The Experts below are selected from a list of 2778 Experts worldwide ranked by ideXlab platform
Marion J Skalweit - One of the best experts on this subject based on the ideXlab platform.
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ibrutinib therapy and Mycobacterium chelonae skin and soft tissue infection
Open Forum Infectious Diseases, 2018Co-Authors: Khalid M Dousa, Ahmed Babiker, Daniel Van Aartsen, Neel Shah, Robert A Bonomo, John L Johnson, Marion J SkalweitAbstract:: Ibrutinib is an irreversible inhibitor of Bruton's tyrosine kinase approved for the treatment of B-cell malignancies. There is growing concern about the risk of opportunistic infections following ibrutinib therapy. Herein, we describe the first case of Mycobacterium chelonae skin and soft tissue infection in a patient receiving ibrutinib and recount the challenges in treating this infection.
Michael C. Bach - One of the best experts on this subject based on the ideXlab platform.
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A pseudo-outbreak of Mycobacterium chelonae infections related to bronchoscopy.
Infection control and hospital epidemiology, 1997Co-Authors: Ronald Cox, Karen Deborja, Michael C. BachAbstract:Mycobacterium gordonae and rapidly growing "atypical" mycobacteria including Mycobacterium chelonae are commonly found in tap water. This article describes a pseudo-outbreak of M chelonae infections related to bronchoscopy. Because patients may be treated and isolated unnecessarily when positive with acid-fast bacilli before the species are known, the financial burden for patients and hospitals may be great.
Yoon Hoh Kook - One of the best experts on this subject based on the ideXlab platform.
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Description of Mycobacterium chelonae subsp. bovis subsp. nov., isolated from cattle (Bos taurus coreanae), emended description of Mycobacterium chelonae and creation of Mycobacterium chelonae subsp. chelonae subsp. nov.
International journal of systematic and evolutionary microbiology, 2017Co-Authors: Byoung Jun Kim, Ga Na Kim, Boram Kim, Che Ok Jeon, Joseph Jeong, Seon Ho Lee, Ji Hun Lim, Seung Heon Lee, Chang Ki Kim, Yoon Hoh KookAbstract:Three rapidly growing mycobacterial strains, QIA-37T, QIA-40 and QIA-41, were isolated from the lymph nodes of three separate Korean native cattle, Hanwoo (Bos taurus coreanae). These strains were previously shown to be phylogenetically distinct but closely related to Mycobacterium chelonae ATCC 35752T by taxonomic approaches targeting three genes (16S rRNA, hsp6 and rpoB) and were further characterized using a polyphasic approach in this study. The 16S rRNA gene sequences of all three strains showed 99.7 % sequence similarity with that of the M. chelonae type strain. A multilocus sequence typing analysis targeting 10 housekeeping genes, including hsp65 and rpoB, revealed a phylogenetic cluster of these strains with M. chelonae . DNA–DNA hybridization values of 78.2 % between QIA-37T and M. chelonae indicated that it belongs to M. chelonae but is a novel subspecies distinct from M. chelonae . Phylogenetic analysis based on whole-genome sequences revealed a 95.44±0.06 % average nucleotide identity (ANI) value with M. chelonae , slightly higher than the 95.0 % ANI criterion for determining a novel species. In addition, distinct phenotypic characteristics such as positive growth at 37 °C, at which temperature M. chelonae does not grow, further support the taxonomic status of these strains as representatives of a novel subspecies of M. chelonae . Therefore, we propose an emended description of Mycobacterium chelonae , and descriptions of M. chelonae subsp. chelonae subsp. nov. and M. chelonae subsp. bovis subsp. nov. are presented; strains ATCC 35752T(=CCUG 47445T=CIP 104535T=DSM 43804T=JCM 6388T=NCTC 946T) and QIA-37T (=KCTC 39630T=JCM 30986T) are the type strains of the two novel subspecies.
Donald E. Craven - One of the best experts on this subject based on the ideXlab platform.
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Molecular typing of Mycobacterium chelonae isolates from a pseudo-outbreak involving an automated bronchoscope washer.
Infection control and hospital epidemiology, 2008Co-Authors: Alexandra Chroneou, Sarah K. Zimmerman, Steven Cook, Sandra Willey, Jane Eyre-kelly, Nikolaos Zias, Daniel S. Shapiro, John F. Beamis, Donald E. CravenAbstract:We describe a pseudo-outbreak of Mycobacterium chelonae infection in bronchoalveolar lavage fluid from 9 patients that was traced to contamination of an automated bronchoscope washer. Molecular typing using repetitive extragenic palindromic polymerase chain reaction was helpful in confirming epidemiologic and clinical findings.
Khalid M Dousa - One of the best experts on this subject based on the ideXlab platform.
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ibrutinib therapy and Mycobacterium chelonae skin and soft tissue infection
Open Forum Infectious Diseases, 2018Co-Authors: Khalid M Dousa, Ahmed Babiker, Daniel Van Aartsen, Neel Shah, Robert A Bonomo, John L Johnson, Marion J SkalweitAbstract:: Ibrutinib is an irreversible inhibitor of Bruton's tyrosine kinase approved for the treatment of B-cell malignancies. There is growing concern about the risk of opportunistic infections following ibrutinib therapy. Herein, we describe the first case of Mycobacterium chelonae skin and soft tissue infection in a patient receiving ibrutinib and recount the challenges in treating this infection.
