The Experts below are selected from a list of 5943 Experts worldwide ranked by ideXlab platform

Perry K W Ng - One of the best experts on this subject based on the ideXlab platform.

  • Natural biopolymer based nanocomposite films for packaging applications
    Critical Reviews in Food Science and Nutrition, 2007
    Co-Authors: Jong-whan Rhim, Perry K W Ng
    Abstract:

    Concerns on environmental waste problems caused by non-biodegradable petrochemical-based plastic packaging materials as well as the consumer's demand for high quality food products has caused an increasing interest in developing biodegradable packaging materials using annually renewable Natural Biopolymers such as polysaccharides and proteins. Inherent shortcomings of Natural polymer-based packaging materials such as low mechanical properties and low water resistance can be recovered by applying a nanocomposite technology. Polymer nanocomposites, especially Natural biopolymer-layered silicate nanocomposites, exhibit markedly improved packaging properties due to their nanometer size dispersion. These improvements include increased modulus and strength, decreased gas permeability, and increased water resistance. Additionally, biologically active ingredients can be added to impart the desired functional properties to the resulting packaging materials. Consequently, Natural biopolymer-based nanocomposite pack...

K.p. Sandeep - One of the best experts on this subject based on the ideXlab platform.

  • Recent Advances in Biopolymers and Biopolymer-Based Nanocomposites for Food Packaging Materials
    Critical Reviews in Food Science and Nutrition, 2012
    Co-Authors: X. Z. Tang, Shirin Alavi, Sajid Alavi, P Kumar, K.p. Sandeep
    Abstract:

    Plastic packaging for food and non-food applications is non-biodegradable, and also uses up valuable and scarce non-renewable resources like petroleum. With the current focus on exploring alternatives to petroleum and emphasis on reduced environmental impact, research is increasingly being directed at development of biodegradable food packaging from biopolymer-based materials. The proposed paper will present a review of recent developments in biopolymer-based food packaging materials including Natural Biopolymers (such as starches and proteins), synthetic Biopolymers (such as poly lactic acid), biopolymer blends, and nanocomposites based on Natural and synthetic Biopolymers. The paper will discuss the various techniques that have been used for developing cost-effective biodegradable packaging materials with optimum mechanical strength and oxygen and moisture barrier properties. This is a timely review as there has been a recent renewed interest in research studies, both in the industry and academia, towards development of a new generation of biopolymer-based food packaging materials with possible applications in other areas.

Martijn Van Griensven - One of the best experts on this subject based on the ideXlab platform.

  • a graded porous composite of Natural Biopolymers and octacalcium phosphate guides osteochondral differentiation of stem cells
    Advanced Healthcare Materials, 2021
    Co-Authors: Elisabeth Amann, Amisel Amirall, Albina R Franco, Patrina S P Poh, Francisco Sola J Duenas, Gaston Fuentes Estevez, Isabel B Leonor, Rui L Reis, Martijn Van Griensven
    Abstract:

    Lesions involving the osteochondral unit are difficult to treat. Biomimetic scaffolds are previously shown as promising alternative. Such devices often lack multiple functional layers that mimic bone, cartilage, and the interface. In this study, multilayered scaffolds are developed based on the use of Natural extracellular matrix (ECM)-like Biopolymers. Particular attention is paid to obtain a complex matrix that mimics the native osteochondral transition. Porous, sponge-like chitosan-collagen-octacalcium phosphate (OCP) scaffolds are obtained. Collagen content increases while the amount of OCP particles decreases toward the cartilage layer. The scaffolds are bioactive as a mineral layer is deposited containing hydroxyapatite at the bony side. The scaffolds stimulate proliferation of human adipose-derived mesenchymal stem cells, but the degree of proliferation depends on the cell seeding density. The scaffolds give rise to a zone-specific gene expression. RUNX2, COL1A1, BGLAP, and SPP1 are upregulated in the bony layer of the scaffold. SOX9 is upregulated concomitant with COL2A1 expression in the cartilage zone. Mineralization in presence of the cells is prominent in the bone area with Ca and P steadily increasing over time. These results are encouraging for the fabrication of biomimetic scaffolds using ECM-like materials and featuring gradients that mimic native tissues and their interface.

Patrina S P Poh - One of the best experts on this subject based on the ideXlab platform.

  • a graded porous composite of Natural Biopolymers and octacalcium phosphate guides osteochondral differentiation of stem cells
    Advanced Healthcare Materials, 2021
    Co-Authors: Elisabeth Amann, Amisel Amirall, Albina R Franco, Patrina S P Poh, Francisco Sola J Duenas, Gaston Fuentes Estevez, Isabel B Leonor, Rui L Reis, Martijn Van Griensven
    Abstract:

    Lesions involving the osteochondral unit are difficult to treat. Biomimetic scaffolds are previously shown as promising alternative. Such devices often lack multiple functional layers that mimic bone, cartilage, and the interface. In this study, multilayered scaffolds are developed based on the use of Natural extracellular matrix (ECM)-like Biopolymers. Particular attention is paid to obtain a complex matrix that mimics the native osteochondral transition. Porous, sponge-like chitosan-collagen-octacalcium phosphate (OCP) scaffolds are obtained. Collagen content increases while the amount of OCP particles decreases toward the cartilage layer. The scaffolds are bioactive as a mineral layer is deposited containing hydroxyapatite at the bony side. The scaffolds stimulate proliferation of human adipose-derived mesenchymal stem cells, but the degree of proliferation depends on the cell seeding density. The scaffolds give rise to a zone-specific gene expression. RUNX2, COL1A1, BGLAP, and SPP1 are upregulated in the bony layer of the scaffold. SOX9 is upregulated concomitant with COL2A1 expression in the cartilage zone. Mineralization in presence of the cells is prominent in the bone area with Ca and P steadily increasing over time. These results are encouraging for the fabrication of biomimetic scaffolds using ECM-like materials and featuring gradients that mimic native tissues and their interface.

Xianhong Wang - One of the best experts on this subject based on the ideXlab platform.

  • a versatile strategy for the synthesis of sequence defined peptoids with side chain and backbone diversity via amino acid building blocks
    Chemical Science, 2019
    Co-Authors: Shixue Wang, Yue Tao, Jianqun Wang, Youhua Tao, Xianhong Wang
    Abstract:

    Designing artificial macromolecules with absolute sequence order is still a long-term challenge in polymer chemistry as opposed to Natural Biopolymers with perfectly defined sequences like proteins and DNA. Herein, we combined amino acid building blocks and iterative Ugi reactions for the de novo design and synthesis of sequence-defined peptoids. The highly efficient strategy provided excellent yields and enables multigram-scale synthesis of perfectly defined peptoids. This new strategy furnishes the broad structural diversity of side chains, as well as backbones. Importantly, the overall hydrophobicity and lower critical solution temperature (LCST) behaviours of these precisely defined peptoids can be logically altered by variation of the sequence. By following the same Ugi chemistry, these peptoids are also conjugated to DNA in a simple way, facilitating the development of novel therapeutics.