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J M Klossek - One of the best experts on this subject based on the ideXlab platform.

  • Paranasal Sinus fungus ball and surgery a review of 175 cases
    Rhinology, 2005
    Co-Authors: X Dufour, C Kauffmannlacroix, J C Ferrie, J M Goujon, Mariehelene Rodier, Alexandre Karkas, J M Klossek
    Abstract:

    Objective: To analyze the surgical results after Functional Endoscopic Sinus Surgery (FESS) in patients with Paranasal Sinus fungus ball. Material and methods: Retrospective analysis of the results of FESS performed in 175 patients suffering from Paranasal Sinus fungus balls. Results: All maxillary (n=150), sphenoidal (n= 20), and ethmoidal (n = 4) locations have been treated exclusively by FESS to obtain a wide opening of the affected Sinuses, allowing a careful extraction of all fungal material without removal of the inflamed mucous membrane. No major complication occurred. Postoperative care was reduced to nasal lavage with topical steroids for 3 to 6 weeks. Only I case of local failure have been observed (maxillary Sinus, n = 1), and 6 cases of persisting of fungus ball (maxillary Sinus, n = 4; frontal Sinus, n = 2) with a mean follow-up of 5 years. No medical treatment (antibiotic, antifungal) was required. Conclusion: Surgical treatment of a fungus ball consists in opening the infected Sinus cavity at the level of its ostium and removing fungal concretions while sparing the normal mucosa. No antifungal therapy is required. Finally, through this 175 patients study, FESS appears a reliable and safe surgical treatment with a low morbidity.

  • Paranasal Sinus fungus ball and surgery a review of 175 cases
    Rhinology, 2005
    Co-Authors: X Dufour, C Kauffmannlacroix, J C Ferrie, J M Goujon, Mariehelene Rodier, Alexandre Karkas, J M Klossek
    Abstract:

    Objective: To analyze the surgical results after Functional Endoscopic Sinus Surgery (FESS) in patients with Paranasal Sinus fungus ball. Material and methods: Retrospective analysis of the results of FESS performed in 175 patients suffering from Paranasal Sinus fungus balls. Results: All maxillary (n=150), sphenoidal (n= 20), and ethmoidal (n = 4) locations have been treated exclusively by FESS to obtain a wide opening of the affected Sinuses, allowing a careful extraction of all fungal material without removal of the inflamed mucous membrane. No major complication occurred. Postoperative care was reduced to nasal lavage with topical steroids for 3 to 6 weeks. Only I case of local failure have been observed (maxillary Sinus, n = 1), and 6 cases of persisting of fungus ball (maxillary Sinus, n = 4; frontal Sinus, n = 2) with a mean follow-up of 5 years. No medical treatment (antibiotic, antifungal) was required. Conclusion: Surgical treatment of a fungus ball consists in opening the infected Sinus cavity at the level of its ostium and removing fungal concretions while sparing the normal mucosa. No antifungal therapy is required. Finally, through this 175 patients study, FESS appears a reliable and safe surgical treatment with a low morbidity.

Joao N Lobo - One of the best experts on this subject based on the ideXlab platform.

  • the incidence of concha bullosa and its relationship to nasal septal deviation and Paranasal Sinus disease
    American Journal of Neuroradiology, 2004
    Co-Authors: Jamie S Stallman, Joao N Lobo
    Abstract:

    BACKGROUND AND PURPOSE: The incidence of middle turbinate pneumatization, or concha bullosa, has been well described in the literature. However, to our knowledge, no study has evaluated concha bullosa in relation to nasal septal deviation. We sought to analyze the incidence of concha bullosa and any correlation with nasal septal deviation and Paranasal Sinus disease. METHODS: Three neuroradiologists retrospectively reviewed findings of 1095 consecutive Paranasal Sinus CT studies conducted between 2001 and 2002. All examinations were performed for evaluation of a symptom referable to the sinonasal region. Paranasal Sinus inflammatory disease was identified and graded as mild, moderate, or severe. Sphenoid, ethmoid, maxillary, and frontal Sinuses were each graded separately on both sides. If a concha bullosa was present, it was graded in size as small, moderate, or large. If bilateral concha were present, sizes were compared and when one was larger, it was identified as dominant. When nasal septal deviation was present, it was graded as mild, moderate, or severe. The direction of nasal septal deviation was identified as the face of the convex surface. RESULTS: There was a clear association between the presence of a unilateral concha, or a dominant concha (in the case of bilateral concha), and the presence of nasal septal deviation (P < .0001). Moreover, there was a significant relationship between the presence of concha bullosa and deviation of the nasal septal to the contralateral side (P < .0001). This inverse association was present regardless of the size of the concha bullosa or degree of septal deviation. In every case, there was some preservation of air channels between the dominant concha and the nasal septum. Seventy-three percent of patients with concha bullosa had Paranasal Sinus inflammatory disease; 78% of patients without concha bullosa also had some form of inflammatory disease. CONCLUSION: Concha bullosa is a common anatomic variant. There is a strong association between the presence of a concha bullosa and contralateral deviation of the nasal septum. Nasal septal deviation away from the dominant concha, with preserved adjacent air channels, suggests that the deviation is not a direct result of mass effect from the concha. No increased incidence of Paranasal Sinus disease exists in patients with concha bullosa.

  • the incidence of concha bullosa and its relationship to nasal septal deviation and Paranasal Sinus disease
    American Journal of Neuroradiology, 2004
    Co-Authors: Jamie S Stallman, Joao N Lobo, Peter M Som
    Abstract:

    BACKGROUND AND PURPOSE: The incidence of middle turbinate pneumatization, or concha bullosa, has been well described in the literature. However, to our knowledge, no study has evaluated concha bullosa in relation to nasal septal deviation. We sought to analyze the incidence of concha bullosa and any correlation with nasal septal deviation and Paranasal Sinus disease. METHODS: Three neuroradiologists retrospectively reviewed findings of 1095 consecutive Paranasal Sinus CT studies conducted between 2001 and 2002. All examinations were performed for evaluation of a symptom referable to the sinonasal region. Paranasal Sinus inflammatory disease was identified and graded as mild, moderate, or severe. Sphenoid, ethmoid, maxillary, and frontal Sinuses were each graded separately on both sides. If a concha bullosa was present, it was graded in size as small, moderate, or large. If bilateral concha were present, sizes were compared and when one was larger, it was identified as dominant. When nasal septal deviation was present, it was graded as mild, moderate, or severe. The direction of nasal septal deviation was identified as the face of the convex surface. RESULTS: There was a clear association between the presence of a unilateral concha, or a dominant concha (in the case of bilateral concha), and the presence of nasal septal deviation (P CONCLUSION: Concha bullosa is a common anatomic variant. There is a strong association between the presence of a concha bullosa and contralateral deviation of the nasal septum. Nasal septal deviation away from the dominant concha, with preserved adjacent air channels, suggests that the deviation is not a direct result of mass effect from the concha. No increased incidence of Paranasal Sinus disease exists in patients with concha bullosa.

Jamie S Stallman - One of the best experts on this subject based on the ideXlab platform.

  • the incidence of concha bullosa and its relationship to nasal septal deviation and Paranasal Sinus disease
    American Journal of Neuroradiology, 2004
    Co-Authors: Jamie S Stallman, Joao N Lobo
    Abstract:

    BACKGROUND AND PURPOSE: The incidence of middle turbinate pneumatization, or concha bullosa, has been well described in the literature. However, to our knowledge, no study has evaluated concha bullosa in relation to nasal septal deviation. We sought to analyze the incidence of concha bullosa and any correlation with nasal septal deviation and Paranasal Sinus disease. METHODS: Three neuroradiologists retrospectively reviewed findings of 1095 consecutive Paranasal Sinus CT studies conducted between 2001 and 2002. All examinations were performed for evaluation of a symptom referable to the sinonasal region. Paranasal Sinus inflammatory disease was identified and graded as mild, moderate, or severe. Sphenoid, ethmoid, maxillary, and frontal Sinuses were each graded separately on both sides. If a concha bullosa was present, it was graded in size as small, moderate, or large. If bilateral concha were present, sizes were compared and when one was larger, it was identified as dominant. When nasal septal deviation was present, it was graded as mild, moderate, or severe. The direction of nasal septal deviation was identified as the face of the convex surface. RESULTS: There was a clear association between the presence of a unilateral concha, or a dominant concha (in the case of bilateral concha), and the presence of nasal septal deviation (P < .0001). Moreover, there was a significant relationship between the presence of concha bullosa and deviation of the nasal septal to the contralateral side (P < .0001). This inverse association was present regardless of the size of the concha bullosa or degree of septal deviation. In every case, there was some preservation of air channels between the dominant concha and the nasal septum. Seventy-three percent of patients with concha bullosa had Paranasal Sinus inflammatory disease; 78% of patients without concha bullosa also had some form of inflammatory disease. CONCLUSION: Concha bullosa is a common anatomic variant. There is a strong association between the presence of a concha bullosa and contralateral deviation of the nasal septum. Nasal septal deviation away from the dominant concha, with preserved adjacent air channels, suggests that the deviation is not a direct result of mass effect from the concha. No increased incidence of Paranasal Sinus disease exists in patients with concha bullosa.

  • the incidence of concha bullosa and its relationship to nasal septal deviation and Paranasal Sinus disease
    American Journal of Neuroradiology, 2004
    Co-Authors: Jamie S Stallman, Joao N Lobo, Peter M Som
    Abstract:

    BACKGROUND AND PURPOSE: The incidence of middle turbinate pneumatization, or concha bullosa, has been well described in the literature. However, to our knowledge, no study has evaluated concha bullosa in relation to nasal septal deviation. We sought to analyze the incidence of concha bullosa and any correlation with nasal septal deviation and Paranasal Sinus disease. METHODS: Three neuroradiologists retrospectively reviewed findings of 1095 consecutive Paranasal Sinus CT studies conducted between 2001 and 2002. All examinations were performed for evaluation of a symptom referable to the sinonasal region. Paranasal Sinus inflammatory disease was identified and graded as mild, moderate, or severe. Sphenoid, ethmoid, maxillary, and frontal Sinuses were each graded separately on both sides. If a concha bullosa was present, it was graded in size as small, moderate, or large. If bilateral concha were present, sizes were compared and when one was larger, it was identified as dominant. When nasal septal deviation was present, it was graded as mild, moderate, or severe. The direction of nasal septal deviation was identified as the face of the convex surface. RESULTS: There was a clear association between the presence of a unilateral concha, or a dominant concha (in the case of bilateral concha), and the presence of nasal septal deviation (P CONCLUSION: Concha bullosa is a common anatomic variant. There is a strong association between the presence of a concha bullosa and contralateral deviation of the nasal septum. Nasal septal deviation away from the dominant concha, with preserved adjacent air channels, suggests that the deviation is not a direct result of mass effect from the concha. No increased incidence of Paranasal Sinus disease exists in patients with concha bullosa.

X Dufour - One of the best experts on this subject based on the ideXlab platform.

  • Paranasal Sinus fungus ball and surgery a review of 175 cases
    Rhinology, 2005
    Co-Authors: X Dufour, C Kauffmannlacroix, J C Ferrie, J M Goujon, Mariehelene Rodier, Alexandre Karkas, J M Klossek
    Abstract:

    Objective: To analyze the surgical results after Functional Endoscopic Sinus Surgery (FESS) in patients with Paranasal Sinus fungus ball. Material and methods: Retrospective analysis of the results of FESS performed in 175 patients suffering from Paranasal Sinus fungus balls. Results: All maxillary (n=150), sphenoidal (n= 20), and ethmoidal (n = 4) locations have been treated exclusively by FESS to obtain a wide opening of the affected Sinuses, allowing a careful extraction of all fungal material without removal of the inflamed mucous membrane. No major complication occurred. Postoperative care was reduced to nasal lavage with topical steroids for 3 to 6 weeks. Only I case of local failure have been observed (maxillary Sinus, n = 1), and 6 cases of persisting of fungus ball (maxillary Sinus, n = 4; frontal Sinus, n = 2) with a mean follow-up of 5 years. No medical treatment (antibiotic, antifungal) was required. Conclusion: Surgical treatment of a fungus ball consists in opening the infected Sinus cavity at the level of its ostium and removing fungal concretions while sparing the normal mucosa. No antifungal therapy is required. Finally, through this 175 patients study, FESS appears a reliable and safe surgical treatment with a low morbidity.

  • Paranasal Sinus fungus ball and surgery a review of 175 cases
    Rhinology, 2005
    Co-Authors: X Dufour, C Kauffmannlacroix, J C Ferrie, J M Goujon, Mariehelene Rodier, Alexandre Karkas, J M Klossek
    Abstract:

    Objective: To analyze the surgical results after Functional Endoscopic Sinus Surgery (FESS) in patients with Paranasal Sinus fungus ball. Material and methods: Retrospective analysis of the results of FESS performed in 175 patients suffering from Paranasal Sinus fungus balls. Results: All maxillary (n=150), sphenoidal (n= 20), and ethmoidal (n = 4) locations have been treated exclusively by FESS to obtain a wide opening of the affected Sinuses, allowing a careful extraction of all fungal material without removal of the inflamed mucous membrane. No major complication occurred. Postoperative care was reduced to nasal lavage with topical steroids for 3 to 6 weeks. Only I case of local failure have been observed (maxillary Sinus, n = 1), and 6 cases of persisting of fungus ball (maxillary Sinus, n = 4; frontal Sinus, n = 2) with a mean follow-up of 5 years. No medical treatment (antibiotic, antifungal) was required. Conclusion: Surgical treatment of a fungus ball consists in opening the infected Sinus cavity at the level of its ostium and removing fungal concretions while sparing the normal mucosa. No antifungal therapy is required. Finally, through this 175 patients study, FESS appears a reliable and safe surgical treatment with a low morbidity.

K Inoue - One of the best experts on this subject based on the ideXlab platform.

  • Impact of intra-arterial chemotherapy including internal carotid artery for advanced Paranasal Sinus cancers involving the skull base
    British Journal of Cancer, 2014
    Co-Authors: J Yokoyama, S Ohba, M Fujimaki, T Anzai, M Kojima, K Ikeda, M Suzuki, H Yoshimoto, K Inoue
    Abstract:

    Background: The most significant problem of intra-arterial chemotherapy for advanced Paranasal Sinus carcinomas and residual cancers supplied by internal carotid artery (ICA) and involving the skull base is the lack of salvage therapies. Objective: The objective of the study was to evaluate the usefulness of intra-arterial chemotherapy including ICA infusion for treating advanced Paranasal Sinus carcinomas, which have invaded the skull base. Methods: Forty-six patients with advanced Paranasal Sinus carcinomas supplied by ICA were treated by intra-arterial chemotherapy using CDDP and sodium thiosulphate (STS) as a neutraliser of CDDP toxicity. After evaluating CT angiography, 150 mg m^−2 of CDDP was superselectively administered weekly to each feeding artery including ICA four times. Results: The 10-year overall survival rate and progression-free survival rate were 70.7 and 60.2%, respectively. Compared with control group without infusing ICA, recurrences at anterior skullbase or anterior ethomoid Sinus were significantly diminished. Of 32 patients in which the orbital apex had been invaded, 29 patients were treated with successful preservation of orbital contents. The CT angiography could efficiently determine all feeding arteries supplying the cancers. Consequently, chemotherapy could be administered on schedule, and side effects were minimal and acceptable. Conclusions: This new method has promising applications in the treatment of advanced Paranasal Sinus carcinomas involving the skull base.

  • Impact of intra-arterial chemotherapy including internal carotid artery for advanced Paranasal Sinus cancers involving the skull base
    British Journal of Cancer, 2014
    Co-Authors: Junkichi Yokoyama, Masataka Kojima, Mitsuhisa Fujimaki, Katsuhisa Ikeda, S Ohba, T Anzai, M Suzuki, H Yoshimoto, K Inoue
    Abstract:

    Impact of intra-arterial chemotherapy including internal carotid artery for advanced Paranasal Sinus cancers involving the skull base