The Experts below are selected from a list of 258 Experts worldwide ranked by ideXlab platform
Igor Mucha - One of the best experts on this subject based on the ideXlab platform.
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ISCAS - Towards a true current Operational Amplifier
1994Co-Authors: Igor MuchaAbstract:(current input - curren output) Operational Amplifier structures are described and compared. The first one is a differential-input-single-output device, what fulfills the basic idea about Operational Amplifiers to provide a high differential gain. The second device is a single-inputdifferential-output Amplifier, what allows to exploit it as an adjoint element to the differential-input-single-output voltage Operational ‘Amplifier in current processing circuits interreciprocal to voltage processing circuits.
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Fully differential, current conveyor based CMOS Operational Amplifier
International Journal of Electronics, 1993Co-Authors: Igor MuchaAbstract:Abstract A fully differential, voltage mode CMOS Operational Amplifier is presented. The connection of two ‘current feedback’ Operational Amplifiers results in a structure which allows a wide unity-gain bandwidth to be achieved, without the slew-rate limitation by a quiescent current present in the ordinary Operational Amplifier architecture. The Operational Amplifier is realized in a standard CMOS technology, and can be integrated together with digital functions.
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Towards a true current Operational Amplifier [CMOS implementation]
Proceedings of IEEE International Symposium on Circuits and Systems - ISCAS '94, 1Co-Authors: Igor MuchaAbstract:Two true current (current input-current output) Operational Amplifier structures are described and compared. The first one is a differential-input-single-output device, that fulfills the basic idea about Operational Amplifiers to provide a high differential gain. The second device is a single-input-differential-output Amplifier, that allows one to exploit it as an adjoint element to the differential-input-single-output voltage Operational Amplifier in current processing circuits interreciprocal to voltage processing circuits. >
Rahul Sarpeshkar - One of the best experts on this subject based on the ideXlab platform.
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A Synthetic Microbial Operational Amplifier
ACS synthetic biology, 2018Co-Authors: Ji Zeng, Jaewook Kim, Areen Banerjee, Jonathan J. Y. Teo, Timothy W Chapman, Rahul SarpeshkarAbstract:Synthetic biology has created oscillators, latches, logic gates, logarithmically linear circuits, and load drivers that have electronic analogs in living cells. The ubiquitous Operational Amplifier, which allows circuits to operate robustly and precisely has not been built with biomolecular parts. As in electronics, a biological Operational-Amplifier could greatly improve the predictability of circuits despite noise and variability, a problem that all cellular circuits face. Here, we show how to create a synthetic three-stage inducer-input Operational Amplifier with a fast CRISPR-based differential-input push-pull stage, a slow transcription-and-translation amplification stage, and a fast-enzymatic output stage. Our "Bio-OpAmp" uses only 5 proteins including dCas9. It expands the toolkit of fundamental analog circuits in synthetic biology and provides a simple circuit motif for robust and precise molecular homeostasis.
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A Synthetic Microbial Operational Amplifier
2017Co-Authors: Ji Zeng, Jaewook Kim, Areen Banerjee, Rahul SarpeshkarAbstract:Synthetic biology has created oscillators, latches, logic gates, logarithmically linear circuits, and load drivers that have electronic analogs in living cells. The ubiquitous Operational Amplifier, which allows circuits to operate robustly and precisely has not been built with bio-molecular parts. As in electronics, a biological Operational-Amplifier could greatly improve the predictability of circuits despite noise and variability, a problem that all cellular circuits face. Here, we show how to create a synthetic 3-stage inducer-input Operational Amplifier with a differential transcription-factor stage, a CRISPR-based push-pull stage, and an enzymatic output stage with just 5 proteins including dCas9. Our "Bio-OpAmp" expands the toolkit of fundamental circuits available to bioengineers or biologists, and may shed insight into biological systems that require robust and precise molecular homeostasis and regulation.
Ji Zeng - One of the best experts on this subject based on the ideXlab platform.
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A Synthetic Microbial Operational Amplifier
ACS synthetic biology, 2018Co-Authors: Ji Zeng, Jaewook Kim, Areen Banerjee, Jonathan J. Y. Teo, Timothy W Chapman, Rahul SarpeshkarAbstract:Synthetic biology has created oscillators, latches, logic gates, logarithmically linear circuits, and load drivers that have electronic analogs in living cells. The ubiquitous Operational Amplifier, which allows circuits to operate robustly and precisely has not been built with biomolecular parts. As in electronics, a biological Operational-Amplifier could greatly improve the predictability of circuits despite noise and variability, a problem that all cellular circuits face. Here, we show how to create a synthetic three-stage inducer-input Operational Amplifier with a fast CRISPR-based differential-input push-pull stage, a slow transcription-and-translation amplification stage, and a fast-enzymatic output stage. Our "Bio-OpAmp" uses only 5 proteins including dCas9. It expands the toolkit of fundamental analog circuits in synthetic biology and provides a simple circuit motif for robust and precise molecular homeostasis.
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A Synthetic Microbial Operational Amplifier
2017Co-Authors: Ji Zeng, Jaewook Kim, Areen Banerjee, Rahul SarpeshkarAbstract:Synthetic biology has created oscillators, latches, logic gates, logarithmically linear circuits, and load drivers that have electronic analogs in living cells. The ubiquitous Operational Amplifier, which allows circuits to operate robustly and precisely has not been built with bio-molecular parts. As in electronics, a biological Operational-Amplifier could greatly improve the predictability of circuits despite noise and variability, a problem that all cellular circuits face. Here, we show how to create a synthetic 3-stage inducer-input Operational Amplifier with a differential transcription-factor stage, a CRISPR-based push-pull stage, and an enzymatic output stage with just 5 proteins including dCas9. Our "Bio-OpAmp" expands the toolkit of fundamental circuits available to bioengineers or biologists, and may shed insight into biological systems that require robust and precise molecular homeostasis and regulation.
Areen Banerjee - One of the best experts on this subject based on the ideXlab platform.
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A Synthetic Microbial Operational Amplifier
ACS synthetic biology, 2018Co-Authors: Ji Zeng, Jaewook Kim, Areen Banerjee, Jonathan J. Y. Teo, Timothy W Chapman, Rahul SarpeshkarAbstract:Synthetic biology has created oscillators, latches, logic gates, logarithmically linear circuits, and load drivers that have electronic analogs in living cells. The ubiquitous Operational Amplifier, which allows circuits to operate robustly and precisely has not been built with biomolecular parts. As in electronics, a biological Operational-Amplifier could greatly improve the predictability of circuits despite noise and variability, a problem that all cellular circuits face. Here, we show how to create a synthetic three-stage inducer-input Operational Amplifier with a fast CRISPR-based differential-input push-pull stage, a slow transcription-and-translation amplification stage, and a fast-enzymatic output stage. Our "Bio-OpAmp" uses only 5 proteins including dCas9. It expands the toolkit of fundamental analog circuits in synthetic biology and provides a simple circuit motif for robust and precise molecular homeostasis.
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A Synthetic Microbial Operational Amplifier
2017Co-Authors: Ji Zeng, Jaewook Kim, Areen Banerjee, Rahul SarpeshkarAbstract:Synthetic biology has created oscillators, latches, logic gates, logarithmically linear circuits, and load drivers that have electronic analogs in living cells. The ubiquitous Operational Amplifier, which allows circuits to operate robustly and precisely has not been built with bio-molecular parts. As in electronics, a biological Operational-Amplifier could greatly improve the predictability of circuits despite noise and variability, a problem that all cellular circuits face. Here, we show how to create a synthetic 3-stage inducer-input Operational Amplifier with a differential transcription-factor stage, a CRISPR-based push-pull stage, and an enzymatic output stage with just 5 proteins including dCas9. Our "Bio-OpAmp" expands the toolkit of fundamental circuits available to bioengineers or biologists, and may shed insight into biological systems that require robust and precise molecular homeostasis and regulation.
Jaewook Kim - One of the best experts on this subject based on the ideXlab platform.
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A Synthetic Microbial Operational Amplifier
ACS synthetic biology, 2018Co-Authors: Ji Zeng, Jaewook Kim, Areen Banerjee, Jonathan J. Y. Teo, Timothy W Chapman, Rahul SarpeshkarAbstract:Synthetic biology has created oscillators, latches, logic gates, logarithmically linear circuits, and load drivers that have electronic analogs in living cells. The ubiquitous Operational Amplifier, which allows circuits to operate robustly and precisely has not been built with biomolecular parts. As in electronics, a biological Operational-Amplifier could greatly improve the predictability of circuits despite noise and variability, a problem that all cellular circuits face. Here, we show how to create a synthetic three-stage inducer-input Operational Amplifier with a fast CRISPR-based differential-input push-pull stage, a slow transcription-and-translation amplification stage, and a fast-enzymatic output stage. Our "Bio-OpAmp" uses only 5 proteins including dCas9. It expands the toolkit of fundamental analog circuits in synthetic biology and provides a simple circuit motif for robust and precise molecular homeostasis.
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A Synthetic Microbial Operational Amplifier
2017Co-Authors: Ji Zeng, Jaewook Kim, Areen Banerjee, Rahul SarpeshkarAbstract:Synthetic biology has created oscillators, latches, logic gates, logarithmically linear circuits, and load drivers that have electronic analogs in living cells. The ubiquitous Operational Amplifier, which allows circuits to operate robustly and precisely has not been built with bio-molecular parts. As in electronics, a biological Operational-Amplifier could greatly improve the predictability of circuits despite noise and variability, a problem that all cellular circuits face. Here, we show how to create a synthetic 3-stage inducer-input Operational Amplifier with a differential transcription-factor stage, a CRISPR-based push-pull stage, and an enzymatic output stage with just 5 proteins including dCas9. Our "Bio-OpAmp" expands the toolkit of fundamental circuits available to bioengineers or biologists, and may shed insight into biological systems that require robust and precise molecular homeostasis and regulation.
