The Experts below are selected from a list of 2025 Experts worldwide ranked by ideXlab platform
Enoch Y. Park - One of the best experts on this subject based on the ideXlab platform.
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localized surface plasmon resonance mediated fluorescence signals in plasmonic Nanoparticle Quantum Dot hybrids for ultrasensitive zika virus rna detection via hairpin hybridization assays
Biosensors and Bioelectronics, 2017Co-Authors: Oluwasesan Adegoke, Masahiro Morita, Tatsuya Kato, Tetsuro Suzuki, Masahito Ito, Enoch Y. ParkAbstract:The current epidemic caused by the Zika virus (ZIKV) and the devastating effects of this virus on fetal development, which result in an increased incidence of congenital microcephaly symptoms, have prompted the World Health Organization (WHO) to declare the ZIKV a public health issue of global concern. Efficient probes that offer high detection sensitivity and specificity are urgently required to aid in the point-of-care treatment of the virus. In this study, we show that localized surface plasmon resonance (LSPR) signals from plasmonic Nanoparticles (NPs) can be used to mediate the fluorescence signal from semiconductor Quantum Dot (QDot) nanocrystals in a molecular beacon (MB) biosensor probe for ZIKV RNA detection. Four different plasmonic NPs functionalized with 3-mercaptopropionic acid (MPA), namely MPA-AgNPs, MPA-AuNPs, core/shell (CS) Au/AgNPs, and alloyed AuAgNPs, were synthesized and conjugated to L-glutathione-capped CdSeS alloyed QDots to form the respective LSPR-mediated fluorescence nanohybrid. The concept of the plasmonic NP-QDot-MB biosensor involves using LSPR from the plasmonic NPs to mediate a fluorescence signal to the QDots, triggered by the hybridization of the target ZIKV RNA with the DNA loop sequence of the MB. The extent of the fluorescence enhancement based on ZIKV RNA detection was proportional to the LSPR-mediated fluorescence signal. The limits of detection (LODs) of the nanohybrids were as follows: alloyed AuAgNP-QDot646-MB (1.7 copies/mL)) > CS Au/AgNP-QDot646-MB (LOD =2.4 copies/mL) > AuNP-QDot646-MB (LOD =2.9 copies/mL) > AgNP-QDot646-MB (LOD =7.6 copies/mL). The LSPR-mediated fluorescence signal was stronger for the bimetallic plasmonic NP-QDots than the single metallic plasmonic NP-QDots. The plasmonic NP-QDot-MB biosensor probes exhibited excellent selectivity toward ZIKV RNA and could serve as potential diagnostic probes for the point-of care detection of the virus.
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localized surface plasmon resonance mediated fluorescence signals in plasmonic Nanoparticle Quantum Dot hybrids for ultrasensitive zika virus rna detection via hairpin hybridization assays
Biosensors and Bioelectronics, 2017Co-Authors: Oluwasesan Adegoke, Masahiro Morita, Tatsuya Kato, Tetsuro Suzuki, Enoch Y. ParkAbstract:The current epidemic caused by the Zika virus (ZIKV) and the devastating effects of this virus on fetal development, which result in an increased incidence of congenital microcephaly symptoms, have prompted the World Health Organization (WHO) to declare the ZIKV a public health issue of global concern. Efficient probes that offer high detection sensitivity and specificity are urgently required to aid in the point-of-care treatment of the virus. In this study, we show that localized surface plasmon resonance (LSPR) signals from plasmonic Nanoparticles (NPs) can be used to mediate the fluorescence signal from semiconductor Quantum Dot (QDot) nanocrystals in a molecular beacon (MB) biosensor probe for ZIKV RNA detection. Four different plasmonic NPs functionalized with 3-mercaptopropionic acid (MPA), namely MPA-AgNPs, MPA-AuNPs, core/shell (CS) Au/AgNPs, and alloyed AuAgNPs, were synthesized and conjugated to L-glutathione-capped CdSeS alloyed QDots to form the respective LSPR-mediated fluorescence nanohybrid. The concept of the plasmonic NP-QDot-MB biosensor involves using LSPR from the plasmonic NPs to mediate a fluorescence signal to the QDots, triggered by the hybridization of the target ZIKV RNA with the DNA loop sequence of the MB. The extent of the fluorescence enhancement based on ZIKV RNA detection was proportional to the LSPR-mediated fluorescence signal. The limits of detection (LODs) of the nanohybrids were as follows: alloyed AuAgNP-QDot646-MB (1.7 copies/mL)) > CS Au/AgNP-QDot646-MB (LOD =2.4 copies/mL) > AuNP-QDot646-MB (LOD =2.9 copies/mL) > AgNP-QDot646-MB (LOD =7.6 copies/mL). The LSPR-mediated fluorescence signal was stronger for the bimetallic plasmonic NP-QDots than the single metallic plasmonic NP-QDots. The plasmonic NP-QDot-MB biosensor probes exhibited excellent selectivity toward ZIKV RNA and could serve as potential diagnostic probes for the point-of care detection of the virus.
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Gold Nanoparticle-Quantum Dot Fluorescent Nanohybrid: Application for Localized Surface Plasmon Resonance-induced Molecular Beacon Ultrasensitive DNA Detection
Nanoscale Research Letters, 2016Co-Authors: Oluwasesan Adegoke, Enoch Y. ParkAbstract:In biosensor design, localized surface plasmon resonance (LSPR)-induced signal from gold Nanoparticle (AuNP)-conjugated reporter can produce highly sensitive nanohybrid systems. In order to retain the physicochemical properties of AuNPs upon conjugation, high colloidal stability in aqueous solution is needed. In this work, the colloidal stability with respect to the zeta potential (ZP) of four negatively charged thiol-functionalized AuNPs, thioglycolic (TGA)-AuNPs, 3-mercaptopropionic acid (MPA)-AuNPs, l -cysteine-AuNPs and l -glutathione (GSH)-AuNPs, and a cationic cyteamine-capped AuNPs was studied at various pHs, ionic strength, and NP concentration. A strong dependence of the ZP charge on the Nanoparticle (NP) concentration was observed. High colloidal stability was exhibited between pH 3 and 9 for the negatively charged AuNPs and between pH 3 and 7 for the cationic AuNPs. With respect to the ionic strength, high colloidal stability was exhibited at ≤10^4 μM for TGA-AuNPs, l -cysteine-AuNPs, and GSH-AuNPs, whereas ≤10^3 μM is recommended for MPA-AuNPs. For the cationic AuNPs, very low ionic strength of ≤10 μM is recommended due to deprotonation at higher concentration. GSH-AuNPs were thereafter bonded to SiO_2-functionalized alloyed CdZnSeS/ZnSe_1.0S_1.3 Quantum Dots (SiO_2-QDots) to form a plasmon-enhanced AuNP-SiO_2-QDots fluorescent nanohybrid. The AuNP-SiO_2-QDots conjugate was afterward conjugated to a molecular beacon (MB), thus forming an ultrasensitive LSPR-induced SiO_2-QDots-MB biosensor probe that detected a perfect nucleotide DNA sequence at a concentration as low as 10 fg/mL. The limit of detection was ~11 fg/mL (1.4 fM) while the biosensor probe efficiently distinguished between single-base mismatch and noncomplementary sequence target.
Oluwasesan Adegoke - One of the best experts on this subject based on the ideXlab platform.
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localized surface plasmon resonance mediated fluorescence signals in plasmonic Nanoparticle Quantum Dot hybrids for ultrasensitive zika virus rna detection via hairpin hybridization assays
Biosensors and Bioelectronics, 2017Co-Authors: Oluwasesan Adegoke, Masahiro Morita, Tatsuya Kato, Tetsuro Suzuki, Masahito Ito, Enoch Y. ParkAbstract:The current epidemic caused by the Zika virus (ZIKV) and the devastating effects of this virus on fetal development, which result in an increased incidence of congenital microcephaly symptoms, have prompted the World Health Organization (WHO) to declare the ZIKV a public health issue of global concern. Efficient probes that offer high detection sensitivity and specificity are urgently required to aid in the point-of-care treatment of the virus. In this study, we show that localized surface plasmon resonance (LSPR) signals from plasmonic Nanoparticles (NPs) can be used to mediate the fluorescence signal from semiconductor Quantum Dot (QDot) nanocrystals in a molecular beacon (MB) biosensor probe for ZIKV RNA detection. Four different plasmonic NPs functionalized with 3-mercaptopropionic acid (MPA), namely MPA-AgNPs, MPA-AuNPs, core/shell (CS) Au/AgNPs, and alloyed AuAgNPs, were synthesized and conjugated to L-glutathione-capped CdSeS alloyed QDots to form the respective LSPR-mediated fluorescence nanohybrid. The concept of the plasmonic NP-QDot-MB biosensor involves using LSPR from the plasmonic NPs to mediate a fluorescence signal to the QDots, triggered by the hybridization of the target ZIKV RNA with the DNA loop sequence of the MB. The extent of the fluorescence enhancement based on ZIKV RNA detection was proportional to the LSPR-mediated fluorescence signal. The limits of detection (LODs) of the nanohybrids were as follows: alloyed AuAgNP-QDot646-MB (1.7 copies/mL)) > CS Au/AgNP-QDot646-MB (LOD =2.4 copies/mL) > AuNP-QDot646-MB (LOD =2.9 copies/mL) > AgNP-QDot646-MB (LOD =7.6 copies/mL). The LSPR-mediated fluorescence signal was stronger for the bimetallic plasmonic NP-QDots than the single metallic plasmonic NP-QDots. The plasmonic NP-QDot-MB biosensor probes exhibited excellent selectivity toward ZIKV RNA and could serve as potential diagnostic probes for the point-of care detection of the virus.
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localized surface plasmon resonance mediated fluorescence signals in plasmonic Nanoparticle Quantum Dot hybrids for ultrasensitive zika virus rna detection via hairpin hybridization assays
Biosensors and Bioelectronics, 2017Co-Authors: Oluwasesan Adegoke, Masahiro Morita, Tatsuya Kato, Tetsuro Suzuki, Enoch Y. ParkAbstract:The current epidemic caused by the Zika virus (ZIKV) and the devastating effects of this virus on fetal development, which result in an increased incidence of congenital microcephaly symptoms, have prompted the World Health Organization (WHO) to declare the ZIKV a public health issue of global concern. Efficient probes that offer high detection sensitivity and specificity are urgently required to aid in the point-of-care treatment of the virus. In this study, we show that localized surface plasmon resonance (LSPR) signals from plasmonic Nanoparticles (NPs) can be used to mediate the fluorescence signal from semiconductor Quantum Dot (QDot) nanocrystals in a molecular beacon (MB) biosensor probe for ZIKV RNA detection. Four different plasmonic NPs functionalized with 3-mercaptopropionic acid (MPA), namely MPA-AgNPs, MPA-AuNPs, core/shell (CS) Au/AgNPs, and alloyed AuAgNPs, were synthesized and conjugated to L-glutathione-capped CdSeS alloyed QDots to form the respective LSPR-mediated fluorescence nanohybrid. The concept of the plasmonic NP-QDot-MB biosensor involves using LSPR from the plasmonic NPs to mediate a fluorescence signal to the QDots, triggered by the hybridization of the target ZIKV RNA with the DNA loop sequence of the MB. The extent of the fluorescence enhancement based on ZIKV RNA detection was proportional to the LSPR-mediated fluorescence signal. The limits of detection (LODs) of the nanohybrids were as follows: alloyed AuAgNP-QDot646-MB (1.7 copies/mL)) > CS Au/AgNP-QDot646-MB (LOD =2.4 copies/mL) > AuNP-QDot646-MB (LOD =2.9 copies/mL) > AgNP-QDot646-MB (LOD =7.6 copies/mL). The LSPR-mediated fluorescence signal was stronger for the bimetallic plasmonic NP-QDots than the single metallic plasmonic NP-QDots. The plasmonic NP-QDot-MB biosensor probes exhibited excellent selectivity toward ZIKV RNA and could serve as potential diagnostic probes for the point-of care detection of the virus.
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Gold Nanoparticle-Quantum Dot Fluorescent Nanohybrid: Application for Localized Surface Plasmon Resonance-induced Molecular Beacon Ultrasensitive DNA Detection
Nanoscale Research Letters, 2016Co-Authors: Oluwasesan Adegoke, Enoch Y. ParkAbstract:In biosensor design, localized surface plasmon resonance (LSPR)-induced signal from gold Nanoparticle (AuNP)-conjugated reporter can produce highly sensitive nanohybrid systems. In order to retain the physicochemical properties of AuNPs upon conjugation, high colloidal stability in aqueous solution is needed. In this work, the colloidal stability with respect to the zeta potential (ZP) of four negatively charged thiol-functionalized AuNPs, thioglycolic (TGA)-AuNPs, 3-mercaptopropionic acid (MPA)-AuNPs, l -cysteine-AuNPs and l -glutathione (GSH)-AuNPs, and a cationic cyteamine-capped AuNPs was studied at various pHs, ionic strength, and NP concentration. A strong dependence of the ZP charge on the Nanoparticle (NP) concentration was observed. High colloidal stability was exhibited between pH 3 and 9 for the negatively charged AuNPs and between pH 3 and 7 for the cationic AuNPs. With respect to the ionic strength, high colloidal stability was exhibited at ≤10^4 μM for TGA-AuNPs, l -cysteine-AuNPs, and GSH-AuNPs, whereas ≤10^3 μM is recommended for MPA-AuNPs. For the cationic AuNPs, very low ionic strength of ≤10 μM is recommended due to deprotonation at higher concentration. GSH-AuNPs were thereafter bonded to SiO_2-functionalized alloyed CdZnSeS/ZnSe_1.0S_1.3 Quantum Dots (SiO_2-QDots) to form a plasmon-enhanced AuNP-SiO_2-QDots fluorescent nanohybrid. The AuNP-SiO_2-QDots conjugate was afterward conjugated to a molecular beacon (MB), thus forming an ultrasensitive LSPR-induced SiO_2-QDots-MB biosensor probe that detected a perfect nucleotide DNA sequence at a concentration as low as 10 fg/mL. The limit of detection was ~11 fg/mL (1.4 fM) while the biosensor probe efficiently distinguished between single-base mismatch and noncomplementary sequence target.
Nannan Guo - One of the best experts on this subject based on the ideXlab platform.
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dna templated magnetic Nanoparticle Quantum Dot polymers for ultrasensitive capture and detection of circulating tumor cells
Advanced Functional Materials, 2018Co-Authors: Ganglin Wang, Yi Shen, Nannan GuoAbstract:DNA‐templated magnetic Nanoparticle‐Quantum Dot‐aptamer copolymers (MQAPs) are constructed through a hybridization chain reaction for rapid enumeration and identification of circulating tumor cells with high capture efficiency and capture purity approaching 80%. These MQAPs exhibit amplified magnetic response, extraordinary binding selectivity for target cells over background cells, and ultra bright ensemble Quantum Dot photoluminescence for single cell detection.
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DNA‐Templated Magnetic Nanoparticle‐Quantum Dot Polymers for Ultrasensitive Capture and Detection of Circulating Tumor Cells
Advanced Functional Materials, 2018Co-Authors: Ganglin Wang, Yi Shen, Nannan GuoAbstract:DNA‐templated magnetic Nanoparticle‐Quantum Dot‐aptamer copolymers (MQAPs) are constructed through a hybridization chain reaction for rapid enumeration and identification of circulating tumor cells with high capture efficiency and capture purity approaching 80%. These MQAPs exhibit amplified magnetic response, extraordinary binding selectivity for target cells over background cells, and ultra bright ensemble Quantum Dot photoluminescence for single cell detection.
Tetsuro Suzuki - One of the best experts on this subject based on the ideXlab platform.
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localized surface plasmon resonance mediated fluorescence signals in plasmonic Nanoparticle Quantum Dot hybrids for ultrasensitive zika virus rna detection via hairpin hybridization assays
Biosensors and Bioelectronics, 2017Co-Authors: Oluwasesan Adegoke, Masahiro Morita, Tatsuya Kato, Tetsuro Suzuki, Enoch Y. ParkAbstract:The current epidemic caused by the Zika virus (ZIKV) and the devastating effects of this virus on fetal development, which result in an increased incidence of congenital microcephaly symptoms, have prompted the World Health Organization (WHO) to declare the ZIKV a public health issue of global concern. Efficient probes that offer high detection sensitivity and specificity are urgently required to aid in the point-of-care treatment of the virus. In this study, we show that localized surface plasmon resonance (LSPR) signals from plasmonic Nanoparticles (NPs) can be used to mediate the fluorescence signal from semiconductor Quantum Dot (QDot) nanocrystals in a molecular beacon (MB) biosensor probe for ZIKV RNA detection. Four different plasmonic NPs functionalized with 3-mercaptopropionic acid (MPA), namely MPA-AgNPs, MPA-AuNPs, core/shell (CS) Au/AgNPs, and alloyed AuAgNPs, were synthesized and conjugated to L-glutathione-capped CdSeS alloyed QDots to form the respective LSPR-mediated fluorescence nanohybrid. The concept of the plasmonic NP-QDot-MB biosensor involves using LSPR from the plasmonic NPs to mediate a fluorescence signal to the QDots, triggered by the hybridization of the target ZIKV RNA with the DNA loop sequence of the MB. The extent of the fluorescence enhancement based on ZIKV RNA detection was proportional to the LSPR-mediated fluorescence signal. The limits of detection (LODs) of the nanohybrids were as follows: alloyed AuAgNP-QDot646-MB (1.7 copies/mL)) > CS Au/AgNP-QDot646-MB (LOD =2.4 copies/mL) > AuNP-QDot646-MB (LOD =2.9 copies/mL) > AgNP-QDot646-MB (LOD =7.6 copies/mL). The LSPR-mediated fluorescence signal was stronger for the bimetallic plasmonic NP-QDots than the single metallic plasmonic NP-QDots. The plasmonic NP-QDot-MB biosensor probes exhibited excellent selectivity toward ZIKV RNA and could serve as potential diagnostic probes for the point-of care detection of the virus.
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localized surface plasmon resonance mediated fluorescence signals in plasmonic Nanoparticle Quantum Dot hybrids for ultrasensitive zika virus rna detection via hairpin hybridization assays
Biosensors and Bioelectronics, 2017Co-Authors: Oluwasesan Adegoke, Masahiro Morita, Tatsuya Kato, Tetsuro Suzuki, Masahito Ito, Enoch Y. ParkAbstract:The current epidemic caused by the Zika virus (ZIKV) and the devastating effects of this virus on fetal development, which result in an increased incidence of congenital microcephaly symptoms, have prompted the World Health Organization (WHO) to declare the ZIKV a public health issue of global concern. Efficient probes that offer high detection sensitivity and specificity are urgently required to aid in the point-of-care treatment of the virus. In this study, we show that localized surface plasmon resonance (LSPR) signals from plasmonic Nanoparticles (NPs) can be used to mediate the fluorescence signal from semiconductor Quantum Dot (QDot) nanocrystals in a molecular beacon (MB) biosensor probe for ZIKV RNA detection. Four different plasmonic NPs functionalized with 3-mercaptopropionic acid (MPA), namely MPA-AgNPs, MPA-AuNPs, core/shell (CS) Au/AgNPs, and alloyed AuAgNPs, were synthesized and conjugated to L-glutathione-capped CdSeS alloyed QDots to form the respective LSPR-mediated fluorescence nanohybrid. The concept of the plasmonic NP-QDot-MB biosensor involves using LSPR from the plasmonic NPs to mediate a fluorescence signal to the QDots, triggered by the hybridization of the target ZIKV RNA with the DNA loop sequence of the MB. The extent of the fluorescence enhancement based on ZIKV RNA detection was proportional to the LSPR-mediated fluorescence signal. The limits of detection (LODs) of the nanohybrids were as follows: alloyed AuAgNP-QDot646-MB (1.7 copies/mL)) > CS Au/AgNP-QDot646-MB (LOD =2.4 copies/mL) > AuNP-QDot646-MB (LOD =2.9 copies/mL) > AgNP-QDot646-MB (LOD =7.6 copies/mL). The LSPR-mediated fluorescence signal was stronger for the bimetallic plasmonic NP-QDots than the single metallic plasmonic NP-QDots. The plasmonic NP-QDot-MB biosensor probes exhibited excellent selectivity toward ZIKV RNA and could serve as potential diagnostic probes for the point-of care detection of the virus.
Tatsuya Kato - One of the best experts on this subject based on the ideXlab platform.
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localized surface plasmon resonance mediated fluorescence signals in plasmonic Nanoparticle Quantum Dot hybrids for ultrasensitive zika virus rna detection via hairpin hybridization assays
Biosensors and Bioelectronics, 2017Co-Authors: Oluwasesan Adegoke, Masahiro Morita, Tatsuya Kato, Tetsuro Suzuki, Enoch Y. ParkAbstract:The current epidemic caused by the Zika virus (ZIKV) and the devastating effects of this virus on fetal development, which result in an increased incidence of congenital microcephaly symptoms, have prompted the World Health Organization (WHO) to declare the ZIKV a public health issue of global concern. Efficient probes that offer high detection sensitivity and specificity are urgently required to aid in the point-of-care treatment of the virus. In this study, we show that localized surface plasmon resonance (LSPR) signals from plasmonic Nanoparticles (NPs) can be used to mediate the fluorescence signal from semiconductor Quantum Dot (QDot) nanocrystals in a molecular beacon (MB) biosensor probe for ZIKV RNA detection. Four different plasmonic NPs functionalized with 3-mercaptopropionic acid (MPA), namely MPA-AgNPs, MPA-AuNPs, core/shell (CS) Au/AgNPs, and alloyed AuAgNPs, were synthesized and conjugated to L-glutathione-capped CdSeS alloyed QDots to form the respective LSPR-mediated fluorescence nanohybrid. The concept of the plasmonic NP-QDot-MB biosensor involves using LSPR from the plasmonic NPs to mediate a fluorescence signal to the QDots, triggered by the hybridization of the target ZIKV RNA with the DNA loop sequence of the MB. The extent of the fluorescence enhancement based on ZIKV RNA detection was proportional to the LSPR-mediated fluorescence signal. The limits of detection (LODs) of the nanohybrids were as follows: alloyed AuAgNP-QDot646-MB (1.7 copies/mL)) > CS Au/AgNP-QDot646-MB (LOD =2.4 copies/mL) > AuNP-QDot646-MB (LOD =2.9 copies/mL) > AgNP-QDot646-MB (LOD =7.6 copies/mL). The LSPR-mediated fluorescence signal was stronger for the bimetallic plasmonic NP-QDots than the single metallic plasmonic NP-QDots. The plasmonic NP-QDot-MB biosensor probes exhibited excellent selectivity toward ZIKV RNA and could serve as potential diagnostic probes for the point-of care detection of the virus.
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localized surface plasmon resonance mediated fluorescence signals in plasmonic Nanoparticle Quantum Dot hybrids for ultrasensitive zika virus rna detection via hairpin hybridization assays
Biosensors and Bioelectronics, 2017Co-Authors: Oluwasesan Adegoke, Masahiro Morita, Tatsuya Kato, Tetsuro Suzuki, Masahito Ito, Enoch Y. ParkAbstract:The current epidemic caused by the Zika virus (ZIKV) and the devastating effects of this virus on fetal development, which result in an increased incidence of congenital microcephaly symptoms, have prompted the World Health Organization (WHO) to declare the ZIKV a public health issue of global concern. Efficient probes that offer high detection sensitivity and specificity are urgently required to aid in the point-of-care treatment of the virus. In this study, we show that localized surface plasmon resonance (LSPR) signals from plasmonic Nanoparticles (NPs) can be used to mediate the fluorescence signal from semiconductor Quantum Dot (QDot) nanocrystals in a molecular beacon (MB) biosensor probe for ZIKV RNA detection. Four different plasmonic NPs functionalized with 3-mercaptopropionic acid (MPA), namely MPA-AgNPs, MPA-AuNPs, core/shell (CS) Au/AgNPs, and alloyed AuAgNPs, were synthesized and conjugated to L-glutathione-capped CdSeS alloyed QDots to form the respective LSPR-mediated fluorescence nanohybrid. The concept of the plasmonic NP-QDot-MB biosensor involves using LSPR from the plasmonic NPs to mediate a fluorescence signal to the QDots, triggered by the hybridization of the target ZIKV RNA with the DNA loop sequence of the MB. The extent of the fluorescence enhancement based on ZIKV RNA detection was proportional to the LSPR-mediated fluorescence signal. The limits of detection (LODs) of the nanohybrids were as follows: alloyed AuAgNP-QDot646-MB (1.7 copies/mL)) > CS Au/AgNP-QDot646-MB (LOD =2.4 copies/mL) > AuNP-QDot646-MB (LOD =2.9 copies/mL) > AgNP-QDot646-MB (LOD =7.6 copies/mL). The LSPR-mediated fluorescence signal was stronger for the bimetallic plasmonic NP-QDots than the single metallic plasmonic NP-QDots. The plasmonic NP-QDot-MB biosensor probes exhibited excellent selectivity toward ZIKV RNA and could serve as potential diagnostic probes for the point-of care detection of the virus.
