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John Stradling - One of the best experts on this subject based on the ideXlab platform.
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Neck Circumference and other clinical features in the diagnosis of the obstructive sleep apnoea syndrome.
Thorax, 1992Co-Authors: R. J. O. Davies, N. J. Ali, John StradlingAbstract:BACKGROUND: Neck Circumference has been suggested to be more predictive of obstructive sleep apnoea than general obesity, but the statistical validity of this conclusion has been questioned. Combining Neck Circumference with other signs and symptoms may allow the clinical diagnosis or exclusion of sleep apnoea to be made with reasonable confidence. This study examines these issues. METHODS: One hundred and fifty patients referred to a sleep clinic for investigation of sleep related breathing disorders completed a questionnaire covering daytime sleepiness, snoring, driving, and nasal disease. Body mass index and Neck Circumference corrected for height were measured and obstructive sleep apnoea severity was quantified as number of dips in arterial oxygen saturation (SaO2) of more than 4% per hour of polysomnography. Multiple linear regression was used retrospectively to identify independent predictors of SaO2 dip rate, and the model derived was then prospectively tested in a further 85 subjects. RESULTS: The retrospective analysis showed that the question "Do you fall asleep during the day, particularly when not busy?" was the best questionnaire predictor of variance in the SaO2 dip rate (r2 = 0.13); no other question improved this correlation. This analysis also showed that neither body mass index nor any of the questionnaire variables improved the amount of variance explained by height corrected Neck Circumference alone (r2 = 0.35). A statistically similar prospective analysis confirmed this relationship (r2 = 0.38). CONCLUSIONS: Prospective study of these patients referred to a sleep clinic with symptoms suggesting sleep apnoea shows that Neck Circumference corrected for height is more useful as a predictor of obstructive sleep apnoea than general obesity. None of the questionnaire variables examined add to its predictive power, but alone it is inadequate to avoid the need for sleep studies to diagnose this disease.
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The relationship between Neck Circumference, radiographic pharyngeal anatomy, and the obstructive sleep apnoea syndrome
The European respiratory journal, 1990Co-Authors: R. J. O. Davies, John StradlingAbstract:We have studied the predictive importance of Neck Circumference, obesity, and several radiographic pharyngeal dimensions for obstructive sleep apnoea (OSA), in 66 patients. OSA was quantified as the mean hourly number of greater than 4% dips in arterial oxygen saturation during sleep. Neck Circumference (correlation coefficient (r) = 0.63, 95% confidence interval (C.I.) 0.46-0.76), obesity index (r = 0.54, 95% C.I. 0.39-0.69), hyoid position (r = 0.40, 95% C.I. 0.17-0.59), soft palate length (r = 0.31, 95% C.I. 0.08-0.51), and hard palate-to-spine angle (r = 0.29, 95% C.I. 0.04-0.49), correlated significantly with saturation dips in single regression analysis. In stepwise multiple linear regression analysis (saturation dip rate as the dependent variable), only Neck size and retroglossal space were significant independent correlates (total r2 = 0.42, 95% C.I. 0.22-0.61, p less than 0.0001). We conclude that the relationships between general obesity, hyoid position, soft palate length, and OSA are probably secondary to variation in Neck Circumference.
R. J. O. Davies - One of the best experts on this subject based on the ideXlab platform.
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Neck Circumference and other clinical features in the diagnosis of the obstructive sleep apnoea syndrome.
Thorax, 1992Co-Authors: R. J. O. Davies, N. J. Ali, John StradlingAbstract:BACKGROUND: Neck Circumference has been suggested to be more predictive of obstructive sleep apnoea than general obesity, but the statistical validity of this conclusion has been questioned. Combining Neck Circumference with other signs and symptoms may allow the clinical diagnosis or exclusion of sleep apnoea to be made with reasonable confidence. This study examines these issues. METHODS: One hundred and fifty patients referred to a sleep clinic for investigation of sleep related breathing disorders completed a questionnaire covering daytime sleepiness, snoring, driving, and nasal disease. Body mass index and Neck Circumference corrected for height were measured and obstructive sleep apnoea severity was quantified as number of dips in arterial oxygen saturation (SaO2) of more than 4% per hour of polysomnography. Multiple linear regression was used retrospectively to identify independent predictors of SaO2 dip rate, and the model derived was then prospectively tested in a further 85 subjects. RESULTS: The retrospective analysis showed that the question "Do you fall asleep during the day, particularly when not busy?" was the best questionnaire predictor of variance in the SaO2 dip rate (r2 = 0.13); no other question improved this correlation. This analysis also showed that neither body mass index nor any of the questionnaire variables improved the amount of variance explained by height corrected Neck Circumference alone (r2 = 0.35). A statistically similar prospective analysis confirmed this relationship (r2 = 0.38). CONCLUSIONS: Prospective study of these patients referred to a sleep clinic with symptoms suggesting sleep apnoea shows that Neck Circumference corrected for height is more useful as a predictor of obstructive sleep apnoea than general obesity. None of the questionnaire variables examined add to its predictive power, but alone it is inadequate to avoid the need for sleep studies to diagnose this disease.
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The relationship between Neck Circumference, radiographic pharyngeal anatomy, and the obstructive sleep apnoea syndrome
The European respiratory journal, 1990Co-Authors: R. J. O. Davies, John StradlingAbstract:We have studied the predictive importance of Neck Circumference, obesity, and several radiographic pharyngeal dimensions for obstructive sleep apnoea (OSA), in 66 patients. OSA was quantified as the mean hourly number of greater than 4% dips in arterial oxygen saturation during sleep. Neck Circumference (correlation coefficient (r) = 0.63, 95% confidence interval (C.I.) 0.46-0.76), obesity index (r = 0.54, 95% C.I. 0.39-0.69), hyoid position (r = 0.40, 95% C.I. 0.17-0.59), soft palate length (r = 0.31, 95% C.I. 0.08-0.51), and hard palate-to-spine angle (r = 0.29, 95% C.I. 0.04-0.49), correlated significantly with saturation dips in single regression analysis. In stepwise multiple linear regression analysis (saturation dip rate as the dependent variable), only Neck size and retroglossal space were significant independent correlates (total r2 = 0.42, 95% C.I. 0.22-0.61, p less than 0.0001). We conclude that the relationships between general obesity, hyoid position, soft palate length, and OSA are probably secondary to variation in Neck Circumference.
Bo Feng - One of the best experts on this subject based on the ideXlab platform.
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Neck Circumference is a valuable tool for identifying metabolic syndrome and obesity in Chinese elder subjects: a community-based study.
Diabetes metabolism research and reviews, 2014Co-Authors: Qun Yan, Dongmei Sun, Qinghu Zheng, Bo FengAbstract:Objective We aim to explore the relationship of Neck Circumference to metabolic syndrome (MetS) and obesity in Chinese elders and to establish cut-off points of the Neck Circumference for MetS and obesity. Methods Cross-sectional analysis for a population sample of 2092 individuals aged over 65 years, representative of East China elders. MetS was identified according to the 2004 Chinese Diabetes Society criteria. Results Neck Circumference was correlated with body mass index (r = 0.70, p = 0.000 in men, and r = 0.73, p = 0.000 in women) and waist Circumference (waist Circumference; r = 0.70, p = 0.000 in men, and r = 0.72, p = 0.000 in women). According to Neck Circumference quartile, the prevalence of MetS and its components were increased significantly from Q1 to Q4 (p for trend
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Neck Circumference is a valuable tool for identifying metabolic syndrome and obesity in chinese elder subjects a community based study
Diabetes-metabolism Research and Reviews, 2014Co-Authors: Qun Yan, Dongmei Sun, Qinghu Zheng, Bo FengAbstract:Objective We aim to explore the relationship of Neck Circumference to metabolic syndrome (MetS) and obesity in Chinese elders and to establish cut-off points of the Neck Circumference for MetS and obesity. Methods Cross-sectional analysis for a population sample of 2092 individuals aged over 65 years, representative of East China elders. MetS was identified according to the 2004 Chinese Diabetes Society criteria. Results Neck Circumference was correlated with body mass index (r = 0.70, p = 0.000 in men, and r = 0.73, p = 0.000 in women) and waist Circumference (waist Circumference; r = 0.70, p = 0.000 in men, and r = 0.72, p = 0.000 in women). According to Neck Circumference quartile, the prevalence of MetS and its components were increased significantly from Q1 to Q4 (p for trend <0.001) in both genders. Binary logistic regression analysis revealed that both waist Circumference and Neck Circumference were independent predictors of Mets, with odds ratios (95% confidence interval) 1.11 (1.08–1.15; p = 0.044) and 1.17 (1.07–1.28; p = 0.000), respectively, in men and 1.08 (1.05–1.10; p = 0.000) and 1.31 (1.21–1.42; p = 0.000), respectively, in women. As for obesity, the significant independent indicators in both genders were also waist Circumference and Neck Circumference (all p < 0.01). In the receiver operating characteristic curves, both the optimal cut-off points of Neck Circumference for MetS and obesity were 38 cm in men and 35 cm in women. Conclusions The Neck Circumference, as waist Circumference, is also a valuable tool for identifying MetS and obesity, with established cut-off points for the prediction of MetS and obesity in Chinese elders. Copyright © 2013 John Wiley & Sons, Ltd.
Qun Yan - One of the best experts on this subject based on the ideXlab platform.
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Neck Circumference is a valuable tool for identifying metabolic syndrome and obesity in Chinese elder subjects: a community-based study.
Diabetes metabolism research and reviews, 2014Co-Authors: Qun Yan, Dongmei Sun, Qinghu Zheng, Bo FengAbstract:Objective We aim to explore the relationship of Neck Circumference to metabolic syndrome (MetS) and obesity in Chinese elders and to establish cut-off points of the Neck Circumference for MetS and obesity. Methods Cross-sectional analysis for a population sample of 2092 individuals aged over 65 years, representative of East China elders. MetS was identified according to the 2004 Chinese Diabetes Society criteria. Results Neck Circumference was correlated with body mass index (r = 0.70, p = 0.000 in men, and r = 0.73, p = 0.000 in women) and waist Circumference (waist Circumference; r = 0.70, p = 0.000 in men, and r = 0.72, p = 0.000 in women). According to Neck Circumference quartile, the prevalence of MetS and its components were increased significantly from Q1 to Q4 (p for trend
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Neck Circumference is a valuable tool for identifying metabolic syndrome and obesity in chinese elder subjects a community based study
Diabetes-metabolism Research and Reviews, 2014Co-Authors: Qun Yan, Dongmei Sun, Qinghu Zheng, Bo FengAbstract:Objective We aim to explore the relationship of Neck Circumference to metabolic syndrome (MetS) and obesity in Chinese elders and to establish cut-off points of the Neck Circumference for MetS and obesity. Methods Cross-sectional analysis for a population sample of 2092 individuals aged over 65 years, representative of East China elders. MetS was identified according to the 2004 Chinese Diabetes Society criteria. Results Neck Circumference was correlated with body mass index (r = 0.70, p = 0.000 in men, and r = 0.73, p = 0.000 in women) and waist Circumference (waist Circumference; r = 0.70, p = 0.000 in men, and r = 0.72, p = 0.000 in women). According to Neck Circumference quartile, the prevalence of MetS and its components were increased significantly from Q1 to Q4 (p for trend <0.001) in both genders. Binary logistic regression analysis revealed that both waist Circumference and Neck Circumference were independent predictors of Mets, with odds ratios (95% confidence interval) 1.11 (1.08–1.15; p = 0.044) and 1.17 (1.07–1.28; p = 0.000), respectively, in men and 1.08 (1.05–1.10; p = 0.000) and 1.31 (1.21–1.42; p = 0.000), respectively, in women. As for obesity, the significant independent indicators in both genders were also waist Circumference and Neck Circumference (all p < 0.01). In the receiver operating characteristic curves, both the optimal cut-off points of Neck Circumference for MetS and obesity were 38 cm in men and 35 cm in women. Conclusions The Neck Circumference, as waist Circumference, is also a valuable tool for identifying MetS and obesity, with established cut-off points for the prediction of MetS and obesity in Chinese elders. Copyright © 2013 John Wiley & Sons, Ltd.
Guang-ran Yang - One of the best experts on this subject based on the ideXlab platform.
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Neck Circumference as a measure of Neck fat and abdominal visceral fat in Chinese adults.
BMC public health, 2014Co-Authors: Fen Zhang, Dong Zhao, Zhong Xin, Shu-qin Guo, Shu-mei Wang, Jian-jun Zhang, Jun Wang, Guang-ran YangAbstract:Background Visceral adipose tissue (VAT) is a unique pathogenic fatty deposit, in that it is closely correlated with risk of cardiovascular diseases. The present study is to investigate the usefulness of Neck Circumference (NC) to indicate VAT.
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Association of Neck Circumference and lipid profile and its effect in predicting dyslipidemia in type 2 diabetes: Beijing Community Diabetes Study (BCDS-10)
2013Co-Authors: Guang-ran Yang, Shen-yuan Yuan, Gang Wan, Liang-xiang Zhu, Ming-xia Yuan, Su-fang Pan, Jian-dong ZhangAbstract:Objective To investigate the association between Neck Circumference and lipid profile in Chinese individuals with type 2 diabetes. Methods Total of 2410 subjects with type 2 diabetes (age 20-80 yrs) were recruited from 15 community health centers in Beijing using a multi-stage random sampling approach. Dyslipidemia was diagnosed according to 2007 Chinese Guidelines on Prevention and Treatment of Dyslipidemia in Adults. Results (1)The study sample consisted of 986 men and 1424 women with a mean Neck Circumference of (36±4)cm. Mean total cholesterol, triglyceride, high-density lipoprotein cholesterol and low-density lipoprotein cholesterol was (5.2±1.1)mmol/L, (1.8±1.2)mmol/L, (1.3±0.4)mmol/L and (3.0±0.9)mmol/L, respectively. (2)Neck Circumference correlated positively with triglyceride (men(r=0.093), women(r=0.077), P 0.05). Receiver operating characteristic analysis showed that the area under the curve for Neck Circumference and low-density lipoprotein cholesterol was 0.527 for men and 0.519 for women (P>0.05). Conclusion In the present study, Neck Circumference is related with lipid profile in Chinese individuals with type 2 diabetes, especially triglyceride and high-density lipoprotein cholesterol. Neck Circumference might be used in a clinical setting as an indicator for screening or evaluating dyslipidemia in type 2 diabetic subjects. Key words: Diabetes, type 2; Neck Circumference; Dyslipidemia; Community
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Neck Circumference positively related with central obesity overweight and metabolic syndrome in chinese subjects with type 2 diabetes beijing community diabetes study 4
Diabetes Care, 2010Co-Authors: Guang-ran Yang, Shen-yuan Yuan, Gang Wan, Liang-xiang Zhu, Jian-dong ZhangAbstract:Objective To investigate the association between Neck Circumference and central obesity, overweight, and metabolic syndrome in Chinese individuals with type 2 diabetes. Research design and methods A total of 3,182 diabetic subjects (aged 20-80 years) were recruited from 15 community health centers in Beijing using a multistage random sampling approach. Results Receiver operating characteristic analysis showed that the area under the curve for Neck Circumference and central obesity was 0.77 for men and 0.75 for women (P Conclusions In the present study, Neck Circumference is positively related with BMI, waist Circumference, and metabolic syndrome in Chinese individuals with type 2 diabetes.
