The Experts below are selected from a list of 319791 Experts worldwide ranked by ideXlab platform
Jing Su - One of the best experts on this subject based on the ideXlab platform.
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microalgae derived cellulose inorganic nanocomposite rattle type microspheres as an advanced sensor for pollutant detection
Chemical Engineering Journal, 2020Co-Authors: Lei Bi, Chen Wang, Yiping Chen, Jing SuAbstract:Abstract The versatility of rattle-type microspheres is tightly correlated with the composition and morphology. Exploring advanced rattle-type microspheres with simultaneous controllable composition and micro/nanostructures via novel designed and regulated strategies may have great advantages for performing complex tasks. Herein, cellulose/inorganic hybrid rattle-type microspheres, produced using microalgae as Natural Chemical reservoirs, microreactors and matrix, is reported. By adjusting only pH and temperature, rattle-type microspheres with simultaneously controllable mesoporous outer shells (19.4–46.3 nm) and multicomponent nano-cores (i.e., Ca5(PO4)3OH and Fe3O4/MgFe2O4) are obtained using microalgae as single-source precursors. Especially, the rattle-type microspheres-mediated immunosensor shows ultrahigh sensitivity for the detection of trace microcystin-LR in complex real water samples with a limit of quantitation of 0.05 ng/mL, which is a 10-fold improvement compared with conventional enzyme linked immunosorbent assays. Enhancement of the sensitivity is due to the tailorability and functionality in both the hollow shells and the cores of the rattle-type microspheres. The finely controlled pore-size, void space and Natural carboxyl groups of the shell are beneficial for enzymes loading and for bio-conjugation. The cores contain magnetite and hydroxyapatite nano-particles, which can be utilised for magnetic separation and for anchoring more enzymes, resulting in considerable signal amplification. This work opens up a new and green route for the construction of rattle-type microspheres with tunable compositions and porosities, which makes it a flexible platform for various applications in immunoassay, biosensors, enrichment and separation of target substances, drug-delivery, and environmental remediation.
Ann L. Rypstra - One of the best experts on this subject based on the ideXlab platform.
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Glyphosate-Based Herbicide Has Contrasting Effects on Prey Capture by Two Co-Occurring Wolf Spider Species
Journal of Chemical Ecology, 2013Co-Authors: Sandra Rittman, Samuel C Evans, Kerri M Wrinn, Alex W. Webb, Ann L. RypstraAbstract:Anthropogenic substances have the potential to affect animal behavior either because they present a novel stimulus or because they interfere with Natural Chemical communication pathways. Such shifts can alter the dynamic between predators and potential prey, which might affect population success as well as the strength of food web linkages. We examined the foraging of two wolf spiders, Tigrosa helluo and Pardosa milvina (Araneae, Lycosidae), that are abundant in agroecosystems where they are routinely exposed to herbicides. We tested the hypothesis that the presence of a commercial formulation of a glyphosate-based herbicide would affect the prey capture behavior of these two wolf spiders. We tested the larger Tigrosa foraging on Pardosa or crickets ( Acheta domesticus ) and the smaller Pardosa foraging on crickets. Tigrosa subdued crickets more quickly and with fewer lunges than it took them to capture Pardosa . The presence of herbicide allowed Tigrosa to orient toward and capture both prey species more quickly but it did not affect the number of lunges required to subdue either prey. Herbicide did not affect the timing of prey capture for Pardosa but it did cause them to use more lunges in the process. Thus, herbicide had contrasting effects on foraging behavior of these two agrobiont predators, which means that it could shift the direction and strength of food web linkages in complex ways.
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predator cues and an herbicide affect activity and emigration in an agrobiont wolf spider
Chemosphere, 2012Co-Authors: Kerri M Wrinn, Samuel C Evans, Ann L. RypstraAbstract:Animals use Chemical cues for signaling between species. However, anthropogenic Chemicals might interrupt this Natural Chemical information flow, with potential impacts on predator–prey interactions. Our goal was to explore how Buccaneer® Plus, a common herbicide similar to Round-up® (active ingredient glyphosate), affected the interactions between intraguild predators. The wolf spider Pardosa milvina (Hentz, 1844) is numerically dominant in agricultural systems across the eastern United States, and often falls prey to or competes with the larger wolf spider, Hogna helluo (Walckenaer, 1837) and/or the carabid beetle, Scarites quadriceps (Chaudoir, 1843). We tested the effects of Chemical cues from these intraguild predators and exposure to herbicide on the activity, emigration, and survival of P. milvina using a full-factorial laboratory experiment. Both predator cues and herbicide led to a decrease in movement by P. milvina. However, although H. helluo cues alone decreased movement, S. quadriceps cues only decreased movement when combined with herbicide. These results indicate that predation risk and herbicide application likely interact in complex ways to affect the movement of a major arthropod predator in agricultural systems, and thus may have complex effects on the food web.
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effects of a glyphosate based herbicide on mate location in a wolf spider that inhabits agroecosystems
Chemosphere, 2011Co-Authors: Laurie M Griesinger, Samuel C Evans, Ann L. RypstraAbstract:Abstract Chemical communication is important to many arthropod species but the potential exists for anthropogenic Chemicals to disrupt information flow. Although glyphosate-based herbicides are not acutely toxic to arthropods, little is known regarding their effects on Natural Chemical communication pathways. The wolf spider, Pardosa milvina, is abundant in agroecosystems where herbicides are regularly applied and uses air- and substrate-borne Chemical signals extensively during mating. The aim of this study was to examine effects of a commercial formulation of a glyphosate-based herbicide on the ability of males to find females. In the field, virgin females, when hidden inside pitfall traps with herbicide, attracted fewer males than females with water. Likewise females in traps with a ring of herbicide surrounding the opening were less likely to attract males than those in traps surrounded by water. We explored the reaction of males to any airborne component of the herbicide in a laboratory two-choice olfactometer experiment. When no female pheromones were present, males were equally likely to select herbicide or water treated corridors and they all moved through the apparatus at similar speeds. When female pheromones were present, the males that selected control corridors moved more slowly than those that selected herbicide and, if we control for the initial decision time, more males selected the control corridors over the herbicide. These data suggest that glyphosate-based herbicides are “info-disruptors” that alter the ability of males to detect and/or react fully to female signals.
Lijuan Mei - One of the best experts on this subject based on the ideXlab platform.
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erythritol attenuates postprandial blood glucose by inhibiting α glucosidase
Journal of Agricultural and Food Chemistry, 2018Co-Authors: Huaixiu Wen, Bowen Tang, Alan J Stewart, Yanduo Tao, Yun Shao, Yulei Cui, Huilan Yue, Jinjin Pei, Zenggen Liu, Lijuan MeiAbstract:Diabetes mellitus (DM) is a serious metabolic disorder, where impaired postprandial blood glucose regulation often leads to severe health complications. The Natural Chemical erythritol is a C4 polyol approved by the U.S. Food and Drug Administration for use as a sweetener. Here, we examined a potential role for erythritol in the control of postprandial blood glucose levels in DM. An anti-postprandial hyperglycemia effect upon erythritol administration (500 mg kg-1) was demonstrated in alloxan-induced DM model mice by monitoring changes in blood glucose after intragastric administration of drugs and starch. We also found that erythritol most likely exerts its anti-postprandial hyperglycemic activities by inhibiting α-glucosidase in a competitive manner. This was supported by enzyme activity assays and molecular modeling experiments. In the latter experiments, it was possible to successfully dock erythritol into the catalytic pocket of α-glucosidase, with the resultant interaction likely driven by electrostatic interactions involving Asp215, Asp69, and Arg446 residues. This study suggests that erythritol may not only serve as a glucose substitute but also be a useful agent in the treatment of DM to help manage postprandial blood glucose levels.
Chen Wang - One of the best experts on this subject based on the ideXlab platform.
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microalgae derived cellulose inorganic nanocomposite rattle type microspheres as an advanced sensor for pollutant detection
Chemical Engineering Journal, 2020Co-Authors: Lei Bi, Chen Wang, Yiping Chen, Jing SuAbstract:Abstract The versatility of rattle-type microspheres is tightly correlated with the composition and morphology. Exploring advanced rattle-type microspheres with simultaneous controllable composition and micro/nanostructures via novel designed and regulated strategies may have great advantages for performing complex tasks. Herein, cellulose/inorganic hybrid rattle-type microspheres, produced using microalgae as Natural Chemical reservoirs, microreactors and matrix, is reported. By adjusting only pH and temperature, rattle-type microspheres with simultaneously controllable mesoporous outer shells (19.4–46.3 nm) and multicomponent nano-cores (i.e., Ca5(PO4)3OH and Fe3O4/MgFe2O4) are obtained using microalgae as single-source precursors. Especially, the rattle-type microspheres-mediated immunosensor shows ultrahigh sensitivity for the detection of trace microcystin-LR in complex real water samples with a limit of quantitation of 0.05 ng/mL, which is a 10-fold improvement compared with conventional enzyme linked immunosorbent assays. Enhancement of the sensitivity is due to the tailorability and functionality in both the hollow shells and the cores of the rattle-type microspheres. The finely controlled pore-size, void space and Natural carboxyl groups of the shell are beneficial for enzymes loading and for bio-conjugation. The cores contain magnetite and hydroxyapatite nano-particles, which can be utilised for magnetic separation and for anchoring more enzymes, resulting in considerable signal amplification. This work opens up a new and green route for the construction of rattle-type microspheres with tunable compositions and porosities, which makes it a flexible platform for various applications in immunoassay, biosensors, enrichment and separation of target substances, drug-delivery, and environmental remediation.
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Pristimerin triggers AIF-dependent programmed necrosis in glioma cells via activation of JNK
Cancer letters, 2016Co-Authors: Hongwei Zhao, Chen Wang, Zijian Zhou, Yong Jin, Zongqi Wang, Linjie Zheng, Kai Liu, Tianfei Luo, Dong ZhuAbstract:Programmed necrosis is established as a new form of programmed cell death and is emerging as a new strategy of treatment for cancers. Pristimerin is a Natural Chemical with anti-tumor effect despite the fact that its mechanism remains poorly understood. In this study, we used glioma cell lines and mice model of xenograft glioma to investigate the effect of pristimerin on glioma and its underlying mechanism. We found that pristimerin inhibited the viabilities of glioma cells in vitro and the growth of xenograft gliomas in vivo, which was accompanied by upregulation of JNK and phosphor-JNK, nuclear accumulation of AIF, and elevation in the ratio of Bax/Bcl-2. In vitro studies showed that pristimerin induced necrosis in glioma cells, as well as mitochondrial depolarization, overproduction of ROS and reduction of GSH. Ablation of AIF level with SiRNA mitigated pristimerin-induced nuclear accumulation of AIF and prevented necrosis in glioma cells. Moreover, pharmacological inhibition of JNK with SP600125 or knockdown of its level with SiRNA reversed mitochondrial depolarization attenuated the elevation of Bax/Bcl-2 and suppressed nuclear accumulation of AIF. Further, inhibition of ROS with NAC not only rescued glioma cell necrosis but also suppressed JNK activation, mitigated Bax/Bcl-2 ratio, maintained mitochondrial membrane potential, and inhibited AIF translocation into nucleus. Therefore, we demonstrated first in this study that pristimerin triggered AIF-dependent necroptosis in glioma cells via induction of mitochondrial dysfunction by activation of JNK through overproduction of ROS. These results suggest that pristimerin has potential therapeutic effects on glioma.
Lei Bi - One of the best experts on this subject based on the ideXlab platform.
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microalgae derived cellulose inorganic nanocomposite rattle type microspheres as an advanced sensor for pollutant detection
Chemical Engineering Journal, 2020Co-Authors: Lei Bi, Chen Wang, Yiping Chen, Jing SuAbstract:Abstract The versatility of rattle-type microspheres is tightly correlated with the composition and morphology. Exploring advanced rattle-type microspheres with simultaneous controllable composition and micro/nanostructures via novel designed and regulated strategies may have great advantages for performing complex tasks. Herein, cellulose/inorganic hybrid rattle-type microspheres, produced using microalgae as Natural Chemical reservoirs, microreactors and matrix, is reported. By adjusting only pH and temperature, rattle-type microspheres with simultaneously controllable mesoporous outer shells (19.4–46.3 nm) and multicomponent nano-cores (i.e., Ca5(PO4)3OH and Fe3O4/MgFe2O4) are obtained using microalgae as single-source precursors. Especially, the rattle-type microspheres-mediated immunosensor shows ultrahigh sensitivity for the detection of trace microcystin-LR in complex real water samples with a limit of quantitation of 0.05 ng/mL, which is a 10-fold improvement compared with conventional enzyme linked immunosorbent assays. Enhancement of the sensitivity is due to the tailorability and functionality in both the hollow shells and the cores of the rattle-type microspheres. The finely controlled pore-size, void space and Natural carboxyl groups of the shell are beneficial for enzymes loading and for bio-conjugation. The cores contain magnetite and hydroxyapatite nano-particles, which can be utilised for magnetic separation and for anchoring more enzymes, resulting in considerable signal amplification. This work opens up a new and green route for the construction of rattle-type microspheres with tunable compositions and porosities, which makes it a flexible platform for various applications in immunoassay, biosensors, enrichment and separation of target substances, drug-delivery, and environmental remediation.