Synthetic Biology

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Tobias J. Erb - One of the best experts on this subject based on the ideXlab platform.

  • Revolutionizing agriculture with Synthetic Biology
    Nature Plants, 2019
    Co-Authors: Eleanore T. Wurtzel, Claudia E. Vickers, Andrew D. Hanson, A. Harvey Millar, Mark Cooper, Kai P. Voss-fels, Pablo I. Nikel, Tobias J. Erb
    Abstract:

    Synthetic Biology is here to stay and will transform agriculture if given the chance. The huge challenges facing food, fuel and chemical production make it vital to give Synthetic Biology that chance—notwithstanding the shifts in mindset, training and infrastructure investment this demands. Here, we assess opportunities for agricultural Synthetic Biology and ways to remove barriers to their realization. This Perspective assesses the opportunities and challenges for Synthetic Biology in revolutionizing agriculture, and highlights the resources and approaches we need to remove the barriers and propel another Green Revolution.

  • Revolutionizing agriculture with Synthetic Biology.
    Nature plants, 2019
    Co-Authors: Eleanore T. Wurtzel, Claudia E. Vickers, Andrew D. Hanson, A. Harvey Millar, Kai P. Voss-fels, Pablo I. Nikel, Mark E. Cooper, Tobias J. Erb
    Abstract:

    Synthetic Biology is here to stay and will transform agriculture if given the chance. The huge challenges facing food, fuel and chemical production make it vital to give Synthetic Biology that chance-notwithstanding the shifts in mindset, training and infrastructure investment this demands. Here, we assess opportunities for agricultural Synthetic Biology and ways to remove barriers to their realization.

M. Shapiro - One of the best experts on this subject based on the ideXlab platform.

  • Molecular Imaging in Synthetic Biology, and Synthetic Biology in Molecular Imaging.
    Molecular Imaging and Biology, 2017
    Co-Authors: Assaf A Gilad, M. Shapiro
    Abstract:

    Biomedical Synthetic Biology is an emerging field in which cells are engineered at the genetic level to carry out novel functions with relevance to biomedical and industrial applications. This approach promises new treatments, imaging tools, and diagnostics for diseases ranging from gastrointestinal inflammatory syndromes to cancer, diabetes, and neurodegeneration. As these cellular technologies undergo pre-clinical and clinical development, it is becoming essential to monitor their location and function in vivo, necessitating appropriate molecular imaging strategies, and therefore, we have created an interest group within the World Molecular Imaging Society focusing on Synthetic Biology and reporter gene technologies. Here, we highlight recent advances in biomedical Synthetic Biology, including bacterial therapy, immunotherapy, and regenerative medicine. We then discuss emerging molecular imaging approaches to facilitate in vivo applications, focusing on reporter genes for noninvasive modalities such as magnetic resonance, ultrasound, photoacoustic imaging, bioluminescence, and radionuclear imaging. Because reporter genes can be incorporated directly into engineered genetic circuits, they are particularly well suited to imaging Synthetic biological constructs, and developing them provides opportunities for creative molecular and genetic engineering.

Ruth Bastow - One of the best experts on this subject based on the ideXlab platform.

  • Opportunities in plant Synthetic Biology
    Journal of experimental botany, 2014
    Co-Authors: Charis Cook, Lisa Martin, Ruth Bastow
    Abstract:

    Synthetic Biology is an emerging field uniting scientists from all disciplines with the aim of designing or re-designing biological processes. Initially, Synthetic Biology breakthroughs came from microBiology, chemistry, physics, computer science, materials science, mathematics, and engineering disciplines. A transition to multicellular systems is the next logical step for Synthetic biologists and plants will provide an ideal platform for this new phase of research. This meeting report highlights some of the exciting plant Synthetic Biology projects, and tools and resources, presented and discussed at the 2013 GARNet workshop on plant Synthetic Biology.

C. Neal Stewart - One of the best experts on this subject based on the ideXlab platform.

  • Plant Synthetic Biology
    Trends in Plant Science, 2015
    Co-Authors: Wusheng Liu, C. Neal Stewart
    Abstract:

    Plant Synthetic Biology is an emerging field that combines engineering principles with plant Biology toward the design and production of new devices. This emerging field should play an important role in future agriculture for traditional crop improvement, but also in enabling novel bioproduction in plants. In this review we discuss the design cycles of Synthetic Biology as well as key engineering principles, genetic parts, and computational tools that can be utilized in plant Synthetic Biology. Some pioneering examples are offered as a demonstration of how Synthetic Biology can be used to modify plants for specific purposes. These include Synthetic sensors, Synthetic metabolic pathways, and Synthetic genomes. We also speculate about the future of Synthetic Biology of plants.

Eleanore T. Wurtzel - One of the best experts on this subject based on the ideXlab platform.

  • Revolutionizing agriculture with Synthetic Biology
    Nature Plants, 2019
    Co-Authors: Eleanore T. Wurtzel, Claudia E. Vickers, Andrew D. Hanson, A. Harvey Millar, Mark Cooper, Kai P. Voss-fels, Pablo I. Nikel, Tobias J. Erb
    Abstract:

    Synthetic Biology is here to stay and will transform agriculture if given the chance. The huge challenges facing food, fuel and chemical production make it vital to give Synthetic Biology that chance—notwithstanding the shifts in mindset, training and infrastructure investment this demands. Here, we assess opportunities for agricultural Synthetic Biology and ways to remove barriers to their realization. This Perspective assesses the opportunities and challenges for Synthetic Biology in revolutionizing agriculture, and highlights the resources and approaches we need to remove the barriers and propel another Green Revolution.

  • Revolutionizing agriculture with Synthetic Biology.
    Nature plants, 2019
    Co-Authors: Eleanore T. Wurtzel, Claudia E. Vickers, Andrew D. Hanson, A. Harvey Millar, Kai P. Voss-fels, Pablo I. Nikel, Mark E. Cooper, Tobias J. Erb
    Abstract:

    Synthetic Biology is here to stay and will transform agriculture if given the chance. The huge challenges facing food, fuel and chemical production make it vital to give Synthetic Biology that chance-notwithstanding the shifts in mindset, training and infrastructure investment this demands. Here, we assess opportunities for agricultural Synthetic Biology and ways to remove barriers to their realization.