Osteolysis

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Giovanni Di Giacomo - One of the best experts on this subject based on the ideXlab platform.

  • does the presence of glenoid bone loss influence coracoid bone graft Osteolysis after the latarjet procedure a computed tomography scan study in 2 groups of patients with and without glenoid bone loss
    Journal of Shoulder and Elbow Surgery, 2014
    Co-Authors: Giovanni Di Giacomo, Alberto Costantini, Nicola De Gasperis, Andrea De Vita, Mario Rojas A Beccaglia, Nicole Pouliart
    Abstract:

    Background: Coracoid bone graft Osteolysis and fibrous union are the principal causes of failure in patients treated with the Latarjet procedure. This study aims to investigate the hypothesis that coracoid bone graft Osteolysis is more pronounced in cases without glenoid bone loss, which may be due to a diminished mechanotransduction effect at the bone healing site. Methods: We prospectively followed up 34 patients, treated with a mini-plate Latarjet procedure, divided into 2 groups (group A patients had glenoid bone loss >15% and group B patients had no glenoid bone loss). A computed tomography scan evaluation with 3-dimensional reconstruction was then performed on all patients to evaluate coracoid bone graft Osteolysis according to our coracoid bone graft Osteolysis classification. Results: The computed tomography scan analysis showed a different distribution of Osteolysis between group A and group B. The statistical analysis showed a significant difference (P 15%) than in those without it. Because factors of blood supply, compression, and surgical technique were the same for both groups, we believe that the mechanotransduction effect from the humeral head on the graft influences its remodeling. Conclusion: The results of this study suggest that the bone graft part of the Latarjet procedure plays a role in patients with significant coracoid bone loss but much less so when there is no bone loss.

  • coracoid bone graft Osteolysis after latarjet procedure a comparison study between two screws standard technique vs mini plate fixation
    International Journal of Shoulder Surgery, 2013
    Co-Authors: Giovanni Di Giacomo, Alberto Costantini, Nicola De Gasperis, Andrea De Vita, Bernard K H Lin, Marco Francone, Mario Rojas A Beccaglia, M Mastantuono
    Abstract:

    Aims: One of the reason for Latarjet procedure failure may be coracoid graft Osteolysis. In this study, we aimed to understand if a better compression between the coracoid process and the glenoid, using a mini‑plate fixation during the Latarjet procedure, could reduce the amount of coracoid graft Osteolysis. Materials and Methods: A computed tomography scan analysis of 26 prospectively followed‑up patients was conducted after modified Latarjet procedure using mini‑plate fixation technique to determine both the location and the amount of coracoid graft Osteolysis in them. We then compared our current results with results from that of our previous study without using mini‑plate fixation to determine if there is any statistical significant difference in terms of corcacoid bone graft Osteolysis between the two surgical techniques. Results: The most relevant Osteolysis was represented by the superficial part of the proximal coracoid, whereas the deep part of the proximal coracoid graft is least involved in Osteolysis and has best bone healing. The current study showed a significant difference only for the deep part of the distal coracoid with our previous study (P < 0.01). Discussion: To our knowledge, there are no studies in literature that show the causes of coracoid bone graft Osteolysis after Latarjet procedure. Conclusion: Our study suggests that there is a significant difference only for the deep part of the distal coracoid in terms of Osteolysis. At clinical examination, this difference did not correspond with any clinical findings. Level of Evidence: Level 4. Clinical Relevance: Prospective case series, Treatment study.

  • coracoid graft Osteolysis after the latarjet procedure for anteroinferior shoulder instability a computed tomography scan study of twenty six patients
    Journal of Shoulder and Elbow Surgery, 2011
    Co-Authors: Giovanni Di Giacomo, Alberto Costantini, Nicola De Gasperis, Andrea De Vita, Bernard K H Lin, Marco Francone, Mario Rojas A Beccaglia, M Mastantuono
    Abstract:

    Background: The Latarjet procedure has been advocated as an option for the treatment of anteroinferior shoulder instability in certain patients. However, progression of the transferred coracoid bone graft to Osteolysis has been reported in the literature. We propose that the coracoid bone graft Osteolysis could be one of the causes of failure of the Latarjet procedure. Materials and methods: A computed tomography scan analysis was done of 26 patients prospectively followed-up after the Latarjet procedure to determine the location and the amount of the coracoid graft Osteolysis. Results: The most relevant Osteolysis was represented by the superficial part of the proximal coracoid, whereas the distal region of the coracoid bone graft, especially in the deep portion, was the least involved in Osteolysis and had the best bone healing. Discussion: To our knowledge, this is the first study to quantify and localize coracoid Osteolysis after Latarjet procedure for anteroinferior shoulder instability using CT scan analysis. Conclusion: Our study suggests that the bone-block effect from the Latarjet procedure may not be the principal effect in its treatment of anteroinferior shoulder instability in patients without significant bony defects. Level of evidence: Level IV, Prospective Case Series, Treatment Study. 2011 Journal of Shoulder and Elbow Surgery Board of Trustees.

  • coracoid graft Osteolysis after the latarjet procedure for anteroinferior shoulder instability a computed tomography scan study of twenty six patients
    Journal of Shoulder and Elbow Surgery, 2011
    Co-Authors: Giovanni Di Giacomo, Alberto Costantini, Nicola De Gasperis, Andrea De Vita, Bernard K H Lin, Marco Francone, Mario Rojas A Beccaglia, M Mastantuono
    Abstract:

    Background The Latarjet procedure has been advocated as an option for the treatment of anteroinferior shoulder instability in certain patients. However, progression of the transferred coracoid bone graft to Osteolysis has been reported in the literature. We propose that the coracoid bone graft Osteolysis could be one of the causes of failure of the Latarjet procedure. Materials and methods A computed tomography scan analysis was done of 26 patients prospectively followed-up after the Latarjet procedure to determine the location and the amount of the coracoid graft Osteolysis. Results The most relevant Osteolysis was represented by the superficial part of the proximal coracoid, whereas the distal region of the coracoid bone graft, especially in the deep portion, was the least involved in Osteolysis and had the best bone healing. Discussion To our knowledge, this is the first study to quantify and localize coracoid Osteolysis after Latarjet procedure for anteroinferior shoulder instability using CT scan analysis. Conclusion Our study suggests that the bone-block effect from the Latarjet procedure may not be the principal effect in its treatment of anteroinferior shoulder instability in patients without significant bony defects.

M Mastantuono - One of the best experts on this subject based on the ideXlab platform.

  • coracoid bone graft Osteolysis after latarjet procedure a comparison study between two screws standard technique vs mini plate fixation
    International Journal of Shoulder Surgery, 2013
    Co-Authors: Giovanni Di Giacomo, Alberto Costantini, Nicola De Gasperis, Andrea De Vita, Bernard K H Lin, Marco Francone, Mario Rojas A Beccaglia, M Mastantuono
    Abstract:

    Aims: One of the reason for Latarjet procedure failure may be coracoid graft Osteolysis. In this study, we aimed to understand if a better compression between the coracoid process and the glenoid, using a mini‑plate fixation during the Latarjet procedure, could reduce the amount of coracoid graft Osteolysis. Materials and Methods: A computed tomography scan analysis of 26 prospectively followed‑up patients was conducted after modified Latarjet procedure using mini‑plate fixation technique to determine both the location and the amount of coracoid graft Osteolysis in them. We then compared our current results with results from that of our previous study without using mini‑plate fixation to determine if there is any statistical significant difference in terms of corcacoid bone graft Osteolysis between the two surgical techniques. Results: The most relevant Osteolysis was represented by the superficial part of the proximal coracoid, whereas the deep part of the proximal coracoid graft is least involved in Osteolysis and has best bone healing. The current study showed a significant difference only for the deep part of the distal coracoid with our previous study (P < 0.01). Discussion: To our knowledge, there are no studies in literature that show the causes of coracoid bone graft Osteolysis after Latarjet procedure. Conclusion: Our study suggests that there is a significant difference only for the deep part of the distal coracoid in terms of Osteolysis. At clinical examination, this difference did not correspond with any clinical findings. Level of Evidence: Level 4. Clinical Relevance: Prospective case series, Treatment study.

  • coracoid graft Osteolysis after the latarjet procedure for anteroinferior shoulder instability a computed tomography scan study of twenty six patients
    Journal of Shoulder and Elbow Surgery, 2011
    Co-Authors: Giovanni Di Giacomo, Alberto Costantini, Nicola De Gasperis, Andrea De Vita, Bernard K H Lin, Marco Francone, Mario Rojas A Beccaglia, M Mastantuono
    Abstract:

    Background: The Latarjet procedure has been advocated as an option for the treatment of anteroinferior shoulder instability in certain patients. However, progression of the transferred coracoid bone graft to Osteolysis has been reported in the literature. We propose that the coracoid bone graft Osteolysis could be one of the causes of failure of the Latarjet procedure. Materials and methods: A computed tomography scan analysis was done of 26 patients prospectively followed-up after the Latarjet procedure to determine the location and the amount of the coracoid graft Osteolysis. Results: The most relevant Osteolysis was represented by the superficial part of the proximal coracoid, whereas the distal region of the coracoid bone graft, especially in the deep portion, was the least involved in Osteolysis and had the best bone healing. Discussion: To our knowledge, this is the first study to quantify and localize coracoid Osteolysis after Latarjet procedure for anteroinferior shoulder instability using CT scan analysis. Conclusion: Our study suggests that the bone-block effect from the Latarjet procedure may not be the principal effect in its treatment of anteroinferior shoulder instability in patients without significant bony defects. Level of evidence: Level IV, Prospective Case Series, Treatment Study. 2011 Journal of Shoulder and Elbow Surgery Board of Trustees.

  • coracoid graft Osteolysis after the latarjet procedure for anteroinferior shoulder instability a computed tomography scan study of twenty six patients
    Journal of Shoulder and Elbow Surgery, 2011
    Co-Authors: Giovanni Di Giacomo, Alberto Costantini, Nicola De Gasperis, Andrea De Vita, Bernard K H Lin, Marco Francone, Mario Rojas A Beccaglia, M Mastantuono
    Abstract:

    Background The Latarjet procedure has been advocated as an option for the treatment of anteroinferior shoulder instability in certain patients. However, progression of the transferred coracoid bone graft to Osteolysis has been reported in the literature. We propose that the coracoid bone graft Osteolysis could be one of the causes of failure of the Latarjet procedure. Materials and methods A computed tomography scan analysis was done of 26 patients prospectively followed-up after the Latarjet procedure to determine the location and the amount of the coracoid graft Osteolysis. Results The most relevant Osteolysis was represented by the superficial part of the proximal coracoid, whereas the distal region of the coracoid bone graft, especially in the deep portion, was the least involved in Osteolysis and had the best bone healing. Discussion To our knowledge, this is the first study to quantify and localize coracoid Osteolysis after Latarjet procedure for anteroinferior shoulder instability using CT scan analysis. Conclusion Our study suggests that the bone-block effect from the Latarjet procedure may not be the principal effect in its treatment of anteroinferior shoulder instability in patients without significant bony defects.

Stuart B Goodman - One of the best experts on this subject based on the ideXlab platform.

  • murine model of progressive orthopedic wear particle induced chronic inflammation and Osteolysis
    Tissue Engineering Part C-methods, 2017
    Co-Authors: Jukka Pajarinen, Emmanuel Gibon, Akira Nabeshima, Tzuhua Lin, Taishi Sato, Eemeli Jamsen, Karthik Nathan, Zhenyu Yao, Stuart B Goodman
    Abstract:

    Periprosthetic Osteolysis and subsequent aseptic loosening of total joint replacements are driven by byproducts of wear released from the implant. Wear particles cause macrophage-mediated inflammation that culminates with periprosthetic bone loss. Most current animal models of particle-induced Osteolysis are based on the acute inflammatory reaction induced by wear debris, which is distinct from the slowly progressive clinical scenario. To address this limitation, we previously developed a murine model of periprosthetic Osteolysis that is based on slow continuous delivery of wear particles into the murine distal femur over a period of 4 weeks. The particle delivery was accomplished by using subcutaneously implanted osmotic pumps and tubing, and a hollow titanium rod press-fit into the distal femur. In this study, we report a modification of our prior model in which particle delivery is extended to 8 weeks to better mimic the progressive development of periprosthetic Osteolysis and allow the assessment of i...

  • selective inhibition of the mcp 1 ccr2 ligand receptor axis decreases systemic trafficking of macrophages in the presence of uhmwpe particles
    Journal of Orthopaedic Research, 2012
    Co-Authors: Emmanuel Gibon, Kate Fritton, Sandip Biswal, Lane R Smith, Stuart B Goodman
    Abstract:

    The biological mechanisms leading to periprosthetic Osteolysis involve both chemokines and the monocyte/macrophage cell lineage. Whether MCP-1 plays a major role in macrophage recruitment in the presence of wear particles is unknown. We tested two hypotheses: (1) that exogenous local delivery of MCP-1 induces systematic macrophage recruitment and (2) that blockade of the MCP-1 ligand-receptor axis decreases macrophage recruitment and Osteolysis in the presence of UHMWPE particles. Six groups of nude mice were used. We used non-invasive imaging to assay macrophage recruitment and Osteolysis. A murine macrophage cell line and primary wild type and CCR2 knockout murine macrophages were used as the reporter cells. Particles were infused into the femoral canal. Bioluminescence and immunohistochemical staining were used to confirm the migration of reporter cells. Locally infused MCP-1 induced systemic macrophage trafficking to bone. Injection of MCP-1 receptor antagonist significantly decreased reporter cell recruitment to bone infused with UHMWPE particles and decreased Osteolysis. Systemic migration of reporter cells to infused particles was decreased when the reporter cells were deficient in the CCR2 receptor. Interruption of the MCP-1 ligand-receptor axis appears to be a viable strategy to mitigate trafficking of macrophages and Osteolysis due to UHMWPE particles.

  • continuous infusion of uhmwpe particles induces increased bone macrophages and Osteolysis
    Clinical Orthopaedics and Related Research, 2011
    Co-Authors: Peigen Ren, Sandip Biswal, Afraaz R Irani, Zhinong Huang, Stuart B Goodman
    Abstract:

    Background Aseptic loosening and periprosthetic Osteolysis resulting from wear debris are major complications of total joint arthroplasty. Monocyte/macrophages are the key cells related to Osteolysis at the bone-implant interface of joint arthroplasties. Whether the monocyte/macrophages found at the implant interface in the presence of polyethylene particles are locally or systemically derived is unknown.

  • cellular profile and cytokine production at prosthetic interfaces study of tissues retrieved from revised hip and knee replacements
    Journal of Bone and Joint Surgery American Volume, 1998
    Co-Authors: Stuart B Goodman, William J Maloney, Phil Huie, Yong Song, David J Schurman, Steven T Woolson, Richard K Sibley
    Abstract:

    The tissues surrounding 65 cemented and 36 cementless total joint replacements undergoing revision were characterised for cell types by immunohistochemistry and for cytokine expression by in situ hybridisation. We identified three distinct groups of revised implants: loose implants with ballooning radiological Osteolysis, loose implants without Osteolysis, and well-fixed implants. In the cemented series, Osteolysis was associated with increased numbers of macrophages (p = 0.0006), T-lymphocyte subgroups (p = 0.03) and IL-1 (p = 0.02) and IL-6 (p = 0.0001) expression, and in the cementless series with increased numbers of T-lymphocyte subgroups (p = 0.005) and increased TNFα expression (p = 0.04). For cemented implants, the histological, histochemical and cytokine profiles of the interface correlated with the clinical and radiological grade of loosening and Osteolysis. Our findings suggest that there are different biological mechanisms of loosening and Osteolysis for cemented and cementless implants. T-lymphocyte modulation of macrophage function may be an important interaction at prosthetic interfaces.

William J Maloney - One of the best experts on this subject based on the ideXlab platform.

  • incidence and characteristics of Osteolysis in hxlpe tha at 16 year follow up in patients 50 years and less
    Journal of Arthroplasty, 2021
    Co-Authors: Richard D Rames, William J Maloney, Travis J Hillen, Gail Pashos, John C Clohisy
    Abstract:

    Abstract Introduction Young patients present a challenge for total hip arthroplasty (THA) survivorship. Highly cross-linked polyethylene (HXLPE) liners have decreased the prevalence of Osteolysis; however, concerns exist regarding the biologic activity of wear particles. The purpose of this study was to determine the incidence and characteristics of osteolytic lesions in young HXLPE THA patients at an average 16-year follow up and determine the ability to detect Osteolysis. Methods We performed a retrospective study involving 22 patients (26 THA) under age 50 at primary THA receiving HXLPE liners coupled with cobalt-chrome (CoCr) femoral heads. Computed tomography (CT) scans were reviewed for Osteolysis. Chi-squared analysis was used for categorical variables and unpaired Kruskal-Wallis rank-sum test for continuous variables. Logistic regression was used to compare wear rates between those patients with and without Osteolysis. Results The mean age at surgery was 38.5 years. The mean time from surgery to CT scan was sixteen years (range 14.25–19.5 years). Nine of the 26 THA showed Osteolysis. The mean volume of the lesions was 2.8 cm3. Linear (mean 0.008 mm/y) and volumetric (mean 4.5 mm3/year) wear rates were negligible. One-third of osteolytic lesions were visible on radiographs. Logistic regression failed to demonstrate a correlation between wear rates or UCLA activity score and Osteolysis. Conclusion We observed Osteolysis in 35% of HXLPE THA in young patients at mean 16-year follow up despite zero revisions for wear-related problems and clinically insignificant wear rates. Level of Evidence IV.

  • the incidence of acetabular Osteolysis in young patients with conventional versus highly crosslinked polyethylene
    Clinical Orthopaedics and Related Research, 2011
    Co-Authors: Nathan A Mall, William J Maloney, Ryan M Nunley, Jin Jun Zhu, Robert L Barrack, John C Clohisy
    Abstract:

    Background Osteolysis is a major mode of hip implant failure. Previous literature has focused on the amount of polyethylene wear comparing highly crosslinked polyethylene (HXPLE) with conventional liners but has not clarified the relative incidence of Osteolysis with these two liners.

  • fixation polyethylene wear and pelvic Osteolysis in primary total hip replacement
    Clinical Orthopaedics and Related Research, 1999
    Co-Authors: William J Maloney, Joshua J Jacobs, William H Harris, Paul F Lachiewicz, Jorge O Galante, Mike B Anderson, Victor M Goldberg, Matthew J Kraay, Harry E Rubash, Steve Schutzer
    Abstract:

    A multicenter retrospective review was performed analyzing 1081 primary total hip replacements in 944 patients using the Harris Galante-I cementless acetabular component with screw fixation. All patients were followed up for a minimum of 5 years with a mean followup of 81 months. Linear polyethylene wear averaged 0.11 mm/year (range, 0-0.86 mm/year). Pelvic Osteolysis was seen in 25 patients (2.3%). Migration of the acetabular component was seen in four hips. A subgroup of patients was reanalyzed at a minimum followup of 10 years. The mean linear polyethylene wear rate remained 0.11 mm/year. In this group, only one socket had migrated. There was an association between wear rate and age. On average, younger patients had higher wear rates. The risk for having pelvic Osteolysis develop and the need for revision surgery also was age-related. Twenty-two percent of hip replacements (15 hips) in patients younger than 50 years of age at the time of their index operation had pelvic Osteolysis develop. In contrast, for patients older than 50 years of age at the time of surgery only 7.8% (eight hips) had Osteolysis of the pelvis develop. For patients older than 70 years of age at the time of primary total hip replacement, none had pelvic Osteolysis develop.

  • Osteolysis in association with a total hip arthroplasty with ceramic bearing surfaces
    Journal of Bone and Joint Surgery American Volume, 1998
    Co-Authors: Taek Rim Yoon, Sung Man Rowe, Sung Taek Jung, Kwang Jin Seon, William J Maloney
    Abstract:

    The results of 103 total hip arthroplasties performed with insertion of a ceramic femoral head and acetabular component in ninety-six patients were reviewed to determine the radiographic prevalence of Osteolysis. After a mean duration of follow-up of ninety-two months (range, sixty to 125 months), femoral Osteolysis was observed in twenty-three hips (22 per cent), in one of two distinct patterns: linear Osteolysis (twelve hips) or scalloping expansile-type Osteolysis (eleven hips). The most common locations of Osteolysis in the femur were in zones I and VII as described by Gruen et al. Serial radiographs demonstrated that the extent of the Osteolysis progressed over time. Osteolysis of the pelvis, noted in forty-nine hips, was always associated with migration of the acetabular socket. No focal Osteolysis was observed in association with the stable sockets. Ten patients (ten hips) had a revision because of loosening and migration of the acetabular component. In three of these patients, the femoral stem also was revised. Gross examination revealed evidence of wear of the ceramic bearing surface in all ten patients. Scanning electron microscopy showed cracking and wear marks on the weight-bearing surface. Histological evaluation of the tissue in the periprosthetic membrane demonstrated abundant ceramic wear particles. The interface membrane was composed of a vascularized fibrous connective tissue with macrophages. Ultrastructurally, the macrophages contained numerous phagosomes of various sizes, with electron-dense material within the cytoplasm of the cell. The mean size of the ceramic particles, as determined with scanning electron microscopy, was 0.71 micrometer (range, 0.13 to 7.20 micrometers). This study supports the concept that ceramic wear particles can stimulate a foreign-body response and periprosthetic Osteolysis.

  • cellular profile and cytokine production at prosthetic interfaces study of tissues retrieved from revised hip and knee replacements
    Journal of Bone and Joint Surgery American Volume, 1998
    Co-Authors: Stuart B Goodman, William J Maloney, Phil Huie, Yong Song, David J Schurman, Steven T Woolson, Richard K Sibley
    Abstract:

    The tissues surrounding 65 cemented and 36 cementless total joint replacements undergoing revision were characterised for cell types by immunohistochemistry and for cytokine expression by in situ hybridisation. We identified three distinct groups of revised implants: loose implants with ballooning radiological Osteolysis, loose implants without Osteolysis, and well-fixed implants. In the cemented series, Osteolysis was associated with increased numbers of macrophages (p = 0.0006), T-lymphocyte subgroups (p = 0.03) and IL-1 (p = 0.02) and IL-6 (p = 0.0001) expression, and in the cementless series with increased numbers of T-lymphocyte subgroups (p = 0.005) and increased TNFα expression (p = 0.04). For cemented implants, the histological, histochemical and cytokine profiles of the interface correlated with the clinical and radiological grade of loosening and Osteolysis. Our findings suggest that there are different biological mechanisms of loosening and Osteolysis for cemented and cementless implants. T-lymphocyte modulation of macrophage function may be an important interaction at prosthetic interfaces.

Alberto Costantini - One of the best experts on this subject based on the ideXlab platform.

  • does the presence of glenoid bone loss influence coracoid bone graft Osteolysis after the latarjet procedure a computed tomography scan study in 2 groups of patients with and without glenoid bone loss
    Journal of Shoulder and Elbow Surgery, 2014
    Co-Authors: Giovanni Di Giacomo, Alberto Costantini, Nicola De Gasperis, Andrea De Vita, Mario Rojas A Beccaglia, Nicole Pouliart
    Abstract:

    Background: Coracoid bone graft Osteolysis and fibrous union are the principal causes of failure in patients treated with the Latarjet procedure. This study aims to investigate the hypothesis that coracoid bone graft Osteolysis is more pronounced in cases without glenoid bone loss, which may be due to a diminished mechanotransduction effect at the bone healing site. Methods: We prospectively followed up 34 patients, treated with a mini-plate Latarjet procedure, divided into 2 groups (group A patients had glenoid bone loss >15% and group B patients had no glenoid bone loss). A computed tomography scan evaluation with 3-dimensional reconstruction was then performed on all patients to evaluate coracoid bone graft Osteolysis according to our coracoid bone graft Osteolysis classification. Results: The computed tomography scan analysis showed a different distribution of Osteolysis between group A and group B. The statistical analysis showed a significant difference (P 15%) than in those without it. Because factors of blood supply, compression, and surgical technique were the same for both groups, we believe that the mechanotransduction effect from the humeral head on the graft influences its remodeling. Conclusion: The results of this study suggest that the bone graft part of the Latarjet procedure plays a role in patients with significant coracoid bone loss but much less so when there is no bone loss.

  • coracoid bone graft Osteolysis after latarjet procedure a comparison study between two screws standard technique vs mini plate fixation
    International Journal of Shoulder Surgery, 2013
    Co-Authors: Giovanni Di Giacomo, Alberto Costantini, Nicola De Gasperis, Andrea De Vita, Bernard K H Lin, Marco Francone, Mario Rojas A Beccaglia, M Mastantuono
    Abstract:

    Aims: One of the reason for Latarjet procedure failure may be coracoid graft Osteolysis. In this study, we aimed to understand if a better compression between the coracoid process and the glenoid, using a mini‑plate fixation during the Latarjet procedure, could reduce the amount of coracoid graft Osteolysis. Materials and Methods: A computed tomography scan analysis of 26 prospectively followed‑up patients was conducted after modified Latarjet procedure using mini‑plate fixation technique to determine both the location and the amount of coracoid graft Osteolysis in them. We then compared our current results with results from that of our previous study without using mini‑plate fixation to determine if there is any statistical significant difference in terms of corcacoid bone graft Osteolysis between the two surgical techniques. Results: The most relevant Osteolysis was represented by the superficial part of the proximal coracoid, whereas the deep part of the proximal coracoid graft is least involved in Osteolysis and has best bone healing. The current study showed a significant difference only for the deep part of the distal coracoid with our previous study (P < 0.01). Discussion: To our knowledge, there are no studies in literature that show the causes of coracoid bone graft Osteolysis after Latarjet procedure. Conclusion: Our study suggests that there is a significant difference only for the deep part of the distal coracoid in terms of Osteolysis. At clinical examination, this difference did not correspond with any clinical findings. Level of Evidence: Level 4. Clinical Relevance: Prospective case series, Treatment study.

  • coracoid graft Osteolysis after the latarjet procedure for anteroinferior shoulder instability a computed tomography scan study of twenty six patients
    Journal of Shoulder and Elbow Surgery, 2011
    Co-Authors: Giovanni Di Giacomo, Alberto Costantini, Nicola De Gasperis, Andrea De Vita, Bernard K H Lin, Marco Francone, Mario Rojas A Beccaglia, M Mastantuono
    Abstract:

    Background: The Latarjet procedure has been advocated as an option for the treatment of anteroinferior shoulder instability in certain patients. However, progression of the transferred coracoid bone graft to Osteolysis has been reported in the literature. We propose that the coracoid bone graft Osteolysis could be one of the causes of failure of the Latarjet procedure. Materials and methods: A computed tomography scan analysis was done of 26 patients prospectively followed-up after the Latarjet procedure to determine the location and the amount of the coracoid graft Osteolysis. Results: The most relevant Osteolysis was represented by the superficial part of the proximal coracoid, whereas the distal region of the coracoid bone graft, especially in the deep portion, was the least involved in Osteolysis and had the best bone healing. Discussion: To our knowledge, this is the first study to quantify and localize coracoid Osteolysis after Latarjet procedure for anteroinferior shoulder instability using CT scan analysis. Conclusion: Our study suggests that the bone-block effect from the Latarjet procedure may not be the principal effect in its treatment of anteroinferior shoulder instability in patients without significant bony defects. Level of evidence: Level IV, Prospective Case Series, Treatment Study. 2011 Journal of Shoulder and Elbow Surgery Board of Trustees.

  • coracoid graft Osteolysis after the latarjet procedure for anteroinferior shoulder instability a computed tomography scan study of twenty six patients
    Journal of Shoulder and Elbow Surgery, 2011
    Co-Authors: Giovanni Di Giacomo, Alberto Costantini, Nicola De Gasperis, Andrea De Vita, Bernard K H Lin, Marco Francone, Mario Rojas A Beccaglia, M Mastantuono
    Abstract:

    Background The Latarjet procedure has been advocated as an option for the treatment of anteroinferior shoulder instability in certain patients. However, progression of the transferred coracoid bone graft to Osteolysis has been reported in the literature. We propose that the coracoid bone graft Osteolysis could be one of the causes of failure of the Latarjet procedure. Materials and methods A computed tomography scan analysis was done of 26 patients prospectively followed-up after the Latarjet procedure to determine the location and the amount of the coracoid graft Osteolysis. Results The most relevant Osteolysis was represented by the superficial part of the proximal coracoid, whereas the distal region of the coracoid bone graft, especially in the deep portion, was the least involved in Osteolysis and had the best bone healing. Discussion To our knowledge, this is the first study to quantify and localize coracoid Osteolysis after Latarjet procedure for anteroinferior shoulder instability using CT scan analysis. Conclusion Our study suggests that the bone-block effect from the Latarjet procedure may not be the principal effect in its treatment of anteroinferior shoulder instability in patients without significant bony defects.