The Experts below are selected from a list of 87 Experts worldwide ranked by ideXlab platform
R. Kenneth Marcus - One of the best experts on this subject based on the ideXlab platform.
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Non-Metal Element detection by radio-frequency glow-discharge optical-emission spectrometry (rf-GD-OES) for determination of sol–gel-immobilized nucleotides
Analytical and Bioanalytical Chemistry, 2006Co-Authors: Tim M. Brewer, R. Kenneth MarcusAbstract:A new method is presented for qualitative and quantitative determination of Non-Metal Elements present in organic analyte species immobilized in a sol–gel matrix. Nucleic acids were chosen as well-defined relevant biomolecules for which Element ratios could be used for detection and identification. Solid, lyophilized powders of ribose-form nucleotides (AMP, ADP, and ATP) were immobilized/entrapped in a methlytrimethoxysilane (mTMOS) sol–gel matrix and monitored for P (I) 214.9 nm, C (I) 193.0 nm, O (I) 130.2, and N (I) 149.3 nm emission by radio-frequency glow-discharge optical-emission spectroscopy (rf-GD-OES). Using the sol–gel method, analytical blanks were obtained by use of un-doped sol–gels. Empirical formula calculations by use of P (I) and C (I), P (I) and N (I), and P (I) and O (I) emission response ratios demonstrate the versatility of the technique as an Element and species-specific detector. Results show there is high correlation between phosphorus and oxygen emission responses and the extent of phosphorylation, demonstrating the capacity of the method to produce vital qualitative and quantitative information for the specific nucleotide. Absolute sub-nanogram detection limits were achieved for all the Elements studied.
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Non-Metal Element detection by radio-frequency glow-discharge optical-emission spectrometry (rf-GD-OES) for determination of sol-gel-immobilized nucleotides.
Analytical and Bioanalytical Chemistry, 2006Co-Authors: Tim M. Brewer, R. Kenneth MarcusAbstract:A new method is presented for qualitative and quantitative determination of Non-Metal Elements present in organic analyte species immobilized in a sol–gel matrix. Nucleic acids were chosen as well-defined relevant biomolecules for which Element ratios could be used for detection and identification. Solid, lyophilized powders of ribose-form nucleotides (AMP, ADP, and ATP) were immobilized/entrapped in a methlytrimethoxysilane (mTMOS) sol–gel matrix and monitored for P (I) 214.9 nm, C (I) 193.0 nm, O (I) 130.2, and N (I) 149.3 nm emission by radio-frequency glow-discharge optical-emission spectroscopy (rf-GD-OES). Using the sol–gel method, analytical blanks were obtained by use of un-doped sol–gels. Empirical formula calculations by use of P (I) and C (I), P (I) and N (I), and P (I) and O (I) emission response ratios demonstrate the versatility of the technique as an Element and species-specific detector. Results show there is high correlation between phosphorus and oxygen emission responses and the extent of phosphorylation, demonstrating the capacity of the method to produce vital qualitative and quantitative information for the specific nucleotide. Absolute sub-nanogram detection limits were achieved for all the Elements studied.
Tim M. Brewer - One of the best experts on this subject based on the ideXlab platform.
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Non-Metal Element detection by radio-frequency glow-discharge optical-emission spectrometry (rf-GD-OES) for determination of sol–gel-immobilized nucleotides
Analytical and Bioanalytical Chemistry, 2006Co-Authors: Tim M. Brewer, R. Kenneth MarcusAbstract:A new method is presented for qualitative and quantitative determination of Non-Metal Elements present in organic analyte species immobilized in a sol–gel matrix. Nucleic acids were chosen as well-defined relevant biomolecules for which Element ratios could be used for detection and identification. Solid, lyophilized powders of ribose-form nucleotides (AMP, ADP, and ATP) were immobilized/entrapped in a methlytrimethoxysilane (mTMOS) sol–gel matrix and monitored for P (I) 214.9 nm, C (I) 193.0 nm, O (I) 130.2, and N (I) 149.3 nm emission by radio-frequency glow-discharge optical-emission spectroscopy (rf-GD-OES). Using the sol–gel method, analytical blanks were obtained by use of un-doped sol–gels. Empirical formula calculations by use of P (I) and C (I), P (I) and N (I), and P (I) and O (I) emission response ratios demonstrate the versatility of the technique as an Element and species-specific detector. Results show there is high correlation between phosphorus and oxygen emission responses and the extent of phosphorylation, demonstrating the capacity of the method to produce vital qualitative and quantitative information for the specific nucleotide. Absolute sub-nanogram detection limits were achieved for all the Elements studied.
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Non-Metal Element detection by radio-frequency glow-discharge optical-emission spectrometry (rf-GD-OES) for determination of sol-gel-immobilized nucleotides.
Analytical and Bioanalytical Chemistry, 2006Co-Authors: Tim M. Brewer, R. Kenneth MarcusAbstract:A new method is presented for qualitative and quantitative determination of Non-Metal Elements present in organic analyte species immobilized in a sol–gel matrix. Nucleic acids were chosen as well-defined relevant biomolecules for which Element ratios could be used for detection and identification. Solid, lyophilized powders of ribose-form nucleotides (AMP, ADP, and ATP) were immobilized/entrapped in a methlytrimethoxysilane (mTMOS) sol–gel matrix and monitored for P (I) 214.9 nm, C (I) 193.0 nm, O (I) 130.2, and N (I) 149.3 nm emission by radio-frequency glow-discharge optical-emission spectroscopy (rf-GD-OES). Using the sol–gel method, analytical blanks were obtained by use of un-doped sol–gels. Empirical formula calculations by use of P (I) and C (I), P (I) and N (I), and P (I) and O (I) emission response ratios demonstrate the versatility of the technique as an Element and species-specific detector. Results show there is high correlation between phosphorus and oxygen emission responses and the extent of phosphorylation, demonstrating the capacity of the method to produce vital qualitative and quantitative information for the specific nucleotide. Absolute sub-nanogram detection limits were achieved for all the Elements studied.
Ahmed O Maslat - One of the best experts on this subject based on the ideXlab platform.
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in vitro cytogenetic testing of an organoselenium compound and its sulfur analogue in cultured rat bone marrow cells
Journal of Carcinogenesis, 2004Co-Authors: Jacob H Jacob, Ahmad M Khalil, Ahmed O MaslatAbstract:Selenium (Se) is a Non-Metal Element, occurring in varying degrees in the environment and it has been found to be a component of several enzymes. Different selenium compounds have been associated with carcinogenicity, toxicity, modification of metal toxicity and prevention of cancer. Organoselenium compounds had substantially greater bioavailability and less toxicity than that of inorganic selenium. From a chemical point of view, Se resembles sulfur (S) in many of its properties, thus, Se and S may be considered to be isosteric. The ability of a synthetic organoselenium compound; cyclopenta-dienyldicarbonyl ironselenoterephthalic acid (CSe) and its sulfur analogue (CS) in the range of 10-8 to 10-5 M, to induce sister-chormatid exchanges (SCE) and alter cell division expressed as mitotic index (MI) as well as cell survival has been investigated.
Jacob H Jacob - One of the best experts on this subject based on the ideXlab platform.
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in vitro cytogenetic testing of an organoselenium compound and its sulfur analogue in cultured rat bone marrow cells
Journal of Carcinogenesis, 2004Co-Authors: Jacob H Jacob, Ahmad M Khalil, Ahmed O MaslatAbstract:Selenium (Se) is a Non-Metal Element, occurring in varying degrees in the environment and it has been found to be a component of several enzymes. Different selenium compounds have been associated with carcinogenicity, toxicity, modification of metal toxicity and prevention of cancer. Organoselenium compounds had substantially greater bioavailability and less toxicity than that of inorganic selenium. From a chemical point of view, Se resembles sulfur (S) in many of its properties, thus, Se and S may be considered to be isosteric. The ability of a synthetic organoselenium compound; cyclopenta-dienyldicarbonyl ironselenoterephthalic acid (CSe) and its sulfur analogue (CS) in the range of 10-8 to 10-5 M, to induce sister-chormatid exchanges (SCE) and alter cell division expressed as mitotic index (MI) as well as cell survival has been investigated.
Yan Song - One of the best experts on this subject based on the ideXlab platform.
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Stabilization of Ca7Ge-type magnesium compounds by alloying of Non-Metal Elements: A new family material for reversible hydrogen storage applications
International Journal of Hydrogen Energy, 2019Co-Authors: Yuying Chen, Li-juan Wang, Yan SongAbstract:Abstract A new family material of MgnTMX2 consisted by alloying Non-Metal Element X into the Ca7Ge-type MgnTM (TM = V, Ti, or Nb; X = C, N, O, F, P, S, or Cl; n = 6 for TM = Nb and V or 7 for TM = Ti) to keep its structural stability during the de/hydrogenations was proposed. Formation energy of MgnTMX2 alloys was calculated using density functional theory to clarify the possibility of synthesizing these compounds. Calculations illustrated that compounds with X = F, O, and S satisfy both the thermal stability with negative formation energies and mechanical stability at zero pressure. The hydrogen absorption is proceed in a manner of stepwise, and finally all tetrahedron interstices were filled by 56 hydrogen atoms in the unit cell forming formula hydrides as MgnTMX2H14. It is obvious that the interstice composition plays an important role in hydrogen adsorption performance. The tetrahedral interstices composed by three Mg atoms and one transition metal own more strong ability to capture H atoms than those constituted by four Mg atoms in the initial hydrogenation process Results indicate that new family compound Mg6VO2 could be possibly ideal hydrogen storage materials in terms of dehydrogenation temperature (170–246 K) and hydrogen storage capacity (∼5.81 mass %).