The Experts below are selected from a list of 306 Experts worldwide ranked by ideXlab platform
E. D. Janzen - One of the best experts on this subject based on the ideXlab platform.
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Mycoplasma bovis infections in cattle
Journal of veterinary internal medicine, 2011Co-Authors: Fiona P. Maunsell, Amelia R. Woolums, David Francoz, R. F. Rosenbusch, Douglas L. Step, David J. Wilson, E. D. JanzenAbstract:Mycoplasma bovis is a pathogen causing respiratory disease, otitis media, arthritis, mastitis, and a variety of other diseases in cattle worldwide. It is increasingly recognized by the veterinary and livestock communities as having an important impact on the health, welfare, and productivity of dairy and beef cattle. M. bovis diseases can be difficult to diagnose and control because of inconsistent disease expression and response to treatments and vaccines, and large gaps in our understanding of the epidemiology and pathophysiology of these diseases. There are limited data on which to base evidence-based decisions for treatment and control, and the literature contains differing clinical biases and opinions. This document is intended for veterinarians dealing with cattle and is focused on the cattle production systems of North America. The goal of the consensus statement panel was to encourage an evidence-based approach to M. bovis problems. The scientific literature was critically reviewed, including peer-reviewed journal articles and reviews obtained by database searches using the terms “Mycoplasma bovis” or “Mycoplasma + cattle.” Where other data were lacking, conference proceedings were reviewed as a source of expert opinion.
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The immunohistochemical detection of Mycoplasma bovis and bovine viral diarrhea virus in tissues of feedlot cattle with chronic, unresponsive respiratory disease and/or arthritis.
The Canadian veterinary journal = La revue veterinaire canadienne, 2001Co-Authors: Deborah M. Haines, Karen Martin, Edward G. Clark, G K Jim, E. D. JanzenAbstract:The purpose of this study was to determine the frequency of selected pathogens in the tissues of a group of feedlot cattle with chronic disease (most often respiratory disease and/or arthritis). Samples of lung and joint tissues from 49 feedlot animals that had failed to respond to antibiotic therapy were tested by immunohistochemical staining for the antigens of Mycoplasma bovis, Haemophilus somnus, Pasteurella (Mannheimia) hemolytica, and bovine viral diarrhea virus (BVDV). Mycoplasma bovis was demonstrated in over 80% of cases, including in 45% of joints and 71% of lungs tested. Mycoplasma bovis was the only bacterial pathogen identified in the joints. Haemophilus somnus and Pasteurella (Mannheimia) haemolytica were found in 14% and 23% of cases, respectively, and were confined to the lungs in all instances. Infection with BVDV was demonstrated in over 40% of cases. Mycoplasma bovis and BVDV were the most common pathogens persisting in the tissues of these animals that had failed to respond to antibiotic therapy.
Jeff L Caswell - One of the best experts on this subject based on the ideXlab platform.
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Mycoplasma bovis in respiratory disease of feedlot cattle
Veterinary Clinics of North America-food Animal Practice, 2010Co-Authors: Jeff L Caswell, K G Bateman, Hugh Y Cai, F CastilloalcalaAbstract:Mycoplasma bovis has recently emerged as an important cause of chronic caseonecrotic bronchopneumonia, arthritis, and tenosynovitis in beef cattle. Mycoplasma bovis can act as a primary pathogen, yet many cases are coinfected with other bacteria or viruses, and evidence suggests that M. bovis colonizes and perpetuates lung lesions that were initiated by other bacteria, such as M. haemolytica. Mycoplasma bovis elicits a robust humoral immune response, but the resulting antibodies are not protective because of the variable surface proteins, and vaccines have not yet been shown to prevent disease. Mycoplasma bovis infections are responsible for a high proportion of the chronic disease occurring in feedlots, and the welfare of such animals is an important aspect of feedlot health management.
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Mycoplasma bovis pneumonia in cattle.
Animal health research reviews, 2007Co-Authors: Jeff L Caswell, Marie ArchambaultAbstract:Mycoplasma bovis is an important and emerging cause of respiratory disease and arthritis in feedlot cattle and young dairy and veal calves, and has a variety of other disease manifestations in cattle. M. bovis is certainly capable of causing acute respiratory disease in cattle, yet the attributable fraction has been difficult to estimate. In contrast, M. bovis is more accepted as a cause of chronic bronchopneumonia with caseous and perhaps coagulative necrosis, characterized by persistent infection that seems poorly responsive to many antibiotics. An understanding of the disease has been recently advanced by comparisons of natural and experimentally induced disease, development of molecular diagnostic tools, and understanding some aspects of virulence, yet uncertainties regarding protective immunity, the importance of genotypic diversity, mechanisms of virulence, and the role of co-pathogens have restricted our understanding of pathogenesis and our ability to effectively control the disease. This review critically considers the relationship between M. bovis infection and the various manifestations of the bovine respiratory disease complex, and addresses the pathogenesis, clinical and pathologic sequelae, laboratory diagnosis and control of disease resulting from M. bovis infection in the bovine respiratory tract.
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naturally occurring Mycoplasma bovis associated pneumonia and polyarthritis in feedlot beef calves
Journal of Veterinary Diagnostic Investigation, 2006Co-Authors: Mihai I Gagea, K G Bateman, Marie Archambault, Rachel A Shanahan, Tony Van Dreumel, Beverly Mcewen, Susy Carman, Jeff L CaswellAbstract:Mycoplasma bovis is perceived as an emerging cause of mortality in feedlot beef cattle. This study examined the lesions and infectious agents in naturally occurring M. bovis-associated bronchopneumonia and arthritis and the relationship of this condition with bovine viral diarrhea virus (BVDV) infection. Standardized pathologic, immunohistochemical, and microbiologic investigations were conducted on 99 calves that died or were euthanized within 60 days after arrival in 72 feedlots. Cranioventral bronchopneumonia with multiple foci of caseous necrosis was identified in 54 of 99 calves, including 30 with concurrent fibrinosuppurative bronchopneumonia typical of pneumonic pasteurellosis. Mycoplasma bovis was consistently identified in these lesions by culture and immunohistochemistry, but also commonly in healthy lungs and those with pneumonia of other causes. Focal lesions of coagulation necrosis, typical of pneumonic pasteurellosis, were often infected with both Mannheimia haemolytica and M. bovis. Arthritis was present in 25 of 54 (46%) calves with M. bovis pneumonia, and all calves with arthritis had pneumonia. BVDV infection was more common in calves with lesions of bacterial pneumonia than in those dying of other causes, but BVDV infection was not more common in calves with caseonecrotic bronchopneumonia than those with fibrinosuppurative bronchopneumonia. Retrospective analysis identified cases of M. bovis pneumonia in the early 1980s that had milder lesions than the current cases. The findings suggest that, in at least some calves, M. bovis induces caseonecrotic bronchopneumonia within the lesions of pneumonic pasteurellosis.
Karl-erik Johansson - One of the best experts on this subject based on the ideXlab platform.
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The phylogeny of Mycoplasma bovis as determined by sequence analysis of the 16S rRNA gene
FEMS microbiology letters, 1994Co-Authors: Jens G. Mattsson, Bengt Guss, Karl-erik JohanssonAbstract:The nucleotide sequence of the 16S rRNA gene of Mycoplasma bovis has been determined. Comparisons with other 16S rRNA sequences of Mycoplasmas showed that Mycoplasma agalactiae is phylogenetically the closet relative. In total, only eight nucleotides differed between the M. bovis and M. agalactiae 16S rRNA sequences. The phylogenetic position of M. bovis with respect to other Mycoplasmas was determined by sequence comparisons and from features in the secondary structure of 16S rRNA.
F Castilloalcala - One of the best experts on this subject based on the ideXlab platform.
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Mycoplasma bovis in respiratory disease of feedlot cattle
Veterinary Clinics of North America-food Animal Practice, 2010Co-Authors: Jeff L Caswell, K G Bateman, Hugh Y Cai, F CastilloalcalaAbstract:Mycoplasma bovis has recently emerged as an important cause of chronic caseonecrotic bronchopneumonia, arthritis, and tenosynovitis in beef cattle. Mycoplasma bovis can act as a primary pathogen, yet many cases are coinfected with other bacteria or viruses, and evidence suggests that M. bovis colonizes and perpetuates lung lesions that were initiated by other bacteria, such as M. haemolytica. Mycoplasma bovis elicits a robust humoral immune response, but the resulting antibodies are not protective because of the variable surface proteins, and vaccines have not yet been shown to prevent disease. Mycoplasma bovis infections are responsible for a high proportion of the chronic disease occurring in feedlots, and the welfare of such animals is an important aspect of feedlot health management.
Paola Pilo - One of the best experts on this subject based on the ideXlab platform.
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Virulence, persistence and dissemination of Mycoplasma bovis.
Veterinary microbiology, 2015Co-Authors: Sibylle Bürki, Joachim Frey, Paola PiloAbstract:Bovine mycoplasmosis due to Mycoplasma bovis causes several important bovine diseases such as pneumonia, mastitis, arthritis, otitis, genital disorders or keratoconjunctivitis. Variable surface lipoproteins, adhesion, invasion of host cells, modulation of the host immune system, biofilm formation and the release of secondary metabolites like hydrogen peroxide, as well as synergistic infections with other bacterial or viral pathogens are among the more significantly studied characteristics of the bacterium. The aim of this review is to summarize the current knowledge regarding the virulence of M. bovis and additionally, factors contributing to the dissemination and persistence of this pathogen in the bovine host will be discussed.
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Direct detection of Mycoplasma bovis in milk and tissue samples by real-time PCR.
Molecular and cellular probes, 2010Co-Authors: Bigna C. Rossetti, Joachim Frey, Paola PiloAbstract:Bovine mastitis caused by Mycoplasma bovis is of great economic importance to the beef and dairy industry. Here we describe a new specific real-time PCR assay targeting the uvrC gene that was developed to directly detect M. bovis from milk and tissue samples without laborious DNA purification.
