Nucleolus Organizer Region

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Ellen M Rasch - One of the best experts on this subject based on the ideXlab platform.

L Sola - One of the best experts on this subject based on the ideXlab platform.

Pedro M. Galetti - One of the best experts on this subject based on the ideXlab platform.

Paul J Monaco - One of the best experts on this subject based on the ideXlab platform.

M. Schmid - One of the best experts on this subject based on the ideXlab platform.

  • Linkage of the Chicken MHC to the Nucleolus Organizer Region Visualized using Non-isotopic in situ Hybridization
    The Journal of heredity, 1991
    Co-Authors: M. Dominguez-steglich, Charles Auffray, M. Schmid
    Abstract:

    Linkage of the chicken major histocompatibility complex (B-complex) to the Nucleolus Organizer Regions (NOR) has been confirmed in situ. Nonradioactive hybridization to metaphase chromosomes using a pool of biotinylated cDNA probes for the B-F, B-L beta, and B-G genes of the B-complex gave positive signals on one or a pair of microchromosomes. Subsequent staining with silver nitrate proved these microchromosomes to be the NOR-bearing pair. The value of employing nonisotopic in situ hybridization techniques for mapping of genes and gene complexes, especially when dealing with microchromosomes, is stressed.