The Experts below are selected from a list of 282 Experts worldwide ranked by ideXlab platform

Claudio Gobbi - One of the best experts on this subject based on the ideXlab platform.

  • Recurrent Nicolau Syndrome associated with subcutaneous glatiramer acetate injection—a case report
    BMC Neurology, 2015
    Co-Authors: Chiara Zecca, Carlo Mainetti, Roland Blum, Claudio Gobbi
    Abstract:

    Background Glatiramer acetate is worldwide used as first line treatment in relapsing remitting multiple sclerosis. Local skin reactions associated with glatiramer acetate are common, however, only isolated cases of severe local injection site reactions known as Nicolau Syndrome have been reported so far. Case presentation We describe the case of a recurrent Nicolau Syndrome occurred during longstanding glatiramer acetate treatment in a woman with multiple sclerosis. The haemorrhagic patch necrotized and was treated locally as a deep second degree burn with excision of dead skin tissue and was healed. Treatment with glatiramer acetate was definitely suspended. Conclusions GA injections can be complicated by isolated or recurrent Nicolau Syndrome, a potentially life-threatening condition of which neurologists should be aware.

  • recurrent Nicolau Syndrome associated with subcutaneous glatiramer acetate injection a case report
    BMC Neurology, 2015
    Co-Authors: Chiara Zecca, Carlo Mainetti, Roland Blum, Claudio Gobbi
    Abstract:

    Background Glatiramer acetate is worldwide used as first line treatment in relapsing remitting multiple sclerosis. Local skin reactions associated with glatiramer acetate are common, however, only isolated cases of severe local injection site reactions known as Nicolau Syndrome have been reported so far.

Chiara Zecca - One of the best experts on this subject based on the ideXlab platform.

  • Recurrent Nicolau Syndrome associated with subcutaneous glatiramer acetate injection—a case report
    BMC Neurology, 2015
    Co-Authors: Chiara Zecca, Carlo Mainetti, Roland Blum, Claudio Gobbi
    Abstract:

    Background Glatiramer acetate is worldwide used as first line treatment in relapsing remitting multiple sclerosis. Local skin reactions associated with glatiramer acetate are common, however, only isolated cases of severe local injection site reactions known as Nicolau Syndrome have been reported so far. Case presentation We describe the case of a recurrent Nicolau Syndrome occurred during longstanding glatiramer acetate treatment in a woman with multiple sclerosis. The haemorrhagic patch necrotized and was treated locally as a deep second degree burn with excision of dead skin tissue and was healed. Treatment with glatiramer acetate was definitely suspended. Conclusions GA injections can be complicated by isolated or recurrent Nicolau Syndrome, a potentially life-threatening condition of which neurologists should be aware.

  • recurrent Nicolau Syndrome associated with subcutaneous glatiramer acetate injection a case report
    BMC Neurology, 2015
    Co-Authors: Chiara Zecca, Carlo Mainetti, Roland Blum, Claudio Gobbi
    Abstract:

    Background Glatiramer acetate is worldwide used as first line treatment in relapsing remitting multiple sclerosis. Local skin reactions associated with glatiramer acetate are common, however, only isolated cases of severe local injection site reactions known as Nicolau Syndrome have been reported so far.

Roland Blum - One of the best experts on this subject based on the ideXlab platform.

  • Recurrent Nicolau Syndrome associated with subcutaneous glatiramer acetate injection—a case report
    BMC Neurology, 2015
    Co-Authors: Chiara Zecca, Carlo Mainetti, Roland Blum, Claudio Gobbi
    Abstract:

    Background Glatiramer acetate is worldwide used as first line treatment in relapsing remitting multiple sclerosis. Local skin reactions associated with glatiramer acetate are common, however, only isolated cases of severe local injection site reactions known as Nicolau Syndrome have been reported so far. Case presentation We describe the case of a recurrent Nicolau Syndrome occurred during longstanding glatiramer acetate treatment in a woman with multiple sclerosis. The haemorrhagic patch necrotized and was treated locally as a deep second degree burn with excision of dead skin tissue and was healed. Treatment with glatiramer acetate was definitely suspended. Conclusions GA injections can be complicated by isolated or recurrent Nicolau Syndrome, a potentially life-threatening condition of which neurologists should be aware.

  • recurrent Nicolau Syndrome associated with subcutaneous glatiramer acetate injection a case report
    BMC Neurology, 2015
    Co-Authors: Chiara Zecca, Carlo Mainetti, Roland Blum, Claudio Gobbi
    Abstract:

    Background Glatiramer acetate is worldwide used as first line treatment in relapsing remitting multiple sclerosis. Local skin reactions associated with glatiramer acetate are common, however, only isolated cases of severe local injection site reactions known as Nicolau Syndrome have been reported so far.

Carlo Mainetti - One of the best experts on this subject based on the ideXlab platform.

  • Recurrent Nicolau Syndrome associated with subcutaneous glatiramer acetate injection—a case report
    BMC Neurology, 2015
    Co-Authors: Chiara Zecca, Carlo Mainetti, Roland Blum, Claudio Gobbi
    Abstract:

    Background Glatiramer acetate is worldwide used as first line treatment in relapsing remitting multiple sclerosis. Local skin reactions associated with glatiramer acetate are common, however, only isolated cases of severe local injection site reactions known as Nicolau Syndrome have been reported so far. Case presentation We describe the case of a recurrent Nicolau Syndrome occurred during longstanding glatiramer acetate treatment in a woman with multiple sclerosis. The haemorrhagic patch necrotized and was treated locally as a deep second degree burn with excision of dead skin tissue and was healed. Treatment with glatiramer acetate was definitely suspended. Conclusions GA injections can be complicated by isolated or recurrent Nicolau Syndrome, a potentially life-threatening condition of which neurologists should be aware.

  • recurrent Nicolau Syndrome associated with subcutaneous glatiramer acetate injection a case report
    BMC Neurology, 2015
    Co-Authors: Chiara Zecca, Carlo Mainetti, Roland Blum, Claudio Gobbi
    Abstract:

    Background Glatiramer acetate is worldwide used as first line treatment in relapsing remitting multiple sclerosis. Local skin reactions associated with glatiramer acetate are common, however, only isolated cases of severe local injection site reactions known as Nicolau Syndrome have been reported so far.

Scott D Newsome - One of the best experts on this subject based on the ideXlab platform.

  • case report two cases of Nicolau Syndrome associated with glatiramer acetate
    International journal of MS care, 2017
    Co-Authors: Dorlan Kimbrough, Scott D Newsome
    Abstract:

    We report two cases of Nicolau Syndrome (embolia cutis medicamentosa), a rare complication of injectable medications, both associated with the administration of 20 mg of subcutaneous glatiramer acetate. Both patients required surgical debridement and were subsequently treated conservatively without additional complications. Patient 1 opted to discontinue disease-modifying therapy. Patient 2 continued glatiramer acetate therapy without complications by using other injection sites. These cases highlight the need for prompt investigation of new unusual skin lesions in patients receiving injectable multiple sclerosis treatments (regardless of length of treatment and previous minor cosmetic concerns) and illustrate the clinical distinction between Nicolau Syndrome and drug-induced skin necrosis.