The Experts below are selected from a list of 360 Experts worldwide ranked by ideXlab platform
Alan Hayes - One of the best experts on this subject based on the ideXlab platform.
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establishing an Operational Definition of sarcopenia in australia and new zealand delphi method based consensus statement
Journal of Nutrition Health & Aging, 2019Co-Authors: Jesse Zanker, David Scott, Esmee M Reijnierse, Sharon L Brennanolsen, Robin M Daly, Christian M Girgis, Mathis Grossmann, Alan HayesAbstract:Background: Globally there are several Operational Definitions for sarcopenia, complicating clinical and research applications. Objective: The objective of the Australian and New Zealand Society for Sarcopenia and Frailty Research (ANZSSFR) Task Force on Diagnostic Criteria for Sarcopenia was to reach consensus on the Operational Definition of sarcopenia for regional use by clinicians and researchers. Method: A four-Phase modified Delphi process was undertaken in which 24 individuals with expertise or a recognised interest in sarcopenia from different fields across Australia and New Zealand were invited to be Task Force members. An initial face-to-face meeting was held in Adelaide, South Australia, in November 2017, followed by two subsequent online Phases conducted by electronic surveys. A final Phase was used to approve the final statements. Responses were analysed using a pre-specified strategy. The level of agreement required for consensus was 80%. Results: In Phase 2, 94.1% of Task Force respondents voted in favour of adopting an existing Operational Definition of sarcopenia. In Phase 3, 94.4% of respondents voted in favour of adopting the European Working Group on Sarcopenia in Older People (EWGSOP) Definition as the Operational Definition for sarcopenia in Australia and New Zealand. Conclusion: With consensus achieved, the ANZSSFR will adopt, promote and validate the EWGSOP Operational Definition of sarcopenia for use by clinicians and researchers in Australia and New Zealand.
Leocadio Rodriguezmanas - One of the best experts on this subject based on the ideXlab platform.
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low relative mechanical power in older adults an Operational Definition and algorithm for its application in the clinical setting
Experimental Gerontology, 2020Co-Authors: Jose Losareyna, Julian Alcazar, Irene Rodriguezgomez, Ana Alfaroacha, Luis M Alegre, Leocadio Rodriguezmanas, Ignacio Ara, Francisco GarciagarciaAbstract:Abstract Introduction The assessment and treatment of low relative muscle power in older people has received little attention in the clinical setting when compared to sarcopenia. Our main goal was to assess the associations of low relative power and sarcopenia with other negative outcomes in older people. Methods The participants were 1189 subjects (54% women; 65–101 years old) from the Toledo Study for Healthy Aging. Probable sarcopenia was defined as having low handgrip strength, while confirmed sarcopenia also included low appendicular skeletal muscle index (assessed by dual energy X-ray absorptiometry) (EWGSOP2's Definition). Low relative (i.e. normalized to body mass) muscle power was assessed with the 5-repetition sit-to-stand power test (which uses an equation that converts sit-to-stand performance into mechanical power) and diagnosed in those subjects in the lowest sex-specific tertile. Low usual gait speed (UGS), frailty (according to Fried's criteria and the Frailty Trait Scale), limitations in basic (BADL) and instrumental activities of daily living (IADL) and poor quality of life were also recorded. Results Age-adjusted logistic regression analyses demonstrated that low relative muscle power was associated with low UGS (odds ratio (OR) = 1.9 and 2.5), frailty (OR = 3.9 and 4.7) and poor quality of life (OR = 1.8 and 1.9) in older men and women, respectively, and with limitations in BADL (OR = 1.6) and IADL (OR = 3.8) in older women (all p Conclusions Low relative muscle power had a greater clinical relevance than low handgrip strength and confirmed sarcopenia among older people. An Operational Definition and algorithm for low relative muscle power case finding in daily clinical practice was presented.
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a new Operational Definition of frailty the frailty trait scale
Journal of the American Medical Directors Association, 2014Co-Authors: Francisco Jose Garciagarcia, Laure Carcaillon, Jesus Angel Fernandeztresguerres, Ana Alfaro, Jose L Larrion, Carmen Josefina Contreras Castillo, Leocadio RodriguezmanasAbstract:Objectives: To provide a new instrument to diagnose frailty, the Frailty Trait Scale (FTS), that allows a more precise assessment and monitoring of individuals. Design: Prospective population-based cohort study. Setting: The Toledo Study for Healthy Aging, Spain. Participants: A total of 1972 men and women aged 65 years or older. Measurements: We identified 7 frailty dimensions (energy balanceenutrition, physical activity, nervous system, vascular system, strength, endurance, and gait speed) represented by 12 items. Each item was pondered based on the quintiles of its distribution in the study population. Validity was evaluated by testing its association with factors related to frailty and its predictive value for adverse events. This predictive capacity was further compared with the capacity of 2 well-established frailty models (the frailty phenotype and the Frailty Index). Results: FTS score was associated with several comorbidities and biomarkers classically associated with frailty. The FTS was associated with the incidence of hospitalization and mortality (hazard ratio associated with a score in the highest quartile [versus the first quartile] ¼ 2.3, 95% confidence interval [CI] 1.6 e3.4, and 2.5, 95% CI 1.8e3.6, respectively). Compared with Fried et al’ sd efinition, the FTS showed a better predictor for hospitalization in persons younger than 80 (area under the curve [AUC] ¼ 0.65 vs 0.62, P ¼ .01), and for mortality in the oldest group (AUC ¼ 0.77 vs 0.72, P ¼ .02). FTS showed similar predictive value to the Frailty Index. Conclusion: FTS associates with many of the factors linked to frailty and has a similar predictive capacity to that provided by the classical instruments. Its characteristics offer some advantages over them, with potential utility in research and clinical practice.
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searching for an Operational Definition of frailty a delphi method based consensus statement the frailty operative Definition consensus conference project
Journals of Gerontology Series A-biological Sciences and Medical Sciences, 2013Co-Authors: Leocadio Rodriguezmanas, Catherine Feart, Giovanni E Mann, Jose Vina, Somnath Chatterji, Wojciech Chodzkozajko, Magali Gonzalezcolaco Harmand, Howard Bergman, Laure CarcaillonAbstract:The concept of frailty has grown in importance because of a need for a better understanding of the health and functional status of older persons and a need to prevent or at least delay the onset of late-life disability and its adverse consequences (1). There is to date no clear consensus regarding the Definition of frailty (2,3). The most frequently used Definition (4) is focused on the evaluation of five domains (nutritional status, energy, physical activity, mobility, and strength) and has established five criteria (one per each domain: weight loss, exhaustion, leisure time activity, gait speed, and grip strength, respectively) for defining the frail phenotype and for identifying older persons at elevated risk for numerous adverse outcomes. However, other Definitions have been proposed, each with their own strengths and weaknesses (5). In addition to assessing physical functioning, many researchers believe that frailty Definitions should also include domains, such as cognition, mood, and other aspects of mental health (6,7). Frailty Definitions should be validated in a wide variety of cultural, economic, ethnic, and clinical settings (8) and demonstrate the predictive validity of frailty for adverse outcomes (9,10). The diagnosis of frailty relies currently on the assessment of a relatively small subset of easily measurable clinical markers (eg, Fried Criteria). While recognizing the multifactorial nature of frailty, it is important to develop an “Operational Definition” of frailty that is simple enough to be used clinically and to guide prevention and care. A working group of experts from a variety of fields related to frailty were invited to participate in a collaborative project, with the aim of developing the most complete and concrete Definition of frailty possible.
Torsten Norlander - One of the best experts on this subject based on the ideXlab platform.
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symbolic behavior in regular classrooms a specification of symbolic and non symbolic behavior
Frontiers in Psychology, 2011Co-Authors: Stefan Billinger, Torsten NorlanderAbstract:Students’ capabilities to use symbolic information in classroom setting could be expected to influence their possibilities to be active and participating. The development of strategies for teachers to compensate for reduced capability need specific Operational Definition of symbolic behavior. Fifty-three students, aged 11 to 13 years old, 29 boys and 24 girls, from three classes in the same Swedish compulsory regular school participated in the current study. After a short training sequence 25 students (47%) were defined as showing symbolic behavior (symbolic), and 28 students (53%) were not (non-symbolic), based on their follow-up test performances. Symbolic and non-symbolic differed significantly on post test performances (p. < .05). Surprisingly, non-symbolic behavior deteriorated their performance, while symbolic enhanced their performance (p. < .05). The results indicate that the Operational Definition used in the present study may be useful in further studies relating the capability to show symbolic behavior and students’ activity and participation in classroom settings.
Laure Carcaillon - One of the best experts on this subject based on the ideXlab platform.
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a new Operational Definition of frailty the frailty trait scale
Journal of the American Medical Directors Association, 2014Co-Authors: Francisco Jose Garciagarcia, Laure Carcaillon, Jesus Angel Fernandeztresguerres, Ana Alfaro, Jose L Larrion, Carmen Josefina Contreras Castillo, Leocadio RodriguezmanasAbstract:Objectives: To provide a new instrument to diagnose frailty, the Frailty Trait Scale (FTS), that allows a more precise assessment and monitoring of individuals. Design: Prospective population-based cohort study. Setting: The Toledo Study for Healthy Aging, Spain. Participants: A total of 1972 men and women aged 65 years or older. Measurements: We identified 7 frailty dimensions (energy balanceenutrition, physical activity, nervous system, vascular system, strength, endurance, and gait speed) represented by 12 items. Each item was pondered based on the quintiles of its distribution in the study population. Validity was evaluated by testing its association with factors related to frailty and its predictive value for adverse events. This predictive capacity was further compared with the capacity of 2 well-established frailty models (the frailty phenotype and the Frailty Index). Results: FTS score was associated with several comorbidities and biomarkers classically associated with frailty. The FTS was associated with the incidence of hospitalization and mortality (hazard ratio associated with a score in the highest quartile [versus the first quartile] ¼ 2.3, 95% confidence interval [CI] 1.6 e3.4, and 2.5, 95% CI 1.8e3.6, respectively). Compared with Fried et al’ sd efinition, the FTS showed a better predictor for hospitalization in persons younger than 80 (area under the curve [AUC] ¼ 0.65 vs 0.62, P ¼ .01), and for mortality in the oldest group (AUC ¼ 0.77 vs 0.72, P ¼ .02). FTS showed similar predictive value to the Frailty Index. Conclusion: FTS associates with many of the factors linked to frailty and has a similar predictive capacity to that provided by the classical instruments. Its characteristics offer some advantages over them, with potential utility in research and clinical practice.
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searching for an Operational Definition of frailty a delphi method based consensus statement the frailty operative Definition consensus conference project
Journals of Gerontology Series A-biological Sciences and Medical Sciences, 2013Co-Authors: Leocadio Rodriguezmanas, Catherine Feart, Giovanni E Mann, Jose Vina, Somnath Chatterji, Wojciech Chodzkozajko, Magali Gonzalezcolaco Harmand, Howard Bergman, Laure CarcaillonAbstract:The concept of frailty has grown in importance because of a need for a better understanding of the health and functional status of older persons and a need to prevent or at least delay the onset of late-life disability and its adverse consequences (1). There is to date no clear consensus regarding the Definition of frailty (2,3). The most frequently used Definition (4) is focused on the evaluation of five domains (nutritional status, energy, physical activity, mobility, and strength) and has established five criteria (one per each domain: weight loss, exhaustion, leisure time activity, gait speed, and grip strength, respectively) for defining the frail phenotype and for identifying older persons at elevated risk for numerous adverse outcomes. However, other Definitions have been proposed, each with their own strengths and weaknesses (5). In addition to assessing physical functioning, many researchers believe that frailty Definitions should also include domains, such as cognition, mood, and other aspects of mental health (6,7). Frailty Definitions should be validated in a wide variety of cultural, economic, ethnic, and clinical settings (8) and demonstrate the predictive validity of frailty for adverse outcomes (9,10). The diagnosis of frailty relies currently on the assessment of a relatively small subset of easily measurable clinical markers (eg, Fried Criteria). While recognizing the multifactorial nature of frailty, it is important to develop an “Operational Definition” of frailty that is simple enough to be used clinically and to guide prevention and care. A working group of experts from a variety of fields related to frailty were invited to participate in a collaborative project, with the aim of developing the most complete and concrete Definition of frailty possible.
Catherine Feart - One of the best experts on this subject based on the ideXlab platform.
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searching for an Operational Definition of frailty a delphi method based consensus statement the frailty operative Definition consensus conference project
Journals of Gerontology Series A-biological Sciences and Medical Sciences, 2013Co-Authors: Leocadio Rodriguezmanas, Catherine Feart, Giovanni E Mann, Jose Vina, Somnath Chatterji, Wojciech Chodzkozajko, Magali Gonzalezcolaco Harmand, Howard Bergman, Laure CarcaillonAbstract:The concept of frailty has grown in importance because of a need for a better understanding of the health and functional status of older persons and a need to prevent or at least delay the onset of late-life disability and its adverse consequences (1). There is to date no clear consensus regarding the Definition of frailty (2,3). The most frequently used Definition (4) is focused on the evaluation of five domains (nutritional status, energy, physical activity, mobility, and strength) and has established five criteria (one per each domain: weight loss, exhaustion, leisure time activity, gait speed, and grip strength, respectively) for defining the frail phenotype and for identifying older persons at elevated risk for numerous adverse outcomes. However, other Definitions have been proposed, each with their own strengths and weaknesses (5). In addition to assessing physical functioning, many researchers believe that frailty Definitions should also include domains, such as cognition, mood, and other aspects of mental health (6,7). Frailty Definitions should be validated in a wide variety of cultural, economic, ethnic, and clinical settings (8) and demonstrate the predictive validity of frailty for adverse outcomes (9,10). The diagnosis of frailty relies currently on the assessment of a relatively small subset of easily measurable clinical markers (eg, Fried Criteria). While recognizing the multifactorial nature of frailty, it is important to develop an “Operational Definition” of frailty that is simple enough to be used clinically and to guide prevention and care. A working group of experts from a variety of fields related to frailty were invited to participate in a collaborative project, with the aim of developing the most complete and concrete Definition of frailty possible.
