlab platform.
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Mucosal Immunology and probiotics
Current Allergy and Asthma Reports, 2013Co-Authors: Maria Luisa Dongarra, Valeria Rizzello, Letizia Muccio, Walter Fries, Antonio Cascio, Irene Bonaccorsi, Guido FerlazzoAbstract:The cross-talk between the mucosa-associated immune system and microbiota is critical in Mucosal tissue homeostasis as well as in protection against infectious and inflammatory diseases occurring at Mucosal sites. This recent evidence has paved the way to therapeutic approaches aimed at modulating the mucosa-associated immune system using probiotics. Different strains of probiotics possess the ability to finely regulate dendritic cell (DC) activation, polarizing the subsequent T cell activity toward Th1 (e.g. Lactobacillus (Lb) acidophilus), Th2 (Lb.reuteri and Bifidobacterium bifidum) or, as more recently demonstrated, Th17 responses induced by specific strains such as Lb.rhamnosus GG and Lac23a, the latter isolated in our laboratory. Here, we review some recent advances in our understanding of probiotics effects on Mucosal Immunology, particularly on cells of the innate immunity such as DCs. We also highlight our own experiences in modulating DC functions by commensal bacteria and discuss the relevance of probiotics administration in the treatment of human immunopathologies.
Allan W Cripps - One of the best experts on this subject based on the ideXlab platform.
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middle ear and eustachian tube Mucosal Immunology
Mucosal Immunology (Fourth Edition), 2015Co-Authors: Helen Maureen Massa, Yuichi Kurono, Allan W CrippsAbstract:Mucosal immune responses within the middle ear and eustachian tube generally provide an effective and efficient response to the presence of microbial pathogens, with approximately 80% of clinically recognizable middle ear infections resolved within 7 days. Particularly for young children aged less than 3 years of age, the proximity and direct connection of the middle ear, via the eustachian tube, to the nasopharynx provide increased risk of commensal bacteria and upper respiratory tract viruses infecting the middle ear. Mucosal immunological defense in the middle ear and eustachian tube utilizes a number of mechanisms, including physicochemical barriers of mucus and the Mucosal epithelial cells and innate immune responses such as inflammation, cellular infiltration, effusion, and antimicrobial protein secretions, in addition to adaptive host immune responses. Recent advances in otopathogen recognition via microbial pattern recognition receptors and elucidation of complex signaling cascades have improved understanding of the coordination and regulation of the middle ear Mucosal response. These advances support vaccine development aiming to reduce the risk of otitis media in children.
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Mucosal Immunology down under special interest group in Mucosal Immunology workshop australasian society for Immunology sydney australia 2 december 2007
Immunology and Cell Biology, 2008Co-Authors: Allan W Cripps, Philip Sutton, Kenneth W Beagley, Sarah A Robertson, M L DunkleyAbstract:The Mucosal Immunology Special Interest Group (SIG-MI) of the Australasian Society of Immunology was formed 14 years ago and has run regular symposia and workshops in conjunction with the Australasian Society of Immunology since that time. In December 2007 the Mucosal Immunology Special Interest Group held a 1-day satellite workshop in conjunction with the annual Australasian Society of Immunology scientific meeting in Sydney to celebrate the decade since hosting the 9th International Congress of Mucosal Immunology (9-ICMI) in 1997, which was also held in Sydney. The meeting that was attended by 65 delegates focussed on 4 session themes: reproductive Immunology, respiratory Immunology, Mucosal Immunology of the gastrointestinal tract and Mucosal vaccines.
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acute on chronic bronchitis a model of Mucosal Immunology
Immunology and Cell Biology, 1995Co-Authors: Robert Clancy, M L Dunkley, Gerald Pang, Diana C Taylor, Allan W CrippsAbstract:: Acute bronchitis has been studied as a model of disturbed Mucosal immunoregulation. A new hypothesis relating to the pathogenesis of acute bronchitis has been developed, based on altered host response as the prime mover. Infection-prone subjects had low levels of lysozyme. Effective oral immunization, especially if early, reduced levels of bacterial colonization. Future attention focuses on intra bronchial inflammation and its link to the host-parasite relationship.
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Ontogeny of the Mucosal immune response in children.
Advances in Experimental Medicine and Biology, 1991Co-Authors: Allan W Cripps, Maree Gleeson, Robert ClancyAbstract:The theory of Mucosal Immunology is now well advanced and supported by experimental data. It is clear that Mucosal immune responses can be manipulated and that individuals who can be defined as having a deficit in Mucosal immune competence appear to be prone to chronic conditions such as recurrent infection, atopy and clinical asthma.