The Experts below are selected from a list of 105 Experts worldwide ranked by ideXlab platform
Gary Brooker - One of the best experts on this subject based on the ideXlab platform.
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cinch confocal incoherent correlation holography super resolution fluorescence microscopy based upon finch fresnel incoherent correlation holography
Proceedings of SPIE, 2015Co-Authors: Nisan Siegel, Marc A Bruce, Brian Storrie, Gary BrookerAbstract:FINCH holographic fluorescence microscopy creates high resolution super-resolved images with enhanced depth of focus. The simple addition of a real-time Nipkow Disk confocal image scanner in a conjugate plane of this incoherent holographic system is shown to reduce the depth of focus, and the combination of both techniques provides a simple way to enhance the axial resolution of FINCH in a combined method called "CINCH". An important feature of the combined system allows for the simultaneous real-time image capture of widefield and holographic images or confocal and confocal holographic images for ready comparison of each method on the exact same field of view. Additional GPU based complex deconvolution processing of the images further enhances resolution.
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improved axial resolution of finch fluorescence microscopy when combined with spinning Disk confocal microscopy
Optics Express, 2014Co-Authors: Nisan Siegel, Gary BrookerAbstract:FINCH holographic fluorescence microscopy creates super-resolved images with enhanced depth of focus. Addition of a Nipkow Disk real-time confocal image scanner is shown to reduce the FINCH depth of focus while improving transverse confocal resolution in a combined method called “CINCH”.
D R S Cumming - One of the best experts on this subject based on the ideXlab platform.
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a Nipkow Disk integrated with fresnel lenses for terahertz single pixel imaging
Optics Express, 2013Co-Authors: James Grant, Jue Wang, D R S CummingAbstract:We present a novel Nipkow Disk design for terahertz (THz) single pixel imaging applications. A 100 mm high resistivity (ρ≈3k-10k Ω·cm) silicon wafer was used for the Disk on which a spiral array of twelve 16-level binary Fresnel lenses were fabricated using photolithography and a dry-etch process. The implementation of Fresnel lenses on the Nipkow Disk increases the THz signal transmission compared to the conventional pinhole-based Nipkow Disk by more than 12 times thus a THz source with lower power or a THz detector with lower detectivity can be used. Due to the focusing capability of the lenses, a pixel resolution better than 0.5 mm is in principle achievable. To demonstrate the concept, a single pixel imaging system operating at 2.52 THz is described.
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terahertz single pixel imaging based on a Nipkow Disk
Optics Letters, 2012Co-Authors: James Grant, Shimul Chandra Saha, D R S CummingAbstract:We describe a terahertz single pixel imaging system based on a Nipkow Disk. Nipkow Disks have been used for fast scanning imaging systems since the first experimental television was invented in 1926. In our work, a Nipkow Disk with 24 scanning lines was used to provide an axial resolution of 2 mm/pixel. We also show that by implementing a microscanning technique the axial resolution can be further improved to 0.5 mm/pixel. Imaging of several objects was demonstrated to show that this simple scanning system is promising for fast or real time terahertz imaging applications.
Nisan Siegel - One of the best experts on this subject based on the ideXlab platform.
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cinch confocal incoherent correlation holography super resolution fluorescence microscopy based upon finch fresnel incoherent correlation holography
Proceedings of SPIE, 2015Co-Authors: Nisan Siegel, Marc A Bruce, Brian Storrie, Gary BrookerAbstract:FINCH holographic fluorescence microscopy creates high resolution super-resolved images with enhanced depth of focus. The simple addition of a real-time Nipkow Disk confocal image scanner in a conjugate plane of this incoherent holographic system is shown to reduce the depth of focus, and the combination of both techniques provides a simple way to enhance the axial resolution of FINCH in a combined method called "CINCH". An important feature of the combined system allows for the simultaneous real-time image capture of widefield and holographic images or confocal and confocal holographic images for ready comparison of each method on the exact same field of view. Additional GPU based complex deconvolution processing of the images further enhances resolution.
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improved axial resolution of finch fluorescence microscopy when combined with spinning Disk confocal microscopy
Optics Express, 2014Co-Authors: Nisan Siegel, Gary BrookerAbstract:FINCH holographic fluorescence microscopy creates super-resolved images with enhanced depth of focus. Addition of a Nipkow Disk real-time confocal image scanner is shown to reduce the FINCH depth of focus while improving transverse confocal resolution in a combined method called “CINCH”.
James Grant - One of the best experts on this subject based on the ideXlab platform.
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a Nipkow Disk integrated with fresnel lenses for terahertz single pixel imaging
Optics Express, 2013Co-Authors: James Grant, Jue Wang, D R S CummingAbstract:We present a novel Nipkow Disk design for terahertz (THz) single pixel imaging applications. A 100 mm high resistivity (ρ≈3k-10k Ω·cm) silicon wafer was used for the Disk on which a spiral array of twelve 16-level binary Fresnel lenses were fabricated using photolithography and a dry-etch process. The implementation of Fresnel lenses on the Nipkow Disk increases the THz signal transmission compared to the conventional pinhole-based Nipkow Disk by more than 12 times thus a THz source with lower power or a THz detector with lower detectivity can be used. Due to the focusing capability of the lenses, a pixel resolution better than 0.5 mm is in principle achievable. To demonstrate the concept, a single pixel imaging system operating at 2.52 THz is described.
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terahertz single pixel imaging based on a Nipkow Disk
Optics Letters, 2012Co-Authors: James Grant, Shimul Chandra Saha, D R S CummingAbstract:We describe a terahertz single pixel imaging system based on a Nipkow Disk. Nipkow Disks have been used for fast scanning imaging systems since the first experimental television was invented in 1926. In our work, a Nipkow Disk with 24 scanning lines was used to provide an axial resolution of 2 mm/pixel. We also show that by implementing a microscanning technique the axial resolution can be further improved to 0.5 mm/pixel. Imaging of several objects was demonstrated to show that this simple scanning system is promising for fast or real time terahertz imaging applications.
Stefan W Hell - One of the best experts on this subject based on the ideXlab platform.
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comparison of the axial resolution of practical Nipkow Disk confocal fluorescence microscopy with that of multifocal multiphoton microscopy theory and experiment
Journal of Microscopy, 2002Co-Authors: Alexander Egner, V Andresen, Stefan W HellAbstract:Summary We compare the axial sectioning capability of multifocal confocal and multifocal multiphoton microscopy in theory and in experiment, with particular emphasis on the background arising from the cross-talk between adjacent imaging channels. We demonstrate that a time-multiplexed non-linear excitation microscope exhibits significantly less background and therefore a superior axial resolution as compared to a multifocal single-photon confocal system. The background becomes irrelevant for thin (< 15 µm) and sparse fluorescent samples, in which case the confocal parallelized system exhibits similar or slightly better sectioning behaviour due to its shorter excitation wavelength. Theoretical and experimental axial responses of practically implemented microscopes are given.