The Experts below are selected from a list of 138 Experts worldwide ranked by ideXlab platform
Richard S. Trompeter - One of the best experts on this subject based on the ideXlab platform.
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Long-term enteral Nutrition in infants and young children with chronic renal failure
Pediatric Nephrology, 1999Co-Authors: Sarah E. Ledermann, Vanessa Shaw, Richard S. TrompeterAbstract:An inadequate Nutritional intake is common in infants and young children with chronic and end-stage renal failure (CRF/ESRF), causing poor weight gain and growth retardation. in a programme of enteral feeding (EF), growth, Nutritional intake and outcome for oral feeding were evaluated in 35 children with CRF/ESRF, mean (range) age 1.6 (0–4.9) years at start of EF for 30 (12–60) months. Twenty-nine had a glomerular filtration rate of 12.1 (6–26) ml/min per 1.73 m2 and 6 were on peritoneal dialysis. Mean (SD) weight standard deviation scores (SDSs) in the 0 to 2-year age group (n=26) were –3.3 (1.0) 6 months before EF, –3.1 (1.3) at the start, –1.7 (1.4) at 1 year, (P=0.0003) and –1.4 (1.8) at 2 years, (P=0.0008). Height SDSs were –2.9 (0.7), –2.9 (1.2), –2.2 (1.2) (P=0.008) and –2.1 (1.3) (P=0.004). Weight SDSs in the 2 to 5-year age group (n=9) were –2.3 (1.2), –2.0 (1.1), –1.1 (1.3) (P=0.002) and –0.9 (1.0) (P=0.04). Height SDSs were –2.8 (0.6), –2.3 (0.7), –2.0 (0.7) and –2.0 (0.8). There was no change in energy intake as a percentage of the estimated average requirement, nor was this exceeded. Percentage energy from the EF in the 0 to 2 year age group remained unchanged despite an absolute increase in energy intake with age. Twenty-one have had renal transplants, of whom 86% eat and drink normally. Long-term EF prevents or reverses weight loss and growth retardation in children with CRF/ESRF, with the achievement of significant catch-up growth if started before age 2 years.
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Long-term enteral Nutrition in infants and young children with chronic renal failure
Pediatric Nephrology, 1999Co-Authors: Sarah E. Ledermann, Vanessa Shaw, Richard S. TrompeterAbstract:An inadequate Nutritional intake is common in infants and young children with chronic and end-stage renal failure (CRF/ESRF), causing poor weight gain and growth retardation. in a programme of enteral feeding (EF), growth, Nutritional intake and outcome for oral feeding were evaluated in 35 children with CRF/ESRF, mean (range) age 1.6 (0–4.9) years at start of EF for 30 (12–60) months. Twenty-nine had a glomerular filtration rate of 12.1 (6–26) ml/min per 1.73 m2 and 6 were on peritoneal dialysis. Mean (SD) weight standard deviation scores (SDSs) in the 0 to 2-year age group (n=26) were –3.3 (1.0) 6 months before EF, –3.1 (1.3) at the start, –1.7 (1.4) at 1 year, (P=0.0003) and –1.4 (1.8) at 2 years, (P=0.0008). Height SDSs were –2.9 (0.7), –2.9 (1.2), –2.2 (1.2) (P=0.008) and –2.1 (1.3) (P=0.004). Weight SDSs in the 2 to 5-year age group (n=9) were –2.3 (1.2), –2.0 (1.1), –1.1 (1.3) (P=0.002) and –0.9 (1.0) (P=0.04). Height SDSs were –2.8 (0.6), –2.3 (0.7), –2.0 (0.7) and –2.0 (0.8). There was no change in energy intake as a percentage of the estimated average requirement, nor was this exceeded. Percentage energy from the EF in the 0 to 2 year age group remained unchanged despite an absolute increase in energy intake with age. Twenty-one have had renal transplants, of whom 86% eat and drink normally. Long-term EF prevents or reverses weight loss and growth retardation in children with CRF/ESRF, with the achievement of significant catch-up growth if started before age 2 years.
Sarah E. Ledermann - One of the best experts on this subject based on the ideXlab platform.
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Long-term enteral Nutrition in infants and young children with chronic renal failure
Pediatric Nephrology, 1999Co-Authors: Sarah E. Ledermann, Vanessa Shaw, Richard S. TrompeterAbstract:An inadequate Nutritional intake is common in infants and young children with chronic and end-stage renal failure (CRF/ESRF), causing poor weight gain and growth retardation. in a programme of enteral feeding (EF), growth, Nutritional intake and outcome for oral feeding were evaluated in 35 children with CRF/ESRF, mean (range) age 1.6 (0–4.9) years at start of EF for 30 (12–60) months. Twenty-nine had a glomerular filtration rate of 12.1 (6–26) ml/min per 1.73 m2 and 6 were on peritoneal dialysis. Mean (SD) weight standard deviation scores (SDSs) in the 0 to 2-year age group (n=26) were –3.3 (1.0) 6 months before EF, –3.1 (1.3) at the start, –1.7 (1.4) at 1 year, (P=0.0003) and –1.4 (1.8) at 2 years, (P=0.0008). Height SDSs were –2.9 (0.7), –2.9 (1.2), –2.2 (1.2) (P=0.008) and –2.1 (1.3) (P=0.004). Weight SDSs in the 2 to 5-year age group (n=9) were –2.3 (1.2), –2.0 (1.1), –1.1 (1.3) (P=0.002) and –0.9 (1.0) (P=0.04). Height SDSs were –2.8 (0.6), –2.3 (0.7), –2.0 (0.7) and –2.0 (0.8). There was no change in energy intake as a percentage of the estimated average requirement, nor was this exceeded. Percentage energy from the EF in the 0 to 2 year age group remained unchanged despite an absolute increase in energy intake with age. Twenty-one have had renal transplants, of whom 86% eat and drink normally. Long-term EF prevents or reverses weight loss and growth retardation in children with CRF/ESRF, with the achievement of significant catch-up growth if started before age 2 years.
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Long-term enteral Nutrition in infants and young children with chronic renal failure
Pediatric Nephrology, 1999Co-Authors: Sarah E. Ledermann, Vanessa Shaw, Richard S. TrompeterAbstract:An inadequate Nutritional intake is common in infants and young children with chronic and end-stage renal failure (CRF/ESRF), causing poor weight gain and growth retardation. in a programme of enteral feeding (EF), growth, Nutritional intake and outcome for oral feeding were evaluated in 35 children with CRF/ESRF, mean (range) age 1.6 (0–4.9) years at start of EF for 30 (12–60) months. Twenty-nine had a glomerular filtration rate of 12.1 (6–26) ml/min per 1.73 m2 and 6 were on peritoneal dialysis. Mean (SD) weight standard deviation scores (SDSs) in the 0 to 2-year age group (n=26) were –3.3 (1.0) 6 months before EF, –3.1 (1.3) at the start, –1.7 (1.4) at 1 year, (P=0.0003) and –1.4 (1.8) at 2 years, (P=0.0008). Height SDSs were –2.9 (0.7), –2.9 (1.2), –2.2 (1.2) (P=0.008) and –2.1 (1.3) (P=0.004). Weight SDSs in the 2 to 5-year age group (n=9) were –2.3 (1.2), –2.0 (1.1), –1.1 (1.3) (P=0.002) and –0.9 (1.0) (P=0.04). Height SDSs were –2.8 (0.6), –2.3 (0.7), –2.0 (0.7) and –2.0 (0.8). There was no change in energy intake as a percentage of the estimated average requirement, nor was this exceeded. Percentage energy from the EF in the 0 to 2 year age group remained unchanged despite an absolute increase in energy intake with age. Twenty-one have had renal transplants, of whom 86% eat and drink normally. Long-term EF prevents or reverses weight loss and growth retardation in children with CRF/ESRF, with the achievement of significant catch-up growth if started before age 2 years.
Vanessa Shaw - One of the best experts on this subject based on the ideXlab platform.
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Long-term enteral Nutrition in infants and young children with chronic renal failure
Pediatric Nephrology, 1999Co-Authors: Sarah E. Ledermann, Vanessa Shaw, Richard S. TrompeterAbstract:An inadequate Nutritional intake is common in infants and young children with chronic and end-stage renal failure (CRF/ESRF), causing poor weight gain and growth retardation. in a programme of enteral feeding (EF), growth, Nutritional intake and outcome for oral feeding were evaluated in 35 children with CRF/ESRF, mean (range) age 1.6 (0–4.9) years at start of EF for 30 (12–60) months. Twenty-nine had a glomerular filtration rate of 12.1 (6–26) ml/min per 1.73 m2 and 6 were on peritoneal dialysis. Mean (SD) weight standard deviation scores (SDSs) in the 0 to 2-year age group (n=26) were –3.3 (1.0) 6 months before EF, –3.1 (1.3) at the start, –1.7 (1.4) at 1 year, (P=0.0003) and –1.4 (1.8) at 2 years, (P=0.0008). Height SDSs were –2.9 (0.7), –2.9 (1.2), –2.2 (1.2) (P=0.008) and –2.1 (1.3) (P=0.004). Weight SDSs in the 2 to 5-year age group (n=9) were –2.3 (1.2), –2.0 (1.1), –1.1 (1.3) (P=0.002) and –0.9 (1.0) (P=0.04). Height SDSs were –2.8 (0.6), –2.3 (0.7), –2.0 (0.7) and –2.0 (0.8). There was no change in energy intake as a percentage of the estimated average requirement, nor was this exceeded. Percentage energy from the EF in the 0 to 2 year age group remained unchanged despite an absolute increase in energy intake with age. Twenty-one have had renal transplants, of whom 86% eat and drink normally. Long-term EF prevents or reverses weight loss and growth retardation in children with CRF/ESRF, with the achievement of significant catch-up growth if started before age 2 years.
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Long-term enteral Nutrition in infants and young children with chronic renal failure
Pediatric Nephrology, 1999Co-Authors: Sarah E. Ledermann, Vanessa Shaw, Richard S. TrompeterAbstract:An inadequate Nutritional intake is common in infants and young children with chronic and end-stage renal failure (CRF/ESRF), causing poor weight gain and growth retardation. in a programme of enteral feeding (EF), growth, Nutritional intake and outcome for oral feeding were evaluated in 35 children with CRF/ESRF, mean (range) age 1.6 (0–4.9) years at start of EF for 30 (12–60) months. Twenty-nine had a glomerular filtration rate of 12.1 (6–26) ml/min per 1.73 m2 and 6 were on peritoneal dialysis. Mean (SD) weight standard deviation scores (SDSs) in the 0 to 2-year age group (n=26) were –3.3 (1.0) 6 months before EF, –3.1 (1.3) at the start, –1.7 (1.4) at 1 year, (P=0.0003) and –1.4 (1.8) at 2 years, (P=0.0008). Height SDSs were –2.9 (0.7), –2.9 (1.2), –2.2 (1.2) (P=0.008) and –2.1 (1.3) (P=0.004). Weight SDSs in the 2 to 5-year age group (n=9) were –2.3 (1.2), –2.0 (1.1), –1.1 (1.3) (P=0.002) and –0.9 (1.0) (P=0.04). Height SDSs were –2.8 (0.6), –2.3 (0.7), –2.0 (0.7) and –2.0 (0.8). There was no change in energy intake as a percentage of the estimated average requirement, nor was this exceeded. Percentage energy from the EF in the 0 to 2 year age group remained unchanged despite an absolute increase in energy intake with age. Twenty-one have had renal transplants, of whom 86% eat and drink normally. Long-term EF prevents or reverses weight loss and growth retardation in children with CRF/ESRF, with the achievement of significant catch-up growth if started before age 2 years.
Agostino Pierro - One of the best experts on this subject based on the ideXlab platform.
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Randomized clinical trial of glutamine‐supplemented versus standard parenteral Nutrition in infants with surgical gastrointestinal disease
The British journal of surgery, 2012Co-Authors: Evelyn Ong, Simon Eaton, Angela Wade, V. Horn, Paul D. Losty, Joe Curry, I. D. Sugarman, Nigel Klein, Agostino PierroAbstract:Background: Addition of glutamine to parenteral Nutrition in surgical infants remains controversial. The aim of this trial was to determine whether glutamine supplementation of parenteral Nutrition in infants requiring surgery would reduce the time to full enteral feeding and/or decrease the incidence of sepsis and septicaemia. Methods: A prospective double-blind multicentre randomized clinical trial was performed in surgical infants less than 3 months old who required parenteral Nutrition. Patients were allocated to treatment or control groups by means of minimization. infants received either 0·6 g per kg per day alanyl-glutamine (treatment group) or isonitrogenous isocaloric parenteral Nutrition (control group) until full enteral feeding was achieved. Primary outcomes were time to full enteral feeding and incidence of sepsis. Cox regression analysis was used to compare time to full enteral feeding, and to calculate risk of sepsis/septicaemia. Results: A total of 174 patients were randomized, of whom 164 completed the trial and were analysed (82 in each group). There was no difference in time to full enteral feeding or time to first enteral feeding between groups, and supplementation with glutamine had no effect on the overall incidence of sepsis or septicaemia. However, during total parenteral Nutrition (before the first enteral feed), glutamine administration was associated with a significantly decreased risk of developing sepsis (hazard ratio 0·33, 95 per cent confidence interval 0·15 to 0·72; P = 0·005). Conclusion: Glutamine supplementation during parenteral Nutrition did not reduce the incidence of sepsis in surgical infants with gastrointestinal disease. Registration number: ISRCTN83168963 (http://www.controlled-trials.com). Copyright © 2012 British Journal of Surgery Society Ltd. Published by John Wiley & Sons, Ltd.
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Perioperative Nutrition in infants and children.
Nutrition (Burbank Los Angeles County Calif.), 1999Co-Authors: Agostino PierroAbstract:The survival rate of newborn infants affected by isolated congenital gastrointestinal abnormalities such as intestinal atresia, meconium ileus, omphalocele, and gastroschisis has improved considerably over the past 20 y, and is now .90% in most pediatric surgical centers. The introduction of parenteral Nutrition and advancements in Nutritional management are two of the factors mainly responsible for this improvement. The newborn infant is in a critical epoch of development, not only for the organism as a whole, but also for the individual organs and most significantly for the brain.1 Adequate Nutrition in the neonatal period is necessary to avoid the adverse effects of malNutrition on morbidity and mortality,2 and to minimize the future menace of stunted mental and physical development.1 The Nutritional requirements of adolescents do not differ significantly from those of adults.3 Therefore, this article will focus on the Nutritional requirements of infants and young children.
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cholestatic jaundice in newborn infants receiving parenteral Nutrition
Seminars in Neonatology, 1996Co-Authors: Agostino PierroAbstract:Hepatic cholestasis is a common complication of long-term parenteral Nutrition in infants and children. The factors contributing to the development of this complication are multifactorial and not yet completely determined. Neonates, especially those born preterm, are at particular risk. infection, intestinal bacterial overgrowth and lack of enteral stimulation contribute significantly to the development of the disease. The data on direct toxicity of parenteral nutrients is contradictory and mainly based on experimental animal models that do not reproduce the liver damage observed in infants and children. Enteral feedings should be started as soon as possible to prevent parenteral Nutrition-related cholestasis. The efficacy of various drug treatments in preventing parenteral Nutrition-related cholestasis have not been proved.
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gall bladder contractility in neonates effects of parenteral and enteral feeding
Archives of Disease in Childhood-fetal and Neonatal Edition, 1995Co-Authors: G Jawaheer, Agostino Pierro, D A Lloyd, N J ShawAbstract:The gall bladder size was measured in 30 newborn infants: 18 had been fed parenterally and 12 enterally. The two groups were comparable for gestational age, birthweight, postnatal age and study weight. Exclusion criteria were haemodynamic instability, septicaemia, abdominal disease and opioid treatment. Gall bladder size was measured at 15 minute intervals for 90 minutes using real-time ultrasonography and the volume calculated using the ellipsoid method. Parenterally fed infants had further measurements at 120, 150, and 360 minutes. The gall bladder was significantly larger in parenterally fed infants than in enterally fed infants (p = 0.0001). in enterally fed infants a 50% reduction in gall bladder volume was observed 15 minutes after starting the feed with a return to baseline volume by 90 minutes. in parenterally fed infants there was no gall bladder contraction. Such information may give insight into the pathophysiology of hepato-biliary complications during parenteral Nutrition in infants.
Daniel T. Robinson - One of the best experts on this subject based on the ideXlab platform.
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Energy and Protein intake During the Transition from Parenteral to Enteral Nutrition in infants of Very Low Birth Weight
The Journal of pediatrics, 2018Co-Authors: Gustave H. Falciglia, Karna Murthy, Jane L. Holl, Hannah L. Palac, Yuliya Oumarbaeva, Donna M. Woods, Daniel T. RobinsonAbstract:Objective To evaluate the association between Nutrition delivery practices and energy and protein intake during the transition from parenteral to enteral Nutrition in infants of very low birth weight (VLBW). Study design This was a retrospective analysis of 115 infants who were VLBW from a regional neonatal intensive care unit. Changes in energy and protein intake were estimated during transition phase 1 (0% enteral); phase 2 (>0, ≤33.3% enteral); phase 3 (>33.3, ≤66.7% enteral); phase 4 (>66.7, Results in phases 2 and 3, infants receiving feeding fortification received less protein than infants who were unfortified (−1.1 and −0.3 g/kg/d, respectively; P Conclusions infants paradoxically received less protein and energy on days with early fortification, suggesting that clinicians may lack easily accessible data to detect the association between Nutrition delivery practices and overall Nutrition in infants who are VLBW.
