Oncomelania hupensis

14,000,000 Leading Edge Experts on the ideXlab platform

Scan Science and Technology

Contact Leading Edge Experts & Companies

Scan Science and Technology

Contact Leading Edge Experts & Companies

The Experts below are selected from a list of 675 Experts worldwide ranked by ideXlab platform

Anis Nurwidayati - One of the best experts on this subject based on the ideXlab platform.

  • HUBUNGAN ANTARA KEPADATAN DAN TINGKAT INFEKSI SERKARIA Schistosoma japonicum PADA KEONG Oncomelania hupensis lindoensis DENGAN KASUS SCHISTOSOMIASIS DI DAERAH ENDEMIS SCHISTOSOMIASIS, SULAWESI TENGAH
    Badan Penelitian dan Pengembangan Kesehatan, 2018
    Co-Authors: Anis Nurwidayati, Junus Widjaja, Samarang Samarang, Made Agus Nurjana, Intan Tolistiawaty, Phetisya Pamela Frederika Sumolang
    Abstract:

    Schistosomiasis in Indonesia is found only in theNapu and Bada Highlands, Poso District and Lindu Highlands, Sigi District, Central Sulawesi Province. Schistosomiasis in Indonesia is caused by Schistosoma japonicum and Oncomelania hupensis lindoensis is the intermediate snail. The mapping of snail focci areas in 2017 showed that there was a significant change in the spread of the snail's focus. This paper aimed to describe the density and infection rate of cercariae S. japonicum on the snail in the endemic areas of schistosomiasis in Central Sulawesi Province. The mean O.hupensis lindoensis snail density in Napu ranged from 0.9 to 6.6/m2, with mean rates of cercariae infections ranging from 0.4% to 21.4%. The snail density average in Lindu ranging from 3/m2 to 69,1/m2, with 4.4%-72.9% of cercariae infections. In bada the snail density ranged from 0.1 to 4.9/m2, with mean rates of cercariae infections ranging from 0% to 14.9%. Bivariate analysis showed there was no correlation among snail density and cercariae infection rate with schistosomiasis case (p value> 0.05). Schistosomiasis di Indonesia hanya ditemukan di Propinsi Sulawesi Tengah, yaitu Dataran Tinggi Napu dan Dataran Tinggi Bada, Kabupaten Poso serta Dataran Tinggi Lindu, Kabupaten Sigi. Schistosomiasis di Indonesia disebabkan oleh Schistosoma japonicum dengan hospes perantara keong Oncomelania hupensis lindoensis. Pemetaan daerah fokus pada tahun 2017 menunjukkan bahwa  terdapat perubahan yang signifikan dalam penyebaran fokus keong. Tulisan ini bertujuan untuk menggambarkan kepadatan dan infection rate serkaria S.japonicum pada keong perantara schistosomiasis di wilayah endemis schistosomiasis di Provinsi Sulawesi Tengah. Rerata kepadatan keong O.hupensis lindoensis di Napu berkisar dari 0,9 – 6,6/m2, dengan rerata tingkat infeksi serkaria berkisar antara 0,4% sampai 21,4%, di Lindu kepadatan keong berkisar antara 3/m2 sampai 69,1/m2, dengan tingkat infeksi serkaria 4,4%-72,9%, dan di Bada kepadatan keong berkisar antara 0,1 – 4,9/m2, dengan rerata tingkat infeksi serkaria berkisar antara 0 % sampai 14,9%. Analisis bivariat menunjukkan tidak ada korelasi antara kepadatan keong dan tingkat infeksi serkaria dengan jumlah kasus schistosomiasis nilai p value > 0.05

  • Kepadatan dan Tingkat Infeksi Serkaria Schistosoma japonicum pada Keong Oncomelania hupensis lindoensis dengan Kasus Schistosomiasis di Daerah Endemis Schistosomiasis, Sulawesi Tengah
    Badan Penelitian dan Pengembangan Kesehatan, 2018
    Co-Authors: Anis Nurwidayati, Junus Widjaja, Samarang Samarang, Made Agus Nurjana, Intan Tolistiawaty, Phetisya Pfs
    Abstract:

    Abstract Schistosomiasis in Indonesia only found in Napu and Bada Highlands, Poso district and Lindu Highlands in Sigi district, Central Sulawesi Province. Schistosomiasis in Indonesia caused by Schistosoma japonicum and Oncomelania hupensis lindoensis is the intermediate snail host. The mapping of snail foci areas in 2017 showed that there was a significant change in the spread of the snail's foci. This paper aimed to describe the density and infection rate of S. japonicum cercariae in the snail host in the endemic areas of schistosomiasis in Central Sulawesi Province. The mean O.hupensis lindoensis snail density in Napu ranged from 0.9 to 6.6/m2, with mean rates of cercariae infections ranging from 0.4% to 21.4%. The snail density average in Lindu ranging from 3/m2 to 69,1/m2, with 4.4%-72.9% of cercariae infections. In bada the snail density ranged from 0.1 to 4.9/m2, with mean rates of cercariae infections ranging from 0% to 14.9%. Bivariate analysis showed there was no correlation between snail density and cercariae infection rate with schistosomiasis case (p value> 0.05). Keywords : Schistosomiasis, density, infection rate, Oncomelania hupensis lindoensis, Central Sulawesi Abstrak Schistosomiasis di Indonesia hanya ditemukan di Propinsi Sulawesi Tengah, yaitu Dataran Tinggi Napu dan Dataran Tinggi Bada, Kabupaten Poso serta Dataran Tinggi Lindu, Kabupaten Sigi. Schistosomiasis di Indonesia disebabkan oleh Schistosoma japonicum dengan hospes perantara keong Oncomelania hupensis lindoensis. Pemetaan daerah fokus pada tahun 2017 menunjukkan bahwa terdapat perubahan yang signifikan dalam penyebaran fokus keong. Tulisan ini bertujuan untuk menggambarkan kepadatan dan infection rate serkaria S.japonicum pada keong perantara schistosomiasis di wilayah endemis schistosomiasis di Provinsi Sulawesi Tengah. Rerata kepadatan keong O.hupensis lindoensis di Napu berkisar dari 0,9 – 6,6/m2, dengan rerata tingkat infeksi serkaria berkisar antara 0,4% sampai 21,4%, di Lindu kepadatan keong berkisar antara 3/m2 sampai 69,1/m2, dengan tingkat infeksi serkaria 4,4%¬72,9%, dan di Bada kepadatan keong berkisar antara 0,1 – 4,9/m2, dengan rerata tingkat infeksi serkaria berkisar antara 0 % sampai 14,9%. Analisis bivariat menunjukkan tidak ada korelasi antara kepadatan keong dan tingkat infeksi serkaria dengan jumlah kasus schistosomiasis nilai p value > 0.05. Kata kunci: Schistosomiasis, kepadatan, tingkat infeksi, Oncomelania hupensis lindoensis, Sulawesi Tenga

  • Kondisi Fokus Keong Perantara Schistosomiasis Oncomelania hupensis lindoensis di Empat Desa Daerah Integrasi Program Lintas Sektor, Sulawesi Tengah
    Balai Litbang P2B2 Banjarnegara, 2018
    Co-Authors: Samarang Pawakkangi, Phetisya Pamela Frederika Sumolang, Anis Nurwidayati, Gunawan Gunawan, Leonardo Taruk Lobo, Murni Murni
    Abstract:

    Schistosomiasis is a zoonotic parasitic disease with Oncomelania hupensis lindoensis snail as host. The spread of O. hupensis lindoensis snail habitat was found in the three areas of the Napu, Bada and Lindu Highlands with an infection rate above 1%. The last focus area mapping was conducted in 2008. Based on this, re-focus mapping was conducted in cross sectoral integration program intervention areas, in Napu, Bada and Lindu highlands, on May-November in 2016. The study was aimed to identify the distribution of primary and secondary focus area of O. hupensis lindoensis snail in the intervention areas in four villages. Cross sectional design was used in the study. The snail survey using the man/minute method, the Schistosoma japonicum worm serkaria examination on the snail using the crushing method. The results found there were 91.4% secondary focus and 8.6% primary focus in the area of study. The focus of O. hupensis lindoensis snail in Sedoa Village were 33 focus with 45% positive sercaria, Watutau Village two focus with 50% positive sercaria, Tomehipi Village eight focus with 13% positive sercaria and Tomado Village 15 focus with 67% positive sercaria. The focus distribution in the cross sectoral program integration area is largely a secondary focus with less number of  focus number but a wider focus area. The highest infection rate was in Tomado Village. ABSTRAK Schistosomiasis adalah penyakit parasitik bersifat zoonosis dengan inang perantara keong Oncomelania hupensis lindoensis. Penyebaran habitat keong O. h. lindoensis di Sulawesi Tengah ditemukan di tiga wilayah yaitu Dataran Tinggi Napu, Bada, dan Lindu dengan angka infeksi  diatas 1%. Pemetaan fokus terakhir dilakukan tahun 2008, sehingga dilakukan pemutakhiran data distribusi daerah fokus primer dan sekunder di empat desa daerah integrasi program lintas sektor, Desa Sedoa, dan Watutau di Dataran Tinggi Napu, Desa Tomehipi Dataran Tinggi Bada, dan Desa Tomado di Dataran Tinggi Lindu. Penelitian dilakukan Bulan Mei-Nopember tahun 2016, dengan desain penelitian cross sectional. Survei keong menggunakan metode man/minute, pemeriksaan serkaria cacing Schistosoma japonicum pada keong  menggunakan metode crushing. Hasil penelitian ditemukan 91,4% fokus sekunder dan 8,6% fokus primer. Di Desa Sedoa sebanyak 33 fokus, 45% diantaranya positif serkaria dan di Desa Watutau 50% dari dua fokus sekunder ditemukan positif serkaria. Delapan daerah fokus ditemukan di Desa Tomehipi, 13% diantaranya positif serkaria. Sebanyak 15 daerah fokus ditemukan di Desa Tomado, 67% positif serkaria. Distribusi fokus di daerah integrasi program lintas sektor sebagian besar merupakan fokus sekunder dengan jumlah fokus menurun namun area fokus semakin luas. Persentase fokus positif serkaria tertinggi ditemukan di Dataran Tinggi Lindu Desa Tomado

  • Efektivitas Pelepasan Itik dalam Pengendalian Keong Oncomelania hupensis lindoensis di Daerah Fokus Schistosomiasis Napu, Kabupaten Poso, Sulawesi Tengah
    Badan Penelitian dan Pengembangan Kesehatan, 2016
    Co-Authors: Anis Nurwidayati, Jastal Jastal, Gunawan Gunawan, Murni Murni
    Abstract:

    AbstractSchistosomiasis is still a health problem in endemic areas of Napu, Poso, Central Sulawesi. Snail Oncomelania hupensis lindoensis, the intermediate host of schistosomiasis is widespread in the region of Napu. The snail control is done by mechanical, chemical, and biological agents. using molluscicide and also by biological agent. One of biological agent that used for snail control is duck. The effectiveness of ducks release as a biological control for schistosomiasis has not been proven. This research aimed to determine the effectivity of duck for snail control. This research was conducted from March to December 2015 in three villages. Mekarsari Village, Maholo Village and Watumaeta village. The result based on statistic analysis showed that duck was effective only in Mekarsari village, not in Watumaeta and Maholo Villages. There was no significant difference between snail population in intervention area and non intervention area. From the result can be concluded that using duck release to control snails was only effective in spesific type of focci that was not full of grass and has no stone substrate, such as in Mekarsari village.Keywords : Schistosomiasis, duck, Oncomelania hupensis lindoensis snails, NapuAbstrakSchistosomiasis saat ini masih menjadi masalah kesehatan di daerah endemis Napu, Kabupaten Poso, Sulawesi Tengah. Keong Oncomelania hupensis lindoensis, perantara schistosomiasis tersebar luas di wilayah Napu. Program pengendalian keong perantara schistosomiasis yang dilakukan adalah secara mekanik, kimiawi dengan moluskisida, dan secara biologi. Pengendalian keong secara biologi yang dilakukan adalah pelepasan itik di daerah fokus keong O.h.lindoensis, akan tetapi hal tersebut dibuktikan efektivitasnya. Penelitian ini bertujuan untuk menentukan efektivitas pelepasan itik dalam pengendalian keong perantara schistosomiasis, Oncomelania hupensis lindoensis di Napu, Kabupaten Poso, Sulawesi Tengah. Penelitian dilakukan pada bulan Maret-Desember 2015 di daerah fokus keong Desa Mekarsari, Desa Maholo, dan Desa Watumaeta, Kabupaten Poso, Sulawesi Tengah. Hasil penelitian menunjukkan adanya penurunan populasi keong yang signifikan secara statistik setelah pelepasan itik di Desa Mekarsari, tetapi tidak di Watumaeta dan Desa Maholo. Tidak terdapat perbedaan yang signifikan antara populasi keong di daerah yang dilepas itik dengan daerah non intervensi. Pelepasan itik untuk pengendalian keong O.h.lindoensis menunjukkan hasil yang signifikan secara statistik pada daerah fokus tertentu, yaitu daerah fokus berupa saluran air yang tidak ditumbuhi rumput tebal, atau dengan substrat bebatuan seperti di Desa Mekarsari.Kata kunci : Schistosomiasis, itik, keong Oncomelania hupensis lindoensis, Napu

Murni Murni - One of the best experts on this subject based on the ideXlab platform.

  • Kondisi Fokus Keong Perantara Schistosomiasis Oncomelania hupensis lindoensis di Empat Desa Daerah Integrasi Program Lintas Sektor, Sulawesi Tengah
    Balai Litbang P2B2 Banjarnegara, 2018
    Co-Authors: Samarang Pawakkangi, Phetisya Pamela Frederika Sumolang, Anis Nurwidayati, Gunawan Gunawan, Leonardo Taruk Lobo, Murni Murni
    Abstract:

    Schistosomiasis is a zoonotic parasitic disease with Oncomelania hupensis lindoensis snail as host. The spread of O. hupensis lindoensis snail habitat was found in the three areas of the Napu, Bada and Lindu Highlands with an infection rate above 1%. The last focus area mapping was conducted in 2008. Based on this, re-focus mapping was conducted in cross sectoral integration program intervention areas, in Napu, Bada and Lindu highlands, on May-November in 2016. The study was aimed to identify the distribution of primary and secondary focus area of O. hupensis lindoensis snail in the intervention areas in four villages. Cross sectional design was used in the study. The snail survey using the man/minute method, the Schistosoma japonicum worm serkaria examination on the snail using the crushing method. The results found there were 91.4% secondary focus and 8.6% primary focus in the area of study. The focus of O. hupensis lindoensis snail in Sedoa Village were 33 focus with 45% positive sercaria, Watutau Village two focus with 50% positive sercaria, Tomehipi Village eight focus with 13% positive sercaria and Tomado Village 15 focus with 67% positive sercaria. The focus distribution in the cross sectoral program integration area is largely a secondary focus with less number of  focus number but a wider focus area. The highest infection rate was in Tomado Village. ABSTRAK Schistosomiasis adalah penyakit parasitik bersifat zoonosis dengan inang perantara keong Oncomelania hupensis lindoensis. Penyebaran habitat keong O. h. lindoensis di Sulawesi Tengah ditemukan di tiga wilayah yaitu Dataran Tinggi Napu, Bada, dan Lindu dengan angka infeksi  diatas 1%. Pemetaan fokus terakhir dilakukan tahun 2008, sehingga dilakukan pemutakhiran data distribusi daerah fokus primer dan sekunder di empat desa daerah integrasi program lintas sektor, Desa Sedoa, dan Watutau di Dataran Tinggi Napu, Desa Tomehipi Dataran Tinggi Bada, dan Desa Tomado di Dataran Tinggi Lindu. Penelitian dilakukan Bulan Mei-Nopember tahun 2016, dengan desain penelitian cross sectional. Survei keong menggunakan metode man/minute, pemeriksaan serkaria cacing Schistosoma japonicum pada keong  menggunakan metode crushing. Hasil penelitian ditemukan 91,4% fokus sekunder dan 8,6% fokus primer. Di Desa Sedoa sebanyak 33 fokus, 45% diantaranya positif serkaria dan di Desa Watutau 50% dari dua fokus sekunder ditemukan positif serkaria. Delapan daerah fokus ditemukan di Desa Tomehipi, 13% diantaranya positif serkaria. Sebanyak 15 daerah fokus ditemukan di Desa Tomado, 67% positif serkaria. Distribusi fokus di daerah integrasi program lintas sektor sebagian besar merupakan fokus sekunder dengan jumlah fokus menurun namun area fokus semakin luas. Persentase fokus positif serkaria tertinggi ditemukan di Dataran Tinggi Lindu Desa Tomado

  • Efektivitas Pelepasan Itik dalam Pengendalian Keong Oncomelania hupensis lindoensis di Daerah Fokus Schistosomiasis Napu, Kabupaten Poso, Sulawesi Tengah
    Badan Penelitian dan Pengembangan Kesehatan, 2016
    Co-Authors: Anis Nurwidayati, Jastal Jastal, Gunawan Gunawan, Murni Murni
    Abstract:

    AbstractSchistosomiasis is still a health problem in endemic areas of Napu, Poso, Central Sulawesi. Snail Oncomelania hupensis lindoensis, the intermediate host of schistosomiasis is widespread in the region of Napu. The snail control is done by mechanical, chemical, and biological agents. using molluscicide and also by biological agent. One of biological agent that used for snail control is duck. The effectiveness of ducks release as a biological control for schistosomiasis has not been proven. This research aimed to determine the effectivity of duck for snail control. This research was conducted from March to December 2015 in three villages. Mekarsari Village, Maholo Village and Watumaeta village. The result based on statistic analysis showed that duck was effective only in Mekarsari village, not in Watumaeta and Maholo Villages. There was no significant difference between snail population in intervention area and non intervention area. From the result can be concluded that using duck release to control snails was only effective in spesific type of focci that was not full of grass and has no stone substrate, such as in Mekarsari village.Keywords : Schistosomiasis, duck, Oncomelania hupensis lindoensis snails, NapuAbstrakSchistosomiasis saat ini masih menjadi masalah kesehatan di daerah endemis Napu, Kabupaten Poso, Sulawesi Tengah. Keong Oncomelania hupensis lindoensis, perantara schistosomiasis tersebar luas di wilayah Napu. Program pengendalian keong perantara schistosomiasis yang dilakukan adalah secara mekanik, kimiawi dengan moluskisida, dan secara biologi. Pengendalian keong secara biologi yang dilakukan adalah pelepasan itik di daerah fokus keong O.h.lindoensis, akan tetapi hal tersebut dibuktikan efektivitasnya. Penelitian ini bertujuan untuk menentukan efektivitas pelepasan itik dalam pengendalian keong perantara schistosomiasis, Oncomelania hupensis lindoensis di Napu, Kabupaten Poso, Sulawesi Tengah. Penelitian dilakukan pada bulan Maret-Desember 2015 di daerah fokus keong Desa Mekarsari, Desa Maholo, dan Desa Watumaeta, Kabupaten Poso, Sulawesi Tengah. Hasil penelitian menunjukkan adanya penurunan populasi keong yang signifikan secara statistik setelah pelepasan itik di Desa Mekarsari, tetapi tidak di Watumaeta dan Desa Maholo. Tidak terdapat perbedaan yang signifikan antara populasi keong di daerah yang dilepas itik dengan daerah non intervensi. Pelepasan itik untuk pengendalian keong O.h.lindoensis menunjukkan hasil yang signifikan secara statistik pada daerah fokus tertentu, yaitu daerah fokus berupa saluran air yang tidak ditumbuhi rumput tebal, atau dengan substrat bebatuan seperti di Desa Mekarsari.Kata kunci : Schistosomiasis, itik, keong Oncomelania hupensis lindoensis, Napu

Xiao-nong Zhou - One of the best experts on this subject based on the ideXlab platform.

  • application of bio inspired control of amphihex i in detection of Oncomelania hupensis the amphibious snail intermediate host of schistosoma japonicum
    Industrial Robot-an International Journal, 2017
    Co-Authors: Y Zhou, Xiao-nong Zhou, Bin Zhong, Tao Fang, Jiming Liu, Shiwu Zhang
    Abstract:

    Purpose This paper aims to construct a central pattern generator (CPG) network that comprises coupled nonlinear oscillators to implement diversified locomotion gaits of robot AmphiHex-I. With the gaits, AmphiHex-I will have a strong locomotion ability in an amphibious environment, which is motivated by a novel public health application to detect the amphibious snail, Oncomelania hupensis, the snail intermediate host of Schistosoma japonicum, as an amphibious robot-based tool for schistosomiasis surveillance and response in the future. Design/methodology/approach First, the basis neural network was built by adopting six Hopf nonlinear oscillators which corresponded to six legs. Then, the correlation between the self-excited harmonic output signals generated from CPGs and various gaits was established. In view of requirements on its field application, the authors added a telecontrol system and an on-board battery to support the real-life remote control and a high-definition camera and a global positioning system module to acquire images and position information. Finally, the authors conducted the testing experiments on several tasks, e.g. detecting the distribution of Oncomelania hupensis snails. Findings The results demonstrate that the CPG is effective in controlling the robot’s diversified locomotion gaits. In addition, the robot is capable of fulfilling several testing tasks in the experiments. Originality/value The research provides a method based on CPG to control a hexapod robot with multiple motion patterns, which can effectively overcome the difficulty of motion control simply by changing certain mathematical parameters of a nonlinear equation, such as frequency, phase difference and offset angle, so as to realize the gait transitions. Also, using such a robot to probe the distribution of snails offers another way to tackle this laborious job, especially in some odious terrains, which will hence broaden the application of AmphiHex-I to vector surveillance in the fields of public health.

  • the genetic diversity and geographical separation study of Oncomelania hupensis populations in mainland china using microsatellite loci
    Parasites & Vectors, 2016
    Co-Authors: Wei Guan, Shi-zhu Li, Bonnie L Webster, David Rollinson, Xiao-nong Zhou
    Abstract:

    Background Oncomelania hupensis is the unique intermediate host of Schistosoma japonicum, which plays a crucial role in the transmission of schistosomiasis. The endemic area of S. japonicum is strictly consistent with the geographical distribution of O. hupensis.

  • phylogenetic performance of mitochondrial protein coding genes of Oncomelania hupensis in resolving relationships between landscape populations
    Journal of Systematics and Evolution, 2013
    Co-Authors: L I Shizhu, Lv Shan, Qiang Wang, Li Zhang, Yingjun Qian, Xiao-nong Zhou
    Abstract:

    Oncomelania hupensis is the unique intermediate host of Schistosoma japonicum, which plays a key role in the transmission of human blood fluke Schistosoma. The complete mitochondrial (mt) genome of O. hupensis has been characterized; however, the phylogenetic performance of mt protein-coding genes (PCGs) of the snail remain unclear. In this study, 11 whole mt genomes of snails collected from four different ecological settings in China and the Philippines were sequenced. The mt genome sizes ranged from 15 183 to 15 216 bp, with the G + C contents from 32.4% to 33.4%. A total of 15 251 characters were generated from the multiple sequence alignment. Of 2711 (17.8%) polymorphic sites, 56.22% (1524) were parsimony sites. The mt genomes' phylogenetic trees were reconstructed using minimum evolution, neighbor joining, maximum likelihood, maximum parsimony, and Bayesian tree estimate methods, and two main distinct clades were identified: (i) the isolate from mountainous regions; (ii) the remaining isolate which included three inner branches. All phylogenetic trees of the 13 PCGs were generated by running 1000 bootstrap replicates and compared with the complete mtDNA tree, the classification accuracy ranging from 21.23% to 87.87%, the topological distance of phylogenetic trees between PCGs ranging from 5 to 14. Therefore, the performance of PCGs can be divided into good condition (COI, ND2, ND5, and ND3), medium (COII, ATP6, ND1, ND6, Cytb, ND4, and COIII), poor (ATP8 and ND4L). This study represents the first analysis of mt genome diversity of the O. hupensis snail and phylogenetic performance of mt PCGs. It presents clear evidence that the snail populations can be separated into four landscape genetic populations in mainland China based on whole mt genomes. The identification of the phylogenetic performance of PCGs provides new insight into the intensive genetic diversity study using mtDNA markers for the snail.

  • isolation and characterization of 15 new microsatellite markers in Oncomelania hupensis the snail intermediate host of schistosoma japonicum in mainland china
    International Journal of Molecular Sciences, 2012
    Co-Authors: Li Zhang, Shi-zhu Li, Qiang Wang, Yingjun Qian, Pin Yang, Xiao-nong Zhou
    Abstract:

    Oncomelania hupensis is the unique intermediate host of Schistosoma japonicum, which plays a key role during the transmission of schistosomiasis. It is mainly found in the Yangtze River valley and mountains or hills in southwest China. In this paper, we described 15 new microsatellite makers in O. hupensis. Polymorphism of each locus was assessed in 80 individuals from four wild populations (n = 20 per population). The number of alleles per locus ranged from 6 to 29, with an average of 15.8. The observed (HO) and expected (HE) heterozygosities varied from 0.397 to 0.851 and from 0.696 to 0.948, respectively. These microsatellite markers will be useful for population genetic studies and genome mapping in O. hupensis.

  • compensatory density feedback of Oncomelania hupensis populations in two different environmental settings in china
    Parasites & Vectors, 2011
    Co-Authors: Guojing Yang, Xiao-nong Zhou, Le-ping Sun, Jurg Utzinger, Bo Zhong, Dongchuan Qiu, Corey J A Bradshaw
    Abstract:

    Background: The most recent strategy for schistosomiasis control in the People’s Republic of China aims to reduce the likelihood of environmental contamination of schistosome eggs. Despite considerable progress, it is believed that achievements would be further consolidated with additional intermediate host snail control measures. We provide an empirical framework for discerning the relative contribution of intrinsic effects (density feedback) from other extrinsic drivers of snail population dynamics. Methods: We set up experiments in two study locations to collect reproduction data of Oncomelania hupensis, the intermediate host snail of Schistosoma japonicum. We applied a set of four population dynamic models that have been widely used to study phenomenological time-series data to examine the properties of demographic density feedback patterns from abundance data. We also contrasted the obtained results with the component feedback of density on survival rate to determine whether adult survival was the principal driver of the demographic feedback observed. Results: Demographic density feedback models (Ricker- and Gompertz-logistic) accounted for > 99% of Akaike’s information criterion model weight, with the Gompertz ranking highest in all O. hupensis population groups. We found some evidence for stronger compensatory feedback in the O. hupensis population from Sichuan compared to a Jiangsu population. Survival rates revealed strong component feedback, but the log-linear relationships (i.e. Gompertz) had less support in the demographic feedback analysis. Conclusions: Our findings indicate that integrated schistosomiasis control measures must continue to reduce parasite abundance further because intermediate host snail populations tend to grow exponentially at low densities, especially O. hupensis populations in mountainous regions. We conclude that density feedback in adult survival is the principal component contribution to the demographic phenomenon observed in the population fitness (r)-abundance relationship.

Shi-zhu Li - One of the best experts on this subject based on the ideXlab platform.

  • temporal transcriptome change of Oncomelania hupensis revealed by schistosoma japonicum invasion
    Cell & Bioscience, 2020
    Co-Authors: Xiaojin Mo, Xinyu Feng, Ying Jiang, Wei Hu, Shi-zhu Li
    Abstract:

    The freshwater snail Oncomelania hupensis is the obligate intermediate host for Schistosoma japonicum in China. Transcriptomic examination of snail–schistosome interactions can provide valuable information of host response at physiological and immune levels. To investigate S. japonicum-induced changes in O. hupensis gene expression, we utilized high-throughput sequencing to identify transcripts that were differentially expressed between infected snails and their uninfected controls at two key time-point, Day 7 and Day 30 after challenge. Time-series transcriptomic profiles were analyzed using R package DESeq 2, followed by GO, KEGG and (weighted gene correlation network analysis) WGCNA analysis to elucidate and identify important molecular mechanism, and subsequently understand host–parasite relationship. The identified unigenes was verified by bioinformatics and real-time PCR. Possible adaptation molecular mechanisms of O. hupensis to S. japonicum challenge were proposed. Transcriptomic analyses of O. hupensis by S. japonicum invasion yielded billion reads including 92,144 annotated transcripts. Over 5000 differentially expressed genes (DEGs) were identified by pairwise comparisons of infected libraries from two time points to uninfected libraries in O. hupensis. In total, 6032 gene ontology terms and 149 KEGG pathways were enriched. After the snails were infected with S. japonicum on Day 7 and Day 30, DEGs were shown to be involved in many key processes associated with biological regulation and innate immunity pathways. Gene expression patterns differed after exposure to S. japonicum. Using WGCNA, 16 modules were identified. Module-trait analysis identified that a module involved in RNA binding, ribosome, translation, mRNA processing, and structural constituent of ribosome were strongly associated with S. japonicum invasion. Many of the genes from enriched KEGG pathways were involved in lysosome, spliceosome and ribosome, indicating that S. japonicum invasion may activate the regulation of ribosomes and immune response to infection in O. hupensis. Our analysis provided a temporally dynamic gene expression pattern of O. hupensis by S. japonicum invasion. The identification of gene candidates serves as a foundation for future investigations of S. japonicum infection. Additionally, major DEGs expression patterns and putative key regulatory pathways would provide useful information to construct gene regulatory networks between host-parasite crosstalk.

  • intestinal microbiome profiles in Oncomelania hupensis in mainland china
    Acta Tropica, 2020
    Co-Authors: Wei Guan, Wei Wang, Qiang Wang, Haonan Wu, Lanhua Li, Shan Lv, Jing Xu, Shi-zhu Li
    Abstract:

    Abstract Oncomelania hupensis plays a significant role in the transmission of schistosomiasis japonica, which remains a major public health concern in China. Understanding the biological characteristics of O. hupensis is a prerequisite for its control; however, there are currently no studies investigating the intestinal microbiota of the O. hupensis snail. This study aimed to profile the intestinal microbiome of O. hupensis across different ecological landscapes in mainland China. DNA was extracted from the intestines of the collected snails and the bacterial communities were detected using 454 pyrosequencing. A total of 3,799 operational taxonomic units (OTUs) were obtained, and Proteobacteria, Firmicutes, and Actinobacteria were identified as the dominant bacterial taxa at the phylum level. Bacillus and Lactococcus were the most common genera in samples obtained from the four ecological landscapes. Snail specimens were clustered into three clades according to microbial community diversity, and thirty-seven genera that contributed to differential microbiota distributions were identified. Co-occurrence network analysis indicated a symbiotic relationship for the intestinal microbiota of O. hupensis, and PICRUSt analysis predicted forty-one metabolic functions in all snail samples, including membrane transport, amino acid metabolism, carbohydrate metabolism, replication and repair, energy metabolism, as well as xenobiotics biodegradation and metabolism. These findings improve our understanding of bacterial ecology in the O. hupensis intestine; further studies will focus on the relationship between O. hupensis intestinal microbiota and the microbiota in their specific ecological environments.

  • identification of high risk habitats of Oncomelania hupensis the intermediate host of schistosoma japonium in the poyang lake region china a spatial and ecological analysis
    PLOS Neglected Tropical Diseases, 2019
    Co-Authors: Yi Hu, Henry Lynn, Chengfang Lu, Shi-zhu Li, Michael P Ward, Shuang Xiao, Si Li, Jian Hu, Jun Zhang, Zhijie Zhang
    Abstract:

    Background Identifying and eliminating snail habitats is the key measure for schistosomiasis control, critical for the nationwide strategy of eliminating schistosomiasis in China. Here, our aim was to construct a new analytical framework to predict high-risk snail habitats based on a large sample field survey for Oncomelania hupensis, providing guidance for schistosomiasis control and prevention. Methodology/Principal findings Ten ecological models were constructed based on the occurrence data of Oncomelania hupensis and a range of variables in the Poyang Lake region of China, including four presence-only models (Maximum Entropy Models, Genetic Algorithm for rule-set Production, Bioclim and Domain) and six presence-absence models (Generalized Linear Models, Multivariate Adaptive Regression Splines, Flexible Discriminant Analysis, as well as machine algorithmic models–Random Forest, Classification Tree Analysis, Generalized Boosted Model), to predict high-risk snail habitats. Based on overall predictive performance, we found Presence-absence models outperformed the presence-only models and the models based on machine learning algorithms of classification trees showed the highest accuracy. The highest risk was located in the watershed of the River Fu in Yugan County, as well as the watershed of the River Gan and the River Xiu in Xingzi County, covering an area of 52.3 km2. The other high-risk areas for both snail habitats and schistosomiasis were mainly concentrated at the confluence of Poyang Lake and its five main tributaries. Conclusions/Significance This study developed a new distribution map of snail habitats in the Poyang Lake region, and demonstrated the critical role of ecological models in risk assessment to directing local field investigation of Oncomelania hupensis. Moreover, this study could also contribute to the development of effective strategies to prevent further spread of schistosomiasis from endemic areas to non-endemic areas.

  • toxicity of a molluscicide candidate ppu07 against Oncomelania hupensis gredler 1881 and local fish in field evaluation
    Chemosphere, 2019
    Co-Authors: Zhuo Chen, Weisi Wang, Hehua Hu, Shi-zhu Li, Xia Zhang, Huiyong Xu, Liping Duan
    Abstract:

    Abstract Schistosomiasis japonica caused by Schistosoma japonicum infection is recognized as a considerable economic and public health concern in Asia. Oncomelania hupensis is the sole intermediate host of S. japonicum. The only molluscicide recommended by World Health Organization (WHO) since 1960s is relative toxic to other aquatic species. In this article, we evaluated the novel molluscicide PPU07 in field trials on their efficiency against O. hupensis and toxicity for local fish. 25% PPU07 sulfate WP exhibited similar molluscicidal effect at 2.0 g/m2 and 2.0 g/m3 in the spraying and immersion trials with the WHO recommended molluscicide niclosamide (1 g/m2 and 1 g/m3). The mortality rates reached 95% and 96%, respectively. Moreover, little toxicity was observed for local fish and other aquatic organisms at the effective molluscicidal concentrations. In all, 25% PPU07 sulfate WP is a promising molluscicide for snail control, particularly in semi-commercial or commercial aquaculture ponds.

  • field evaluation of a novel molluscicide niclosamidate against Oncomelania hupensis intermediate host of schistosoma japonicum
    Parasitology Research, 2017
    Co-Authors: Weisi Wang, Hehua Hu, Shi-zhu Li, Huaming Zhang, Xia Zhang, Liping Duan
    Abstract:

    The molluscicidal activity of a novel molluscicide (niclosamidate) was evaluated in field trials against Oncomelania hupensis, the intermediate host of Schistosoma japonicum. The environmental safety of niclosamidate for local fishes was also studied under field conditions. The results showed that, at the dosages of 8.0 g/m2 and 4.0 g/m3, niclosamidate exhibits highly potent molluscicidal activity in the spraying and immersion trials, resulting in mortality rates of up to 81.8 and 72.7%, respectively. Its performance seems to be target-specific, with good molluscicidal ability observed for Oncomelania hupensis snails, but very low toxicity for local fishes and other aquatic organisms. The results suggest that niclosamidate can be used as an alternative molluscicide for snail control, which would be particularly applicable in semi-commercial or commercial aquaculture ponds.

Qingwu Jiang - One of the best experts on this subject based on the ideXlab platform.

  • spatio temporal variations of emerging sites infested with schistosome transmitting Oncomelania hupensis in hunan province china 1949 2016
    Parasites & Vectors, 2021
    Co-Authors: Ying Shi, Shurong Dong, Qingwu Jiang, Yingjian Wang, Yue Chen, Weicheng Deng, Guanghui Ren, Na Zhang, Yingyan Zheng, Yi-biao Zhou
    Abstract:

    Constant emerging sites infested with Oncomelania hupensis (O. hupensis) impede the goal realization of eliminating schistosomiasis. The study assessed the spatial and temporal distributions of new Oncomelania snail habitats in Hunan Province from 1949 to 2016. We used the data from annual snail surveys throughout Hunan Province for the period from 1949 to 2016. Global Moran’s I, Anselin local Moran’s I statistics (LISA) and a retrospective space-time permutation model were applied to determine the spatial and temporal distributions of emerging snail-infested sites. There were newly discovered snail-infested sites almost every year in 1949–2016, except for the years of 1993, 2009 and 2012. The number of emerging sites varied significantly in the five time periods (1949–1954, 1955–1976, 1977–1986, 1986–2003 and 2004–2016) (H = 25.35, p < 0.05). The emerging sites lasted 37.52 years in marshlands, 30.04 years in hills and 24.63 at inner embankments on average, with the values of Global Moran’s I being 0.52, 0.49 and 0.44, respectively. High-value spatial clusters (HH) were mainly concentrated along the Lishui River and in Xiangyin County. There were four marshland clusters, two hill clusters and three inner embankment clusters after 1976. Lower reaches of the Lishui River and the Dongting Lake estuary were the high-risk regions for new Oncomelania snail habitats with long durations. Snail surveillance should be strengthened at stubborn snail-infested sites at the inner embankments. Grazing prohibition in snail-infested grasslands should be a focus in marshlands. The management of bovines in Xiangyin County is of great importance.

  • Soil bacterial and fungal diversities and its putative association with the distribution of Oncomelania hupensis in the Dongting Lake marshlands, China
    Applied Soil Ecology, 2021
    Co-Authors: Ya Yang, Shurong Dong, Yingjian Wang, Wanting Cheng, Xiang Pan, Yu Yang, Jie Jiang, Dongjian Yang, Yue Chen, Qingwu Jiang
    Abstract:

    Abstract Oncomelania hupensis is the intermediate host of Schistosoma japonicum. In a marshland of Dongting Lake, the abundance of the snail plunged in 1999 and disappeared in 2000, for which the reasons remain unclear. Soil samples were collected from three locations: 1) Qianliang Lake where no snail was found, 2) Junshan Park where remained infested with O. hupensis and 3) Jianxin Farm in between. We compared the physicochemical characteristics and microbial compositions of soil samples from the three sites. All tested physicochemical characteristics of soil samples, except for pH, were similar for samples from Qianliang Lake and Junshan Park marshlands. Both bacterial and fungal community structures varied among the samples from three sites. Fungal diversity was significantly negatively correlated with moisture and total phosphorus and was positively correlated with fluoride and chloride. Soil microbial communities were different between sites with and without O. hupensis snails, but whether some identified abundant taxa are a reason for the disappearance of O. hupensis needs to be confirmed.

  • three gorges dam polynomial regression modeling of water level and the density of schistosome transmitting snails Oncomelania hupensis
    Parasites & Vectors, 2018
    Co-Authors: Ya Yang, Yi-biao Zhou, Wanting Cheng, Yu Yang, Yue Chen, Qingwu Jiang
    Abstract:

    Schistosomiasis remains a major public health concern in China. Oncomelania hupensis (O. hupensis) is the sole intermediate host of Schistosoma japonicum, and its change in distribution and density influences the endemic S. japonicum. The Three Gorges Dam (TGD) has substantially changed the downstream water levels of the dam. This study investigated the quantitative relationship between flooding duration and the density of the snail population. Two bottomlands without any control measures for snails were selected in Yueyang City, Hunan Province. Data for the density of the snail population and water level in both spring and autumn were collected for the period 2009–2015. Polynomial regression analysis was applied to explore the relationship between flooding duration and the density of the snail population. Data showed a convex relationship between spring snail density and flooding duration of the previous year (adjusted R2, aR2 = 0.61). The spring snail density remained low when the flooding duration was fewer than 50 days in the previous year, was the highest when the flooding duration was 123 days, and decreased thereafter. There was a similar convex relationship between autumn snail density and flooding duration of the current year (aR2 = 0.77). The snail density was low when the flooding duration was fewer than 50 days and was the highest when the flooding duration was 139 days. There was a convex relationship between flooding duration and the spring or autumn snail density. The snail density was the highest when flooding lasted about four to 5 months.

  • Three Gorges Dam: polynomial regression modeling of water level and the density of schistosome-transmitting snails Oncomelania hupensis
    'Springer Science and Business Media LLC', 2018
    Co-Authors: Ya Yang, Yi-biao Zhou, Wanting Cheng, Xiang Pan, Yu Yang, Yue Chen, Jianchuan Gao, Qingqing Dai, Lan Zhu, Qingwu Jiang
    Abstract:

    Abstract Background Schistosomiasis remains a major public health concern in China. Oncomelania hupensis (O. hupensis) is the sole intermediate host of Schistosoma japonicum, and its change in distribution and density influences the endemic S. japonicum. The Three Gorges Dam (TGD) has substantially changed the downstream water levels of the dam. This study investigated the quantitative relationship between flooding duration and the density of the snail population. Methods Two bottomlands without any control measures for snails were selected in Yueyang City, Hunan Province. Data for the density of the snail population and water level in both spring and autumn were collected for the period 2009–2015. Polynomial regression analysis was applied to explore the relationship between flooding duration and the density of the snail population. Results Data showed a convex relationship between spring snail density and flooding duration of the previous year (adjusted R 2, aR 2 = 0.61). The spring snail density remained low when the flooding duration was fewer than 50 days in the previous year, was the highest when the flooding duration was 123 days, and decreased thereafter. There was a similar convex relationship between autumn snail density and flooding duration of the current year (aR 2 = 0.77). The snail density was low when the flooding duration was fewer than 50 days and was the highest when the flooding duration was 139 days. Conclusions There was a convex relationship between flooding duration and the spring or autumn snail density. The snail density was the highest when flooding lasted about four to 5 months

  • advances in researches of molluscicidal microorganisms against Oncomelania hupensis
    Chinese journal of schistosomiasis control, 2016
    Co-Authors: Wanting Cheng, Yi-biao Zhou, Xiang Pan, Xiuxia Song, Qingwu Jiang
    Abstract:

    The elimination of Oncomelania hupensis snails is important to schistosomiasis control. Recently, the application of molluscicidal organisms is considered as a safe and efficient method for snail elimination. In order to provide scientific evidences for effective control of O. hupensis and schistosomiasis, this paper summarizes the researches of molluscicidal microorganisms against O. hupensis.

Related terms

Oncomelania hupensis - 15 days free trial to Access Experts & Abstracts