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Alexander K. C. Leung - One of the best experts on this subject based on the ideXlab platform.

  • primary and secondary Nocturnal Enuresis similarities in presentation
    Pediatrics, 2005
    Co-Authors: Wm Lane M Robson, Alexander K. C. Leung, Robert S Van Howe
    Abstract:

    Objective To determine the differences or similarities in the clinical presentation between patients with primary and secondary Nocturnal Enuresis. Methods A total of 170 patients with Nocturnal Enuresis were assessed at a busy tertiary care pediatric voiding dysfunction clinic at the University of Oklahoma Health Sciences Center. Patients with primary Nocturnal Enuresis (PNE) were compared with patients with secondary Nocturnal Enuresis (SNE) for a variety of clinical features, including gender, age when first voiding on their own, age on presentation, infrequent voiding, frequent voiding, urgency, daytime wetting, nocturia, urinary tract infection, constipation, vesicoureteral reflux, attention-deficit/hyperactivity disorder, uroflow results, and ultrasound evidence of a postvoid residual. Results The only significant difference between the patients with PNE and those with SNE was in the prevalence of constipation. Constipation was significantly associated with PNE (74.59% vs 57.54%; odds ratio: 2.17; 95% confidence interval: 1.07-4.41). When adjusted for a history of constipation, the age at which a child began to void on his or her own became statistically significant. Patients with SNE started to void on their own at 2.13 years (SD: 0.61), an average of 0.22 years earlier than those with PNE, who started to void on their own at 2.35 years. Conclusions PNE and SNE likely share a common pathogenesis. Symptoms of daytime voiding dysfunction are common in patients with PNE and SNE. Daytime voiding habits might influence how the central nervous system responds at night to a full or contracting bladder.

  • Secondary Nocturnal Enuresis
    Clinical pediatrics, 2000
    Co-Authors: Lane M. Robson, Alexander K. C. Leung
    Abstract:

    Secondary Nocturnal Enuresis accounts for about one quarter of patients with bed-wetting. Although a psychological cause is responsible in some children, various other causes are possible and should be considered. This article reviews the epidemiology, psychological and social impact, causes, investigation, management, and prognosis of secondary Nocturnal Enuresis.

  • Hyponatremia in Patients With Nocturnal Enuresis Treated With DDAVP
    Journal of Urology, 1998
    Co-Authors: William Lane M. Robson, J. P. Nørgaard, Alexander K. C. Leung
    Abstract:

    Treatment of Nocturnal Enuresis with DDAVP is associated with a low incidence of adverse effects. The only reported serious adverse effect is seizure or altered level of consciousness due to water intoxication. We reviewed 14 articles that reported data on serum sodium in patients treated with DDAVP for Nocturnal Enuresis and 11 articles that reported patients who developed a seizure or altered level of consciousness during treatment with DDAVP for Nocturnal Enuresis. Excess fluid intake was identified as a contributing factor in 6 of the 11 case reports.

  • Hyponatremia in patients with Nocturnal Enuresis treated with DDAVP.
    European journal of pediatrics, 1996
    Co-Authors: William Lane M. Robson, J. P. Nørgaard, Alexander K. C. Leung
    Abstract:

    UNLABELLED Treatment of Nocturnal Enuresis with DDAVP is associated with a low incidence of adverse effects. The only reported serious adverse effect is seizure or altered level of consciousness due to water intoxication. We reviewed 14 articles that reported data on serum sodium in patients treated with DDAVP for Nocturnal Enuresis and 11 articles that reported patients who developed a seizure or altered level of consciousness during treatment with DDAVP for Nocturnal Enuresis. Excess fluid intake was identified as a contributing factor in 6 of the 11 case reports. CONCLUSION Hyponatremia is a potential adverse effect in patients with Nocturnal Enuresis who are treated with DDAVP. To prevent this adverse effect we recommend that the patients prescribed DDAVP for Nocturnal Enuresis should be counseled not to ingest more than 240 ml (8 ounces) of fluid on any night that DDAVP is administered.

Patrina H. Y. Caldwell - One of the best experts on this subject based on the ideXlab platform.

  • Management of Nocturnal Enuresis
    BMJ (Clinical research ed.), 2013
    Co-Authors: Patrina H. Y. Caldwell, Aniruddh V. Deshpande, Alexander Von Gontard
    Abstract:

    #### Summary points #### Sources and selection criteria We searched Medline, Embase, and the Cochrane Database of Systematic Reviews using the search terms “Enuresis” or “bedwetting” as keywords. Systematic reviews, meta-analyses, population based studies, randomised controlled trials, and studies published in the past five years were prioritised. Nocturnal Enuresis (Enuresis or bedwetting) is the most common type of urinary incontinence in children. Depending on the definition, prevalence is 8-20% for 5 year olds, 1.5-10% for 10 year olds, and 0.5-2% for adults, with 2.6% of 7.5 year old children wetting on two or more nights a week.1 Prevalence seems to be similar worldwide. Here, we review current knowledge about the treatment of this common condition. Nocturnal Enuresis is intermittent involuntary voiding during sleep in the absence of physical disease in a child aged 5 years or more. A minimum of one episode a month for at least three months is required for the diagnosis to be made.2 A large epidemiological study showed that Nocturnal Enuresis is more common in males at all ages, and is more likely to persist in those with frequent wetting.3 Nocturnal Enuresis is usually idiopathic and is commonly associated with daytime urinary incontinence (seen in 3.3% of 7.5 year olds in a large epidemiological study1), faecal incontinence, and chronic constipation. In …

  • Medical Management of Nocturnal Enuresis
    Pediatric Drugs, 2012
    Co-Authors: Aniruddh V. Deshpande, Patrina H. Y. Caldwell
    Abstract:

    Nocturnal Enuresis, or bedwetting, is the most common cause of urinary incontinence in children. It is known to have a significant psychosocial impact on the child as well as the family. Nocturnal Enuresis typically presents as failure to become dry at night after successful daytime toilet training. It can be primary or secondary (developing after being successfully dry at night for at least 6 months). Children with Nocturnal Enuresis may have excessive Nocturnal urine production, poor sleep arousal and/or reduced bladder capacity. Alarm therapy is the recommended first-line therapy, with treatment choices being influenced by the presence or absence of the abnormalities mentioned above. Children with Nocturnal Enuresis may also have daytime urinary urgency, frequency or incontinence of urine. This group (non-monosymptomatic Nocturnal Enuresis) requires a different clinical approach, with a focus on treating daytime bladder symptoms, which commonly involves pharmacotherapy with anti-cholinergic medications and urotherapy (including addressing bowel problems). This review discusses the current management of Nocturnal Enuresis using the terminologies recommended by the International Children’s Continence Society.

  • Medical management of Nocturnal Enuresis.
    Paediatric drugs, 2012
    Co-Authors: Aniruddh V. Deshpande, Patrina H. Y. Caldwell
    Abstract:

    Nocturnal Enuresis, or bedwetting, is the most common cause of urinary incontinence in children. It is known to have a significant psychosocial impact on the child as well as the family.

  • Risk Factors for Nocturnal Enuresis in School-Age Children
    The Journal of urology, 2009
    Co-Authors: Premala Sureshkumar, Patrina H. Y. Caldwell, Michael P. Jones, Jonathan C. Craig
    Abstract:

    Purpose: Although Nocturnal Enuresis is common in children, its etiology is multifactorial and not fully understood. We evaluated potential risk factors for presence and severity of Nocturnal Enuresis.Materials and Methods: A validated, reproducible questionnaire was distributed to 8,230 school children in Sydney, Australia. Nocturnal Enuresis was defined as any wetting in the previous month and categorized as mild (1 to 6 nights), moderate (7 or more nights but less than nightly) or severe (nightly).Results: Parents of 2,856 children (mean ± SD age 7.3 ± 1.3 years) completed the questionnaire (response rate 35%). Overall prevalence of Nocturnal Enuresis was 18.2%, with 12.3% of patients having mild, 2.5% moderate and 3.6% severe Enuresis. Multivariate analysis showed that daytime incontinence (OR 4.8, 95% CI 2.9 to 7.9), encopresis (OR 2.7, 95% CI 1.6 to 4.4), bladder dysfunction (OR 3.6, 95% CI 2.4 to 5.3) and male gender (OR 2.0, 95% CI 1.3 to 3.1) were associated with severe Nocturnal Enuresis after a...

Kwaku Ohene-frempong - One of the best experts on this subject based on the ideXlab platform.

  • Nocturnal Enuresis in pediatric sickle cell disease
    Journal of developmental and behavioral pediatrics : JDBP, 2001
    Co-Authors: Lamia P. Barakat, Kim Smith-whitley, Seth Schulman, Daniel Rosenberg, Rupa Puri, Kwaku Ohene-frempong
    Abstract:

    To assess the prevalence of Nocturnal Enuresis in children and adolescents with sickle cell disease (SCD) and associated factors, structured telephone interviews were conducted with primary caregivers of 217 children and adolescents with SCD aged 5 years or older. Prevalence, perceived causes, interventions undertaken, and emotional impact were assessed. Nocturnal Enuresis was significantly higher for males (28.2% of males) than for females (11% of females), p = .002, and compared with cited population prevalence rates, Nocturnal Enuresis was significantly higher for children with SCD, p < .01. SCD was the most common reason given by primary caregivers for Enuresis. Primary caregivers used a wide range of interventions for Nocturnal Enuresis, but few used empirically supported treatments for Enuresis or spoke with their health care team about the Enuresis. These data suggest that systematic assessment and intervention for Nocturnal Enuresis must be implemented in the follow-up care of children and adolescents with SCD.

Kuang-hung Hsu - One of the best experts on this subject based on the ideXlab platform.

  • Prevalence of Nocturnal Enuresis and Associated Familial Factors in Primary School Children in Taiwan
    The Journal of urology, 2002
    Co-Authors: Tsang-wee Cher, Ghi-jen Lin, Kuang-hung Hsu
    Abstract:

    ABSTRACTPurpose: We investigated the prevalence and associated factors of Nocturnal Enuresis in children in elementary schools in Taiwan.Materials and Methods: A cross-sectional study of Nocturnal Enuresis in Taiwanese school children was performed in 10 primary schools in Tao-Yuan County, Taiwan. Questionnaires on demographic data, familial and physical conditions were completed by 7,225 children assisted by their parents.Results: The overall prevalence of Nocturnal Enuresis in Taiwanese primary school children was 5.5%. Decreasing age, male gender, family size, birth rank, parental education level and parental raising style were possible familial risk factors for Nocturnal Enuresis in this study.Conclusions: The study indicates a prevalence of Nocturnal Enuresis in the Taiwanese population comparable to that in western populations, showing that Nocturnal Enuresis is an international problem that should be considered seriously. Findings of familial factors associated with Nocturnal Enuresis provide a clu...

Michael R. Debaun - One of the best experts on this subject based on the ideXlab platform.

  • Nocturnal Enuresis in sickle cell disease
    Expert review of hematology, 2014
    Co-Authors: Rachel B. Wolf, Adetola A. Kassim, Robert L Goodpaster, Michael R. Debaun
    Abstract:

    Nocturnal Enuresis is a prevalent and challenging problem in children and young adults with sickle cell disease (SCD). Limited progress has been made in elucidating etiology and pathophysiology of Nocturnal Enuresis in individuals with SCD. Among adults with SCD ages 18–20 years, approximately 9% report Nocturnal Enuresis. Nocturnal Enuresis contributes to decreased health related quality of life in people with SCD, resulting in low self-esteem and sometimes social isolation. Postulated non-mutually exclusive causes of Nocturnal Enuresis in individuals with SCD include hyposthenuria leading to Nocturnal polyuria, decreased bladder capacity or Nocturnal bladder overactivity, increased arousal thresholds, and sleep disordered breathing. No evidence-based therapy for Nocturnal Enuresis in SCD exists. This review is focused on describing the natural history, postulated causes and a rational approach to the evaluation and management of Nocturnal Enuresis in children and adults with SCD.