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Thomas Horn - One of the best experts on this subject based on the ideXlab platform.

  • Nonneoplastic disorders of the Eccrine glands
    Journal of The American Academy of Dermatology, 1998
    Co-Authors: Frederick G. Wenzel, Thomas Horn
    Abstract:

    Abstract Eccrine glands are uniquely susceptible to a variety of pathologic processes. Alteration in the rate of sweat secretion manifests as hypohidrosis and hyperhidrosis. Obstruction of the Eccrine duct leads to miliaria. The excretion of drugs into Eccrine sweat may be a contributory factor in Neutrophilic Eccrine Hidradenitis (NEH), syringosquamous metaplasia (SSM), coma bulla, and erythema multiforme (EM). Alterations in the electrolyte composition of Eccrine sweat can be observed in several systemic diseases, most notably cystic fibrosis. This article summarizes current knowledge of Eccrine gland pathophysiology. (J Am Acad Dermatol 1998;38:1-17.)

  • Nonneoplastic disorders of the Eccrine glands
    Journal of The American Academy of Dermatology, 1998
    Co-Authors: Frederick G. Wenzel, Thomas Horn
    Abstract:

    Abstract Eccrine glands are uniquely susceptible to a variety of pathologic processes. Alteration in the rate of sweat secretion manifests as hypohidrosis and hyperhidrosis. Obstruction of the Eccrine duct leads to miliaria. The excretion of drugs into Eccrine sweat may be a contributory factor in Neutrophilic Eccrine Hidradenitis (NEH), syringosquamous metaplasia (SSM), coma bulla, and erythema multiforme (EM). Alterations in the electrolyte composition of Eccrine sweat can be observed in several systemic diseases, most notably cystic fibrosis. This article summarizes current knowledge of Eccrine gland pathophysiology. (J Am Acad Dermatol 1998;38:1-17.)

  • Nonneoplastic disorders of the Eccrine glands
    Journal of the American Academy of Dermatology, 1998
    Co-Authors: Frederick G. Wenzel, Thomas Horn
    Abstract:

    Eccrine glands are uniquely susceptible to a variety of pathologic processes. Alteration in the rate of sweat secretion manifests as hypohidrosis and hyperhidrosis. Obstruction of the Eccrine duct leads to miliaria. The excretion of drugs into Eccrine sweat may be a contributory factor in Neutrophilic Eccrine Hidradenitis (NEH), syringosquamous metaplasia (SSM), coma bulla, and erythema multiforme (EM). Alterations in the electrolyte composition of Eccrine sweat can be observed in several systemic diseases, most notably cystic fibrosis. This article summarizes current knowledge of Eccrine gland pathophysiology.

Selim Aractingi - One of the best experts on this subject based on the ideXlab platform.

  • Recurrent Neutrophilic Eccrine Hidradenitis in an HIV-1-Infected Patient
    Dermatology (Basel Switzerland), 2000
    Co-Authors: C. Bachmeyer, P. Reygagne, Selim Aractingi
    Abstract:

    Most cases of Neutrophilic Eccrine Hidradenitis (NEH) have been reported in patients receiving chemotherapy for acute myelogenous leukemia or other malignant diseases. We report the case of an HIV-1-i

  • Neutrophilic Eccrine Hidradenitis.
    Clinics in dermatology, 2000
    Co-Authors: C. Bachmeyer, Selim Aractingi
    Abstract:

    Neutrophilic Eccrine Hidradenitis (NEH) is a recently described disease characterized by the presence of a cutaneous aseptic infiltrate of polymorphonuclear neutrophils, whose peculiar feature is linked to the elective disposition of the infiltrate around Eccrine coils and glands. This condition has been initially and until now mainly reported in patients receiving chemotherapy regimens for acute myelogenous leukemia (AML), leading some investigators to hypothesize that NEH could represent a peculiar reaction to cytotoxic drugs excreted in sweat. The description of cases occurring before the diagnosis of the hemopathy, of cases in individuals treated with granulocyte colony-stimulating factor (G-CSF) or even of patients with other malignancies, suggests that NEH may rather be— closely to Sweet’s syndrome—a part of the spectrum of Neutrophilic diseases. To the best of our knowledge, 51 cases of NEH have been reported in the literature to date. Clinical and histological features of these cases are reviewed and pathogenesis is discussed.

  • Neutrophilic Eccrine Hidradenitis associated with relapse of acute myeloblastic leukemia
    Annales de dermatologie et de venereologie, 1998
    Co-Authors: Saada, Selim Aractingi, Leblond, Eduardo Marinho, Camille Francès, Olivier Chosidow
    Abstract:

    Introduction. L'hidradenite Eccrine neutrophilique est une entite de description recente. La plupart des cas rapportes sont survenus au decours d'un traitement par chimiotherapie pour leucemie aigue myeloblastique. laissant penser que cette maladie pouvait etre induite par les medicaments. Neanmoins, d'autres auteurs considerent que l'hidradenite Eccrine neutrophilique appartient au groupe des dermatoses neutroptiliques. Observation. Nous rapportons le cas d'un homme de 48 ans chez qui des lesions d'hidradenite Eccrine neutrophilique sont survenues de maniere contemporaine a une rechute de leucemie aigue, sans qu'il n'y ait eu aucune chimiotherapie durant les mois precedents. Discussion. Cette observation renforce l'hypothese que l'hidradenite Eccrine neutrophilique est une dermatose associee aux hemopathies myeloides et non pas une complication des therapeutiques.

  • Neutrophilic dermatoses during granulocytopenia.
    Archives of dermatology, 1995
    Co-Authors: Selim Aractingi, Olivier Chosidow, Valérie Mallet, L Pinquier, M.-d. Vignon-pennamen, Laurent Degos, Louis Dubertret, Hervé Dombret
    Abstract:

    Background and Design: Noninfectious cutaneous Neutrophilic lesions can occur during granulocytopenia, but their mechanism remains unknown. We undertook a retrospective study of the Neutrophilic dermatoses that developed during granulocytopenia induced by chemotherapy for acute myelogenous leukemia. Results: Seven men and one woman were included (2.6% of treated cases of acute myelogenous leukemia); half had acute myelogenous leukemia subtypes 4 and 5. The male-to-female ratio was 7:1. Neutrophilic Eccrine Hidradenitis was diagnosed in five cases, Sweet's syndrome in two cases, and difficult-to-classify Neutrophilic dermatoses in one case. Cutaneous lesions appeared 12.5 days after the start of chemotherapy, and the mean leukocyte count was 0.426× 109/L. Three patients needed corticosteroids systemically. Conclusion: Neutrophilic dermatoses during chemotherapy-induced granulocytopenia seem to occur more frequently in men with acute myelogenous leukemia subtypes 4 and 5. (Arch Dermatol. 1995;131:1141-1145)

Frederick G. Wenzel - One of the best experts on this subject based on the ideXlab platform.

  • Nonneoplastic disorders of the Eccrine glands
    Journal of The American Academy of Dermatology, 1998
    Co-Authors: Frederick G. Wenzel, Thomas Horn
    Abstract:

    Abstract Eccrine glands are uniquely susceptible to a variety of pathologic processes. Alteration in the rate of sweat secretion manifests as hypohidrosis and hyperhidrosis. Obstruction of the Eccrine duct leads to miliaria. The excretion of drugs into Eccrine sweat may be a contributory factor in Neutrophilic Eccrine Hidradenitis (NEH), syringosquamous metaplasia (SSM), coma bulla, and erythema multiforme (EM). Alterations in the electrolyte composition of Eccrine sweat can be observed in several systemic diseases, most notably cystic fibrosis. This article summarizes current knowledge of Eccrine gland pathophysiology. (J Am Acad Dermatol 1998;38:1-17.)

  • Nonneoplastic disorders of the Eccrine glands
    Journal of The American Academy of Dermatology, 1998
    Co-Authors: Frederick G. Wenzel, Thomas Horn
    Abstract:

    Abstract Eccrine glands are uniquely susceptible to a variety of pathologic processes. Alteration in the rate of sweat secretion manifests as hypohidrosis and hyperhidrosis. Obstruction of the Eccrine duct leads to miliaria. The excretion of drugs into Eccrine sweat may be a contributory factor in Neutrophilic Eccrine Hidradenitis (NEH), syringosquamous metaplasia (SSM), coma bulla, and erythema multiforme (EM). Alterations in the electrolyte composition of Eccrine sweat can be observed in several systemic diseases, most notably cystic fibrosis. This article summarizes current knowledge of Eccrine gland pathophysiology. (J Am Acad Dermatol 1998;38:1-17.)

  • Nonneoplastic disorders of the Eccrine glands
    Journal of the American Academy of Dermatology, 1998
    Co-Authors: Frederick G. Wenzel, Thomas Horn
    Abstract:

    Eccrine glands are uniquely susceptible to a variety of pathologic processes. Alteration in the rate of sweat secretion manifests as hypohidrosis and hyperhidrosis. Obstruction of the Eccrine duct leads to miliaria. The excretion of drugs into Eccrine sweat may be a contributory factor in Neutrophilic Eccrine Hidradenitis (NEH), syringosquamous metaplasia (SSM), coma bulla, and erythema multiforme (EM). Alterations in the electrolyte composition of Eccrine sweat can be observed in several systemic diseases, most notably cystic fibrosis. This article summarizes current knowledge of Eccrine gland pathophysiology.

Ralph J. Tuthill - One of the best experts on this subject based on the ideXlab platform.

  • Neutrophilic Eccrine Hidradenitis Heralding the Onset of Acute Myelogenous Leukemia
    Archives of dermatology, 1993
    Co-Authors: Joseph C. Pierson, Thomas N. Helm, James S. Taylor, Dirk M. Elston, Ralph J. Tuthill
    Abstract:

    To the Editor.— Neutrophilic Eccrine Hidradenitis (NEH) was originally described as a distinctive dermatosis that occurred in patients undergoing chemotherapy for acute myelogenous leukemia (AML). 1,2 Although NEH has since been reported in several other settings, 3-6 most theories regarding its pathogenesis have focused on the role of the implicated therapeutic agents. We report the first case of NEH arising several weeks prior to the onset of fulminant AML. This suggests that NEH may be a paraneoplastic phenomenon, as was proposed in the initial reports on this entity. 1,2 Report of a Case.— A 44-year-old woman had a 2-month history of a nonpruritic rash that she associated with an insect bite reaction. Fever, arthralgias, decreased appetite, and weight loss developed several weeks later. Acetaminophen failed to control her symptoms. A course of methylprednisolone and erythromycin led to resolution of the rash and systemic symptoms, only to recur 1 week later.

Nancy B. Esterly - One of the best experts on this subject based on the ideXlab platform.

  • Recurrent palmoplantar Hidradenitis in children.
    Archives of dermatology, 1995
    Co-Authors: Linda G. Rabinowitz, Maria Letícia Cintra, Antoinette F. Hood, Nancy B. Esterly
    Abstract:

    Background: There are several reports of tender, erythematous plantar nodules occurring in pediatric patients. Despite similar morphological features, the histologic findings in these lesions have been quite diverse. A new entity calledidiopathic plantar Hidradenitis(also termedNeutrophilic Eccrine Hidradenitis in children), which is characterized by tender, red nodules on the feet and unique histopathologic features, was recently described. Observations: We describe two children with these unusual cutaneous lesions and histopathologic findings and compare them with patients with idiopathic plantar Hidradenitis. Our patients, in contrast to those with idiopathic plantar Hidradenitis, had involvement of the palms as well as the soles. Both children had self-limited recurrent lesions; in one child, the lesions were associated with low-grade fever. Biopsy specimen findings in both cases demonstrated dense Neutrophilic infiltrates localized to the Eccrine units. Conclusions: Our patients had clinical and histologic findings similar to those recently reported as idiopathic plantar Hidradenitis (Neutrophilic Eccrine Hidradenitis in children). Because palms and soles can be affected and the lesions typically recur, we suggest that this condition be referred to asrecurrent palmoplantar Hidradenitis. (Arch Dermatol. 1995;131:817-820)