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Richard Yanagihara - One of the best experts on this subject based on the ideXlab platform.
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Short Report: Phylogenetically Distinct Hantaviruses in the Masked Shrew (Sorex cinereus) and Dusky Shrew (Sorex monticolus) in the United States
2015Co-Authors: Satoru Arai, Joseph A. Cook, Jin-won Song, Shannon N. Bennett, Laarni Sumibcay, Cheryl A. Parmenter, Vivek R. Nerurkar, Terry L. Yates, Andrew Hope, Richard YanagiharaAbstract:Abstract. A limited search for hantaviruses in lung and liver tissues of Sorex shrews (family Soricidae, subfamily Soricinae) revealed phylogenetically distinct hantaviruses in the masked shrew (Sorex cinereus) from Minnesota and in the dusky shrew (Sorex monticolus) from New Mexico and Colorado. The discovery of these shrew-borne hantaviruses, named Ash River virus and Jemez Springs virus, respectively, challenges the long-held dogma that rodents are the sole reservoir hosts and forces a re-examination of their co-evolutionary history. Also, studies now underway are aimed at clarifying the epizootiology and pathogenicity of these new members of the genus Hantavirus. Based on phylogenetic analyses of full-length viral genomic sequences and host mitochondrial DNA (mtDNA) se-quences, hantaviruses segregate into clades that parallel the evolution of murinae, arvicolinae, Neotominae, and sigmo-dontinae rodents.1–4 Whether insectivores (or soricomorphs), which are sympatric with rodents, are involved in the evolu-tionary origins of hantaviruses has not been systematically studied, despite previous reports of hantavirus antigens in tissues of the Eurasian common shrew (Sorex araneus), alpin
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hantaviruses rediscovery and new beginnings
Virus Research, 2014Co-Authors: Richard Yanagihara, Hae Ji Kang, Satoru Arai, Jin-won SongAbstract:Virus and host gene phylogenies, indicating that antigenically distinct hantaviruses (family Bunyaviridae, genus Hantavirus) segregate into clades, which parallel the molecular evolution of rodents belonging to the Murinae, Arvicolinae, Neotominae and Sigmodontinae subfamilies, suggested co-divergence of hantaviruses and their rodent reservoirs. Lately, this concept has been vigorously contested in favor of preferential host switching and local host-specific adaptation. To gain insights into the host range, spatial and temporal distribution, genetic diversity and evolutionary origins of hantaviruses, we employed reverse transcription-polymerase chain reaction to analyze frozen, RNAlater®-preserved and ethanol-fixed tissues from 1546 shrews (9 genera and 47 species), 281 moles (8 genera and 10 species) and 520 bats (26 genera and 53 species), collected in Europe, Asia, Africa and North America during 1980–2012. Thus far, we have identified 24 novel hantaviruses in shrews, moles and bats. That these newfound hantaviruses are geographically widespread and genetically more diverse than those harbored by rodents suggests that the evolutionary history of hantaviruses is far more complex than previously conjectured. Phylogenetic analyses indicate four distinct clades, with the most divergent comprising hantaviruses harbored by the European mole and insectivorous bats, with evidence for both co-divergence and host switching. Future studies will provide new knowledge about the transmission dynamics and pathogenic potential of these newly discovered, still-orphan, non-rodent-borne hantaviruses.
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seewis virus a genetically distinct hantavirus in the eurasian common shrew sorex araneus
Virology Journal, 2007Co-Authors: Jin-won Song, Satoru Arai, Shannon N. Bennett, M Puorger, Monika Hilbe, Richard YanagiharaAbstract:More than 20 years ago, hantaviral antigens were reported in tissues of the Eurasian common shrew (Sorex araneus), Eurasian water shrew (Neomys fodiens) and common mole (Talpa europea), suggesting that insectivores, or soricomorphs, might serve as reservoirs of unique hantaviruses. Using RT-PCR, sequences of a genetically distinct hantavirus, designated Seewis virus (SWSV), were amplified from lung tissue of a Eurasian common shrew, captured in October 2006 in Graubunden, Switzerland. Pair-wise analysis of the full-length S and partial M and L segments of SWSV indicated approximately 55%–72% similarity with hantaviruses harbored by Murinae, Arvicolinae, Neotominae and Sigmodontinae rodents. Phylogenetically, SWSV grouped with other recently identified shrew-borne hantaviruses. Intensified efforts are underway to clarify the genetic diversity of SWSV throughout the geographic range of the Eurasian common shrew, as well as to determine its relevance to human health.
Jin-won Song - One of the best experts on this subject based on the ideXlab platform.
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Short Report: Phylogenetically Distinct Hantaviruses in the Masked Shrew (Sorex cinereus) and Dusky Shrew (Sorex monticolus) in the United States
2015Co-Authors: Satoru Arai, Joseph A. Cook, Jin-won Song, Shannon N. Bennett, Laarni Sumibcay, Cheryl A. Parmenter, Vivek R. Nerurkar, Terry L. Yates, Andrew Hope, Richard YanagiharaAbstract:Abstract. A limited search for hantaviruses in lung and liver tissues of Sorex shrews (family Soricidae, subfamily Soricinae) revealed phylogenetically distinct hantaviruses in the masked shrew (Sorex cinereus) from Minnesota and in the dusky shrew (Sorex monticolus) from New Mexico and Colorado. The discovery of these shrew-borne hantaviruses, named Ash River virus and Jemez Springs virus, respectively, challenges the long-held dogma that rodents are the sole reservoir hosts and forces a re-examination of their co-evolutionary history. Also, studies now underway are aimed at clarifying the epizootiology and pathogenicity of these new members of the genus Hantavirus. Based on phylogenetic analyses of full-length viral genomic sequences and host mitochondrial DNA (mtDNA) se-quences, hantaviruses segregate into clades that parallel the evolution of murinae, arvicolinae, Neotominae, and sigmo-dontinae rodents.1–4 Whether insectivores (or soricomorphs), which are sympatric with rodents, are involved in the evolu-tionary origins of hantaviruses has not been systematically studied, despite previous reports of hantavirus antigens in tissues of the Eurasian common shrew (Sorex araneus), alpin
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hantaviruses rediscovery and new beginnings
Virus Research, 2014Co-Authors: Richard Yanagihara, Hae Ji Kang, Satoru Arai, Jin-won SongAbstract:Virus and host gene phylogenies, indicating that antigenically distinct hantaviruses (family Bunyaviridae, genus Hantavirus) segregate into clades, which parallel the molecular evolution of rodents belonging to the Murinae, Arvicolinae, Neotominae and Sigmodontinae subfamilies, suggested co-divergence of hantaviruses and their rodent reservoirs. Lately, this concept has been vigorously contested in favor of preferential host switching and local host-specific adaptation. To gain insights into the host range, spatial and temporal distribution, genetic diversity and evolutionary origins of hantaviruses, we employed reverse transcription-polymerase chain reaction to analyze frozen, RNAlater®-preserved and ethanol-fixed tissues from 1546 shrews (9 genera and 47 species), 281 moles (8 genera and 10 species) and 520 bats (26 genera and 53 species), collected in Europe, Asia, Africa and North America during 1980–2012. Thus far, we have identified 24 novel hantaviruses in shrews, moles and bats. That these newfound hantaviruses are geographically widespread and genetically more diverse than those harbored by rodents suggests that the evolutionary history of hantaviruses is far more complex than previously conjectured. Phylogenetic analyses indicate four distinct clades, with the most divergent comprising hantaviruses harbored by the European mole and insectivorous bats, with evidence for both co-divergence and host switching. Future studies will provide new knowledge about the transmission dynamics and pathogenic potential of these newly discovered, still-orphan, non-rodent-borne hantaviruses.
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characterization of imjin virus a newly isolated hantavirus from the ussuri white toothed shrew crocidura lasiura
Journal of Virology, 2009Co-Authors: Jin-won Song, Hae Ji Kang, Shannon N. Bennett, Sung Sil Moon, Kijoon Song, Luck Ju Baek, Heungchul Kim, Monica L Oguinn, Sungtae Chong, Terry A KleinAbstract:Until recently, the single known exception to the rodent-hantavirus association was Thottapalayam virus (TPMV), a long-unclassified virus isolated from the Asian house shrew (Suncus murinus). Robust gene amplification techniques have now uncovered several genetically distinct hantaviruses from shrews in widely separated geographic regions. Here, we report the characterization of a newly identified hantavirus, designated Imjin virus (MJNV), isolated from the lung tissues of Ussuri white-toothed shrews of the species Crocidura lasiura (order Soricomorpha, family Soricidae, subfamily Crocidurinae) captured near the demilitarized zone in the Republic of Korea during 2004 and 2005. Seasonal trapping revealed the highest prevalence of MJNV infection during the autumn, with evidence of infected shrews' clustering in distinct foci. Also, marked male predominance among anti-MJNV immunoglobulin G antibody-positive Ussuri shrews was found, whereas the male-to-female ratio among seronegative Ussuri shrews was near 1. Plaque reduction neutralization tests showed no cross neutralization for MJNV and rodent-borne hantaviruses but one-way cross neutralization for MJNV and TPMV. The nucleotide and deduced amino acid sequences for the different MJNV genomic segments revealed nearly the same calculated distances from hantaviruses harbored by rodents in the subfamilies Murinae, Arvicolinae, Neotominae, and Sigmodontinae. Phylogenetic analyses of full-length S, M, and L segment sequences demonstrated that MJNV shared a common ancestry with TPMV and remained in a distinct out-group, suggesting early evolutionary divergence. Studies are in progress to determine if MJNV is pathogenic for humans.
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seewis virus a genetically distinct hantavirus in the eurasian common shrew sorex araneus
Virology Journal, 2007Co-Authors: Jin-won Song, Satoru Arai, Shannon N. Bennett, M Puorger, Monika Hilbe, Richard YanagiharaAbstract:More than 20 years ago, hantaviral antigens were reported in tissues of the Eurasian common shrew (Sorex araneus), Eurasian water shrew (Neomys fodiens) and common mole (Talpa europea), suggesting that insectivores, or soricomorphs, might serve as reservoirs of unique hantaviruses. Using RT-PCR, sequences of a genetically distinct hantavirus, designated Seewis virus (SWSV), were amplified from lung tissue of a Eurasian common shrew, captured in October 2006 in Graubunden, Switzerland. Pair-wise analysis of the full-length S and partial M and L segments of SWSV indicated approximately 55%–72% similarity with hantaviruses harbored by Murinae, Arvicolinae, Neotominae and Sigmodontinae rodents. Phylogenetically, SWSV grouped with other recently identified shrew-borne hantaviruses. Intensified efforts are underway to clarify the genetic diversity of SWSV throughout the geographic range of the Eurasian common shrew, as well as to determine its relevance to human health.
Eric P Hoberg - One of the best experts on this subject based on the ideXlab platform.
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Broadening diversity in the Arostrilepis horrida complex: Arostrilepis kontrimavichusi n. sp. (Cyclophyllidea: Hymenolepididae) in the western red-backed vole Myodes californicus (Merriam) (Cricetidae: Arvicolinae) from temperate latitudes of the Pac
Systematic Parasitology, 2016Co-Authors: Arseny A. Makarikov, Eric P HobergAbstract:Specimens originally identified provisionally as Hymenolepis horrida (Linstow, 1901) [later Arostrilepis horrida (Linstow, 1901)] in Myodes californicus (Merriam) from near the Pacific coastal zone of southern Oregon are revised. Specimens in western red-backed voles represent an undescribed species of Arostrilepis Mas Coma & Tenora, 1997, contributing to recognition and resolution of a broadening complex encompassing cryptic diversity for these hymenolepidid tapeworms distributed across the Holarctic region. Consistent with recent studies defining diversity in the genus, the form, dimensions, and spination (pattern, shape and size) of the cirrus are diagnostic. Among 12 nominal congeners, specimens of A. kontrimavichusi n. sp. are further distinguished by the relative position and length of the cirrus-sac, arrangement of the testes and relative size of the external seminal vesicle and seminal receptacle. Specimens from Oregon voles represent the fifth endemic hymenolepidid in this genus from the Nearctic. Host range for the North American assemblage of species includes Cricetidae (Arvicolinae and Neotominae), Heteromyidae, Geomyidae, and rarely Sciuridae.
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hymenolepis folkertsi n sp eucestoda hymenolepididae in the oldfield mouse peromyscus polionotus wagner rodentia cricetidae Neotominae from the southeastern nearctic with comments on tapeworm faunal diversity among deer mice
Parasitology Research, 2015Co-Authors: Arseny A. Makarikov, Todd N. Nims, Kurt E Galbreath, Eric P HobergAbstract:A previously unrecognized species of hymenolepidid cestode attributable to Hymenolepis is de- scribed based on specimens in Peromyscus polionotus, oldfield mouse, from Georgia near the southeastern coast of continental North America. Specimens of Hymenolepis folkertsi n. sp. differ from those attributed to most other spe- cies in the genus by having testes arranged in a triangle and a scolex with a prominent rostrum-like protrusion. The newly recognized species is further distinguished by the relative po- sitionand length of the cirrus sac, shape of seminal receptacle, and relative size of external seminal vesicle and seminal re- ceptacle. Hymenolepidid cestodes have sporadically been re- ported among the highly diverse assemblage of Peromyscus which includes 56 distinct species in the Nearctic. Although the host genus has a great temporal duration and is endemic to the Nearctic, current evidence suggests that tapeworm faunal diversity reflects relatively recent assembly through bouts of host switching among other cricetid, murid, and geomyid ro- dents in sympatry.
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new species of arostrilepis eucestoda hymenolepididae in members of cricetidae and geomyidae rodentia from the western nearctic
Journal of Parasitology, 2012Co-Authors: Arseny A. Makarikov, Scott Lyell Gardner, Eric P HobergAbstract:Specimens originally identified as Arostrilepis horrida from the Nearctic are revised, contributing to the recognition of a complex of cryptic species distributed across the Holarctic region. Previously unrecognized species are described based on specimens in cricetid (Neotominae) and geomyid rodents. Arostrilepis mariettavogeae n. sp. in Peromyscus californicus from Monterey County, California and Arostrilepis schilleri n. sp. in Thomomys bulbivorus from Corvallis, Oregon are characterized. Consistent with recent studies defining diversity in the genus, form, size, and spination (pattern, shape, and size) of the cirrus are diagnostic; species are further distinguished by the relative position and length of the cirrus sac and arrangement of the testes. Species of Arostrilepis have not previously been described in rodents outside of the Arvicolinae or from localities in the Nearctic. These studies emphasize the need for routine deposition of archival specimens and information, from survey, ecological, and biogeographic studies, in museum collections to serve as self-correcting records for biodiversity at local, regional, and continental scales.
Elba Regina Sampaio De Lemos - One of the best experts on this subject based on the ideXlab platform.
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hantaviruses and a neglected environmental determinant
One Health, 2018Co-Authors: Alexandro Guterres, Elba Regina Sampaio De LemosAbstract:Most human pathogenic hantaviruses cause severe hemorrhagic fevers with a high rate of fatalities, such as occurs due to the genotypes causing hantavirus cardiopulmonary syndrome carried by the New World Sigmodontinae and Neotominae rodents. An increasing number of outbreaks and the possibility of cases spreading over international borders have led to greater interest in these viruses and the environmental determinants that facilitate their transmission. Rodents, shrews, moles and bats act as reservoir hosts of hantaviruses, and within the hantavirus transmission flow, the prevalence and distribution of infection in reservoir hosts is influenced by a range of factors. Climate change and landscape alteration affect hantavirus transmission, but the outcomes can differ among different hantaviruses and for the same virus in differentbiomes. However, it is evident that the underlying mechanisms that mediate hantavirus transmission are largely unknown, so that much work remains to be done regarding the transmission dynamics of hantaviruses. Overall, our review highlights the importance of examining interactions over several trophic levels and the underlying mechanisms (density and trait-mediated indirect effects) linking predation risk and hantavirus transmission, to develop an ecological framework to understand disease in natural, preserved and degraded systems.
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Hantaviruses and a neglected environmental determinant
Elsevier, 2018Co-Authors: Alexandro Guterres, Elba Regina Sampaio De LemosAbstract:Most human pathogenic hantaviruses cause severe hemorrhagic fevers with a high rate of fatalities, such as occurs due to the genotypes causing hantavirus cardiopulmonary syndrome carried by the New World Sigmodontinae and Neotominae rodents. An increasing number of outbreaks and the possibility of cases spreading over international borders have led to greater interest in these viruses and the environmental determinants that facilitate their transmission. Rodents, shrews, moles and bats act as reservoir hosts of hantaviruses, and within the hantavirus transmission flow, the prevalence and distribution of infection in reservoir hosts is influenced by a range of factors. Climate change and landscape alteration affect hantavirus transmission, but the outcomes can differ among different hantaviruses and for the same virus in differentbiomes. However, it is evident that the underlying mechanisms that mediate hantavirus transmission are largely unknown, so that much work remains to be done regarding the transmission dynamics of hantaviruses. Overall, our review highlights the importance of examining interactions over several trophic levels and the underlying mechanisms (density and trait-mediated indirect effects) linking predation risk and hantavirus transmission, to develop an ecological framework to understand disease in natural, preserved and degraded systems. Keywords: Hantavirus, Predation, Outbreak investigation, Environmental factor
Michael D Carleton - One of the best experts on this subject based on the ideXlab platform.
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chapter 5 a new species of reithrodontomys subgenus aporodon cricetidae Neotominae from the highlands of costa rica with comments on costa rican and panamanian reithrodontomys
Bulletin of the American Museum of Natural History, 2009Co-Authors: Alfred L Gardner, Michael D CarletonAbstract:Abstract A new species of the rodent genus Reithrodontomys (Cricetidae: Neotominae) is described from Cerro Asuncion in the western Cordillera de Talamanca, Costa Rica. The long tail, elongate rostrum, bulbous braincase, and complex molars of the new species associate it with members of the subgenus Aporodon, tenuirostris species group. In its diminutive size and aspects of cranial shape, the new species (Reithrodontomys musseri, sp. nov.) most closely resembles R. microdon, a form known from highlands in Guatemala and Chiapas, Mexico. In the course of differentially diagnosing the new species, we necessarily reviewed the Costa Rican and Panamanian subspecies of R. mexicanus based on morphological comparisons, study of paratypes and vouchers used in recent molecular studies, and morphometric analyses. We recognize Reithrodontomys cherrii (Allen, 1891) and R. garichensis Enders and Pearson, 1940, as valid species, and allocate R. mexicanus potrerograndei Goodwin, 1945, as a subjective synonym of R. breviro...
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a new species of habromys muroidea Neotominae from mexico with generic review of species definitions and remarks on diversity patterns among mesoamerican small mammals restricted to humid montane forests
Proceedings of the Biological Society of Washington, 2002Co-Authors: Michael D Carleton, Oscar Sanchez, Guillermina Urbano VidalesAbstract:A new species of Habromys, H. delicatulus, is described from an isolated patch of cloud forest situated on a northern exposure of the Cordillera Neovolcanica, Estado de Mexico. The species is the smallest so far known in the genus and is further characterized by its delicate cranial features. Morphometric comparisons with the five other species-group taxa currently allocated to the genus recommend the elevation of ixtlani Goodwin, 1964, as a species distinct from Habromys lepturus (Merriam, 1898). Habromys lophurus (Merriam, 1908), known from highlands east of the Isthmus of Tehuantepec, appears to be the sister taxon to the former pair, each restricted to separate Oaxacan ranges west of the Isthmus. Habromys chinanteco (Robertson & Musser, 1976) is retained as a species, but its possible status as a junior synonym under H. simulatus (Osgood, 1904) warrants continued investigation with improved samples. The montane distribution of Habromys in naturally discontinuous humid-forest associations of northern Mesoamerica is considered in the context of diversity patterns summarized for other small terrestrial mammals confined to such forests.